| Organism name | Citrus unshiu |
|---|---|
| Genus | Citrus |
| Family | Rutaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Citrus unshiu |
|---|---|
| Linked NCBI taxonomy ID | 55188 |
| Linked level | species |
| Family in NCBI taxonomy | Rutaceae |
|---|---|
| ID | 23513 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00006232
|
3,6-Di-C-glucosylapigenin
|
No. 1 | No. 15 |
|
||||
|
C00005715
|
Limocitrin 3-glucoside
/ Limocitrin 3-O-beta-glucopyranoside / Limocitrin 3-O-beta-D-glucopyranoside |
No. 2 | No. 15 |
|
||||
|
C00005716
|
Limocitrin 3-rhamnoside
|
No. 2 | No. 15 |
|
||||
|
C00000009
|
GA9
/ Gibberellin A9 |
No. 40 | No. 41 |
|
||||
|
C00000008
|
GA8
/ Gibberellin A8 |
No. 40 | No. 41 |
|
||||
|
C00000004
|
GA4
/ Gibberellin A4 |
No. 40 | No. 41 |
|
||||
|
C00000020
|
GA20
/ Gibberellin A20 |
No. 40 | No. 41 |
|
||||
|
C00000029
|
GA29
/ Gibberellin A29 |
No. 40 | No. 41 |
|
||||
|
C00000044
|
GA44
/ Gibberellin A44 |
No. 40 | No. 41 |
|
||||
|
C00000001
|
GA1
/ Gibberellin A1 |
C422660
|
No. 40 | No. 41 |
|
|||
|
C00000987
|
Neohesperidin
|
CHEMBL506398
CHEMBL1885559 |
1 / 0 / 0 | No. 48 | No. 14 |
|
||
|
C00000017
|
GA17
/ Gibberellin A17 |
No. 187 | No. 41 |
|
||||
|
C00000024
|
GA24
/ Gibberellin A24 |
C120176
|
No. 187 | No. 41 |
|
|||
|
C00000019
|
GA19
/ Gibberellin A19 |
C120175
|
No. 187 | No. 41 |
|
|||
|
C00000025
|
GA25
/ Gibberellin A25 |
No. 187 | No. 41 |
|
||||
|
C00000053
|
GA53
/ Gibberellin A53 |
No. 187 | No. 41 |
|
||||
|
C00000805
|
alpha-Pinene
|
CHEMBL442565
|
C005451
|
3 / 3 / 2 | 0 / 1 | No. 476 | No. 35 |
|
|
C00000108
|
IAM
/ Indole-3-acetamide / 1H-Indole-3-acetamide |
C015950
|
No. 710 | No. 4 |
|
|||
|
C00000803
|
(-)-Limonene
|
CHEMBL15799
CHEMBL449062 |
7 / 21 / 48 | No. 848 | No. 35 |
|
||
|
C00000100
|
IAA
/ Indole-3-acetic acid |
CHEMBL82411
|
C030737
|
3 / 0 / 0 | 2 / 1 | No. 1432 | No. 4 |
|
|
C00000848
|
Isopentenyl diphosphate
|
CHEMBL356362
|
C004809
|
7 / 2 | No. 3297 |
|
||
|
C00000846
|
Geranyl diphosphate
/ Geranyl pyrophosphate |
CHEMBL41342
|
C015234
|
1 / 0 / 0 | 2 / 0 | No. 3475 | No. 34 |
|
|
C00000101
|
IAA methyl ester
/ Methyl indole-3-acetate |
No. 4225 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00000803 | 7 / 37 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000803 | 0 / 3 |
| Q16773 | Kynurenine--oxoglutarate transaminase 1 | Enzyme | C00000100 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00000803 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000803 | 11 / 10 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000805 | 3 / 2 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000803 | 3 / 1 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00000803 | 0 / 0 |
| P02768 | Serum albumin | Secreted protein | C00000100 | 0 / 0 |
| P14324 | Farnesyl pyrophosphate synthase | Transferase | C00000846 | 0 / 0 |
| Q9HBH1 | Peptide deformylase, mitochondrial | Enzyme | C00000100 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000805 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00000805 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000803 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000987 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1234 | CCR5, CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
C00000848
|
| 2224 | FDPS, FPPS, FPS | farnesyl diphosphate synthase (EC:2.5.1.1 2.5.1.10) |
C00000848
|
| 2254 | FGF9, FGF-9, GAF, HBFG-9, HBGF-9, SYNS3 | fibroblast growth factor 9 |
C00000848
|
| 3458 | IFNG, IFG, IFI | interferon, gamma |
C00000848
|
| 3559 | IL2RA, CD25, IDDM10, IL2R, TCGFR | interleukin 2 receptor, alpha |
C00000848
|
| 162514 | TRPV3, OLMS, VRL3 | transient receptor potential cation channel, subfamily V, member 3 |
C00000848
|
| 7421 | VDR, NR1I1 | vitamin D (1,25- dihydroxyvitamin D3) receptor |
C00000848
|
| 3156 | HMGCR, LDLCQ3 | 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) |
C00000846
|
| 5906 | RAP1A, KREV-1, KREV1, RAP1, SMGP21 | RAP1A, member of RAS oncogene family |
C00000846
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000100
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00000100
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #211980 | Lung cancer |
P04637
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P35354 (related) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
|
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
P35354 (related) |
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|