Pyrus communis

• Index
• Plant Species
• Natural Activity
• Metabolite list (20)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Pyrus communis
Genus	Pyrus
Family	Rosaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Pyrus communis
Linked NCBI taxonomy ID	23211
Linked level	species

Family

Family in NCBI taxonomy	Rosaceae
ID	3745

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Natural Activity

List (7)

Species	Activity
Pyrus communis L.	Antibacterial
Pyrus communis L.	Antipyretic
Pyrus communis L.	Antiseptic
Pyrus communis L.	Aphrodisiac
Pyrus communis L.	Astringent
Pyrus communis L.	Diuretic
Pyrus communis L.	Laxative

Metabolite list (20)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005538	Isorhamnetin 3-robinobioside / Isorhamnetin 3-O-robinobioside	CHEMBL84174 CHEMBL258394 CHEMBL1711509 CHEMBL2165403		7 / 1 / 2		No. 1	No. 15
C00005956	Quercetin 3-O-malonylglucoside / Quercetin 3-(6''-malonylglucoside) / Quercetin 3-O-(6''-O-malonyl)-beta-D-glucoside					No. 2	No. 15
C00006006	Isorhamnetin 3-(6''-malonylglucoside)					No. 2	No. 15
C00005844	Kaempferol 3-(6''-malonylglucoside)					No. 2	No. 15
C00006652	Idaein / Cyanidin 3-galactoside / Cyanidin 3-O-galactoside / Cyanidin 3-O-beta-D-galactopyranoside	CHEMBL257839 CHEMBL1197952		1 / 0 / 1		No. 2	No. 15
C00005607	Rhamnazin 3-glucoside	CHEMBL563399				No. 2	No. 15
C00002407	beta-Pyrufuran					No. 3	No. 15
C00002396	2,8-Dihydroxy-3,4,7-trimethoxy-dibenzofuran					No. 3	No. 15
C00002406	alpha-Pyrufuran					No. 3	No. 15
C00000003	GA3 / Gibberellin A3	CHEMBL513241 CHEMBL566653 CHEMBL1232952 CHEMBL1476967 CHEMBL1487394	C007842	10 / 18 / 17		No. 40	No. 41
C00000045	GA45 / Gibberellin A45					No. 40	No. 41
C00000063	GA63 / Gibberellin A63					No. 40	No. 41
C00000068	GA68 / Gibberellin A68					No. 40	No. 41
C00002638	Arbutin	CHEMBL226495 CHEMBL232202 CHEMBL1357990	D001104	5 / 7 / 5	282 / 0	No. 45	No. 72
C00000025	GA25 / Gibberellin A25					No. 187	No. 41
C00000017	GA17 / Gibberellin A17					No. 187	No. 41
C00000096	9-Ribosyl-trans-zeatin / Zeatin-9-beta-D-ribofuranoside					No. 989
C00002656	Hydroquinone / 1,4-Benzenediol	CHEMBL537	C031927	55 / 48 / 51	156 / 14	No. 1590	No. 82
C00000091	trans-Zeatin	CHEMBL525239	D015026	2 / 3 / 2	0 / 1	No. 2879
C00001309	Ethyl (E,Z)-decadienoate					No. 5017

Human Protein / Gene in interactions

67 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000003 C00002656 C00005538	0 / 1
O75496	Geminin	Unclassified protein	C00000003 C00002656 C00005538	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002638 C00002656	0 / 3
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002638 C00002656	0 / 0
P03372	Estrogen receptor	NR3A1	C00002656 C00005538	1 / 1
P10275	Androgen receptor	NR3C4	C00000003 C00002656	3 / 4
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002656 C00005538	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000003 C00002656	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000091 C00002656	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000003 C00002638	2 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000003 C00002656	11 / 10
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000003	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002656	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000091	3 / 2
P10828	Thyroid hormone receptor beta	NR1A2	C00002656	3 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002656	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00002656	1 / 2
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000003	0 / 1
P07237	Protein disulfide-isomerase	Enzyme	C00005538	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00002656	1 / 2
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00002656	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00002656	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00002656	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002656	0 / 0
P68871	Hemoglobin subunit beta	Secreted protein	C00002656	4 / 4
O43570	Carbonic anhydrase 12	Lyase	C00002656	1 / 2
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002656	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002656	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00002656	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002656	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002656	0 / 0
P10145	Interleukin-8	Secreted protein	C00002656	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002656	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00005538	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00002656	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00002656	0 / 1
P14679	Tyrosinase	Oxidoreductase	C00002638	4 / 2
Q96RI1	Bile acid receptor	NR1H4	C00002656	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000003	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002656	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002656	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002656	2 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002656	1 / 1
