Species

KNApSAcK Entry

Organism name Achyrocline flaccida
Genus Achyrocline
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Achyrocline flaccida
Linked NCBI taxonomy ID 746492
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00004555 External link 512 Isognaphaliin
/ 5,8-Dihydroxy-3,7-dimethoxyflavone
/ 5,8-Dihydroxy-3,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one
No. 3 No. 15
C00004534 External link 512 3-Methylgalangin
/ Galangin 3-methyl ether
/ 5,7-Dihydroxy-3-methoxyflavone
/ 5,7-Dihydroxy-3-methoxy-2-phenyl-4H-1-benzopyran-4-one
CHEMBL1822221
1 / 1 / 0 No. 3 No. 15
C00004552 External link 512 8-Hydroxygalangin 3-methyl ether
/ 5,7,8-Trihydroxy-3-methoxyflavone
/ 5,7,8-Trihydroxy-3-methoxy-2-phenyl-4H-1-benzopyran-4-one
No. 3 No. 15
C00004636 External link 512 Tamarixetin
/ 4'-O-Methylquercetin
/ 3,3',5,7-Tetrahydroxy-4'-methoxyflavone
/ 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL226034
5 / 6 / 5 No. 3 No. 15
C00005059 External link 512 3,5,8-Trimethoxy-3',4'-methylenedioxy-7-prenyloxyflavone
/ 2-(1,3-Benzodioxol-5-yl)-3,5,8-trimethoxy-7-[(3-methyl-2-butenyl)oxy]-4H-1-benzopyran-4-one
No. 8 No. 15
C00008225 External link 512 Naringenin 5-methyl ether
/ Naringenin 5-O-methyl ether
/ 7,4'-Dihydroxy-5-methoxyflavanone
/ (-)-7,4'-Dihydroxy-5-methoxyflavanone
CHEMBL255035
CHEMBL501251
No. 25 No. 14
C00006954 External link 512 Helichrysetin
/ 4,2',4'-Trihydroxy-6'-methoxychalcone
CHEMBL507998
C061023
No. 92 No. 13
C00004989 External link 512 Gnaphaliin 7-epoxymethylbutyl ether
No. 4512
C00003929 External link 512 4'-Hydroxy-5-methoxy-7-(3-methyl-2,3-epoxybutoxy)flavone
No. 4512
C00008163 External link 512 5-Hydroxy-7-(3-methyl-2,3-epoxybutoxy)flavanone
No. 4533

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00004636 0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00004636 0 / 0
P08183 Multidrug resistance protein 1 drug C00004534 1 / 0
P04792 Heat shock protein beta-1 Unclassified protein C00004636 2 / 1
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00004636 4 / 4
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00004636 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#606595 Charcot-marie-tooth disease, axonal, type 2f; cmt2f P04792
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#612244 Inflammatory bowel disease 13; ibd13 P08183
#608634 Neuronopathy, distal hereditary motor, type iib; hmn2b P04792
#604229 Peters anomaly Q16678

KEGG DISEASE (5)

KEGG name UniProt
H00856 Distal hereditary motor neuropathies (dHMN) P04792 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)