Species

KNApSAcK Entry

Organism name Kalanchoe spathulata
Genus Kalanchoe
Family Crassulaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Kalanchoe
Linked NCBI taxonomy ID 23012
Linked level genus

Family

Family in NCBI taxonomy Crassulaceae
ID 3781

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005428 External link 512 Quercetin 3-glucoside-7-rhamnoside
/ Quercetin 3-O-glucoside-7-O-rhamnoside
/ Quercetin 3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside
CHEMBL592361
CHEMBL1774171
No. 1 No. 15
C00005649 External link 512 Patuletin 3,7-dirhamnoside
No. 1 No. 15
C00005140 External link 512 Afzelin
/ Kaempferol 3-O-alpha-rhamnoside
/ Kaempferol 3-O-alpha-L-rhamnopyranoside
CHEMBL240528
CHEMBL515798
C477954
4 / 2 / 2 No. 2 No. 15
C00003758 External link 512 Alnulin
/ Tiliadin
/ Skimmiol
/ Taraxerol
CHEMBL511822
CHEMBL470462
C005802
No. 13 No. 51
C00031826 External link 512 Glutinol
/ D:B-Friedoolean-5-en-3beta-ol
/ (+)-D:B-Friedoolean-5-en-3beta-ol
CHEMBL452242
No. 13 No. 51
C00003647 External link 512 Campesterol
/ 24alpha-Methylcholesterol
/ (24R)24-Methylcholest-5-en-3beta-ol
CHEMBL520535
CHEMBL485421
CHEMBL1836653
C021273
No. 53 No. 11
C00023774 External link 512 Fucostanol
/ Stigmasterol
/ Dihydro-beta-sitosterol
/ (24S)24-Ethylcholestain-3beta-ol
CHEMBL66943
CHEMBL186373
CHEMBL400247
CHEMBL1568947
D013265
5 / 0 / 0 1 / 0 No. 53 No. 11
C00003747 External link 512 Friedelin
/ Friedeline
/ Friedelanone
/ (-)-Friedelin
/ Friedelan-3-one
CHEMBL485998
CHEMBL1551590
C060796
2 / 0 / 0 No. 101 No. 52

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00005140 1 / 0
P06746 DNA polymerase beta Enzyme C00023774 0 / 0
Q8TDU6 G-protein coupled bile acid receptor 1 Steroid-like ligand receptor C00003747 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00023774 0 / 0
P16083 Ribosyldihydronicotinamide dehydrogenase [quinone] Enzyme C00005140 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00003747 0 / 0
P09884 DNA polymerase alpha catalytic subunit Transferase C00023774 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00005140 0 / 1
P98170 E3 ubiquitin-protein ligase XIAP Other cytosolic protein C00005140 1 / 1
P11388 DNA topoisomerase 2-alpha Isomerase C00023774 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00023774 0 / 0

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
10599 SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 solute carrier organic anion transporter family, member 1B1 C00023774

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#608902 Drug metabolism, poor, cyp2d6-related P10635
#300635 Lymphoproliferative syndrome, x-linked, 2; xlp2 P98170

KEGG DISEASE (2)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00107 Other well-defined immunodeficiency syndromes P98170 (related)