| Organism name | Gibberella fujikuroi |
|---|---|
| Genus | Gibberella |
| Family | Nectriaceae |
| Kingdom | Fungi |
| Linked NCBI taxonomy name | Fusarium fujikuroi |
|---|---|
| Linked NCBI taxonomy ID | 5127 |
| Linked level | species |
| Family in NCBI taxonomy | Nectriaceae |
|---|---|
| ID | 110618 |
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00000001
|
GA1
/ Gibberellin A1 |
C422660
|
No. 40 | No. 41 |
|
|||
|
C00000003
|
GA3
/ Gibberellin A3 |
CHEMBL513241
CHEMBL566653 CHEMBL1232952 CHEMBL1476967 CHEMBL1487394 |
C007842
|
10 / 18 / 17 | No. 40 | No. 41 |
|
|
|
C00000004
|
GA4
/ Gibberellin A4 |
No. 40 | No. 41 |
|
||||
|
C00000009
|
GA9
/ Gibberellin A9 |
No. 40 | No. 41 |
|
||||
|
C00000011
|
GA11
/ Gibberellin A11 |
No. 40 | No. 41 |
|
||||
|
C00007332
|
GA120
/ Gibberellin A120 |
No. 40 | No. 41 |
|
||||
|
C00000015
|
GA15
/ Gibberellin A15 |
No. 40 | No. 41 |
|
||||
|
C00000016
|
GA16
/ Gibberellin A16 |
No. 40 | No. 41 |
|
||||
|
C00000020
|
GA20
/ Gibberellin A20 |
No. 40 | No. 41 |
|
||||
|
C00000866
|
2,3-DehydroGA9
|
No. 40 | No. 41 |
|
||||
|
C00000214
|
GA10
/ Gibberellin A10 |
No. 40 | No. 41 |
|
||||
|
C00000098
|
GA2
/ Gibberellin A2 |
No. 40 | No. 41 |
|
||||
|
C00000037
|
GA37
/ Gibberellin A37 |
No. 40 | No. 41 |
|
||||
|
C00000040
|
GA40
/ Gibberellin A40 |
No. 40 | No. 41 |
|
||||
|
C00000056
|
GA56
/ Gibberellin A56 |
No. 40 | No. 41 |
|
||||
|
C00000057
|
GA57
/ Gibberellin A57 |
No. 40 | No. 41 |
|
||||
|
C00000047
|
GA47
/ Gibberellin A47 |
No. 40 | No. 41 |
|
||||
|
C00000054
|
GA54
/ Gibberellin A54 |
No. 40 | No. 41 |
|
||||
|
C00000055
|
GA55
/ Gibberellin A55 |
No. 40 | No. 41 |
|
||||
|
C00000078
|
GA78
/ Gibberellin A78 |
No. 40 | No. 41 |
|
||||
|
C00003652
|
Ergosterol
/ Ergosta-5,7,22-trien-3beta-ol |
CHEMBL222608
CHEMBL1232562 CHEMBL1512075 CHEMBL1741735 CHEMBL1965225 |
D004875
|
12 / 14 / 11 | No. 111 | No. 11 |
|
|
|
C00023764
|
Ergosta-5,7,22,24(28)-tetraen-3beta-ol
|
No. 111 | No. 11 |
|
||||
|
C00007253
|
ent-Kaurene
/ ent-Kaur-16-ene / (-)-ent-Kaur-16-ene |
CHEMBL454740
|
No. 159 | No. 41 |
|
|||
|
C00000042
|
GA42
/ Gibberellin A42 |
No. 187 | No. 41 |
|
||||
|
C00000036
|
GA36
/ Gibberellin A36 |
No. 187 | No. 41 |
|
||||
|
C00000024
|
GA24
/ Gibberellin A24 |
C120176
|
No. 187 | No. 41 |
|
|||
|
C00000041
|
GA41
/ Gibberellin A41 |
No. 187 | No. 41 |
|
||||
|
C00000025
|
GA25
/ Gibberellin A25 |
No. 187 | No. 41 |
|
||||
|
C00000013
|
GA13
/ Gibberellin A13 |
No. 187 | No. 41 |
|
||||
|
C00003657
|
Lanosterol
/ Lanosta-8,24-dien-3beta-ol |
CHEMBL225111
CHEMBL465181 CHEMBL1397369 |
D007810
|
10 / 17 / 17 | 1 / 0 | No. 218 | No. 51 |
|
|
C00000218
|
Jasmonic acid
/ trans-Jasmonic acid / 3-Oxo-2-(2Z-pentenyl)cyclotentylacetic acid |
CHEMBL445499
CHEMBL449572 |
C011006
|
4 / 1 / 0 | No. 707 | No. 70 |
|
|
|
C00023761
|
Ergosta-5,7,9(11),22-tetraenol
/ (+)-Ergosta-5,7,9(11),22-tetraenol / Ergosta-5,7,9(11),22-tetraen-3beta-ol |
C010905
|
No. 768 |
|
||||
|
C00007333
|
7beta,18-dihydroxykaurenolide
|
No. 999 | No. 41 |
|
||||
|
C00000886
|
Gibberellin A12 aldehyde
|
C048463
|
No. 1235 | No. 41 |
|
|||
|
C00000881
|
Cunabic acid
/ ent-Kaurenoic acid / ent-Kaur-16-en-19-oic acid |
CHEMBL523791
CHEMBL480983 CHEMBL1076299 CHEMBL1968150 |
C051436
|
1 / 0 / 0 | No. 1235 | No. 41 |
|
|
|
C00007331
|
Gibberellin A14-aldehyde
|
No. 1235 | No. 41 |
|
||||
|
C00011527
|
Cyclonerodiol
|
C000539
|
No. 2642 |
|
||||
|
C00049242
|
O-Demethylanhydrofusarubin
|
No. 4024 |
|
|||||
|
C00000908
|
GGPP
/ Geranylgeranyl diphosphate / Geranylgeranyl pyrophosphate |
CHEMBL1160059
CHEMBL1160061 CHEMBL1229266 |
C002963
|
3 / 0 / 0 | 34 / 0 | No. 4178 | No. 38 |
|
|
C00000880
|
ent-CPP
/ ent-Copalyl diphosphate |
No. 4186 | No. 46 |
|
||||
|
C00049240
|
Norbikaverin
|
No. 5475 | No. 65 |
|
||||
|
C00002798
|
Bikaverin
|
CHEMBL373432
|
C000269
|
No. 5475 | No. 65 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000003 C00003652 C00003657 | 0 / 1 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003652 C00003657 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000003 C00003652 | 1 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000003 C00003652 | 1 / 1 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000003 C00003657 | 11 / 10 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003652 C00003657 | 4 / 3 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000003 C00003652 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003652 C00003657 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003652 C00003657 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003652 C00003657 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000003 C00003652 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000003 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000003 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000003 | 2 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000218 | 0 / 0 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000218 | 0 / 0 |
