Avena sativa
Species
KNApSAcK Entry
| Organism name | Avena sativa |
|---|---|
| Genus | Avena |
| Family | Poaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Avena sativa |
|---|---|
| Linked NCBI taxonomy ID | 4498 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Poaceae |
|---|---|
| ID | 4479 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Metabolite list (18)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006278
|
Isoswertisin 2''-O-rhamnoside
|
No. 1 | No. 15 |
|
||||
|
C00014062
|
Isoorientin 2''-O-arabinoside
|
No. 1 | No. 15 |
|
||||
|
C00014039
|
Isovitexin 2''-O-arabinoside
|
No. 1 | No. 15 |
|
||||
|
C00006250
|
Molludistin 2''-O-rhamnoside
|
No. 1 | No. 15 |
|
||||
|
C00006353
|
Isoswertisin 4'-O-rhamnoside
|
No. 1 | No. 15 |
|
||||
|
C00003565
|
Avenacoside B
|
No. 21 | No. 11 |
|
||||
|
C00003564
|
Avenacoside A
|
No. 21 | No. 11 |
|
||||
|
C00000003
|
GA3
/ Gibberellin A3 |
CHEMBL513241
CHEMBL566653 CHEMBL1232952 CHEMBL1476967 CHEMBL1487394 |
C007842
|
10 / 18 / 17 | No. 40 | No. 41 |
|
|
|
C00003656
|
Isofucosterol
|
CHEMBL519971
CHEMBL1836654 |
No. 53 | No. 11 |
|
|||
|
C00003645
|
29-Isofucosterol
|
No. 53 | No. 11 |
|
||||
|
C00003581
|
Nuatigenin
|
No. 171 | No. 11 |
|
||||
|
C00042924
|
Salcolin A
|
CHEMBL1224894
CHEMBL1797782 |
No. 338 |
|
||||
|
C00042925
|
Salcolin B
|
CHEMBL1224894
CHEMBL1797782 |
No. 338 |
|
||||
|
C00000445
|
Avenoleic acid
/ 15R-Hydroxylinoleic acid |
No. 367 | No. 68 |
|
||||
|
C00003502
|
Avenacin A-1
|
C091460
|
No. 2066 | No. 51 |
|
|||
|
C00003503
|
Avenacin B-2
|
No. 2066 | No. 51 |
|
||||
|
C00001527
|
Avenanthramide A
|
No. 5841 |
|
|||||
|
C00001431
|
Spermidine
|
CHEMBL19612
|
D013095
|
26 / 10 / 12 | 5 / 5 | No. 5867 |
|
Human Protein / Gene in interactions
31 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000003 C00001431 | 1 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000003 C00001431 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000003 C00001431 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000003 C00001431 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000003 C00001431 | 0 / 1 |
| O75496 | Geminin | Unclassified protein | C00000003 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001431 | 3 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00001431 | 1 / 2 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00001431 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00001431 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00001431 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00001431 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00001431 | 1 / 2 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001431 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000003 | 2 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000003 | 11 / 10 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00001431 | 0 / 0 |
| Q6QHF9 | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | Enzyme | C00001431 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000003 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00001431 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00001431 | 0 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001431 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001431 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00001431 | 0 / 0 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00001431 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000003 | 3 / 4 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00001431 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00001431 | 1 / 1 |
| P40225 | Thrombopoietin | Unclassified protein | C00001431 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001431 | 0 / 0 |
| Q9H015 | Solute carrier family 22 member 4 | Unclassified protein | C00001431 | 1 / 1 |
5 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 153 | ADRB1, ADRB1R, B1AR, BETA1AR, RHR | adrenoceptor beta 1 |
C00001431
|
| 154 | ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR | adrenoceptor beta 2, surface |
C00001431
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001431
|
| 486 | FXYD2, ATP1G1, HOMG2 | FXYD domain containing ion transport regulator 2 |
C00001431
|
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00001431
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (26)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #180300 | Rheumatoid arthritis; ra |
Q9H015
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
KEGG DISEASE (26)
| KEGG | name | UniProt |
|---|---|---|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00286 | Crohn's disease |
Q9H015
(related)
|