Species

KNApSAcK Entry

Organism name Piper kadsura
Genus Piper
Family Piperaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Piper kadsura
Linked NCBI taxonomy ID 54803
Linked level species

Family

Family in NCBI taxonomy Piperaceae
ID 16739

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (13)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007212 External link 512 Galgravin
CHEMBL56800
CHEMBL57542
CHEMBL418309
CHEMBL291515
CHEMBL56856
CHEMBL56917
CHEMBL112481
CHEMBL469500
C084077
1 / 0 / 0 No. 38 No. 21
C00023774 External link 512 Fucostanol
/ Stigmasterol
/ Dihydro-beta-sitosterol
/ (24S)24-Ethylcholestain-3beta-ol
CHEMBL66943
CHEMBL186373
CHEMBL400247
CHEMBL1568947
D013265
5 / 0 / 0 1 / 0 No. 53 No. 11
C00041632 External link 512 Licarin D
No. 215 No. 23
C00041535 External link 512 Futoenone
/ (-)-Futoenone
CHEMBL295191
3 / 3 / 3 No. 1419 No. 23
C00000719 External link 512 Kadsurenone
/ Kadsurenone A
CHEMBL30122
CHEMBL296958
CHEMBL571196
CHEMBL2114380
C044540
No. 1419 No. 23
C00041404 External link 512 Burchellin
C053585
No. 1419 No. 23
C00002604 External link 512 Futoquinol
CHEMBL498296
No. 2047 No. 23
C00041766 External link 512 Piperkadsin A
/ (-)-Piperkadsin A
CHEMBL526286
No. 2047 No. 23
C00041611 External link 512 Kadsurin B
CHEMBL41463
No. 2788 No. 23
C00002610 External link 512 Kadsurin A
/ (+)-Kadsurin A
CHEMBL37432
No. 2788 No. 23
C00041633 External link 512 Liliflone
No. 2788 No. 23
C00036940 External link 512 Crotepoxide
/ (+)-Crotepoxide
CHEMBL1976475
C011828
No. 3545
C00041767 External link 512 Piperkadsin B
/ (+)-Piperkadsin B
CHEMBL498295
No. 7770

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P06746 DNA polymerase beta Enzyme C00023774 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00041535 2 / 2
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00023774 0 / 0
P03956 Interstitial collagenase M10A C00041535 0 / 1
P09884 DNA polymerase alpha catalytic subunit Transferase C00023774 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00007212 0 / 0
P08254 Stromelysin-1 M10A C00041535 1 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00023774 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00023774 0 / 0

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
10599 SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 solute carrier organic anion transporter family, member 1B1 C00023774

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#603932 Intervertebral disc disease; idd P14780
#613073 Metaphyseal anadysplasia 2; mandp2 P14780

KEGG DISEASE (3)

KEGG name UniProt
H00028 Choriocarcinoma P03956 (related)
H00025 Penile cancer P14780 (related)
H00479 Metaphyseal dysplasias P14780 (related)