Q01453	Peripheral myelin protein 22	Unclassified protein	C00002656	5 / 2
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00002656	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00002656	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002656	2 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00002656	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002656	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00006652	0 / 1
Q99700	Ataxin-2	Unclassified protein	C00002656	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00005538	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002656	4 / 3
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00002656	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002656	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002656	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00002656	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00002656	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00002656	1 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002656	0 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00002656	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00002656	1 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002656	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002638	1 / 0
O00255	Menin	Unclassified protein	C00002656	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002656	1 / 2
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000003	1 / 0

437 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00002638 C00002656
6571	SLC18A2, SVAT, SVMT, VAT2, VMAT2	solute carrier family 18 (vesicular monoamine transporter), member 2	C00002638
396	ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1	Rho GDP dissociation inhibitor (GDI) alpha	C00002656
468	ATF4, CREB-2, CREB2, TAXREB67, TXREB	activating transcription factor 4	C00002656
572	BAD, BBC2, BCL2L8	BCL2-associated agonist of cell death	C00002656
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00002656
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00002656
664	BNIP3, NIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	C00002656
79866	BORA, C13orf34	bora, aurora kinase A activator	C00002656
7832	BTG2, PC3, TIS21	BTG family, member 2	C00002656
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002656
839	CASP6, MCH2	caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59)	C00002656
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00002656
64782	AEN, ISG20L1, pp12744	apoptosis enhancing nuclease	C00002656
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00002656
847	CAT	catalase (EC:1.11.1.6)	C00002656
6356	CCL11, SCYA11	chemokine (C-C motif) ligand 11	C00002656
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00002656
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00002656
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00002656
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00002656
9134	CCNE2, CYCE2	cyclin E2	C00002656
899	CCNF, FBX1, FBXO1	cyclin F	C00002656
942	CD86, B7-2, B7.2, B70, CD28LG2, LAB72	CD86 molecule	C00002656
157313	CDCA2, Repo-Man	cell division cycle associated 2	C00002656
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002656
1058	CENPA, CENP-A, CenH3	centromere protein A	C00002656
1277	COL1A1, OI4	collagen, type I, alpha 1	C00002656
1282	COL4A1, HANAC, ICH, POREN1, arresten	collagen, type IV, alpha 1	C00002656
1436	CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R	colony stimulating factor 1 receptor (EC:2.7.10.1)	C00002656
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00002656
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00002656
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00002656
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002656
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00002656
24300			C00002656
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00002656
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00002656
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00002656
1577	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3	cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1)	C00002656
3491	CYR61, CCN1, GIG1, IGFBP10	cysteine-rich, angiogenic inducer, 61	C00002656
1611	DAP	death-associated protein	C00002656
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00002656
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00002656
22943	DKK1, DKK-1, SK	dickkopf WNT signaling pathway inhibitor 1	C00002656
3301	DNAJA1, DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSPF4, NEDD7, hDJ-2	DnaJ (Hsp40) homolog, subfamily A, member 1	C00002656
3337	DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1	DnaJ (Hsp40) homolog, subfamily B, member 1	C00002656
1786	DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT	DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37)	C00002656
1788	DNMT3A, DNMT3A2, M.HsaIIIA	DNA (cytosine-5-)-methyltransferase 3 alpha (EC:2.1.1.37)	C00002656
