Derris oblonga

• Index
• Plant Species
• Metabolite list (24)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Derris oblonga
Genus	Derris
Family	Fabaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Derris
Linked NCBI taxonomy ID	53864
Linked level	genus

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (24)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00019418	Oblonginol / 5,7,5'-Trihydroxy-4'-methoxycoumaronochromone					No. 3	No. 15
C00019417	Oblongin / Desmoxyphyllin B					No. 3	No. 15
C00002525	Formononetin / 7-Hydroxy-4'-methoxyisoflavone	CHEMBL242341	C007768	24 / 36 / 58	13 / 0	No. 3	No. 15
C00003738	beta-Amyrin / beta-Amirin / beta-Amyrine / beta-Amyrenol		C036380		0 / 4	No. 23	No. 51
C00003749	Lupeol / Lupenol / (+)-Lupenol	CHEMBL289191 CHEMBL459702	C010480	3 / 0 / 0	2 / 6	No. 23	No. 51
C00019220	Lupenone	CHEMBL486393 CHEMBL575188		3 / 4 / 2		No. 23	No. 51
C00019421	6-Oxo-6a,12a-dehydro-alpha-toxicarol					No. 24	No. 15
C00009601	Dehydrodeguelin / 6a,12a-Dehydrodeguelin	CHEMBL465673				No. 24	No. 15
C00009986	6-Hydroxy-6a,12a-dehydro-alpha-toxicarol					No. 24	No. 15
C00009605	Dehydrotoxicarol / 7a,13a-Didehydrotoxicarol	CHEMBL122787				No. 24	No. 15
C00009517	Toxicarolisoflavone					No. 24	No. 15
C00019420	Physcion / 1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone	CHEMBL42624	C008905	18 / 20 / 14	1 / 0	No. 41	No. 62
C00000555	Emodin	CHEMBL289277	D004642	109 / 88 / 91	68 / 9	No. 41	No. 62
C00009763	8-Methoxycoumestrol / 3'-Methoxycoumestrol / 7,12-Dihydroxy-11-methoxycoumestan					No. 54	No. 17
C00019173	(+)-Maackiain / 3-Hydroxy-8,9-(methylenedioxy)pterocarpan	CHEMBL334918 CHEMBL239047 CHEMBL445279		3 / 2 / 3		No. 66	No. 15
C00019419	Derricarpin					No. 66	No. 15
C00009380	Daidzein / 7,4'-Dihydroxyisoflavone	CHEMBL8145	C004742	60 / 68 / 76	113 / 12	No. 71	No. 15
C00009602	Dehydrorotenone / Didehydrorotenone / 6a,12a-Dehydrorotenone	CHEMBL7940				No. 236	No. 15
C00009606	Villosol / 6a,12-Didehydrosumatrol / 6a,12a-Dehydro-alpha-toxicarol		C048348			No. 236	No. 15
C00002575	Sumatrol	CHEMBL518045				No. 281	No. 15
C00002537	Rotenolone / 12a-Hydroxyrotenone	CHEMBL240545				No. 281	No. 15
C00002578	Tephrosin	CHEMBL241806	C480848		6 / 0	No. 589	No. 15
C00009591	11-Hydroxytephrosin	CHEMBL419669				No. 589	No. 15
C00001151	Sucrose / (+)-Sucrose	CHEMBL253582 CHEMBL1976550	D013395	1 / 0 / 0	4 / 10	No. 3949

Human Protein / Gene in interactions

151 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P00352	Retinal dehydrogenase 1	Enzyme	C00000555 C00002525 C00009380 C00019420	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000555 C00002525 C00009380 C00019420	4 / 3
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000555 C00002525 C00009380 C00019173	0 / 1
P03372	Estrogen receptor	NR3A1	C00000555 C00009380 C00019420	1 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000555 C00002525 C00009380	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002525 C00009380 C00019420	2 / 2
P04637	Cellular tumor antigen p53	Transcription Factor	C00000555 C00002525 C00009380	7 / 37
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000555 C00002525 C00009380	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000555 C00002525 C00009380	1 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000555 C00002525 C00009380	5 / 3
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002525 C00009380 C00019420	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000555 C00009380 C00019420	0 / 1
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000555 C00002525 C00009380	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000555 C00002525 C00009380	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000555 C00002525 C00009380	1 / 0
P40225	Thrombopoietin	Unclassified protein	C00000555 C00009380	1 / 1
P08246	Neutrophil elastase	S1A	C00000555 C00019420	2 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00000555 C00019420	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00000555 C00009380	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000555 C00019420	0 / 1
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00002525 C00009380	0 / 0
P10275	Androgen receptor	NR3C4	C00000555 C00009380	3 / 4
O43451	Maltase-glucoamylase, intestinal	Hydrolase	C00000555 C00019420	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00000555 C00009380	2 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000555 C00009380	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000555 C00009380	1 / 1
