Althaea rosea
Species
KNApSAcK Entry
| Organism name | Althaea rosea |
|---|---|
| Genus | Althaea |
| Family | Malvaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Althaea rosea |
|---|---|
| Linked NCBI taxonomy ID | 1219290 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Malvaceae |
|---|---|
| ID | 3629 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (10)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006666
|
Seranin
|
No. 1 | No. 15 |
|
||||
|
C00011341
|
Pelargonidin 7-glucoside
|
No. 2 | No. 15 |
|
||||
|
C00006723
|
Petunidin 3-rhamnoside
|
No. 2 | No. 15 |
|
||||
|
C00005341
|
Herbacetin 8-glucoside
|
No. 2 | No. 15 |
|
||||
|
C00000008
|
GA8
/ Gibberellin A8 |
No. 40 | No. 41 |
|
||||
|
C00000003
|
GA3
/ Gibberellin A3 |
CHEMBL513241
CHEMBL566653 CHEMBL1232952 CHEMBL1476967 CHEMBL1487394 |
C007842
|
10 / 18 / 17 | No. 40 | No. 41 |
|
|
|
C00000009
|
GA9
/ Gibberellin A9 |
No. 40 | No. 41 |
|
||||
|
C00000001
|
GA1
/ Gibberellin A1 |
C422660
|
No. 40 | No. 41 |
|
|||
|
C00000152
|
p-Coumaric acid
|
CHEMBL66879
CHEMBL2336752 |
C032171
|
23 / 13 / 18 | 6 / 1 | No. 904 | No. 6 |
|
|
C00002674
|
Syringic acid
/ 4-Hydroxy-3,5-dimethoxybenzoic acid |
CHEMBL1414
|
C001945
|
12 / 3 / 5 | No. 1073 |
|
Human Protein / Gene in interactions
33 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P22748 | Carbonic anhydrase 4 | Lyase | C00000152 C00002674 | 1 / 1 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000152 C00002674 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000152 C00002674 | 0 / 1 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000152 C00002674 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00000152 C00002674 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000152 C00002674 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000152 C00002674 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000152 C00002674 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000152 C00002674 | 1 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000152 C00002674 | 1 / 2 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000152 C00002674 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000152 C00002674 | 0 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000152 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000003 | 0 / 1 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000003 | 11 / 10 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000152 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000152 | 1 / 8 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000003 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00000003 | 0 / 0 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000152 | 3 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000152 | 0 / 3 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000003 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00000152 | 4 / 2 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000003 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000152 | 0 / 0 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000152 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000152 | 1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000003 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000003 | 0 / 1 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000152 | 1 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000003 | 3 / 4 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000152 | 1 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000003 | 1 / 0 |
6 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000152
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00000152
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00000152
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00000152
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000152
|
| 7299 | TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | tyrosinase (EC:1.14.18.1) |
C00000152
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (31)
| OMIM | preferred title | UniProt |
|---|---|---|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P00533
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
KEGG DISEASE (35)
| KEGG | name | UniProt |
|---|---|---|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
|
| H00022 | Bladder cancer |
P00533
(related)
|
| H00028 | Choriocarcinoma |
P00533
(related)
|
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|