1789	DNMT3B, ICF, ICF1, M.HsaIIIB	DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37)	C00002656
1999	ELF3, EPR-1, ERT, ESE-1, ESX	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	C00002656
8772	FADD, MORT1	Fas (TNFRSF6)-associated via death domain	C00002656
81610	FAM83D, C20orf129, CHICA, dJ616B8.3	family with sequence similarity 83, member D	C00002656
26271	FBXO5, EMI1, FBX5, Fbxo31	F-box protein 5	C00002656
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00002656
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00002656
2495	FTH1, FHC, FTH, FTHL6, PIG15, PLIF	ferritin, heavy polypeptide 1 (EC:1.16.3.1)	C00002656
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00002656
2623	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT	GATA binding protein 1 (globin transcription factor 1)	C00002656
2624	GATA2, DCML, MONOMAC, NFE1B	GATA binding protein 2	C00002656
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00002656
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00002656
2937	GSS, GSHS	glutathione synthetase (EC:6.3.2.3)	C00002656
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00002656
2993	GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2	glycophorin A (MNS blood group)	C00002656
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00002656
3043	HBB, CD113t-C, beta-globin	hemoglobin, beta	C00002656
3009	HIST1H1B, H1, H1.5, H1B, H1F5, H1s-3	histone cluster 1, H1b	C00002656
3007	HIST1H1D, H1.3, H1D, H1F3, H1s-2	histone cluster 1, H1d	C00002656
3008	HIST1H1E, H1.4, H1E, H1F4, H1s-4, dJ221C16.5	histone cluster 1, H1e	C00002656
85235	HIST1H2AH, H2A/S, H2AFALii, H2AH, dJ86C11.1	histone cluster 1, H2ah	C00002656
8329	HIST1H2AI, H2A/c, H2AFC	histone cluster 1, H2ai	C00002656
8331	HIST1H2AJ, H2A/E, H2AFE, dJ160A22.4	histone cluster 1, H2aj	C00002656
8358	HIST1H3B, H3/l, H3FL	histone cluster 1, H3b	C00002656
8352	HIST1H3C, H3.1, H3/c, H3FC	histone cluster 1, H3c	C00002656
8359	HIST1H4A, H4FA	histone cluster 1, H4a	C00002656
8366	HIST1H4B, H4/I, H4FI	histone cluster 1, H4b	C00002656
8364	HIST1H4C, H4/g, H4FG, dJ221C16.1	histone cluster 1, H4c	C00002656
8367	HIST1H4E, H4/j, H4FJ	histone cluster 1, H4e	C00002656
8361	HIST1H4F, H4, H4/c, H4FC	histone cluster 1, H4f	C00002656
8365	HIST1H4H, H4/h, H4FH	histone cluster 1, H4h	C00002656
8362	HIST1H4K, H4/d, H4F2iii, H4FD, dJ160A22.1	histone cluster 1, H4k	C00002656
8337	HIST2H2AA3, H2A, H2A.2, H2A/O, H2A/q, H2AFO, H2a-615, HIST2H2AA	histone cluster 2, H2aa3	C00002656
317772	HIST2H2AB, H2AB	histone cluster 2, H2ab	C00002656
8338	HIST2H2AC, H2A, H2A-GL101, H2A/q, H2AFQ	histone cluster 2, H2ac	C00002656
8370	HIST2H4A, FO108, H4, H4/n, H4F2, H4FN, HIST2H4	histone cluster 2, H4a	C00002656
55355	HJURP, FAKTS, URLC9, hFLEG1	Holliday junction recognition protein	C00002656
3145	HMBS, PBG-D, PBGD, PORC, UPS	hydroxymethylbilane synthase (EC:2.5.1.61)	C00002656
3148	HMGB2, HMG2	high mobility group box 2	C00002656
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00002656
3306	HSPA2, HSP70-2, HSP70-3	heat shock 70kDa protein 2	C00002656
219844	HYLS1, HLS	hydrolethalus syndrome 1	C00002656
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00002656
3558	IL2, IL-2, TCGF, lymphokine	interleukin 2	C00002656
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002656
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002656
3688	ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	C00002656
3689	ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	C00002656
182	JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1	jagged 1	C00002656
81930	KIF18A, MS-KIF18A	kinesin family member 18A	C00002656
4254	KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7	KIT ligand	C00002656
3910	LAMA4, CMD1JJ, LAMA3, LAMA4*-1	laminin, alpha 4	C00002656
11061	LECT1, BRICD3, CHM-I, CHM1, MYETS1	leukocyte cell derived chemotaxin 1	C00002656
4000	LMNA, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1	lamin A/C	C00002656
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002656
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002656
8932	MBD2, DMTase, NY-CO-41	methyl-CpG binding domain protein 2	C00002656
4257	MGST1, GST12, MGST, MGST-I	microsomal glutathione S-transferase 1 (EC:2.5.1.18)	C00002656
4323	MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS	matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80)	C00002656
4324	MMP15, MT2-MMP, MTMMP2, SMCP-2	matrix metallopeptidase 15 (membrane-inserted) (EC:3.4.24.-)	C00002656
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00002656
4314	MMP3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1	matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC:3.4.24.17)	C00002656
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00002656
4352	MPL, C-MPL, CD110, MPLV, THCYT2, TPOR	myeloproliferative leukemia virus oncogene	C00002656
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00002656
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00002656
4778	NFE2, NF-E2, p45	nuclear factor, erythroid 2	C00002656
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00002656