O00255	Menin	Unclassified protein	C00000555 C00002525	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000555 C00002525	1 / 2
P02545	Prelamin-A/C	Unclassified protein	C00000555 C00009380	11 / 10
Q16637	Survival motor neuron protein	Unclassified protein	C00002525 C00009380	4 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000555 C00019420	0 / 0
P31639	Sodium/glucose cotransporter 2	Glucose	C00002525 C00019173	1 / 1
P10828	Thyroid hormone receptor beta	NR1A2	C00000555 C00009380	3 / 1
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000555 C00009380	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00000555 C00009380	1 / 1
P13866	Sodium/glucose cotransporter 1	Glucose	C00002525 C00019173	1 / 1
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000555 C00009380	3 / 0
Q96RI1	Bile acid receptor	NR1H4	C00000555 C00019220	0 / 0
Q9H244	P2Y purinoceptor 12	Purine receptor	C00000555 C00019420	1 / 1
P33527	Multidrug resistance-associated protein 1	drugs	C00002525 C00009380	0 / 0
P09619	Platelet-derived growth factor receptor beta	Pdgfr	C00000555 C00019420	5 / 1
P54132	Bloom syndrome protein	Enzyme	C00000555 C00009380	1 / 2
P04150	Glucocorticoid receptor	NR3C1	C00000555 C00009380	0 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000555 C00019420	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00002525 C00009380	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00003749 C00009380	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003749 C00009380	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000555 C00019420	2 / 3
P08311	Cathepsin G	S1A	C00000555 C00019420	0 / 0
P16234	Platelet-derived growth factor receptor alpha	Pdgfr	C00000555 C00019420	2 / 1
O75496	Geminin	Unclassified protein	C00000555 C00009380	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000555 C00009380	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00009380	2 / 2
P09769	Tyrosine-protein kinase Fgr	Src	C00000555	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00000555	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00000555	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00009380	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000555	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00002525	4 / 2
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00000555	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00009380	0 / 0
O75582	Ribosomal protein S6 kinase alpha-5	CAMK serine/threonine protein kinase MSKB subfamily	C00000555	0 / 0
P10145	Interleukin-8	Secreted protein	C00000555	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00000555	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00009380	0 / 0
Q15418	Ribosomal protein S6 kinase alpha-1	Rskb	C00000555	0 / 0
O15264	Mitogen-activated protein kinase 13	p38	C00000555	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000555	1 / 1
P11308	Transcriptional regulator ERG	Unclassified protein	C00000555	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00000555	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00000555	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00009380	1 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00009380	1 / 8
P15311	Ezrin	Unclassified protein	C00000555	0 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00000555	1 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00000555	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00019220	4 / 2
P23443	Ribosomal protein S6 kinase beta-1	p70	C00000555	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00000555	0 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00000555	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00019420	1 / 1
P04745	Alpha-amylase 1	Enzyme	C00009380	0 / 0
P49137	MAP kinase-activated protein kinase 2	CAMK serine/threonine protein kinase MAPKAPK	C00000555	0 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00002525	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000555	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00009380	0 / 0
Q9Y4K4	Mitogen-activated protein kinase kinase kinase kinase 5	STE serine/threonine protein kinase KHS subfamily	C00000555	0 / 0
P02768	Serum albumin	Secreted protein	C00001151	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00009380	2 / 0
P05091	Aldehyde dehydrogenase, mitochondrial	Oxidoreductase	C00009380	1 / 1
P68400	Casein kinase II subunit alpha	Ck2	C00000555	0 / 0
Q01453	Peripheral myelin protein 22	Unclassified protein	C00009380	5 / 2
