Cryptomeria japonica

• Index
• Plant Species
• Metabolite list (45)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Cryptomeria japonica
Genus	Cryptomeria
Family	Taxodiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Cryptomeria japonica
Linked NCBI taxonomy ID	3369
Linked level	species

Family

Family in NCBI taxonomy	Cupressaceae
ID	3367

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Spermatophyta
ID	58024

Metabolite list (45)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00004653	Retusine / Retusin(Ariocarpus) / Quercetin 3,7,3',4'-tetramethyl ether / 5-Hydroxy-3,7,3',4'-tetramethoxyflavone / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one	CHEMBL77966		3 / 3 / 0		No. 8	No. 15
C00009092	[Catechin-(4alpha->8)]2-epicatechin	CHEMBL290632		13 / 5 / 6		No. 29	No. 19
C00009091	Procyanidin C2	CHEMBL290632		13 / 5 / 6		No. 29	No. 19
C00006501	Amentoflavone 7,4',7'',4'''-tetramethyl ether	CHEMBL378516		1 / 0 / 0		No. 34	No. 18
C00006536	Cryptomerin A					No. 34	No. 18
C00006485	3'''-Hydroxyamentoflavone					No. 34	No. 18
C00006538	Cryptomerin B					No. 34	No. 18
C00004573	3,7,4'-Tri-O-methylkaempferol / Kaempferol 3,7,4'-trimethyl ether / 5-Hydroxy-3,7,4'-trimethoxyflavone / 5-Hydroxy-3,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one	CHEMBL77686				No. 35	No. 15
C00021272	Cubebol / (-)-Cubebol / Cubeb camphor					No. 197	No. 38
C00031766	Epicubebol / epi-Cubebol / 4-epi-Cubebol					No. 197	No. 38
C00020066	T-Cadinol / epi-alpha-Cadinol	CHEMBL486795	C072576			No. 205	No. 38
C00031284	Sandaracopimarinal					No. 208	No. 48
C00031283	Sandaracopimaric acid / (-)-Sandaracopimaric acid	CHEMBL513197 CHEMBL1397211 CHEMBL1410398 CHEMBL1735595	C082072	14 / 13 / 7		No. 208	No. 48
C00031286	Sandaracopimarinol acetate					No. 208	No. 48
C00031285	Sandaracopimarinol					No. 208	No. 48
C00000606	(-)-Matairesinol	CHEMBL425148	C068935	1 / 0 / 0		No. 223	No. 21
C00007203	(+)-Wikstromol / (+)-Nortrachelogenin	CHEMBL453799 CHEMBL1483370		3 / 2 / 2		No. 223	No. 21
C00000604	(-)-Secoisolariciresinol	CHEMBL368347	C060283	2 / 1 / 1	1 / 0	No. 282	No. 21
C00012765	Proximadiol / Cryptomeridiol / Selina-4,7-diol / Selinane-4alpha,11-diol	CHEMBL465860 CHEMBL1288770				No. 351
C00031398	Sugiol / (+)-Sugiol	CHEMBL195296				No. 355
C00029572	6alpha-Hydroxysuginyl methyl ether					No. 355
C00031522	19-Hydroxyferruginol	CHEMBL197310				No. 359	No. 40
C00035987	bietatriene / Dehydroabietane / Abieta-8,11,13-triene					No. 359	No. 40
C00007204	Isolariciresinol / (+)-Isolariciresinol	CHEMBL399512 CHEMBL1760593	C060284	2 / 1 / 1		No. 406
C00002591	(-)-Cubebin / beta-Cubebin / (-)-beta-Cubebin / (8R,8'R,9S)-Cubebin	CHEMBL182001 CHEMBL399831	C433065	2 / 1 / 1	0 / 2	No. 629	No. 21
C00002609	Hinokiol / (+)-Hinokiol	CHEMBL16901		26 / 24 / 20		No. 761	No. 23
C00020074	Calamenene / (-)-cis-Calamenene					No. 824
C00031571	Agatharesinol					No. 922	No. 24
C00031369	Sequirin C	CHEMBL1689216				No. 922	No. 24
C00031792	Formosaninol / (+)-Formosaninol					No. 1508
C00032254	Sugikurojin C / (-)-Sugikurojin C					No. 1508
C00007636	delta-Cadinene	CHEMBL445759				No. 1524	No. 39
C00002657	p-Formylphenol / 4-Hydroxybenzaldehyde / p-Hydroxybenzaldehyde	CHEMBL14193	C011483	3 / 2 / 2		No. 2076
C00031626	beta-Elemol					No. 2406
C00032262	Sequirin A / Sugiresinol					No. 2651	No. 24
C00023987	LL-P880alpha / (-)-Pestalotin					No. 3287
C00011647	(-)-Cryptomerione / (R)-Cryptomerione					No. 4035
C00032253	Sugikurojin A / (+)-Sugikurojin A					No. 4912
C00032261	Sugikurojinol B / 1,8-Epoxy-1(6),2,4,7,10-bisaborapentaen-4-ol					No. 5168
C00000596	(-)-Cryptoresinol					No. 6525
C00032259	Sugikurojin J / (-)-Sugikurojin J					No. 6625
C00032260	Sugikurojinol A / (4S)-2,6,10-Bisaboratrien-4-ol-1-one					No. 6634
C00035967	7(14),10-bisaboladien-1-ol-4-one					No. 7744
C00011660	Cryptomerone					No. 7898
C00032258	Sugikurojin I / (+)-Sugikurojin I					No. 8381