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00002656
5036	PA2G4, EBP1, HG4-1, p38-2G4	proliferation-associated 2G4, 38kDa	C00002656
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00002656
25796	PGLS, 6PGL	6-phosphogluconolactonase (EC:3.1.1.31)	C00002656
5429	POLH, RAD30, RAD30A, XP-V, XPV	polymerase (DNA directed), eta (EC:2.7.7.7)	C00002656
8493	PPM1D, PP2C-DELTA, WIP1	protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16)	C00002656
5052	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2	peroxiredoxin 1 (EC:1.11.1.15)	C00002656
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00002656
84722	PSRC1, DDA3, FP3214	proline/serine-rich coiled-coil 1	C00002656
9401	RECQL4, RECQ4	RecQ protein-like 4 (EC:3.6.4.12)	C00002656
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002656
860	RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA	runt-related transcription factor 2	C00002656
27244	SESN1, PA26, SEST1	sestrin 1	C00002656
83667	SESN2, HI95, SES2, SEST2	sestrin 2	C00002656
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00002656
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00002656
6688	SPI1, OF, PU.1, SFPI1, SPI-1, SPI-A	spleen focus forming virus (SFFV) proviral integration oncogene	C00002656
8614	STC2, STC-2, STCRP	stanniocalcin 2	C00002656
7037	TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90	transferrin receptor	C00002656
7077	TIMP2, CSC-21K, DDC8	TIMP metallopeptidase inhibitor 2	C00002656
25976	TIPARP, ARTD14, PARP7, pART14	TCDD-inducible poly(ADP-ribose) polymerase (EC:2.4.2.30)	C00002656
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002656
8795	TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	C00002656
8793	TNFRSF10D, CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD	tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain	C00002656
8718	TNFRSF25, APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR	tumor necrosis factor receptor superfamily, member 25	C00002656
3604	TNFRSF9, 4-1BB, CD137, CDw137, ILA	tumor necrosis factor receptor superfamily, member 9	C00002656
8742	TNFSF12, APO3L, DR3LG, TWEAK	tumor necrosis factor (ligand) superfamily, member 12	C00002656
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00002656
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002656
94241	TP53INP1, SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1	tumor protein p53 inducible nuclear protein 1	C00002656
8717	TRADD, Hs.89862	TNFRSF1A-associated via death domain	C00002656
9618	TRAF4, CART1, MLN62, RNF83	TNF receptor-associated factor 4	C00002656
286827	TRIM59, MRF1, RNF104, TRIM57, TSBF1	tripartite motif containing 59	C00002656
8989	TRPA1, ANKTM1, FEPS	transient receptor potential cation channel, subfamily A, member 1	C00002656
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00002656
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00002656
7474	WNT5A, hWNT5A	wingless-type MMTV integration site family, member 5A	C00002656
7486	WRN, RECQ3, RECQL2, RECQL3	Werner syndrome, RecQ helicase-like (EC:3.6.4.12)	C00002656
10349	ABCA10, EST698739	ATP-binding cassette, sub-family A (ABC1), member 10	C00002638
154664	ABCA13	ATP-binding cassette, sub-family A (ABC1), member 13	C00002638
150000	ABCC13, C21orf73, PRED6	ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene	C00002638
130013	ACMSD	aminocarboxymuconate semialdehyde decarboxylase (EC:4.1.1.45)	C00002638
94	ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I	activin A receptor type II-like 1 (EC:2.7.11.30)	C00002638
8728	ADAM19, MADDAM, MLTNB	ADAM metallopeptidase domain 19	C00002638
8748	ADAM20	ADAM metallopeptidase domain 20	C00002638
8756	ADAM7, ADAM_7, ADAM-7, EAPI, GP-83, GP83	ADAM metallopeptidase domain 7	C00002638
9508	ADAMTS3, ADAMTS-4	ADAM metallopeptidase with thrombospondin type 1 motif, 3 (EC:3.4.24.-)	C00002638
56999	ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	C00002638
155	ADRB3, BETA3AR	adrenoceptor beta 3	C00002638
121536	AEBP2	AE binding protein 2	C00002638
60312	AFAP1, AFAP, AFAP-110, AFAP110	actin filament associated protein 1	C00002638
84871	AGBL4, CCP6	ATP/GTP binding protein-like 4	C00002638
56894	AGPAT3, LPAAT-GAMMA1, LPAAT3	1-acylglycerol-3-phosphate O-acyltransferase 3 (EC:2.3.1.51)	C00002638
79026	AHNAK, AHNAKRS	AHNAK nucleoprotein	C00002638
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00002638
401138	AMTN, UNQ689	amelotin	C00002638
26057	ANKRD17, GTAR, NY-BR-16	ankyrin repeat domain 17	C00002638
200539	ANKRD23, DARP, MARP3	ankyrin repeat domain 23	C00002638
1174	AP1S1, AP19, CLAPS1, MEDNIK, SIGMA1A, WUGSC:H_DJ0747G18.2	adaptor-related protein complex 1, sigma 1 subunit	C00002638
55937	APOM, G3a, HSPC336, NG20, apo-M	apolipoprotein M	C00002638
54840	APTX, AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT	aprataxin	C00002638
23647	ARFIP2, POR1	ADP-ribosylation factor interacting protein 2	C00002638
9181	ARHGEF2, GEF, GEF-H1, GEFH1, LFP40, P40	Rho/Rac guanine nucleotide exchange factor (GEF) 2	C00002638
402	ARL2, ARFL2	ADP-ribosylation factor-like 2	C00002638
