Mirabilis viscosa
Species
KNApSAcK Entry
| Organism name | Mirabilis viscosa |
|---|---|
| Genus | Mirabilis |
| Family | Nyctaginaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Mirabilis |
|---|---|
| Linked NCBI taxonomy ID | 3537 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Nyctaginaceae |
|---|---|
| ID | 3536 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Metabolite list (17)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001016
|
7-O-Methylacacetin
/ Acacetin 7-methyl ether / Genkwanin 4'-methyl ether / Apigenin 7,4'-dimethyl ether / 5-Hydroxy-4',7-dimethoxyflavone / 5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL350958
|
C044998
|
1 / 0 / 0 | No. 3 | No. 15 |
|
|
|
C00001060
|
Kaempferide
|
CHEMBL40919
|
6 / 7 / 4 | No. 3 | No. 15 |
|
||
|
C00003867
|
Velutin
/ Flavoyadorigenin B / Luteolin 7,3'-dimethyl ether / 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL508292
|
No. 3 | No. 15 |
|
|||
|
C00004567
|
Rhamnocitrin
/ 7-Methylkaempferol / 3,4',5-Trihydroxy-7-methoxyflavone / 3,5-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL442289
|
No. 3 | No. 15 |
|
|||
|
C00004569
|
Jaranol
/ Kumatakenin / Kumatakillin / Kaempferol 3,7-O-dimethyl ether / 5,4'-Dihydroxy-3,7-dimethoxyflavone / 5-Hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL349724
|
No. 3 | No. 15 |
|
|||
|
C00004570
|
Ermanin
/ Kaempferol 3,4'-di-O-methyl ether / 5,7-Dihydroxy-3,4'-dimethoxyflavone / 5,7-Dihydroxy-3-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL309061
|
C104804
|
2 / 1 / 1 | No. 3 | No. 15 |
|
|
|
C00004571
|
Kaempferol 7,4'-dimethyl ether
/ 3,5-Dihydroxy-7,4'-dimethoxyflavone / 3,5-Dihydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
No. 3 | No. 15 |
|
||||
|
C00004693
|
Jaceidin
/ Quercetagetin 3,3',6-trimethyl ether / 5,7,4'-Trihydroxy-3,6,3'-trimethoxyflavone |
CHEMBL161878
|
No. 3 | No. 15 |
|
|||
|
C00004649
|
Quercetin 7,3',4'-trimethyl ether
/ 3,5-Dihydroxy-7,3',4'-trimethoxyflavone / 2-(3,4-Dimethoxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL1689343
|
1 / 2 / 0 | No. 3 | No. 15 |
|
||
|
C00004635
|
Isorhamnetin
/ 3'-O-Methylquercetin / 3,4',5,7-Tetrahydroxy-3'-methoxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL379064
|
C047368
|
12 / 10 / 13 | 10 / 0 | No. 3 | No. 15 |
|
|
C00004638
|
Quercetin 3,7-dimethyl ether
/ 5,3',4'-Trihydroxy-3,7-dimethoxyflavone / 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL164861
|
C065497
|
2 / 1 / 2 | No. 3 | No. 15 |
|
|
|
C00004639
|
Quercetin 3,3'-dimethyl ether
/ 5,7,4'-Trihydroxy-3,3'-dimethoxyflavone / 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-methoxy-4H-1-benzopyran-4-one |
CHEMBL511363
|
C060385
|
No. 3 | No. 15 |
|
||
|
C00004642
|
Rhamnazin
/ 7,3'-Di-O-methylquercetin / 3,4',5-Trihydroxy-3',7-dimethoxyflavone / 3,5-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL457148
|
No. 3 | No. 15 |
|
|||
|
C00004646
|
Pachypodol
/ Quercetin 3,3',7-trimethyl ether / 5,4'-Dihydroxy-3,7,3'-trimethoxyflavone / 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL165180
|
C008751
|
1 / 2 / 0 | No. 3 | No. 15 |
|
|
|
C00004600
|
3,5,7-Trihydroxy-6,4'-dimethoxyflavone
/ 6,4'-Dimethoxy-3,5,7-trihydroxyflavone |
CHEMBL311155
|
No. 3 | No. 15 |
|
|||
|
C00004653
|
Retusine
/ Retusin(Ariocarpus) / Quercetin 3,7,3',4'-tetramethyl ether / 5-Hydroxy-3,7,3',4'-tetramethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL77966
|
3 / 3 / 0 | No. 8 | No. 15 |
|
||
|
C00004573
|
3,7,4'-Tri-O-methylkaempferol
/ Kaempferol 3,7,4'-trimethyl ether / 5-Hydroxy-3,7,4'-trimethoxyflavone / 5-Hydroxy-3,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL77686
|
No. 35 | No. 15 |
|
Human Protein / Gene in interactions
21 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001060 C00004646 C00004649 C00004653 | 2 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001060 C00004635 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00001060 C00004635 | 0 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00001060 C00004635 | 4 / 4 |
| P08183 | Multidrug resistance protein 1 | drug | C00001060 C00004653 | 1 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00004635 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00004635 | 1 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00004570 | 1 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00004635 | 0 / 0 |
| P04792 | Heat shock protein beta-1 | Unclassified protein | C00004635 | 2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00001016 | 0 / 0 |
| P00747 | Plasminogen | S1A | C00004638 | 1 / 2 |
| P04745 | Alpha-amylase 1 | Enzyme | C00004635 | 0 / 0 |
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00004638 | 0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00004653 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00001060 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00004570 | 0 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00004635 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00004635 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00004635 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00004635 | 1 / 2 |
10 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00004635
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00004635
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00004635
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00004635
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00004635
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00004635
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00004635
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00004635
|
| 4973 | OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
C00004635
|
| 7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 |
C00004635
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (15)
| OMIM | preferred title | UniProt |
|---|---|---|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #606595 | Charcot-marie-tooth disease, axonal, type 2f; cmt2f |
P04792
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #608634 | Neuronopathy, distal hereditary motor, type iib; hmn2b |
P04792
|
| #604229 | Peters anomaly |
Q16678
|
| #217090 | Plasminogen deficiency, type i |
P00747
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #278300 | Xanthinuria, type i |
P47989
|
KEGG DISEASE (16)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00223 | Inherited thrombophilia |
P00747
(related)
|
| H01206 | Plasminogen deficiency |
P00747
(related)
|
| H00856 | Distal hereditary motor neuropathies (dHMN) |
P04792
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|