KNApSAcK Metabolite C00000211
Metabolite
KNApSAcK Entry
| id | C00000211 |
|---|---|
| Name | Phenylglyoxal |
| CAS RN | 1074-12-0 |
| Standard InChI | InChI=1S/C8H6O2/c9-6-8(10)7-4-2-1-3-5-7/h1-6H |
| Standard InChI (Main Layer) | InChI=1S/C8H6O2/c9-6-8(10)7-4-2-1-3-5-7/h1-6H |
Cluster
| Phytochemical cluster | No. 9 |
|---|---|
| KCF-S cluster | No. 2578 |
Link
ChEMBL
| By standard InChI | CHEMBL233632 |
|---|---|
| By standard InChI Main Layer | CHEMBL233632 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | D010658 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| asterids | 1 |
Family
| family name | count |
|---|---|
| Convolvulaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Pharbitis purpurea | 4119 | Convolvulaceae | asterids | Viridiplantae |
Human Protein / Gene in interaction
5 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL233632 |
CHEMBL1614458
(1)
|
0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | CHEMBL233632 |
CHEMBL1613808
(1)
|
0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | CHEMBL233632 |
CHEMBL2114842
(1)
|
0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL233632 |
CHEMBL2114890
(1)
|
0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | CHEMBL233632 |
CHEMBL1614364
(1)
|
1 / 1 |
CTD interaction (5)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D010658 | 10327 |
AKR1A1
ALDR1 ALR ARM DD3 |
aldo-keto reductase family 1, member A1 (aldehyde reductase) (EC:1.1.1.2) | AKR1A1 protein results in increased reduction of Phenylglyoxal |
increases reduction
|
protein |
10510318
|
| D010658 | 231 |
AKR1B1
ADR ALDR1 ALR2 AR |
aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) | AKR1B1 protein results in increased reduction of Phenylglyoxal |
increases reduction
|
protein |
10510318
|
| D010658 | 2530 |
FUT8
|
fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (EC:2.4.1.68) | Fucose analog inhibits the reaction [Phenylglyoxal results in decreased activity of FUT8 protein] |
decreases activity
/ decreases reaction |
protein |
12770769
|
| D010658 | 2530 |
FUT8
|
fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (EC:2.4.1.68) | Guanosine Diphosphate inhibits the reaction [Phenylglyoxal results in decreased activity of FUT8 protein] |
decreases activity
/ decreases reaction |
protein |
12770769
|
| D010658 | 2530 |
FUT8
|
fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (EC:2.4.1.68) | Phenylglyoxal results in decreased activity of FUT8 protein |
decreases activity
|
protein |
12770769
|