23204	ARL6IP1, AIP1, ARL6IP, ARMER	ADP-ribosylation factor-like 6 interacting protein 1	C00002638
170302	ARX, CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS	aristaless related homeobox	C00002638
55616	ASAP3, ACAP4, CENTB6, DDEFL1, UPLC1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3	C00002638
439	ASNA1, ARSA-I, ARSA1, ASNA-I, GET3, TRC40, hASNA-I	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) (EC:3.6.3.16)	C00002638
83858	ATAD3B, AAA-TOB3, TOB3	ATPase family, AAA domain containing 3B	C00002638
1388	ATF6B, CREB-RP, CREBL1, G13	activating transcription factor 6 beta	C00002638
338707	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4 (EC:2.4.1.244)	C00002638
9529	BAG5, BAG-5	BCL2-associated athanogene 5	C00002638
10286	BCAS2, DAM1, SPF27, Snt309	breast carcinoma amplified sequence 2	C00002638
10295	BCKDK, BCKDKD, BDK	branched chain ketoacid dehydrogenase kinase (EC:2.7.11.4)	C00002638
658	BMPR1B, ALK-6, ALK6, CDw293	bone morphogenetic protein receptor, type IB (EC:2.7.11.30)	C00002638
663	BNIP2, BNIP-2, NIP2	BCL2/adenovirus E1B 19kDa interacting protein 2	C00002638
84446	BRSK1, hSAD1	BR serine/threonine kinase 1 (EC:2.7.11.1 2.7.11.26)	C00002638
684	BST2, CD317, TETHERIN	bone marrow stromal cell antigen 2	C00002638
11120	BTN2A1, BK14H9.1, BT2.1, BTF1, DJ3E1.1	butyrophilin, subfamily 2, member A1	C00002638
9256	BZRAP1, PBR-IP, PRAX-1, PRAX1, RIM-BP1, RIMBP1	benzodiazapine receptor (peripheral) associated protein 1	C00002638
161502	C15orf26	chromosome 15 open reading frame 26	C00002638
84529	C15orf41, HH114	chromosome 15 open reading frame 41	C00002638
64073	C19orf33, H2RSP, IMUP, IMUP-1, IMUP-2	chromosome 19 open reading frame 33	C00002638
84808	C1orf170, RP11-54O7.8	chromosome 1 open reading frame 170	C00002638
10485	C1orf61, CROC4	chromosome 1 open reading frame 61	C00002638
127795	C1orf87	chromosome 1 open reading frame 87	C00002638
713	C1QB	complement component 1, q subcomponent, B chain	C00002638
59284	CACNG7	calcium channel, voltage-dependent, gamma subunit 7	C00002638
84290	CAPNS2	calpain, small subunit 2	C00002638
23466	CBX6	chromobox homolog 6	C00002638
55749	CCAR1, RP11-437A18.1	cell division cycle and apoptosis regulator 1	C00002638
80129	CCDC170, C6orf97, bA282P11.1	coiled-coil domain containing 170	C00002638
79140	CCDC28B, RP4-622L5.5	coiled-coil domain containing 28B	C00002638
151195	CCNYL1	cyclin Y-like 1	C00002638
10694	CCT8, C21orf112, Cctq, D21S246, PRED71	chaperonin containing TCP1, subunit 8 (theta)	C00002638
977	CD151, GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24	CD151 molecule (Raph blood group)	C00002638
11126	CD160, BY55, NK1, NK28	CD160 molecule	C00002638
283316	CD163L1, CD163B, M160	CD163 molecule-like 1	C00002638
10421	CD2BP2, FWP010, LIN1, PPP1R59, Snu40, U5-52K	CD2 (cytoplasmic tail) binding protein 2	C00002638
917	CD3G, CD3-GAMMA, T3G	CD3g molecule, gamma (CD3-TCR complex)	C00002638
5127	CDK16, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1	cyclin-dependent kinase 16 (EC:2.7.11.22)	C00002638
634	CEACAM1, BGP, BGP1, BGPI	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	C00002638
170482	CLEC4C, BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150	C-type lectin domain family 4, member C	C00002638
22866	CNKSR2, CNK2, KSR2, MAGUIN	connector enhancer of kinase suppressor of Ras 2	C00002638
1308	COL17A1, BA16H23.2, BP180, BPA-2, BPAG2, LAD-1	collagen, type XVII, alpha 1	C00002638
1360	CPB1, CPB, PASP, PCPB	carboxypeptidase B1 (tissue) (EC:3.4.17.2)	C00002638
1363	CPE	carboxypeptidase E (EC:3.4.17.10)	C00002638
57699	CPNE5, COPN5, CPN5	copine V	C00002638
113612	CYP2U1, P450TEC, SPG49, SPG56	cytochrome P450, family 2, subfamily U, polypeptide 1 (EC:1.14.14.1)	C00002638
326709			C00002638
9879	DDX46, PRPF5, Prp5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 (EC:3.6.4.13)	C00002638
1730	DIAPH2, DIA, DIA2, DRF2, POF, POF2	diaphanous-related formin 2	C00002638
22839	DLGAP4, DAP4, DLP4, RP5-977B1.6, SAPAP4	discs, large (Drosophila) homolog-associated protein 4	C00002638
1745	DLX1	distal-less homeobox 1	C00002638
1657	DMXL1	Dmx-like 1	C00002638
56171	DNAH7	dynein, axonemal, heavy chain 7	C00002638
4189	DNAJB9, ERdj4, MDG-1, MDG1, MST049, MSTP049	DnaJ (Hsp40) homolog, subfamily B, member 9	C00002638
29952	DPP7, DPP2, DPPII, QPP	dipeptidyl-peptidase 7 (EC:3.4.14.2)	C00002638
1808	DPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2	dihydropyrimidinase-like 2	C00002638
1889	ECE1, ECE	endothelin converting enzyme 1 (EC:3.4.24.71)	C00002638
80820	EEPD1, HSPC107	endonuclease/exonuclease/phosphatase family domain containing 1	C00002638
80258	EFHC2, dJ1158H2.1	EF-hand domain (C-terminal) containing 2	C00002638
1944	EFNA3, EFL2, EPLG3, Ehk1-L, LERK3	ephrin-A3	C00002638
10278	EFS, CAS3, CASS3, EFS1, EFS2, HEFS, SIN	embryonal Fyn-associated substrate	C00002638
79631	EFTUD1, FAM42A, HsT19294, RIA1	elongation factor Tu GTP binding domain containing 1	C00002638
23741	EID1, C15orf3, CRI1, EID-1, IRO45620, PTD014, RBP21	EP300 interacting inhibitor of differentiation 1	C00002638
