PCIDB

KNApSAcK Metabolite C00004636

Metabolite

KNApSAcK Entry

id C00004636
Name Tamarixetin / 4'-O-Methylquercetin / 3,3',5,7-Tetrahydroxy-4'-methoxyflavone / 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
CAS RN 603-61-2
Standard InChI InChI=1S/C16H12O7/c1-22-11-3-2-7(4-9(11)18)16-15(21)14(20)13-10(19)5-8(17)6-12(13)23-16/h2-6,17-19,21H,1H3
Standard InChI (Main Layer) InChI=1S/C16H12O7/c1-22-11-3-2-7(4-9(11)18)16-15(21)14(20)13-10(19)5-8(17)6-12(13)23-16/h2-6,17-19,21H,1H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 3

Link

ChEMBL

By standard InChI CHEMBL226034
By standard InChI Main Layer CHEMBL226034

KEGG

By LinkDB C10188

CTD

By CAS RN

Human Protein / Gene in interaction

5 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P09917 Arachidonate 5-lipoxygenase Oxidoreductase CHEMBL226034 CHEMBL905752 (1)
0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 CHEMBL226034 CHEMBL1225717 (1)
0 / 0
P04792 Heat shock protein beta-1 Unclassified protein CHEMBL226034 CHEMBL993710 (1)
2 / 1
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 CHEMBL226034 CHEMBL1225718 (1)
4 / 4
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL226034 CHEMBL1225716 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#606595 Charcot-marie-tooth disease, axonal, type 2f; cmt2f P04792
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#608634 Neuronopathy, distal hereditary motor, type iib; hmn2b P04792
#604229 Peters anomaly Q16678

KEGG DISEASE (5)

KEGG disease name UniProt
H00856 Distal hereditary motor neuropathies (dHMN) P04792 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)