PCIDB

Pharbitis purpurea

Species

KNApSAcK Entry

Organism name Pharbitis purpurea
Genus Pharbitis
Family Convolvulaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ipomoea
Linked NCBI taxonomy ID 4119
Linked level genus

Family

Family in NCBI taxonomy Convolvulaceae
ID 4118

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (15)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00000003 External link 512 GA3
/ Gibberellin A3
CHEMBL513241
CHEMBL566653
CHEMBL1232952
CHEMBL1476967
CHEMBL1487394
C007842
10 / 18 / 17 No. 40 No. 41
C00000005 External link 512 GA5
/ Gibberellin A5
No. 40 No. 41
C00000008 External link 512 GA8
/ Gibberellin A8
No. 40 No. 41
C00000044 External link 512 GA44
/ Gibberellin A44
No. 40 No. 41
C00000034 External link 512 GA34
/ Gibberellin A34
No. 40 No. 41
C00000020 External link 512 GA20
/ Gibberellin A20
No. 40 No. 41
C00000026 External link 512 GA26
/ Gibberellin A26
No. 40 No. 41
C00000029 External link 512 GA29
/ Gibberellin A29
No. 40 No. 41
C00000027 External link 512 GA27
/ Gibberellin A27
No. 40 No. 41
C00000181 External link 512 Castasterone
C083545
No. 68 No. 11
C00000189 External link 512 Brassinone
/ Norcastasterone
/ 28-Norcastasterone
No. 68 No. 11
C00000019 External link 512 GA19
/ Gibberellin A19
C120175
No. 187 No. 41
C00000053 External link 512 GA53
/ Gibberellin A53
No. 187 No. 41
C00000017 External link 512 GA17
/ Gibberellin A17
No. 187 No. 41
C00000211 External link 512 Phenylglyoxal
CHEMBL233632
D010658
5 / 1 / 1 3 / 0 No. 2578 No. 9

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000003 1 / 0
P02545 Prelamin-A/C Unclassified protein C00000003 11 / 10
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000003 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00000211 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000003 2 / 0
O75496 Geminin Unclassified protein C00000003 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00000003 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00000211 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000003 0 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00000211 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000003 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000003 0 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00000211 0 / 0
P10275 Androgen receptor NR3C4 C00000003 3 / 4
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00000211 1 / 1

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
10327 AKR1A1, ALDR1, ALR, ARM, DD3 aldo-keto reductase family 1, member A1 (aldehyde reductase) (EC:1.1.1.2) C00000211
231 AKR1B1, ADR, ALDR1, ALR2, AR aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) C00000211
2530 FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (EC:2.4.1.68) C00000211

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8

KEGG DISEASE (18)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)