Human Protein / Gene in interactions

57 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000604 C00002591 C00007204	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000604 C00002591 C00007204	0 / 1
Q02156	Protein kinase C epsilon type	Eta	C00009091 C00009092	0 / 0
P24723	Protein kinase C eta type	Eta	C00009091 C00009092	1 / 0
P05771	Protein kinase C beta type	Alpha	C00009091 C00009092	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002609 C00007203	1 / 1
P05129	Protein kinase C gamma type	Alpha	C00009091 C00009092	1 / 1
P14780	Matrix metalloproteinase-9	M10A	C00009091 C00009092	2 / 2
Q05655	Protein kinase C delta type	Delta	C00009091 C00009092	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00009091 C00009092	0 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00009091 C00009092	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002609 C00007203	1 / 1
Q04759	Protein kinase C theta type	Delta	C00009091 C00009092	0 / 1
Q05513	Protein kinase C zeta type	Iota	C00009091 C00009092	0 / 0
P47870	Gamma-aminobutyric acid receptor subunit beta-2	GABA-A beta	C00002609 C00031283	0 / 0
P14867	Gamma-aminobutyric acid receptor subunit alpha-1	GABA-A alpha	C00002609 C00031283	1 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00002609 C00031283	0 / 0
P41743	Protein kinase C iota type	Iota	C00009091 C00009092	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00007203 C00031283	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00009091 C00009092	1 / 3
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00002609 C00031283	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002609 C00031283	2 / 0
O75496	Geminin	Unclassified protein	C00002609 C00031283	0 / 0
Q15139	Serine/threonine-protein kinase D1	Pkd	C00009091 C00009092	0 / 0
Q9Y2T6	G-protein coupled receptor 55	Lysophosphatidylinositol receptor	C00002609	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00031283	7 / 3
Q9Y253	DNA polymerase eta	Enzyme	C00031283	1 / 1
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00002609	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002609	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002609	5 / 3
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00002657	1 / 1
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00002609	0 / 0
P56817	Beta-secretase 1	A1A	C00006501	0 / 0
P14902	Indoleamine 2,3-dioxygenase 1	Enzyme	C00002657	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00004653	2 / 0
P04278	Sex hormone-binding globulin	Secreted protein	C00000606	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00031283	1 / 1
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002609	2 / 2
P34972	Cannabinoid receptor 2	Cannabinoid receptor	C00002609	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002609	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002609	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00031283	0 / 0
Q9GZV3	High affinity choline transporter 1	Choline Na-symporter	C00002609	1 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00031283	1 / 0
O00255	Menin	Unclassified protein	C00002609	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002609	1 / 2
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00031283	0 / 1
P08183	Multidrug resistance protein 1	drug	C00004653	1 / 0
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00002657	1 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002609	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00002609	4 / 2
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00031283	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00002609	0 / 0
P06746	DNA polymerase beta	Enzyme	C00002609	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002609	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00004653	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00002609	0 / 0

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000604

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions