PCIDB

KNApSAcK Metabolite C00000848

Metabolite

KNApSAcK Entry

id C00000848
Name Isopentenyl diphosphate
CAS RN 358-71-4
Standard InChI InChI=1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h1,3-4H2,2H3,(H,9,10)(H2,6,7,8)
Standard InChI (Main Layer) InChI=1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h1,3-4H2,2H3,(H,9,10)(H2,6,7,8)

Cluster

Phytochemical cluster
KCF-S cluster No. 3297

Link

ChEMBL

By standard InChI CHEMBL356362
By standard InChI Main Layer CHEMBL356362

KEGG

By LinkDB C00129

CTD

By CAS RN C004809

Human Protein / Gene in interaction

CTD interaction (13)

compound gene gene name gene description interaction interaction type form reference
pmid
C004809 1234 CCR5
CC-CKR-5
CCCKR5
CCR-5
CD195
CKR-5
CKR5
CMKBR5
IDDM22
chemokine (C-C motif) receptor 5 (gene/pseudogene) isopentenyl pyrophosphate results in decreased expression of CCR5 protein decreases expression
protein 11994442
C004809 2224 FDPS
FPPS
FPS
farnesyl diphosphate synthase (EC:2.5.1.1 2.5.1.10) [zoledronic acid results in decreased activity of FDPS protein] which results in increased abundance of isopentenyl pyrophosphate decreases activity
/ increases abundance
protein 19699819
C004809 2254 FGF9
FGF-9
GAF
HBFG-9
HBGF-9
SYNS3
fibroblast growth factor 9 isopentenyl pyrophosphate results in increased expression of FGF9 mRNA increases expression
mRNA 14704367
C004809 2254 FGF9
FGF-9
GAF
HBFG-9
HBGF-9
SYNS3
fibroblast growth factor 9 isopentenyl pyrophosphate results in increased expression of FGF9 protein increases expression
protein 14704367
C004809 3458 IFNG
IFG
IFI
interferon, gamma Calcitriol inhibits the reaction [isopentenyl pyrophosphate results in increased expression of IFNG protein] decreases reaction
/ increases expression
protein 15879110
C004809 3458 IFNG
IFG
IFI
interferon, gamma isopentenyl pyrophosphate results in increased expression of IFNG protein increases expression
protein 15879110
C004809 3559 IL2RA
CD25
IDDM10
IL2R
TCGFR
interleukin 2 receptor, alpha Calcitriol inhibits the reaction [isopentenyl pyrophosphate results in increased expression of IL2RA protein] decreases reaction
/ increases expression
protein 15879110
C004809 3559 IL2RA
CD25
IDDM10
IL2R
TCGFR
interleukin 2 receptor, alpha isopentenyl pyrophosphate results in increased expression of IL2RA protein increases expression
protein 15879110
C004809 162514 TRPV3
OLMS
VRL3
transient receptor potential cation channel, subfamily V, member 3 isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein] decreases reaction
/ increases activity
protein 21353389
C004809 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein] decreases reaction
/ increases expression
protein 15879110
C004809 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor Go 6976 inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein] decreases reaction
/ increases expression
protein 15879110
C004809 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor isopentenyl pyrophosphate results in increased expression of VDR protein increases expression
protein 15879110
C004809 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor U 0126 inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein] decreases reaction
/ increases expression
protein 15879110

Related Disease

Diseases related to CTD interactions

2 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D006930 C004809 Hyperalgesia therapeutic
21353389
D010146 C004809 Pain therapeutic
21353389