Eupatorium macrocephalum Lee.

• Index
• Plant Species
• Metabolite list (10)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Eupatorium macrocephalum Lee.
Genus	Eupatorium
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Eupatorium
Linked NCBI taxonomy ID	13516
Linked level	genus

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (10)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003749	Lupeol / Lupenol / (+)-Lupenol	CHEMBL289191 CHEMBL459702	C010480	3 / 0 / 0	2 / 6	No. 23	No. 51
C00003737	alpha-Amyrin / alpha-Amyrine / alpha-Amyrenol					No. 23	No. 51
C00003750	Lupeol acetate	CHEMBL453802 CHEMBL1097034	C055329	1 / 0 / 0		No. 23	No. 51
C00003738	beta-Amyrin / beta-Amirin / beta-Amyrine / beta-Amyrenol		C036380		0 / 4	No. 23	No. 51
C00023774	Fucostanol / Stigmasterol / Dihydro-beta-sitosterol / (24S)24-Ethylcholestain-3beta-ol	CHEMBL66943 CHEMBL186373 CHEMBL400247 CHEMBL1568947	D013265	5 / 0 / 0	1 / 0	No. 53	No. 11
C00023770	Sitosterol / Stigmasta-5,22-dien-3beta-ol / (24R)24-Ethylcholesta-5,22-dien-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00003673	Spinasterol / (-)-Spinasterol / alpha-Spinasterin / alpha-Spinasterol	CHEMBL487783	C031312			No. 111	No. 11
C00019308	Doursterol / Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043	C011015	5 / 4 / 2	0 / 3	No. 520
C00029508	3-O-beta-D-Glucopyranosyl-spinasterol / alpha-Spinasterol 3-O-beta-D-glucopyranoside / (-)-alpha-Spinasterol 3-O-beta-D-glucopyranoside					No. 520
C00029509	Stigmasterol-3-O-beta-D-glucopyranoside / beta-Stigmasteryl 3-O-beta-D-glucopyranoside	CHEMBL447335	C054293	2 / 0 / 0		No. 520

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003749 C00003750 C00023774	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003749 C00019308 C00023770	0 / 0
P06746	DNA polymerase beta	Enzyme	C00019308 C00023770 C00023774	0 / 0
P00734	Prothrombin	S1A	C00019308 C00023770	4 / 2
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00019308 C00023770	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00019308 C00023770	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00023770	1 / 0
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00029509	0 / 0
P08183	Multidrug resistance protein 1	drug	C00023770	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00023770	0 / 1
P11387	DNA topoisomerase 1	Isomerase	C00003749	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00023770	3 / 2
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00023774	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00023770	2 / 0
P14679	Tyrosinase	Oxidoreductase	C00023770	4 / 2
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00029509	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00023770	0 / 0
P03372	Estrogen receptor	NR3A1	C00023770	1 / 1
P09884	DNA polymerase alpha catalytic subunit	Transferase	C00023774	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00023770	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00023770	0 / 1
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00023770	1 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00023770	1 / 1
Q02880	DNA topoisomerase 2-beta	Isomerase	C00023774	0 / 0

3 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00003749
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00003749
10599	SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6	solute carrier organic anion transporter family, member 1B1	C00023774

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions