Species

KNApSAcK Entry

Organism name Luvunga sarmentosa (Bl.) Kurz.
Genus Luvunga
Family Rutaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Luvunga
Linked NCBI taxonomy ID 76969
Linked level genus

Family

Family in NCBI taxonomy Rutaceae
ID 23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (11)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003749 External link 512 Lupeol
/ Lupenol
/ (+)-Lupenol
CHEMBL289191
CHEMBL459702
C010480
3 / 0 / 0 2 / 6 No. 23 No. 51
C00023774 External link 512 Fucostanol
/ Stigmasterol
/ Dihydro-beta-sitosterol
/ (24S)24-Ethylcholestain-3beta-ol
CHEMBL66943
CHEMBL186373
CHEMBL400247
CHEMBL1568947
D013265
5 / 0 / 0 1 / 0 No. 53 No. 11
C00037864 External link 512 Suberosin
CHEMBL1928409
1 / 0 / 0 No. 466 No. 25
C00037444 External link 512 Luvungin B
/ (-)-Luvungin B
No. 1521
C00037443 External link 512 Luvungin A
/ (-)-Luvungin A
No. 1521
C00037449 External link 512 Luvungin G
/ (-)-Luvungin G
No. 1521
C00037446 External link 512 Luvungin D
/ (-)-Luvungin D
No. 1521
C00037447 External link 512 Luvungin E
/ (-)-Luvungin E
No. 1521
C00037448 External link 512 Luvungin F
/ (+)-Luvungin F
No. 1521
C00037445 External link 512 Luvungin C
No. 1521
C00002489 External link 512 Ostruthin
CHEMBL1812645
C008719
No. 1758 No. 25

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11388 DNA topoisomerase 2-alpha Isomerase C00003749 C00023774 0 / 0
P06746 DNA polymerase beta Enzyme C00023774 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00023774 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00003749 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003749 0 / 0
P56817 Beta-secretase 1 A1A C00037864 0 / 0
P09884 DNA polymerase alpha catalytic subunit Transferase C00023774 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00023774 0 / 0

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00003749
5728 PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) C00003749
10599 SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 solute carrier organic anion transporter family, member 1B1 C00023774

Related Diseases

Diseases related to CTD interactions

6 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D006528 Carcinoma, Hepatocellular C00003749
D009202 Cardiomyopathies C00003749
D006937 Hypercholesterolemia C00003749
D009374 Neoplasms, Experimental C00003749
D012878 Skin Neoplasms C00003749
D014947 Wounds and Injuries C00003749