1991	ELANE, ELA2, GE, HLE, HNE, NE, PMN-E, SCN1	elastase, neutrophil expressed (EC:3.4.21.37)	C00002638
2018	EMX2	empty spiracles homeobox 2	C00002638
5167	ENPP1, ARHR2, M6S1, NPP1, NPPS, PC-1, PCA1, PDNP1	ectonucleotide pyrophosphatase/phosphodiesterase 1 (EC:3.1.4.1 3.6.1.9)	C00002638
2059	EPS8	epidermal growth factor receptor pathway substrate 8	C00002638
8288	EPX, EPO, EPP, EPX-PEN	eosinophil peroxidase (EC:1.11.1.7)	C00002638
23085	ERC1, Cast2, ELKS, RAB6IP2	ELKS/RAB6-interacting/CAST family member 1	C00002638
711	ERC2-IT1, C1orf1, C3orf51, Po42	ERC2 intronic transcript 1 (non-protein coding)	C00002638
2124	EVI2B, CD361, D17S376, EVDB	ecotropic viral integration site 2B	C00002638
161829	EXD1, EXDL1	exonuclease 3'-5' domain containing 1	C00002638
2165	F13B, FXIIIB	coagulation factor XIII, B polypeptide (EC:2.3.2.13)	C00002638
131177	FAM3D, EF7, OIT1	family with sequence similarity 3, member D	C00002638
51571	FAM49B, L1	family with sequence similarity 49, member B	C00002638
115795	FANCD2OS, C3orf24	FANCD2 opposite strand	C00002638
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00002638
80204	FBXO11, FBX11, PRMT9, UBR6, VIT1	F-box protein 11	C00002638
157574	FBXO16, FBX16	F-box protein 16	C00002638
2250	FGF5, HBGF-5, Smag-82	fibroblast growth factor 5	C00002638
2261	FGFR3, ACH, CD333, CEK2, HSFGFR3EX, JTK4	fibroblast growth factor receptor 3 (EC:2.7.10.1)	C00002638
91010	FMNL3, FHOD3, WBP-3, WBP3	formin-like 3	C00002638
8790	FPGT, GFPP	fucose-1-phosphate guanylyltransferase (EC:2.7.7.30)	C00002638
80144	FRAS1	Fraser syndrome 1	C00002638
9758	FRMPD4, PDZD10, PDZK10	FERM and PDZ domain containing 4	C00002638
2581	GALC	galactosylceramidase (EC:3.2.1.46)	C00002638
64762	GAREM, C18orf11, FAM59A, Gm944	GRB2 associated, regulator of MAPK1	C00002638
10755	GIPC1, C19orf3, GIPC, GLUT1CBP, Hs.6454, IIP-1, NIP, RGS19IP1, SEMCAP, SYNECTIIN, SYNECTIN, TIP-2	GIPC PDZ domain containing family, member 1	C00002638
83468	GLT8D2	glycosyltransferase 8 domain containing 2	C00002638
2766	GMPR, GMPR1	guanosine monophosphate reductase (EC:1.7.1.7)	C00002638
29889	GNL2, HUMAUANTIG, NGP1, Ngp-1	guanine nucleotide binding protein-like 2 (nucleolar)	C00002638
2719	GPC3, DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1	glypican 3	C00002638
2820	GPD2, GDH2, GPDM, mGPDH	glycerol-3-phosphate dehydrogenase 2 (mitochondrial) (EC:1.1.5.3)	C00002638
151556	GPR155, DEP.7, DEPDC3, PGR22	G protein-coupled receptor 155	C00002638
2849	GPR26	G protein-coupled receptor 26	C00002638
2854	GPR32, RVDR1	G protein-coupled receptor 32	C00002638
9290	GPR55	G protein-coupled receptor 55	C00002638
55507	GPRC5D	G protein-coupled receptor, family C, group 5, member D	C00002638
284110	GSDMA, GSDM, GSDM1	gasdermin A	C00002638
2977	GUCY1A2, GC-SA2, GUC1A2	guanylate cyclase 1, soluble, alpha 2 (EC:4.6.1.2)	C00002638
9421	HAND1, Hxt, Thing1, bHLHa27, eHand	heart and neural crest derivatives expressed 1	C00002638
3024	HIST1H1A, H1.1, H1A, H1F1, HIST1	histone cluster 1, H1a	C00002638
8334	HIST1H2AC, H2A/l, H2AFL, dJ221C16.4	histone cluster 1, H2ac	C00002638
3131	HLF	hepatic leukemia factor	C00002638
3218	HOXB8, HOX2, HOX2D, Hox-2.4	homeobox B8	C00002638
84343	HPS3, SUTAL	Hermansky-Pudlak syndrome 3	C00002638
3283	HSD3B1, 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (EC:1.1.1.145 5.3.3.1)	C00002638
27336	HTATSF1, TAT-SF1, TATSF1, dJ196E23.2	HIV-1 Tat specific factor 1	C00002638
3437	IFIT3, CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G	interferon-induced protein with tetratricopeptide repeats 3	C00002638
9543	IGDCC3, HsT18880, PUNC	immunoglobulin superfamily, DCC subclass, member 3	C00002638
51561	IL23A, IL-23, IL-23A, IL23P19, P19, SGRF	interleukin 23, alpha subunit p19	C00002638
3563	IL3RA, CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra	interleukin 3 receptor, alpha (low affinity)	C00002638
3572	IL6ST, CD130, CDW130, GP130, IL-6RB	interleukin 6 signal transducer (gp130, oncostatin M receptor)	C00002638
9118	INA, NEF5, NF-66, TXBP-1	internexin neuronal intermediate filament protein, alpha	C00002638
8821	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa (EC:3.1.3.66)	C00002638
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00002638
9196	KCNAB3, AKR6A9, KCNA3.1B, KCNA3B, KV-BETA-3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	C00002638
79734	KCTD17	potassium channel tetramerization domain containing 17	C00002638
79070	KDELC1, EP58, KDEL1	KDEL (Lys-Asp-Glu-Leu) containing 1	C00002638
55083	KIF26B	kinesin family member 26B	C00002638
90293	KLHL13, BKLHD2, KIAA1309	kelch-like family member 13	C00002638
8302	KLRC4, NKG2-F, NKG2F	killer cell lectin-like receptor subfamily C, member 4	C00002638
197021	LCTL, KLG, KLPH	lactase-like	C00002638
56891	LGALS14, CLC2, PPL13	lectin, galactoside-binding, soluble, 14	C00002638
79166	LILRP2, CD85m, ILT10, LILRA5	leukocyte immunoglobulin-like receptor pseudogene 2	C00002638
4041	LRP5, BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2	low density lipoprotein receptor-related protein 5	C00002638
