Malus pumila
Species
KNApSAcK Entry
| Organism name | Malus pumila |
|---|---|
| Genus | Malus |
| Family | Rosaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Malus pumila |
|---|---|
| Linked NCBI taxonomy ID | 283210 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Rosaceae |
|---|---|
| ID | 3745 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006651
|
Cyanidin 3-xyloside
|
No. 2 | No. 15 |
|
||||
|
C00009090
|
Epicatechin-(4beta->8)-epicatechin-(4beta->6)-epicatechin
|
CHEMBL592329
|
2 / 3 / 4 | No. 29 | No. 19 |
|
||
|
C00000100
|
IAA
/ Indole-3-acetic acid |
CHEMBL82411
|
C030737
|
3 / 0 / 0 | 2 / 1 | No. 1432 | No. 4 |
|
|
C00000134
|
(s)-(+)-Abscisic acid
/ 2,4-Pentadienoic acid |
CHEMBL288040
CHEMBL379808 CHEMBL1318134 CHEMBL1469719 CHEMBL1741460 CHEMBL1965138 |
D000040
|
10 / 9 / 10 | No. 1435 | No. 38 |
|
|
|
C00000101
|
IAA methyl ester
/ Methyl indole-3-acetate |
No. 4225 |
|
|||||
|
C00000175
|
Ethylene
|
CHEMBL117822
|
C036216
|
No. 8854 |
|
Human Protein / Gene in interactions
15 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000134 | 1 / 0 |
| Q16773 | Kynurenine--oxoglutarate transaminase 1 | Enzyme | C00000100 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00009090 | 2 / 2 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000134 | 3 / 2 |
| P02768 | Serum albumin | Secreted protein | C00000100 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000134 | 0 / 1 |
| P10145 | Interleukin-8 | Secreted protein | C00000134 | 0 / 0 |
| Q9HBH1 | Peptide deformylase, mitochondrial | Enzyme | C00000100 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000134 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00009090 | 1 / 3 |
| P03372 | Estrogen receptor | NR3A1 | C00000134 | 1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000134 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000134 | 0 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000134 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000134 | 3 / 4 |
2 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000100
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00000100
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (12)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
KEGG DISEASE (14)
| KEGG | name | UniProt |
|---|---|---|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00025 | Penile cancer |
P08253
(related)
P14780 (related) |
| H00028 | Choriocarcinoma |
P08253
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|