Mangifera indica

• Index
• Plant Species
• Metabolite list (24)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Mangifera indica
Genus	Mangifera
Family	Anacardiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Mangifera indica
Linked NCBI taxonomy ID	29780
Linked level	species

Family

Family in NCBI taxonomy	Anacardiaceae
ID	4011

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (24)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00006698	Myrtillin / Delphinidin 3-O-beta-D-glucopyranoside	CHEMBL518846				No. 2	No. 15
C00006680	Peonidin galactoside / Peonidin 3-galactoside / Peonidin 3-O-beta-D-galactopyranoside	CHEMBL1784263				No. 2	No. 15
C00006650	Cyanidin 3-arabinoside					No. 2	No. 15
C00006722	Petunidin 3-glucoside / Petunidin 3-O-beta-D-glucopyranoside	CHEMBL1784264	C455107			No. 2	No. 15
C00002962	Aphloiol / Mangiferin / 2-beta-D-Glucopyranosyl-1,3,6,7-tetrahydroxy xanthone	CHEMBL1329826	C013592	27 / 17 / 17	39 / 41	No. 22	No. 15
C00000945	Butin / 7,3',4'-Trihydroxyflavanone	CHEMBL451168	C051437			No. 25	No. 14
C00000029	GA29 / Gibberellin A29					No. 40	No. 41
C00000020	GA20 / Gibberellin A20					No. 40	No. 41
C00000003	GA3 / Gibberellin A3	CHEMBL513241 CHEMBL566653 CHEMBL1232952 CHEMBL1476967 CHEMBL1487394	C007842	10 / 18 / 17		No. 40	No. 41
C00000001	GA1 / Gibberellin A1		C422660			No. 40	No. 41
C00003787	Violaxanthin		C005613			No. 114	No. 59
C00048268	23-Hydroxy-mangiferonic acid	CHEMBL550926				No. 129	No. 11
C00000019	GA19 / Gibberellin A19		C120175			No. 187	No. 41
C00002445	Rubrofusarin	CHEMBL475086	C015497			No. 493	No. 65
C00000165	gamma-Eudesmol	CHEMBL477900				No. 613	No. 38
C00002662	5-Pentadecylresorcinol	CHEMBL98610		2 / 4 / 2		No. 652
C00002655	5-(Heptadec-12-enyl)resorcinol	CHEMBL1795548				No. 652
C00002416	Aurasperone D					No. 863	No. 65
C00000095	9-Ribosyl-cis-zeatin / 6-(4-Hydroxy-3-methyl-cis-2-butenylamino)-9-beta-D-ribofuranosylpurine					No. 989
C00000096	9-Ribosyl-trans-zeatin / Zeatin-9-beta-D-ribofuranoside					No. 989
C00003767	5,6-epoxy-beta-Carotene / beta-Carotene 5,6-epoxide		C073147			No. 1206	No. 59
C00000093	Dihydrozeatin					No. 2879
C00000094	2iP / N6-(delta2-Isopentenyl)adenine	CHEMBL476189	C001478	5 / 2 / 3	18 / 0	No. 2879
C00000091	trans-Zeatin	CHEMBL525239	D015026	2 / 3 / 2	0 / 1	No. 2879

Human Protein / Gene in interactions

39 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000003 C00000094	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000003 C00000094	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000003 C00000094	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000003 C00000094	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000003 C00002962	0 / 0
O75496	Geminin	Unclassified protein	C00000003 C00002962	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000003 C00000094	0 / 1
P10696	Alkaline phosphatase, placental-like	Enzyme	C00002962	0 / 1
P02545	Prelamin-A/C	Unclassified protein	C00000003	11 / 10
P00352	Retinal dehydrogenase 1	Enzyme	C00002962	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000003	2 / 0
Q9Y5X4	Photoreceptor-specific nuclear receptor	NR2E3	C00002962	2 / 2
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00002962	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00002962	1 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00002962	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00002962	3 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002962	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002962	0 / 0
P00734	Prothrombin	S1A	C00002662	4 / 2
P16473	Thyrotropin receptor	Glycohormone receptor	C00000091	3 / 2
P29466	Caspase-1	C14	C00002962	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002962	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002962	2 / 2
P55210	Caspase-7	C14	C00002962	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002962	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00002662	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00002962	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00002962	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002962	0 / 0
P10275	Androgen receptor	NR3C4	C00000003	3 / 4
Q9UBT6	DNA polymerase kappa	Enzyme	C00002962	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002962	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000091	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002962	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002962	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002962	1 / 4
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002962	5 / 3
Q9Y618	Nuclear receptor corepressor 2	Unclassified protein	C00002962	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002962	0 / 0

57 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
440	ASNS, TS11	asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4)	C00000094
694	BTG1	B-cell translocation gene 1, anti-proliferative	C00000094
10681	GNB5, GB5	guanine nucleotide binding protein (G protein), beta 5	C00000094
182	JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1	jagged 1	C00000094
9818	NUPL1, PRO2463	nucleoporin like 1	C00000094
5142	PDE4B, DPDE4, PDE4B5, PDEIVB	phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17)	C00000094
8544	PIR	pirin (iron-binding nuclear protein) (EC:1.13.11.24)	C00000094
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00000094
9360	PPIG, CARS-Cyp, CYP, SCAF10, SRCyp	peptidylprolyl isomerase G (cyclophilin G) (EC:5.2.1.8)	C00000094
5782	PTPN12, PTP-PEST, PTPG1	protein tyrosine phosphatase, non-receptor type 12 (EC:3.1.3.48)	C00000094
5774	PTPN3, PTP-H1, PTPH1	protein tyrosine phosphatase, non-receptor type 3 (EC:3.1.3.48)	C00000094
6004	RGS16, A28-RGS14, A28-RGS14P, RGS-R	regulator of G-protein signaling 16	C00000094
6016	RIT1, NS8, RIBB, RIT, ROC1	Ras-like without CAAX 1	C00000094
6286	S100P, MIG9	S100 calcium binding protein P	C00000094
7029	TFDP2, DP2	transcription factor Dp-2 (E2F dimerization partner 2)	C00000094
7127	TNFAIP2, B94, EXOC3L3	tumor necrosis factor, alpha-induced protein 2	C00000094
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000094
7431	VIM, CTRCT30	vimentin	C00000094
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002962
25	ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl	c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2)	C00002962
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00002962
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00002962
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00002962
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002962
847	CAT	catalase (EC:1.11.1.6)	C00002962
891	CCNB1, CCNB	cyclin B1	C00002962
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00002962
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00002962
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00002962
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002962
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002962
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00002962
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00002962
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00002962
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00002962
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00002962
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002962
3551	IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)	C00002962
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002962
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002962
4023	LPL, HDLCQ11, LIPD	lipoprotein lipase (EC:3.1.1.34)	C00002962
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00002962
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00002962
4793	NFKBIB, IKBB, TRIP9	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	C00002962
4803	NGF, Beta-NGF, HSAN5, NGFB	nerve growth factor (beta polypeptide)	C00002962
5320	PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2	phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4)	C00002962
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00002962
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002962
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002962
6716	SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22)	C00002962
7015	TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT	telomerase reverse transcriptase (EC:2.7.7.49)	C00002962
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002962
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00002962
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002962
7364	UGT2B7, UDPGT_2B9, UDPGT2B7, UDPGTH2, UGT2B9	UDP glucuronosyltransferase 2 family, polypeptide B7 (EC:2.4.1.17)	C00002962
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00002962
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00002962

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions