Species

KNApSAcK Entry

Organism name Amomum koenigii
Genus Amomum
Family Zingiberaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Amomum koenigii
Linked NCBI taxonomy ID 252851
Linked level species

Family

Family in NCBI taxonomy Zingiberaceae
ID 4642

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (12)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00004569 External link 512 Jaranol
/ Kumatakenin
/ Kumatakillin
/ Kaempferol 3,7-O-dimethyl ether
/ 5,4'-Dihydroxy-3,7-dimethoxyflavone
/ 5-Hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one
CHEMBL349724
No. 3 No. 15
C00013357 External link 512 3,7-Dihydroxy-5,3',4'-trimethoxyflavone
/ 2-(3,4-Dimethoxyphenyl)-3,7-dihydroxy-5-methoxy-4H-1-benzopyran-4-one
CHEMBL2043333
No. 3 No. 15
C00004643 External link 512 Ombuin
/ 4',7-Dimethylquercetin
/ 3,5,3'-Trihydroxy-7,4'-dimethoxyflavone
/ 3,5-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one
CHEMBL75589
1 / 1 / 1 No. 3 No. 15
C00004647 External link 512 Ayanin
/ 3,7,4'-Tri-O-methylquercetin
/ 5,3'-Dihydroxy-3,7,4'-trimethoxyflavone
/ 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one
CHEMBL74898
18 / 10 / 2 No. 3 No. 15
C00013349 External link 512 3,7-Dihydroxy-5,4'-dimethoxyflavone
/ 3,7-Dihydroxy-5-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
No. 3 No. 15
C00004649 External link 512 Quercetin 7,3',4'-trimethyl ether
/ 3,5-Dihydroxy-7,3',4'-trimethoxyflavone
/ 2-(3,4-Dimethoxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one
CHEMBL1689343
1 / 2 / 0 No. 3 No. 15
C00013350 External link 512 Tetramethylkaempferol
/ O-Tetramethylkaempferol
/ 3,5,7,4'-Tetramethoxyflavone
/ 2-(4-Methoxyphenyl)-3,5,7-trimethoxy-4-oxo-4H-1-benzopyran
/ 3,5,7-Trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL356036
1 / 0 / 0 No. 8 No. 15
C00004653 External link 512 Retusine
/ Retusin(Ariocarpus)
/ Quercetin 3,7,3',4'-tetramethyl ether
/ 5-Hydroxy-3,7,3',4'-tetramethoxyflavone
/ 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one
CHEMBL77966
3 / 3 / 0 No. 8 No. 15
C00004655 External link 512 Quercetin pentamethyl ether
/ 3,5,7,3',4'-Pentamethoxyflavone
CHEMBL19032
16 / 10 / 12 No. 8 No. 15
C00004573 External link 512 3,7,4'-Tri-O-methylkaempferol
/ Kaempferol 3,7,4'-trimethyl ether
/ 5-Hydroxy-3,7,4'-trimethoxyflavone
/ 5-Hydroxy-3,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL77686
No. 35 No. 15
C00040818 External link 512 3-Hydroxy-5,7,4'-trimethoxyflavone
No. 35 No. 15
C00041254 External link 512 1-Methoxy-E-4-eicosen-3-one
/ (E)-1-Methoxy-4-eicosen-3-one
No. 7793

Human Protein / Gene in interactions

34 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00004647 C00004649 C00004653 C00004655 2 / 0
P33527 Multidrug resistance-associated protein 1 drugs C00004647 C00004653 C00004655 0 / 0
P08183 Multidrug resistance protein 1 drug C00004647 C00004653 1 / 0
O00255 Menin Unclassified protein C00004655 2 / 5
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00004655 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00004655 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00004655 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00004655 2 / 2
P39748 Flap endonuclease 1 Enzyme C00004655 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00004655 0 / 0
Q12791 Calcium-activated potassium channel subunit alpha-1 KCNM, KCa1.x C00004655 1 / 1
P28482 Mitogen-activated protein kinase 1 Erk C00004655 0 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00013350 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00004655 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00004655 0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00004655 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00004655 1 / 1
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00004643 1 / 1
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00004655 1 / 2
Q13748 Tubulin alpha-3C/D chain Structural C00004647 0 / 0
P68366 Tubulin alpha-4A chain Structural C00004647 0 / 0
Q9H4B7 Tubulin beta-1 chain Structural C00004647 1 / 0
P04350 Tubulin beta-4A chain Structural C00004647 2 / 0
Q3ZCM7 Tubulin beta-8 chain Structural C00004647 0 / 0
P07437 Tubulin beta chain Structural C00004647 0 / 0
Q71U36 Tubulin alpha-1A chain Structural C00004647 1 / 1
P68371 Tubulin beta-4B chain Structural C00004647 0 / 0
Q13509 Tubulin beta-3 chain Structural C00004647 2 / 1
P68363 Tubulin alpha-1B chain Unclassified protein C00004647 0 / 0
Q13885 Tubulin beta-2A chain Structural C00004647 0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein C00004647 0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein C00004647 0 / 0
Q9BUF5 Tubulin beta-6 chain Structural C00004647 0 / 0
Q9BVA1 Tubulin beta-2B chain Structural C00004647 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#614490 Blood group, junior system; jr Q9UNQ0
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#609446 Generalized epilepsy and paroxysmal dyskinesia; gepd Q12791
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#612244 Inflammatory bowel disease 13; ibd13 P08183
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#611603 Lissencephaly 3; lis3 Q71U36
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#278300 Xanthinuria, type i P47989

KEGG DISEASE (15)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00192 Xanthinuria P47989 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H01258 Generalized epilepsy and paroxysmal dyskinesia (GEPD) Q12791 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)