PCIDB

KNApSAcK Metabolite C00000003

Metabolite

KNApSAcK Entry

id C00000003
Name GA3 / Gibberellin A3
CAS RN 77-06-5
Standard InChI InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10-,11+,12-,13-,16-,17+,18+,19-/m1/s1
Standard InChI (Main Layer) InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)

Cluster

Phytochemical cluster No. 41
KCF-S cluster No. 40

Link

ChEMBL

By standard InChI CHEMBL1232952
By standard InChI Main Layer CHEMBL513241 CHEMBL566653 CHEMBL1232952 CHEMBL1476967 CHEMBL1487394

KEGG

By LinkDB C01699

CTD

By CAS RN C007842

Species

Summary

Plant class

class name count
rosids 32
asterids 9
Liliopsida 8
Spermatophyta 4

Family (Top 10)

family name count
Fabaceae 9
Poaceae 8
Rosaceae 6
Convolvulaceae 6
Cucurbitaceae 4
Pinaceae 4
Malvaceae 3
Brassicaceae 3
Rhodospirillaceae 2
Nectriaceae 2

List (61)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Abelmoschus esculentus 455045 Malvaceae rosids Viridiplantae
Althaea rosea 1219290 Malvaceae rosids Viridiplantae
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Avena sativa 4498 Poaceae Liliopsida Viridiplantae
Azospirillum brasilense 192 Rhodospirillaceae Bacteria
Azospirillum lipoferum 193 Rhodospirillaceae Bacteria
Bacillus licheniformis 1402 Bacillaceae Bacteria
Bacillus pumilus 1408 Bacillaceae Bacteria
Brassica campestris 145471 Brassicaceae rosids Viridiplantae
Brassica napus 3708 Brassicaceae rosids Viridiplantae
Bruguiera gymnorrhiza 39984 Rhizophoraceae rosids Viridiplantae
Calystegia soldanella 136204 Convolvulaceae asterids Viridiplantae
Camellia sinensis 4442 Theaceae asterids Viridiplantae
Carica papaya 3649 Caricaceae rosids Viridiplantae
Carthamus tinctorius 4222 Asteraceae asterids Viridiplantae
Cassia fistula 53852 Fabaceae rosids Viridiplantae
Citrus sinensis 2711 Rutaceae rosids Viridiplantae
Cucumis melo 3656 Cucurbitaceae rosids Viridiplantae
Cucumis sativus 3659 Cucurbitaceae rosids Viridiplantae
Dalbergia dolichopetala 53862 Fabaceae rosids Viridiplantae
Fragaria x ananassa 3747 Rosaceae rosids Viridiplantae
Fusarium fujikuroi 5127 Nectriaceae Fungi
Gibberella fujikuroi 5127 Nectriaceae Fungi
Gluconacetobacter diazotrophicus 33996 Acetobacteraceae Bacteria
Gossypium hirsutum 3635 Malvaceae rosids Viridiplantae
Herbaspirillum seropedicae 964 Oxalobacteraceae Bacteria
Hordeum vulgare 4513 Poaceae Liliopsida Viridiplantae
Ipomoea batatas 4120 Convolvulaceae asterids Viridiplantae
Ipomoea reptans 4119 Convolvulaceae asterids Viridiplantae
Ipomoea tricolor 89664 Convolvulaceae asterids Viridiplantae
Lactuca sativa 4236 Asteraceae asterids Viridiplantae
Lolium temulentum 34176 Poaceae Liliopsida Viridiplantae
Lupinus albus 3870 Fabaceae rosids Viridiplantae
Malus domestica 3750 Rosaceae rosids Viridiplantae
Mangifera indica 29780 Anacardiaceae rosids Viridiplantae
Marah macrocarpus 48242 Cucurbitaceae rosids Viridiplantae
Pennisetum glaucum 4543 Poaceae Liliopsida Viridiplantae
Pharbitis purpurea 4119 Convolvulaceae asterids Viridiplantae
Phaseolus coccineus 3886 Fabaceae rosids Viridiplantae
Phaseolus lunatus 3884 Fabaceae rosids Viridiplantae
Phaseolus multiflorus 3886 Fabaceae rosids Viridiplantae
Picea abies 3329 Pinaceae Spermatophyta Viridiplantae
Pinus attenuata 71624 Pinaceae Spermatophyta Viridiplantae
Pinus sylvestris 3349 Pinaceae Spermatophyta Viridiplantae
Pisum sativum 3888 Fabaceae rosids Viridiplantae
Prunus avium 42229 Rosaceae rosids Viridiplantae
Prunus cerasus 140311 Rosaceae rosids Viridiplantae
Prunus persica 3760 Rosaceae rosids Viridiplantae
Pseudotsuga menziesii 3357 Pinaceae Spermatophyta Viridiplantae
Pyrus communis 23211 Rosaceae rosids Viridiplantae
Quamoclit pennata 4118 Convolvulaceae asterids Viridiplantae
Rhizophora mucronata 61149 Rhizophoraceae rosids Viridiplantae
Saccharum spp. 4546 Poaceae Liliopsida Viridiplantae
Secale cereale 4550 Poaceae Liliopsida Viridiplantae
Sechium edule 184140 Cucurbitaceae rosids Viridiplantae
Senna tora 362788 Fabaceae rosids Viridiplantae
Sonneratia apetala 122813 Lythraceae rosids Viridiplantae
Triticum aestivum 4565 Poaceae Liliopsida Viridiplantae
Vigna unguiculata 3917 Fabaceae rosids Viridiplantae
Vitis vinifera 29760 Vitaceae rosids Viridiplantae
Zea mays 4577 Poaceae Liliopsida Viridiplantae

Human Protein / Gene in interaction

10 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1487394 CHEMBL1741321 (1)
1 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL1487394 CHEMBL1614544 (1)
11 / 10
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1487394 CHEMBL1741325 (1)
0 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL1232952 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL1232952 CHEMBL2114780 (1)
0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1232952 CHEMBL1794401 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL1487394 CHEMBL1741322 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1487394 CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1487394 CHEMBL1741324 (1)
0 / 1
P10275 Androgen receptor NR3C4 CHEMBL1232952 CHEMBL1794560 (1)
3 / 4

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275

KEGG DISEASE (17)

KEGG disease name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)