4040	LRP6, ADCAD2	low density lipoprotein receptor-related protein 6	C00002638
64101	LRRC4, NGL-2	leucine rich repeat containing 4	C00002638
80059	LRRTM4	leucine rich repeat transmembrane neuronal 4	C00002638
7975	MAFK, NFE2U, P18	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	C00002638
11183	MAP4K5, GCKR, KHS, KHS1, MAPKKKK5	mitogen-activated protein kinase kinase kinase kinase 5 (EC:2.7.11.1)	C00002638
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00002638
84515	MCM8, C20orf154, dJ967N21.5	minichromosome maintenance complex component 8 (EC:3.6.4.12)	C00002638
4188	MDFI, I-MF, I-mfa	MyoD family inhibitor	C00002638
4239	MFAP4	microfibrillar-associated protein 4	C00002638
90007	MIDN	midnolin	C00002638
4288	MKI67, KIA, MIB-1	marker of proliferation Ki-67	C00002638
93380	MMGT1, EMC5, TMEM32	membrane magnesium transporter 1	C00002638
245802	MS4A6E	membrane-spanning 4-domains, subfamily A, member 6E	C00002638
25902	MTHFD1L, FTHFSDC1, MTC1THFS, dJ292B18.2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (EC:6.3.4.3)	C00002638
4597	MVD, FP17780, MPD	mevalonate (diphospho) decarboxylase (EC:4.1.1.33)	C00002638
140469	MYO3B	myosin IIIB (EC:2.7.11.1)	C00002638
83988	NCALD	neurocalcin delta	C00002638
257194	NEGR1, DMML2433, IGLON4, KILON, Ntra	neuronal growth regulator 1	C00002638
129807	NEU4	sialidase 4 (EC:3.2.1.18)	C00002638
85407	NKD1, Naked1	naked cuticle homolog 1 (Drosophila)	C00002638
9111	NMI	N-myc (and STAT) interactor	C00002638
122945	NOXRED1, C14orf148	NADP-dependent oxidoreductase domain containing 1	C00002638
7025	NR2F1, COUP-TFI, EAR-3, EAR3, ERBAL3, NR2F2, SVP44, TCFCOUP1, TFCOUP1	nuclear receptor subfamily 2, group F, member 1	C00002638
8828	NRP2, NP2, NPN2, PRO2714, VEGF165R2	neuropilin 2	C00002638
4909	NTF4, GLC10, GLC1O, NT-4, NT-4/5, NT-5, NT4, NT5, NTF5	neurotrophin 4	C00002638
283298	OLFML1, UNQ564	olfactomedin-like 1	C00002638
23762	OSBP2, HLM, ORP-4, ORP4, OSBPL1, OSBPL4	oxysterol binding protein 2	C00002638
114885	OSBPL11, ORP-11, ORP11, OSBP12, TCCCIA00292	oxysterol binding protein-like 11	C00002638
5013	OTX1	orthodenticle homeobox 1	C00002638
11252	PACSIN2, SDPII	protein kinase C and casein kinase substrate in neurons 2	C00002638
8505	PARG, PARG99	poly (ADP-ribose) glycohydrolase (EC:3.2.1.143)	C00002638
84108	PCGF6, MBLR, RNF134	polycomb group ring finger 6	C00002638
55251	PCMTD2, C20orf36	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2	C00002638
80003	PCNXL2	pecanex-like 2 (Drosophila)	C00002638
5174	PDZK1, CAP70, CLAMP, NHERF-3, NHERF3, PDZD1	PDZ domain containing 1	C00002638
5196	PF4, CXCL4, PF-4, SCYB4	platelet factor 4	C00002638
55276	PGM2	phosphoglucomutase 2 (EC:5.4.2.2 5.4.2.7)	C00002638
9091	PIGQ, GPI1, c407A10.1	phosphatidylinositol glycan anchor biosynthesis, class Q (EC:2.4.1.198)	C00002638
5300	PIN1, DOD, UBL5	peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (EC:5.2.1.8)	C00002638
23760	PITPNB, PI-TP-beta, PtdInsTP, VIB1B	phosphatidylinositol transfer protein, beta	C00002638
5314	PKHD1, ARPKD, FCYT, TIGM1	polycystic kidney and hepatic disease 1 (autosomal recessive)	C00002638
5427	POLE2, DPE2	polymerase (DNA directed), epsilon 2, accessory subunit (EC:2.7.7.7)	C00002638
51535	PPHLN1, HSPC232	periphilin 1	C00002638
5553	PRG2, BMPG, MBP, MBP1	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	C00002638
5613	PRKX, PKX1	protein kinase, X-linked (EC:2.7.11.1)	C00002638
3275	PRMT2, HRMT1L1	protein arginine methyltransferase 2 (EC:2.1.1.125)	C00002638
285800	PRR18	proline rich 18	C00002638
5396	PRRX1, AGOTC, PHOX1, PMX1, PRX-1, PRX1	paired related homeobox 1	C00002638
5645	PRSS2, TRY2, TRY8, TRYP2	protease, serine, 2 (trypsin 2) (EC:3.4.21.4)	C00002638
5719	PSMD13, HSPC027, Rpn9, S11, p40.5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	C00002638
5709	PSMD3, P58, RPN3, S3, TSTA2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	C00002638
22930	RAB3GAP1, P130, RAB3GAP, RAB3GAP130, WARBM1	RAB3 GTPase activating protein subunit 1 (catalytic)	C00002638
51560	RAB6B	RAB6B, member RAS oncogene family	C00002638
153020	RASGEF1B, GPIG4	RasGEF domain family, member 1B	C00002638
10739	RFPL2, RNF79	ret finger protein-like 2	C00002638
10738	RFPL3	ret finger protein-like 3	C00002638
727800	RNF208	ring finger protein 208	C00002638
6197	RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2	ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1)	C00002638
54665	RSBN1, ROSBIN, RP11-324J2.1	round spermatid basic protein 1	C00002638
6291	SAA4, C-SAA, CSAA	serum amyloid A4, constitutive	C00002638
51097	SCCPDH, NET11, RP11-439E19.2	saccharopine dehydrogenase (putative) (EC:1.5.1.9)	C00002638
6324	SCN1B, ATFB13, BRGDA5, GEFSP1	sodium channel, voltage-gated, type I, beta subunit	C00002638
6385	SDC4, SYND4	syndecan 4	C00002638
6406	SEMG1, CT103, SEMG, SGI, dJ172H20.2	semenogelin I	C00002638
5104	SERPINA5, PAI-3, PAI3, PCI, PCI-B, PLANH3, PROCI	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	C00002638
3053	SERPIND1, D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	C00002638