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00000555	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00009380	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000555	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00009380	1 / 1
P35372	Mu-type opioid receptor	Opioid receptor	C00009380	0 / 0
Q8IW41	MAP kinase-activated protein kinase 5	CAMK serine/threonine protein kinase MAPKAPK	C00000555	0 / 0
O75116	Rho-associated protein kinase 2	Rock	C00000555	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00009380	0 / 0
P07948	Tyrosine-protein kinase Lyn	Src	C00000555	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000555	3 / 2
P31749	RAC-alpha serine/threonine-protein kinase	Akt	C00000555	4 / 1
O00141	Serine/threonine-protein kinase Sgk1	AGC serine/threonine protein kinase SGK subfamily	C00000555	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003749	0 / 0
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00009380	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00019220	0 / 0
O75365	Protein tyrosine phosphatase type IVA 3	Tyr	C00000555	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00000555	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00000555	0 / 0
O14757	Serine/threonine-protein kinase Chk1	Chk1	C00000555	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000555	5 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00000555	0 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00000555	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000555	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000555	0 / 0
P42336	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Enzyme	C00000555	9 / 1
P41240	Tyrosine-protein kinase CSK	Csk	C00000555	0 / 0
O15530	3-phosphoinositide-dependent protein kinase 1	Pdk1	C00000555	0 / 0
P06746	DNA polymerase beta	Enzyme	C00000555	0 / 0
P54646	5'-AMP-activated protein kinase catalytic subunit alpha-2	Ampk	C00000555	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000555	0 / 0
P43405	Tyrosine-protein kinase SYK	Syk	C00000555	0 / 0
Q13627	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	CMGC dual-specificity kinase DYRK1	C00000555	1 / 0
P53778	Mitogen-activated protein kinase 12	p38	C00000555	0 / 0
Q15759	Mitogen-activated protein kinase 11	p38	C00000555	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000555	2 / 2
P14618	Pyruvate kinase PKM	Enzyme	C00009380	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00009380	1 / 1
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000555	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00009380	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00009380	1 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00000555	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00000555	1 / 4
P45983	Mitogen-activated protein kinase 8	Jnk	C00000555	0 / 0
P53779	Mitogen-activated protein kinase 10	Jnk	C00000555	0 / 1
P45984	Mitogen-activated protein kinase 9	Jnk	C00000555	0 / 0
P22694	cAMP-dependent protein kinase catalytic subunit beta	Pka	C00000555	0 / 0
P17612	cAMP-dependent protein kinase catalytic subunit alpha	Pka	C00000555	0 / 0
P22612	cAMP-dependent protein kinase catalytic subunit gamma	Pka	C00000555	0 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00009380	0 / 0
Q02750	Dual specificity mitogen-activated protein kinase kinase 1	Ste7	C00000555	1 / 1
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00009380	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00009380	1 / 1
Q9HCP0	Casein kinase I isoform gamma-1	Ck1	C00000555	0 / 0
P48730	Casein kinase I isoform delta	Ck1	C00000555	1 / 0
P49674	Casein kinase I isoform epsilon	Ck1	C00000555	0 / 0
P78368	Casein kinase I isoform gamma-2	Ck1	C00000555	0 / 0
P48729	Casein kinase I isoform alpha	Ck1	C00000555	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002525	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00009380	0 / 0

183 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000555 C00002525 C00009380
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000555 C00002525 C00009380
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00000555 C00002525 C00009380
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000555 C00002525 C00009380
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000555 C00002525 C00009380
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000555 C00002525 C00009380