| Q16850 | Lanosterol 14-alpha demethylase | Cytochrome P450 51A1 | C00003657 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00003657 | 0 / 0 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000218 | 1 / 0 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000218 | 1 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00003652 | 5 / 1 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000881 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000003 | 3 / 4 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00003657 | 0 / 0 |
| P31939 | Bifunctional purine biosynthesis protein PURH | Enzyme | C00003652 | 1 / 1 |
| P49356 | Protein farnesyltransferase subunit beta | Enzyme | C00000908 | 0 / 0 |
| P49354 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Enzyme | C00000908 | 0 / 0 |
| P53609 | Geranylgeranyl transferase type-1 subunit beta | Enzyme | C00000908 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00000908
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000908
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00000908
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000908
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00000908
|
| 1277 | COL1A1, OI4 | collagen, type I, alpha 1 |
C00000908
|
| 1401 | CRP, PTX1 | C-reactive protein, pentraxin-related |
C00000908
|
| 1490 | CTGF, CCN2, HCS24, IGFBP8, NOV2 | connective tissue growth factor |
C00000908
|
| 2152 | F3, CD142, TF, TFA | coagulation factor III (thromboplastin, tissue factor) |
C00000908
|
| 9453 | GGPS1, GGPPS, GGPPS1 | geranylgeranyl diphosphate synthase 1 (EC:2.5.1.1 2.5.1.10 2.5.1.29) |
C00000908
|
| 3156 | HMGCR, LDLCQ3 | 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) |
C00000908
|
| 3265 | HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1 | Harvey rat sarcoma viral oncogene homolog |
C00000908
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00000908
|
| 3552 | IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 | interleukin 1, alpha |
C00000908
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00000908
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00000908
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00000908
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00000908
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00000908
|
| 4312 | MMP1, CLG, CLGN | matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) |
C00000908
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00000908
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00000908
|
| 8013 | NR4A3, CHN, CSMF, MINOR, NOR1, TEC | nuclear receptor subfamily 4, group A, member 3 |
C00000908
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00000908
|
| 5155 | PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis | platelet-derived growth factor beta polypeptide |
C00000908
|
| 5444 | PON1, ESA, MVCD5, PON | paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) |
C00000908
|
| 5879 | RAC1, Rac-1, TC-25, p21-Rac1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
C00000908
|
| 56729 | RETN, ADSF, FIZZ3, RETN1, RSTN, XCP1 | resistin |
C00000908
|
| 387 | RHOA, ARH12, ARHA, RHO12, RHOH12 | ras homolog family member A |
C00000908
|
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00000908
|
| 7040 | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta | transforming growth factor, beta 1 |
C00000908
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000908
|
| 8743 | TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL | tumor necrosis factor (ligand) superfamily, member 10 |
C00000908
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00000908
|
| 1593 | CYP27A1, CP27, CTX, CYP27 | cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15) |
C00003657
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #608688 | Aicar transformylase/imp cyclohydrolase deficiency |
P31939
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
|
| #606785 | Crigler-najjar syndrome, type ii |
P22309
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143500 | Gilbert syndrome |
P22309
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00966 | AICA-ribosiduria |
P31939
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|