Helianthus annuus

• Index
• Plant Species
• Metabolite list (46)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Helianthus annuus
Genus	Helianthus
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Helianthus annuus
Linked NCBI taxonomy ID	4232
Linked level	species

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (46)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00006651	Cyanidin 3-xyloside					No. 2	No. 15
C00002374	Chrysanthemin / Cyanidin 3-O-glucoside	CHEMBL257839 CHEMBL1197952	C114438	1 / 0 / 1		No. 2	No. 15
C00001104	Tambulin	CHEMBL478811				No. 3	No. 15
C00039358	Helianthoside 1	CHEMBL427433				No. 4	No. 51
C00039363	Helianthoside B	CHEMBL227304				No. 4	No. 51
C00003530	Helianthoside A					No. 4	No. 51
C00039359	Helianthoside 2	CHEMBL388346				No. 4	No. 51
C00039362	Helianthoside 5	CHEMBL227303				No. 4	No. 51
C00039361	Helianthoside 4	CHEMBL437173				No. 4	No. 51
C00039360	Helianthoside 3	CHEMBL227302				No. 4	No. 51
C00000068	GA68 / Gibberellin A68					No. 40	No. 41
C00000072	GA72 / Gibberellin A72					No. 40	No. 41
C00000075	GA75 / Gibberellin A75					No. 40	No. 41
C00000076	GA76 / Gibberellin A76					No. 40	No. 41
C00000067	GA67 / Gibberellin A67					No. 40	No. 41
C00000064	GA64 / Gibberellin A64					No. 40	No. 41
C00000045	GA45 / Gibberellin A45					No. 40	No. 41
C00000044	GA44 / Gibberellin A44					No. 40	No. 41
C00000020	GA20 / Gibberellin A20					No. 40	No. 41
C00000004	GA4 / Gibberellin A4					No. 40	No. 41
C00000001	GA1 / Gibberellin A1		C422660			No. 40	No. 41
C00000574	GA101 / Gibberellin A101					No. 40	No. 41
C00000176	Brassinolide	CHEMBL563853 CHEMBL1801925 CHEMBL1967970	C023623		16 / 2	No. 68	No. 11
C00000181	Castasterone		C083545			No. 68	No. 11
C00000189	Brassinone / Norcastasterone / 28-Norcastasterone					No. 68	No. 11
C00014421	Heliannone A / 2',4-Dihydroxy-3',4'-dimethoxychalcone					No. 79
C00003338	Niveusin C					No. 94	No. 38
C00003785	Rubixanthin					No. 131	No. 59
C00000066	GA66 / Gibberellin A66					No. 187	No. 41
C00000065	GA65 / Gibberellin A65					No. 187	No. 41
C00000019	GA19 / Gibberellin A19		C120175			No. 187	No. 41
C00000324	GA100 / Gibberellin A100					No. 187	No. 41
C00007865	GA102 / Gibberellin A102					No. 187	No. 41
C00022912	Deepoxyneoxanthin / (3R,3'R)-6,7-Didehydro-5,6-dihydro-3,3',5-trihydroxy-beta,beta-carotene					No. 664	No. 59
C00000218	Jasmonic acid / trans-Jasmonic acid / 3-Oxo-2-(2Z-pentenyl)cyclotentylacetic acid	CHEMBL445499 CHEMBL449572	C011006	4 / 1 / 0		No. 707	No. 70
C00000109	Indole-3-acetaldehyde		C001655			No. 710	No. 4
C00000114	Tryptophol / Indole-3-ethanol	CHEMBL226545	C005949	2 / 4 / 2		No. 710	No. 4
C00049723	Heliannuol K / (+)-Heliannuol K					No. 1453
C00037248	Helianyl octanoate					No. 2571
C00000578	Ayapin	CHEMBL595798				No. 2617
C00000091	trans-Zeatin	CHEMBL525239	D015026	2 / 3 / 2	0 / 1	No. 2879
C00014651	5-Hydroxy-4,6,4'-trimethoxyaurone					No. 3237
C00001183	Fumaric acid	CHEMBL503160 CHEMBL539648	C032005	17 / 14 / 46	0 / 1	No. 3766
C00001151	Sucrose / (+)-Sucrose	CHEMBL253582 CHEMBL1976550	D013395	1 / 0 / 0	4 / 10	No. 3949
C00007452	Sucrose 6-phosphate		C535046			No. 3949
C00000318	Caprolactam	CHEMBL276218	D002209			No. 5191

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P16473	Thyrotropin receptor	Glycohormone receptor	C00000091 C00001183	3 / 2
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00000114	4 / 2
Q16798	NADP-dependent malic enzyme, mitochondrial	Enzyme	C00001183	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00001183	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00001183	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00002374	0 / 1
P04637	Cellular tumor antigen p53	Transcription Factor	C00001183	7 / 37
P00918	Carbonic anhydrase 2	Lyase	C00001183	1 / 2
P02768	Serum albumin	Secreted protein	C00001151	0 / 0
Q9GZT9	Egl nine homolog 1	Enzyme	C00001183	1 / 1
P42330	Aldo-keto reductase family 1 member C3	Enzyme	C00000218	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00001183	0 / 0
O75496	Geminin	Unclassified protein	C00001183	0 / 0
P17516	Aldo-keto reductase family 1 member C4	Enzyme	C00000218	1 / 0
P00915	Carbonic anhydrase 1	Lyase	C00001183	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000114	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00001183	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00001183	0 / 0
Q04828	Aldo-keto reductase family 1 member C1	Enzyme	C00000218	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001183	0 / 0
P52895	Aldo-keto reductase family 1 member C2	Enzyme	C00000218	1 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001183	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001183	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001183	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000091	0 / 0
Q9C0B1	Alpha-ketoglutarate-dependent dioxygenase FTO	Unclassified protein	C00001183	1 / 2

20 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000176
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00000176
637	BID, FP497	BH3 interacting domain death agonist	C00000176
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000176
891	CCNB1, CCNB	cyclin B1	C00000176
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00000176
898	CCNE1, CCNE	cyclin E1	C00000176
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00000176
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00000176
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00000176
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00000176
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000176
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000176
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00000176
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000176
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000176
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00001151
55630	SLC39A4, AEZ, AWMS2, ZIP4	solute carrier family 39 (zinc transporter), member 4	C00001151
80834	TAS1R2, GPR71, T1R2, TR2	taste receptor, type 1, member 2	C00001151
83756	TAS1R3, T1R3	taste receptor, type 1, member 3	C00001151

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions