Carica papaya
Species
KNApSAcK Entry
| Organism name | Carica papaya |
|---|---|
| Genus | Carica |
| Family | Caricaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Carica papaya |
|---|---|
| Linked NCBI taxonomy ID | 3649 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Caricaceae |
|---|---|
| ID | 3647 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Natural Activity
List (122)
| Species | Activity |
|---|---|
| Carica papaya L. | Abortifacient |
| Carica papaya L. | Abortifacient |
| Carica papaya L. | Allergenic |
| Carica papaya L. | Allergenic |
| Carica papaya L. | Alterative |
| Carica papaya L. | Amebicide |
| Carica papaya L. | Amebicide |
| Carica papaya L. | Analgesic |
| Carica papaya L. | Analgesic |
| Carica papaya L. | Anthelmintic |
| Carica papaya L. | Antiaggregant |
| Carica papaya L. | Antibacterial |
| Carica papaya L. | Anticoagulant |
| Carica papaya L. | Anticonvulsant |
| Carica papaya L. | Anticonvulsant |
| Carica papaya L. | Antidiabetic |
| Carica papaya L. | Antidiphtheric |
| Carica papaya L. | Antidiptheric |
| Carica papaya L. | Antiedemic |
| Carica papaya L. | Antiedemic |
| Carica papaya L. | Antifertility |
| Carica papaya L. | Antifertility |
| Carica papaya L. | Antihypertensive |
| Carica papaya L. | Antiimplantation |
| Carica papaya L. | Antiimplantation |
| Carica papaya L. | Antiinflammatory |
| Carica papaya L. | Antiinflammatory |
| Carica papaya L. | Antioxidant |
| Carica papaya L. | Antioxidant |
| Carica papaya L. | Antipyretic |
| Carica papaya L. | Antiseptic |
| Carica papaya L. | Antiseptic |
| Carica papaya L. | Antispasmodic |
| Carica papaya L. | Antispasmodic |
| Carica papaya L. | Antitetanic |
| Carica papaya L. | Antitetanic |
| Carica papaya L. | Antitumor |
| Carica papaya L. | Antitumor |
| Carica papaya L. | Antiulcer |
| Carica papaya L. | Antiulcer |
| Carica papaya L. | Ascaricide |
| Carica papaya L. | Ascaricide |
| Carica papaya L. | Bactericide |
| Carica papaya L. | Bronchodilator |
| Carica papaya L. | Bronchodilator |
| Carica papaya L. | Candidicide |
| Carica papaya L. | Candidicide |
| Carica papaya L. | Cardiac |
| Carica papaya L. | Cardiac |
| Carica papaya L. | Cardiodepressant |
| Carica papaya L. | Cardiodepressant |
| Carica papaya L. | Cardiotonic |
| Carica papaya L. | Cardiotonic |
| Carica papaya L. | Carminative |
| Carica papaya L. | Carminative |
| Carica papaya L. | Cholagogue |
| Carica papaya L. | Chronotropic |
| Carica papaya L. | Chronotropic |
| Carica papaya L. | Cicatrizant |
| Carica papaya L. | Cicatrizant |
| Carica papaya L. | Contraceptive |
| Carica papaya L. | Contraceptive |
| Carica papaya L. | Depurative |
| Carica papaya L. | Digestive |
| Carica papaya L. | Digestive |
| Carica papaya L. | Diuretic |
| Carica papaya L. | Diuretic |
| Carica papaya L. | Ecbolic |
| Carica papaya L. | Embryotoxic |
| Carica papaya L. | Embryotoxic |
| Carica papaya L. | Emmenagogue |
| Carica papaya L. | Emmenagogue |
| Carica papaya L. | Enterodepressant |
| Carica papaya L. | Expectorant |
| Carica papaya L. | Febrifuge |
| Carica papaya L. | Fibrinolytic |
| Carica papaya L. | Fibrinolytic |
| Carica papaya L. | Fungicide |
| Carica papaya L. | Fungicide |
| Carica papaya L. | Gram(-)-icide |
| Carica papaya L. | Gram(+)-icide |
| Carica papaya L. | Hepatoprotective |
