Triticum aestivum
Species
KNApSAcK Entry
| Organism name | Triticum aestivum |
|---|---|
| Genus | Triticum |
| Family | Poaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Triticum aestivum |
|---|---|
| Linked NCBI taxonomy ID | 4565 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Poaceae |
|---|---|
| ID | 4479 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Metabolite list (48)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006686
|
Peonidin 3-rutinoside
|
No. 1 | No. 15 |
|
||||
|
C00006276
|
Isoswertisin 4'-O-glucoside
|
No. 1 | No. 15 |
|
||||
|
C00006206
|
Lutonarin
|
CHEMBL470327
|
No. 1 | No. 15 |
|
|||
|
C00006229
|
Vicenin 2
/ Apigenin 6,8-di-C-glucoside |
CHEMBL1442950
|
6 / 14 / 8 | No. 1 | No. 15 |
|
||
|
C00002374
|
Chrysanthemin
/ Cyanidin 3-O-glucoside |
CHEMBL257839
CHEMBL1197952 |
C114438
|
1 / 0 / 1 | No. 2 | No. 15 |
|
|
|
C00006681
|
Oxycoccicyanin
/ Peonidin 3-O-beta-D-glucopyranoside |
CHEMBL1784263
|
No. 2 | No. 15 |
|
|||
|
C00006315
|
Wyomin
|
No. 5 | No. 15 |
|
||||
|
C00000044
|
GA44
/ Gibberellin A44 |
No. 40 | No. 41 |
|
||||
|
C00000009
|
GA9
/ Gibberellin A9 |
No. 40 | No. 41 |
|
||||
|
C00000020
|
GA20
/ Gibberellin A20 |
No. 40 | No. 41 |
|
||||
|
C00000008
|
GA8
/ Gibberellin A8 |
No. 40 | No. 41 |
|
||||
|
C00000007
|
GA7
/ Gibberellin A7 |
No. 40 | No. 41 |
|
||||
|
C00000029
|
GA29
/ Gibberellin A29 |
No. 40 | No. 41 |
|
||||
|
C00000034
|
GA34
/ Gibberellin A34 |
No. 40 | No. 41 |
|
||||
|
C00000015
|
GA15
/ Gibberellin A15 |
No. 40 | No. 41 |
|
||||
|
C00000004
|
GA4
/ Gibberellin A4 |
No. 40 | No. 41 |
|
||||
|
C00000054
|
GA54
/ Gibberellin A54 |
No. 40 | No. 41 |
|
||||
|
C00000055
|
GA55
/ Gibberellin A55 |
No. 40 | No. 41 |
|
||||
|
C00000060
|
GA60
/ Gibberellin A60 |
No. 40 | No. 41 |
|
||||
|
C00000061
|
GA61
/ Gibberellin A61 |
No. 40 | No. 41 |
|
||||
|
C00000062
|
GA62
/ Gibberellin A62 |
No. 40 | No. 41 |
|
||||
|
C00000079
|
GA79
/ Gibberellin A79 |
No. 40 | No. 41 |
|
||||
|
C00000090
|
GA90
/ Gibberellin A90 |
No. 40 | No. 41 |
|
||||
|
C00000003
|
GA3
/ Gibberellin A3 |
CHEMBL513241
CHEMBL566653 CHEMBL1232952 CHEMBL1476967 CHEMBL1487394 |
C007842
|
10 / 18 / 17 | No. 40 | No. 41 |
|
|
|
C00000224
|
GA92
/ Gibberellin A92 |
No. 40 | No. 41 |
|
||||
|
C00000299
|
GA98
/ Gibberellin A98 |
No. 40 | No. 41 |
|
||||
|
C00000294
|
GA94
/ Gibberellin A94 |
No. 40 | No. 41 |
|
||||
|
C00000228
|
GA93
/ Gibberellin A93 |
No. 40 | No. 41 |
|
||||
|
C00000216
|
GA91
/ Gibberellin A91 |
No. 40 | No. 41 |
|
||||
|
C00000001
|
GA1
/ Gibberellin A1 |
C422660
|
No. 40 | No. 41 |
|
|||
|
C00001263
|
Octacosan-1-ol
|
CHEMBL1951714
|
C044309
|
No. 115 |
|
|||
|
C00001251
|
Hentriacontane-14,16-dione
|
No. 115 |
|
|||||
|
C00000019
|
GA19
/ Gibberellin A19 |
C120175
|
No. 187 | No. 41 |
|
|||
|
C00000298
|
GA97
/ Gibberellin A97 |
No. 187 | No. 41 |
|
||||
|
C00000017
|
GA17
/ Gibberellin A17 |
No. 187 | No. 41 |
|
||||
|
C00000025
|
GA25
/ Gibberellin A25 |
No. 187 | No. 41 |
|
||||
|
C00000053
|
GA53
/ Gibberellin A53 |
No. 187 | No. 41 |
|
||||
|
C00000024
|
GA24
/ Gibberellin A24 |
C120176
|
No. 187 | No. 41 |
|
|||
|
C00000218
|
Jasmonic acid
/ trans-Jasmonic acid / 3-Oxo-2-(2Z-pentenyl)cyclotentylacetic acid |
CHEMBL445499
CHEMBL449572 |
C011006
|
4 / 1 / 0 | No. 707 | No. 70 |
|
|
|
C00000446
|
7-iso-Jasmonic acid
/ (+)-Epijasmonic acid |
CHEMBL445499
CHEMBL449572 |
4 / 1 / 0 | No. 707 | No. 70 |
|
||
|
C00000366
|
OPC-8:0
/ 3-Oxo-2-(2-entenyl)cyclopentaneoctanoic acid |
No. 707 | No. 70 |
|
||||
|
C00000361
|
OPC-4:0
|
No. 707 | No. 70 |
|
||||
|
C00000099
|
2-Methylthioribosylzeatin
/ trans-Methylthioribosylzeatin / 2-Methylthioribosyl-trans-zeatin |
No. 989 |
|
|||||
|
C00000096
|
9-Ribosyl-trans-zeatin
/ Zeatin-9-beta-D-ribofuranoside |
No. 989 |
|
|||||
|
C00000134
|
(s)-(+)-Abscisic acid
/ 2,4-Pentadienoic acid |
CHEMBL288040
CHEMBL379808 CHEMBL1318134 CHEMBL1469719 CHEMBL1741460 CHEMBL1965138 |
D000040
|
10 / 9 / 10 | No. 1435 | No. 38 |
|
|
|
C00000091
|
trans-Zeatin
|
CHEMBL525239
|
D015026
|