23451	SF3B1, Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155	splicing factor 3b, subunit 1, 155kDa	C00002638
6425	SFRP5, SARP3	secreted frizzled-related protein 5	C00002638
118980	SFXN2	sideroflexin 2	C00002638
6456	SH3GL2, CNSA2, EEN-B1, SH3D2A, SH3P4	SH3-domain GRB2-like 2	C00002638
23309	SIN3B	SIN3 transcription regulator family member B	C00002638
9058	SLC13A2, NADC1, NaCT, NaDC-1, SDCT1	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	C00002638
51296	SLC15A3, OCTP, PHT2, PTR3	solute carrier family 15 (oligopeptide transporter), member 3	C00002638
217	ALDH2, ALDH-E2, ALDHI, ALDM	aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3)	C00002656
151295	SLC23A3, E2BP3, SVCT3, Yspl1	solute carrier family 23, member 3	C00002638
83884	SLC25A2, ORC2, ORNT2	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2	C00002638
10999	SLC27A4, ACSVL4, FATP4, IPS	solute carrier family 27 (fatty acid transporter), member 4 (EC:6.2.1.-)	C00002638
84889	SLC7A3, ATRC3, CAT-3, CAT3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	C00002638
81796	SLCO5A1, OATP-J, OATP-RP4, OATP5A1, OATPRP4, SLC21A15	solute carrier organic anion transporter family, member 5A1	C00002638
79753	SNIP1, PMRED	Smad nuclear interacting protein 1	C00002638
122809	SOCS4, SOCS7	suppressor of cytokine signaling 4	C00002638
221178	SPATA13, ARHGEF29, ASEF2	spermatogenesis associated 13	C00002638
64847	SPATA20, SSP411, Tisp78	spermatogenesis associated 20	C00002638
10558	SPTLC1, HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI	serine palmitoyltransferase, long chain base subunit 1 (EC:2.3.1.50)	C00002638
9754	STARD8, ARHGAP38, DLC3, STARTGAP3	StAR-related lipid transfer (START) domain containing 8	C00002638
85360	SYDE1, 7h3	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	C00002638
8189	SYMPK, SPK, SYM	symplekin	C00002638
6886	TAL1, SCL, TCL5, bHLHa17, tal-1	T-cell acute lymphocytic leukemia 1	C00002638
23435	TARDBP, ALS10, TDP-43	TAR DNA binding protein	C00002638
6938	TCF12, CRS3, HEB, HTF4, HsT17266, bHLHb20	transcription factor 12	C00002638
6947	TCN1, TC-1, TC1, TCI	transcobalamin I (vitamin B12 binding protein, R binder family)	C00002638
26136	TES, TESS, TESS-2	testis derived transcript (3 LIM domains)	C00002638
56156	TEX13B, TGC3B, TSGA5	testis expressed 13B	C00002638
7043	TGFB3, ARVD, ARVD1, TGF-beta3	transforming growth factor, beta 3	C00002638
7092	TLL1, ASD6, TLL	tolloid-like 1 (EC:3.4.24.-)	C00002638
25789	TMEM59L, BSMAP, C19orf4	transmembrane protein 59-like	C00002638
54863	TOR4A, C9orf167	torsin family 4, member A	C00002638
9697	TRAM2	translocation associated membrane protein 2	C00002638
11181	TREH, TRE, TREA	trehalase (brush-border membrane glycoprotein) (EC:3.2.1.28)	C00002638
7248	TSC1, LAM, TSC	tuberous sclerosis 1	C00002638
9819	TSC22D2, TILZ4a, TILZ4b, TILZ4c	TSC22 domain family, member 2	C00002638
128553	TSHZ2, C20orf17, OVC10-2, TSH2, ZABC2, ZNF218	teashirt zinc finger homeobox 2	C00002638
118491	TTC18	tetratricopeptide repeat domain 18	C00002638
55001	TTC22	tetratricopeptide repeat domain 22	C00002638
7289	TULP3, TUBL3	tubby like protein 3	C00002638
51619	UBE2D4, HBUCE1	ubiquitin-conjugating enzyme E2D 4 (putative) (EC:6.3.2.19)	C00002638
9040	UBE2M, UBC-RS2, UBC12, hUbc12	ubiquitin-conjugating enzyme E2M (EC:6.3.2.19)	C00002638
29979	UBQLN1, DA41, DSK2, PLIC-1, UBQN, XDRP1	ubiquilin 1	C00002638
84101	USP44	ubiquitin specific peptidase 44 (EC:3.4.19.12)	C00002638
51118	UTP11L, CGI94	UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)	C00002638
157680	VPS13B, CHS1, COH1	vacuolar protein sorting 13 homolog B (yeast)	C00002638
23339	VPS39, TLP, VAM6, hVam6p	vacuolar protein sorting 39 homolog (S. cerevisiae)	C00002638
146177	VWA3A	von Willebrand factor A domain containing 3A	C00002638
126820	WDR63, DIC3, NYD-SP29, RP11-507C22.2	WD repeat domain 63	C00002638
80326	WNT10A, OODD, SSPS, STHAG4	wingless-type MMTV integration site family, member 10A	C00002638
9502	XAGE2, CT12.2, GAGED3, XAGE-2	X antigen family, member 2	C00002638
26137	ZBTB20, DPZF, HOF, ODA-8S, ZNF288	zinc finger and BTB domain containing 20	C00002638
51043	ZBTB7B, THPOK, ZBTB15, ZFP-67, ZFP67, ZNF857B, c-KROX, hcKROX	zinc finger and BTB domain containing 7B	C00002638
51201	ZDHHC2, DHHC2, ZNF372	zinc finger, DHHC-type containing 2 (EC:2.3.1.225)	C00002638
55888	ZKSCAN7, ZFP, ZNF167, ZNF448, ZNF64, ZSCAN39	zinc finger with KRAB and SCAN domains 7	C00002638
7700	ZNF141, D4S90, PAPA6, pHZ-44	zinc finger protein 141	C00002638
162967	ZNF320, ZFPL	zinc finger protein 320	C00002638
117608	ZNF354B, KID2	zinc finger protein 354B	C00002638
7592	ZNF41, MRX89	zinc finger protein 41	C00002638
84330	ZNF414, ZFP414	zinc finger protein 414	C00002638
158399	ZNF483, ZKSCAN16, ZSCAN48	zinc finger protein 483	C00002638
162968	ZNF497	zinc finger protein 497	C00002638
93474	ZNF670	zinc finger protein 670	C00002638
347344	ZNF81, HFZ20, MRX45, dJ54B20.6	zinc finger protein 81	C00002638
7783	ZP2, ZPA, Zp-2	zona pellucida glycoprotein 2 (sperm receptor)	C00002638

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions