Acer saccharum
Species
KNApSAcK Entry
| Organism name | Acer saccharum |
|---|---|
| Genus | Acer |
| Family | Sapindaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Acer saccharum |
|---|---|
| Linked NCBI taxonomy ID | 4024 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Aceraceae |
|---|---|
| ID | 910345 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006798
|
Cyanidin 3-(2''-galloylglucoside)
|
No. 98 |
|
|||||
|
C00002775
|
Sinapaldehyde
/ Sinapic aldehyde |
CHEMBL225067
|
C075386
|
No. 310 | No. 6 |
|
||
|
C00002728
|
Coniferaldehyde
/ Coniferyl aldehyde / 4-Hydroxy-3-methoxycinnamaldehyde |
CHEMBL242529
CHEMBL1956165 |
C075384
|
1 / 1 / 1 | No. 310 | No. 6 |
|
|
|
C00001411
|
Gramine
|
CHEMBL254348
|
C007884
|
13 / 11 / 15 | No. 1385 | No. 4 |
|
|
|
C00001151
|
Sucrose
/ (+)-Sucrose |
CHEMBL253582
CHEMBL1976550 |
D013395
|
1 / 0 / 0 | 4 / 10 | No. 3949 |
|
Human Protein / Gene in interactions
15 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001411 | 1 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001411 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001411 | 3 / 2 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00002728 | 1 / 1 |
| P02768 | Serum albumin | Secreted protein | C00001151 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001411 | 0 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001411 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001411 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001411 | 3 / 3 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001411 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001411 | 0 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001411 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001411 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00001411 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001411 | 1 / 2 |
4 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 3630 | INS, IDDM2, ILPR, IRDN, MODY10 | insulin |
C00001151
|
| 55630 | SLC39A4, AEZ, AWMS2, ZIP4 | solute carrier family 39 (zinc transporter), member 4 |
C00001151
|
| 80834 | TAS1R2, GPR71, T1R2, TR2 | taste receptor, type 1, member 2 |
C00001151
|
| 83756 | TAS1R3, T1R3 | taste receptor, type 1, member 3 |
C00001151
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (12)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #278300 | Xanthinuria, type i |
P47989
|
KEGG DISEASE (16)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
Diseases related to CTD interactions
10 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D019969 | Amphetamine-Related Disorders |
C00001151
|
| D018149 | Glucose Intolerance |
C00001151
|
| D006461 | Hemolysis |
C00001151
|
| D006946 | Hyperinsulinism |
C00001151
|
| D006948 | Hyperkinesis |
C00001151
|
| D006973 | Hypertension |
C00001151
|
| D007333 | Insulin Resistance |
C00001151
|
| D009401 | Nephrosis |
C00001151
|
| C541083 | Non-alcoholic Fatty Liver Disease |
C00001151
|
| D019966 | Substance-Related Disorders |
C00001151
|