| Carica papaya L. | Histaminic |
| Carica papaya L. | Hypotensive |
| Carica papaya L. | Hypotensive |
| Carica papaya L. | IL-6-Inducer |
| Carica papaya L. | Immunostimulant |
| Carica papaya L. | Immunostimulant |
| Carica papaya L. | Lactagogue |
| Carica papaya L. | Laxative |
| Carica papaya L. | Laxative |
| Carica papaya L. | Molluscacide |
| Carica papaya L. | Myorelaxant |
| Carica papaya L. | Myorelaxant |
| Carica papaya L. | Nematocide |
| Carica papaya L. | Orexigenic |
| Carica papaya L. | Oxytocic |
| Carica papaya L. | Pectoral |
| Carica papaya L. | Pectoral |
| Carica papaya L. | Proteolytic |
| Carica papaya L. | Proteolytic |
| Carica papaya L. | Purgative |
| Carica papaya L. | Rubefacient |
| Carica papaya L. | Sedative |
| Carica papaya L. | Sedative |
| Carica papaya L. | Sterilant |
| Carica papaya L. | Stomachic |
| Carica papaya L. | Taenicide |
| Carica papaya L. | Taniacide |
| Carica papaya L. | Teratogenic |
| Carica papaya L. | Teratogenic |
| Carica papaya L. | Tranquilizer |
| Carica papaya L. | Tranquilizer |
| Carica papaya L. | Uterocontractant |
| Carica papaya L. | Uterorelaxant |
| Carica papaya L. | Uterorelaxant |
| Carica papaya L. | Vasoconstrictor |
| Carica papaya L. | Vasorelaxant |
| Carica papaya L. | Vermifuge |
| Carica papaya L. | Vermifuge |
| Carica papaya L. | Vulnerary |
| Carica papaya L. | Vulnerary |
Metabolite list (12)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00000920
|
beta-Cryptoxanthin
|
C010564
|
No. 26 | No. 59 |
|
|||
|
C00000035
|
GA35
/ Gibberellin A35 |
No. 40 | No. 41 |
|
||||
|
C00000003
|
GA3
/ Gibberellin A3 |
CHEMBL513241
CHEMBL566653 CHEMBL1232952 CHEMBL1476967 CHEMBL1487394 |
C007842
|
10 / 18 / 17 | No. 40 | No. 41 |
|
|
|
C00000001
|
GA1
/ Gibberellin A1 |
C422660
|
No. 40 | No. 41 |
|
|||
|
C00000055
|
GA55
/ Gibberellin A55 |
No. 40 | No. 41 |
|
||||
|
C00003760
|
Antheraxanthin
/ (3R,5R,6S,3'R)-zeaxanthin 5,6-epoxide |
C031140
|
No. 114 | No. 59 |
|
|||
|
C00007346
|
Tropaeolin
/ Glucotropaeolin / Benzylglucosinolate |
C060321
|
No. 158 | No. 77 |
|
|||
|
C00002692
|
Danielone
|
C104098
|
No. 1180 |
|
||||
|
C00003767
|
5,6-epoxy-beta-Carotene
/ beta-Carotene 5,6-epoxide |
C073147
|
No. 1206 | No. 59 |
|
|||
|
C00003779
|
Mutatochrome
/ beta-carotene 5,8-epoxide |
C001792
|
No. 1206 | No. 59 |
|
|||
|
C00002026
|
Carpaine
|
C018479
|
No. 6575 | No. 1 |
|
|||
|
C00010859
|
Isopropylcyclohexane
|
C055969
|
No. 7759 |
|
Human Protein / Gene in interactions
10 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000003 | 1 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000003 | 11 / 10 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000003 | 0 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000003 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00000003 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000003 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000003 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000003 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000003 | 0 / 1 |
| P10275 | Androgen receptor | NR3C4 | C00000003 | 3 / 4 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (18)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
KEGG DISEASE (17)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|