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000555 C00002525 C00009380
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000555 C00002525 C00009380
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000555 C00002525 C00009380
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00002525 C00009380
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002578 C00009380
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00000555 C00009380
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00000555 C00009380
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000555 C00002578
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00000555 C00009380
3337	DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1	DnaJ (Hsp40) homolog, subfamily B, member 1	C00000555
103993			C00009380
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00009380
890	CCNA2, CCN1, CCNA	cyclin A2	C00009380
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00009380
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00009380
632	BGLAP, BGP, OC, OCN	bone gamma-carboxyglutamate (gla) protein	C00009380
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00009380
1103	CHAT, CHOACTASE, CMS1A, CMS1A2	choline O-acetyltransferase (EC:2.3.1.6)	C00009380
1152	CKB, B-CK, CKBB	creatine kinase, brain (EC:2.7.3.2)	C00009380
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00009380
9167	COX7A2L, COX7AR, COX7RP, EB1, SIG81	cytochrome c oxidase subunit VIIa polypeptide 2 like	C00009380
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00009380
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00009380
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00009380
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00009380
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00009380
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00009380
1589	CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B	cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10)	C00009380
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00009380
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00009380
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00009380
1795	DOCK3, MOCA, PBP	dedicator of cytokinesis 3	C00009380
1846	DUSP4, HVH2, MKP-2, MKP2, TYP	dual specificity phosphatase 4 (EC:3.1.3.16 3.1.3.48)	C00009380
9166	EBAG9, EB9, PDAF	estrogen receptor binding site associated, antigen, 9	C00009380
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00009380
2027	ENO3, GSD13, MSE	enolase 3 (beta, muscle) (EC:4.2.1.11)	C00009380
2041	EPHA1, EPH, EPHT, EPHT1	EPH receptor A1 (EC:2.7.10.1)	C00009380
83715	ESPN, DFNB36	espin	C00009380
11177	BAZ1A, ACF1, WALp1, WCRF180, hACF1	bromodomain adjacent to zinc finger domain, 1A	C00009380
23545	ATP6V0A2, A2, ARCL, ARCL2A, ATP6A2, ATP6N1D, J6B7, RTF, STV1, TJ6, TJ6M, TJ6S, VPH1, WSS	ATPase, H+ transporting, lysosomal V0 subunit a2 (EC:3.6.3.6)	C00009380
2101	ESRRA, ERR1, ERRa, ERRalpha, ESRL1, NR3B1	estrogen-related receptor alpha	C00009380
2103	ESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2	estrogen-related receptor beta	C00009380
2104	ESRRG, ERR3, ERRgamma, NR3B3	estrogen-related receptor gamma	C00009380
56776	FMN2	formin 2	C00009380
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00009380
9687	GREB1	growth regulation by estrogen in breast cancer 1	C00009380
3284	HSD3B2, HSD3B, HSDB, SDR11E2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1)	C00009380
7866	IFRD2, IFNRP, SKMc15, SM15	interferon-related developmental regulator 2	C00009380
3480	IGF1R, CD221, IGFIR, IGFR, JTK13	insulin-like growth factor 1 receptor (EC:2.7.10.1)	C00009380
3487	IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4	insulin-like growth factor binding protein 4	C00009380
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00009380
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00009380
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00009380
26145	IRF2BP1	interferon regulatory factor 2 binding protein 1	C00009380
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00009380
26251	KCNG2, KCNF2, KV6.2	potassium voltage-gated channel, subfamily G, member 2	C00009380
354	KLK3, APS, KLK2A1, PSA, hK3	kallikrein-related peptidase 3 (EC:3.4.21.77)	C00009380
27074	LAMP3, CD208, DC_LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403	lysosomal-associated membrane protein 3	C00009380
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00009380
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00009380
