KCF-S cluster No. 335 (21 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (21)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	19
asterids	17

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Cumulative family count

class name	count
Rutaceae	19
Apiaceae	12
Asteraceae	5

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (21)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00019788	Anisocoumarin H	CHEMBL408980		10 / 6 / 3
C00019831	6,7-Di-(3,3-dimethylallyloxy)-5-hydroxycoumarin
C00019832	6,7-Di-(3,3-dimethylallyloxy)-5-methoxycoumarin
C00019891	(E)-7-(6-Hydroperoxy-3,7-dimethylocta-2,7-dienyloxy)coumarin
C00019896	7-(6R-Hydroxy-3,7-dimethylocta-2,5-dienyl)-7-hydroxycoumarin	CHEMBL2346911
C00020021	Schinilenol
C00020022	Schininallylol
C00029763	Auraptene	CHEMBL307341	C105832	28 / 25 / 26	3 / 0
C00030547	Isoschinilenol
C00033590	6-Methoxyaurapten / 7-O-Geranylscopoletin / 6-Methoxy-7-geranyloxycoumarin	CHEMBL2346913
C00033786	Diversin / Diversine
C00036626	6-Methoxy-7-geranyloxy coumarin	CHEMBL2346913
C00036786	Auraptenol
C00037062	Diversinin
C00037141	Ferulagol A
C00037142	Ferulagol B
C00039185	Excavatin A / (+)-Excavatin A
C00045665	Artekeiskeanol A	CHEMBL465504 CHEMBL454286
C00045666	Artekeiskeanol B	CHEMBL465504 CHEMBL454286
C00045667	Artekeiskeanol C	CHEMBL465505 CHEMBL465492
C00045668	Artekeiskeanol D	CHEMBL465505 CHEMBL465492

Human Protein / Gene in interactions

32 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00019788 C00029763	1 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00019788 C00029763	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00019788 C00029763	0 / 0
O75496	Geminin	Unclassified protein	C00019788 C00029763	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00019788 C00029763	2 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00019788 C00029763	2 / 2
P28482	Mitogen-activated protein kinase 1	Erk	C00029763	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00029763	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00019788	0 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00029763	1 / 4
Q9Y253	DNA polymerase eta	Enzyme	C00029763	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00029763	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00029763	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00029763	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00029763	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00029763	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00019788	0 / 0
P56817	Beta-secretase 1	A1A	C00029763	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00029763	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00029763	2 / 2
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00029763	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00029763	0 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00029763	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00029763	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00019788	0 / 0
P04062	Glucosylceramidase	Enzyme	C00029763	6 / 4
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00029763	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00029763	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00019788	1 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00029763	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00029763	1 / 4
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00029763	0 / 0

3 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00029763
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00029763
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00029763

Related Diseases

Diseases related to proteins in ChEMBL interactions