PCIDB

Prunus cerasus

Species

KNApSAcK Entry

Organism name Prunus cerasus
Genus Prunus
Family Rosaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Prunus cerasus
Linked NCBI taxonomy ID 140311
Linked level species

Family

Family in NCBI taxonomy Rosaceae
ID 3745

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Natural Activity

List (12)

Species Activity
Prunus cerasus L. Analgesic
Prunus cerasus L. Anticancer
Prunus cerasus L. Antiinflammatory
Prunus cerasus L. Antioxidant
Prunus cerasus L. Antipyretic
Prunus cerasus L. Apoptotic
Prunus cerasus L. Astringent
Prunus cerasus L. Diuretic
Prunus cerasus L. Hematonic
Prunus cerasus L. Pectoral
Prunus cerasus L. Sedative
Prunus cerasus L. Tonic

Metabolite list (31)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00002376 External link 512 Cyanidin 3-rutinoside
CHEMBL505251
C020386
3 / 0 / 1 No. 1 No. 15
C00005194 External link 512 Kaempferol 3,4'-diglucoside
/ Kaempferol 3,4'-di-O-beta-D-glucopyranoside
/ 3-(beta-D-Glucopyranosyloxy)-2-[4-(beta-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
CHEMBL2206208
No. 1 No. 15
C00006658 External link 512 Cyanidin 3-sophoroside
No. 1 No. 15
C00006660 External link 512 Cyanidin 3-gentiobioside
No. 1 No. 15
C00006680 External link 512 Peonidin galactoside
/ Peonidin 3-galactoside
/ Peonidin 3-O-beta-D-galactopyranoside
CHEMBL1784263
No. 2 No. 15
C00010162 External link 512 Genistein 5-O-glucoside
No. 2 No. 15
C00010167 External link 512 Prunetinoside
/ Prunetin 5-O-glucoside
No. 2 No. 15
C00002374 External link 512 Chrysanthemin
/ Cyanidin 3-O-glucoside
CHEMBL257839
CHEMBL1197952
C114438
1 / 0 / 1 No. 2 No. 15
C00013313 External link 512 Isothymusin
/ 5,8-Dihydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one
CHEMBL487196
C487424
1 / 0 / 0 No. 3 No. 15
C00006671 External link 512 Cyanidin 3-(2G-xylosylrutinoside)
No. 5 No. 15
C00005488 External link 512 Quercetin 3-rutinoside-7,3'-diglucoside
No. 5 No. 15
C00008157 External link 512 Dihydrowogonin 7-O-glucoside
No. 12 No. 14
C00008156 External link 512 Dihydrowogonin
No. 25 No. 14
C00000087 External link 512 GA87
/ Gibberellin A87
No. 40 No. 41
C00000295 External link 512 GA95
/ Gibberellin A95
No. 40 No. 41
C00000086 External link 512 GA86
/ Gibberellin A86
No. 40 No. 41
C00000044 External link 512 GA44
/ Gibberellin A44
No. 40 No. 41
C00000020 External link 512 GA20
/ Gibberellin A20
No. 40 No. 41
C00000032 External link 512 GA32
/ Gibberellin A32
No. 40 No. 41
C00000030 External link 512 GA30
/ Gibberellin A30
No. 40 No. 41
C00000003 External link 512 GA3
/ Gibberellin A3
CHEMBL513241
CHEMBL566653
CHEMBL1232952
CHEMBL1476967
CHEMBL1487394
C007842
10 / 18 / 17 No. 40 No. 41
C00008557 External link 512 Aromadendrin 4'-methyl ether
CHEMBL480655
CHEMBL458480
No. 42 No. 14
C00008355 External link 512 Cerasinone
No. 77 No. 14
C00006965 External link 512 Cerasin
CHEMBL601679
No. 79
C00006966 External link 512 Cerasidin
No. 79
C00000025 External link 512 GA25
/ Gibberellin A25
No. 187 No. 41
C00000019 External link 512 GA19
/ Gibberellin A19
C120175
No. 187 No. 41
C00000096 External link 512 9-Ribosyl-trans-zeatin
/ Zeatin-9-beta-D-ribofuranoside
No. 989
C00000100 External link 512 IAA
/ Indole-3-acetic acid
CHEMBL82411
C030737
3 / 0 / 0 2 / 1 No. 1432 No. 4
C00000091 External link 512 trans-Zeatin
CHEMBL525239
D015026
2 / 3 / 2 0 / 1 No. 2879
C00000101 External link 512 IAA methyl ester
/ Methyl indole-3-acetate
No. 4225

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000003 1 / 0
Q16773 Kynurenine--oxoglutarate transaminase 1 Enzyme C00000100 0 / 0
P28907 ADP-ribosyl cyclase 1 Enzyme C00002374 0 / 1
Q07812 Apoptosis regulator BAX Unclassified protein C00002376 0 / 1
P02545 Prelamin-A/C Unclassified protein C00000003 11 / 10
P16473 Thyrotropin receptor Glycohormone receptor C00000091 3 / 2
P02768 Serum albumin Secreted protein C00000100 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000003 0 / 1
P15559 NAD(P)H dehydrogenase [quinone] 1 Enzyme C00013313 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000003 2 / 0
O75496 Geminin Unclassified protein C00000003 0 / 0
Q16611 Bcl-2 homologous antagonist/killer Unclassified protein C00002376 0 / 0
O43521 Bcl-2-like protein 11 Unclassified protein C00002376 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00000003 0 / 0
Q9HBH1 Peptide deformylase, mitochondrial Enzyme C00000100 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000003 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000003 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000003 0 / 1
P10275 Androgen receptor NR3C4 C00000003 3 / 4
P46063 ATP-dependent DNA helicase Q1 Enzyme C00000091 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
196 AHR, bHLHe76 aryl hydrocarbon receptor C00000100
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00000100

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (21)

OMIM preferred title UniProt
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275

KEGG DISEASE (21)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00005 Chronic lymphocytic leukemia (CLL) P28907 (marker)
H01171 Poor drug metabolism (PM) P33261 (related)
H00020 Colorectal cancer Q07812 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D056486 Drug-Induced Liver Injury C00000100
D000647 Amnesia C00000091