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00009380
4502	MT2A, MT2	metallothionein 2A	C00009380
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00009380
10499	NCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75	nuclear receptor coactivator 2	C00009380
4824	NKX3-1, BAPX2, NKX3, NKX3.1, NKX3A	NK3 homeobox 1	C00009380
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00009380
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00009380
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00009380
8204	NRIP1, RIP140	nuclear receptor interacting protein 1	C00009380
56944	OLFML3, HNOEL-iso, OLF44	olfactomedin-like 3	C00009380
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00009380
5111	PCNA	proliferating cell nuclear antigen	C00009380
64236	PDLIM2, MYSTIQUE, SLIM	PDZ and LIM domain 2 (mystique)	C00009380
5174	PDZK1, CAP70, CLAMP, NHERF-3, NHERF3, PDZD1	PDZ domain containing 1	C00009380
5241	PGR, NR3C3, PR	progesterone receptor	C00009380
5411	PNN, DRS, DRSP, SDK3, memA	pinin, desmosome associated protein	C00009380
10957	PNRC1, B4-2, PNAS-145, PROL2, PRR2	proline-rich nuclear receptor coactivator 1	C00009380
5458	POU4F2, BRN3.2, BRN3B, Brn-3b	POU class 4 homeobox 2	C00009380
396	ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1	Rho GDP dissociation inhibitor (GDI) alpha	C00009380
11098	PRSS23, SIG13, SPUVE, ZSIG13	protease, serine, 23	C00009380
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00009380
5747	PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK	protein tyrosine kinase 2 (EC:2.7.10.2)	C00009380
5932	RBBP8, COM1, CTIP, JWDS, RIM, SAE2, SCKL2	retinoblastoma binding protein 8	C00009380
6197	RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2	ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1)	C00009380
81537	SGPP1, SPPase1	sphingosine-1-phosphate phosphatase 1	C00009380
6558	SLC12A2, BSC, BSC2, NKCC1	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	C00009380
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00009380
8140	SLC7A5, 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1	solute carrier family 7 (amino acid transporter light chain, L system), member 5	C00009380
6781	STC1, STC	stanniocalcin 1	C00009380
27347	STK39, DCHT, PASK, SPAK	serine threonine kinase 39 (EC:2.7.11.1)	C00009380
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00009380
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00009380
6870	TACR3, HH11, NK-3R, NK3R, NKR, TAC3RL	tachykinin receptor 3	C00009380
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00009380
7041	TGFB1I1, ARA55, HIC-5, HIC5, TSC-5	transforming growth factor beta 1 induced transcript 1	C00009380
7130	TNFAIP6, TSG-6, TSG6	tumor necrosis factor, alpha-induced protein 6	C00009380
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00009380
9537	TP53I11, PIG11	tumor protein p53 inducible protein 11	C00009380
7164	TPD52L1, D53, hD53	tumor protein D52-like 1	C00009380
7345	UCHL1, NDGOA, PARK5, PGP_9.5, PGP9.5, PGP95, Uch-L1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (EC:3.4.19.12)	C00009380
251	ALPPL2, ALPG, ALPPL, GCAP	alkaline phosphatase, placental-like 2 (EC:3.1.3.1)	C00009380
249	ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP	alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1)	C00009380
119	ADD2, ADDB	adducin 2 (beta)	C00009380
10057	ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	C00009380
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00009380
7367	UGT2B17, BMND12, UDPGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17 (EC:2.4.1.17)	C00009380
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00009380
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002525
2056	EPO, EP, MVCD2	erythropoietin	C00002525
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00002525
581	BAX, BCL2L4	BCL2-associated X protein	C00019420
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00003749
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00003749
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00002578
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00002578
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00002578
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00002578
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00009380
58	ACTA1, ACTA, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3	actin, alpha 1, skeletal muscle	C00000555
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000555