2 / 3 / 2 | 0 / 1 | No. 2879 |
|
|
|
C00000094
|
2iP
/ N6-(delta2-Isopentenyl)adenine |
CHEMBL476189
|
C001478
|
5 / 2 / 3 | 18 / 0 | No. 2879 |
|
|
|
C00001538
|
DIMBOA glucoside
|
CHEMBL519905
|
No. 4800 |
|
Human Protein / Gene in interactions
26 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000003 C00000094 C00000134 | 1 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000003 C00000094 C00000134 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000003 C00000094 C00000134 | 0 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000003 C00000094 C00000134 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000003 C00000094 C00000134 | 1 / 1 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000218 C00000446 | 1 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000091 C00000134 | 3 / 2 |
| P10275 | Androgen receptor | NR3C4 | C00000003 C00000134 | 3 / 4 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000218 C00000446 | 0 / 0 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000218 C00000446 | 0 / 0 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000218 C00000446 | 1 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000003 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00006229 | 7 / 3 |
| P10145 | Interleukin-8 | Secreted protein | C00000134 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000003 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000003 | 2 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000134 | 1 / 1 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000003 | 11 / 10 |
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00002374 | 0 / 1 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00006229 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00006229 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000134 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00006229 | 6 / 4 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00006229 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000091 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00006229 | 0 / 0 |
18 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 440 | ASNS, TS11 | asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) |
C00000094
|
| 694 | BTG1 | B-cell translocation gene 1, anti-proliferative |
C00000094
|
| 10681 | GNB5, GB5 | guanine nucleotide binding protein (G protein), beta 5 |
C00000094
|
| 182 | JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1 | jagged 1 |
C00000094
|
| 9818 | NUPL1, PRO2463 | nucleoporin like 1 |
C00000094
|
| 5142 | PDE4B, DPDE4, PDE4B5, PDEIVB | phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17) |
C00000094
|
| 8544 | PIR | pirin (iron-binding nuclear protein) (EC:1.13.11.24) |
C00000094
|
| 5366 | PMAIP1, APR, NOXA | phorbol-12-myristate-13-acetate-induced protein 1 |
C00000094
|
| 9360 | PPIG, CARS-Cyp, CYP, SCAF10, SRCyp | peptidylprolyl isomerase G (cyclophilin G) (EC:5.2.1.8) |
C00000094
|
| 5782 | PTPN12, PTP-PEST, PTPG1 | protein tyrosine phosphatase, non-receptor type 12 (EC:3.1.3.48) |
C00000094
|
| 5774 | PTPN3, PTP-H1, PTPH1 | protein tyrosine phosphatase, non-receptor type 3 (EC:3.1.3.48) |
C00000094
|
| 6004 | RGS16, A28-RGS14, A28-RGS14P, RGS-R | regulator of G-protein signaling 16 |
C00000094
|
| 6016 | RIT1, NS8, RIBB, RIT, ROC1 | Ras-like without CAAX 1 |
C00000094
|
| 6286 | S100P, MIG9 | S100 calcium binding protein P |
C00000094
|
| 7029 | TFDP2, DP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
C00000094
|
| 7127 | TNFAIP2, B94, EXOC3L3 | tumor necrosis factor, alpha-induced protein 2 |
C00000094
|
| 7296 | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR | thioredoxin reductase 1 (EC:1.8.1.9) |
C00000094
|
| 7431 | VIM, CTRCT30 | vimentin |
C00000094
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (37)
| OMIM | preferred title | UniProt |
|---|---|---|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
KEGG DISEASE (29)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P28907
(marker)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|