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00000555
9529	BAG5, BAG-5	BCL2-associated athanogene 5	C00000555
51283	BFAR, BAR, RNF47	bifunctional apoptosis regulator	C00000555
821	CANX, CNX, IP90, P90	calnexin	C00000555
9133	CCNB2, HsT17299	cyclin B2	C00000555
8621	CDK13, CDC2L, CDC2L5, CHED, hCDK13	cyclin-dependent kinase 13 (EC:2.7.11.23 2.7.11.22)	C00000555
1951	CELSR3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2, RESDA1	cadherin, EGF LAG seven-pass G-type receptor 3	C00000555
10987	COPS5, CSN5, JAB1, MOV-34, SGN5	COP9 signalosome subunit 5	C00000555
1509	CTSD, CLN10, CPSD	cathepsin D (EC:3.4.23.5)	C00000555
1719	DHFR, DHFRP1, DYR	dihydrofolate reductase (EC:1.5.1.3)	C00000555
672	BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53	breast cancer 1, early onset	C00009380
1875	E2F5, E2F-5	E2F transcription factor 5, p130-binding	C00000555
9538	EI24, EPG4, PIG8, TP53I8	etoposide induced 2.4	C00000555
1967	EIF2B1, EIF2B, EIF2BA	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	C00000555
2308	FOXO1, FKH1, FKHR, FOXO1A	forkhead box O1	C00000555
2620	GAS2	growth arrest-specific 2	C00000555
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00000555
2947	GSTM3, GST5, GSTB, GSTM3-3, GTM3	glutathione S-transferase mu 3 (brain) (EC:2.5.1.18)	C00000555
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000555
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00000555
3440	IFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2	interferon, alpha 2	C00000555
3708	ITPR1, INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29	inositol 1,4,5-trisphosphate receptor, type 1	C00000555
3727	JUND, AP-1	jun D proto-oncogene	C00000555
3880	KRT19, CK19, K19, K1CS	keratin 19	C00000555
23499	MACF1, ABP620, ACF7, MACF, OFC4	microtubule-actin crosslinking factor 1	C00000555
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00000555
4137	MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU	microtubule-associated protein tau	C00000555
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00000555
5082	PDCL, PhLP	phosducin-like	C00000555
5289	PIK3C3, VPS34, hVps34	phosphatidylinositol 3-kinase, catalytic subunit type 3 (EC:2.7.1.137)	C00000555
8493	PPM1D, PP2C-DELTA, WIP1	protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16)	C00000555
9588	PRDX6, 1-Cys, AOP2, NSGPx, PRX, aiPLA2, p29	peroxiredoxin 6 (EC:1.11.1.9 1.11.1.15)	C00000555
51495	PTPLAD1, B-IND1, HACD3, HSPC121	protein tyrosine phosphatase-like A domain containing 1 (EC:4.2.1.134)	C00000555
5894	RAF1, CRAF, NS5, Raf-1, c-Raf	v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1)	C00000555
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000555
5955	RCN2, E6BP, ERC-55, ERC55, TCBP49	reticulocalbin 2, EF-hand calcium binding domain	C00000555
387	RHOA, ARH12, ARHA, RHO12, RHOH12	ras homolog family member A	C00000555
6093	ROCK1, P160ROCK, ROCK-I	Rho-associated, coiled-coil containing protein kinase 1 (EC:2.7.11.1)	C00000555
9475	ROCK2, ROCK-II	Rho-associated, coiled-coil containing protein kinase 2 (EC:2.7.11.1)	C00000555
10055	SAE1, AOS1, HSPC140, SUA1, UBLE1A	SUMO1 activating enzyme subunit 1	C00000555
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00000555
6489	ST8SIA1, GD3S, SIAT8, SIAT8-A, SIAT8A, ST8SiaI	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (EC:2.4.99.8)	C00000555
10963	STIP1, HOP, IEF-SSP-3521, P60, STI1, STI1L	stress-induced-phosphoprotein 1	C00000555
55578	SUPT20H, C13, C13orf19, FAM48A, P38IP, SPT20	suppressor of Ty 20 homolog (S. cerevisiae)	C00000555
51347	TAOK3, DPK, JIK, MAP3K18	TAO kinase 3 (EC:2.7.11.1)	C00000555
6903	TBCC, CFC	tubulin folding cofactor C	C00000555
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00000555
7186	TRAF2, MGC:45012, TRAP, TRAP3	TNF receptor-associated factor 2	C00000555
10381	TUBB3, CDCBM, CDCBM1, CFEOM3A, TUBB4, beta-4	tubulin, beta 3 class III	C00000555
54957	TXNL4B, DLP, Dim2	thioredoxin-like 4B	C00000555
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000555
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00000555
7416	VDAC1, PORIN, VDAC-1	voltage-dependent anion channel 1	C00000555
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00001151
55630	SLC39A4, AEZ, AWMS2, ZIP4	solute carrier family 39 (zinc transporter), member 4	C00001151
80834	TAS1R2, GPR71, T1R2, TR2	taste receptor, type 1, member 2	C00001151
83756	TAS1R3, T1R3	taste receptor, type 1, member 3	C00001151

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