KCF-S cluster No. 94 (50 metabolites)

Corresponding Phytochemical cluster No. 38

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (50)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	67

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Cumulative family count

class name	count
Asteraceae	67
Mustelidae	2

KEGG BRITE br08003

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Categories (2)

br08003 Category	# of metabolite
Germacrenes	8
Others	1

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metabolites link (10)

br08003 Category	KEGG ID	KNApSAcK ID
Germacrenes	C09474	C00000235
Germacrenes	C09402	C00000311
Germacrenes	C09403	C00000312
Germacrenes	C09401	C00003253
Germacrenes	C09412	C00003260
Germacrenes	C09413	C00003261
Germacrenes	C09433	C00003271
Germacrenes	C09517	C00003338
Others	C09607	C00003398
Germacrenes	C09474	C00011867

Metabolite list (50)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00000167	Eupalinin B
C00000168	1beta,10alpha-Epoxy-8beta,14-dihydroxy-4E,11(13)-germacradien-12,6-olide
C00000169	1beta,10alpha-Epoxy-8beta-hydroxy-14-acetoxy-4E,11(13)-germacradien-12,6-olide
C00000235	Heliangine	CHEMBL483867 CHEMBL517148 CHEMBL463123
C00000311	Elephantin	CHEMBL399907 CHEMBL1973224	C007584
C00000312	Elephantopin	CHEMBL400927 CHEMBL1990401	C045728
C00003253	Eleganin
C00003260	Acetylerioflorin / Erioflorin acetate	CHEMBL1984751	C063272
C00003261	Erioflorin methacrylate		C063271
C00003271	Eupahyssopin		C017306
C00003338	Niveusin C
C00003398	Zexbrevin B		C010647
C00011746	Orthopappolide methacrylate
C00011747	Nudaphantin	CHEMBL519353	C045727
C00011748	Tomenphantopin B
C00011750	Liscundin
C00011751	Liscunditrin	CHEMBL1719155 CHEMBL1984292		10 / 12 / 10
C00011862	Eupalinin C	CHEMBL258867 CHEMBL490650		1 / 4 / 1
C00011863	Eupalinin D
C00011864	Eupalinin A	CHEMBL258867 CHEMBL490650		1 / 4 / 1
C00011865	Erioflorin	CHEMBL1968292
C00011867	Leptocarpin / (Z,Z)-Heliangin	CHEMBL483867 CHEMBL517148 CHEMBL463123	C093534
C00011871	Cordifolia 54
C00011872	Cordifolia 55
C00011873	Sphaerocephalin
C00011874	Deltoidin B
C00011879	Fluctuadin
C00011880	Fluctuanin / Longipilin acetate
C00011881	Longipilin
C00012097	Isoelephantopin	CHEMBL400927 CHEMBL1990401
C00012098	Dihydroelephantopin
C00012101	Stizolicin	CHEMBL270307	C042748
C00012103	Deltoidin A
C00012104	Eupassopilin
C00012105	Liatripunctin	CHEMBL270307
C00012110	Punctatin / Punctaliatrin
C00012134	Niveusin A	CHEMBL205485 CHEMBL1968919		1 / 0 / 0
C00012138	Rotundin
C00012139	Vernopectolide A
C00012142	7-(Acetyloxy)-2,3,3a,4,5,6,7,8,9,11a-decahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester 2-methyl-2-propenoic acid
C00012147	Niveusin B	CHEMBL379917		1 / 0 / 0
C00012343	Balsamin
C00012360	Tanacin / Cyathin B5
C00022605	Tomenphantopin A
C00023189	3-Deacetyleupalinin A
C00042052	15-Acetoxyheliangin	CHEMBL464162
C00042125	3-epi-Heliangin / (-)-3-epi-Heliangin	CHEMBL483867 CHEMBL517148 CHEMBL463123
C00042506	Eupakirunsin D / (-)-Eupakirunsin D	CHEMBL465405
C00049404	Tomenphantin A	CHEMBL453794
C00049405	Tomenphantin B	CHEMBL509174

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q04206	Transcription factor p65	Transcription Factor	C00012134 C00012147	0 / 0
P31749	RAC-alpha serine/threonine-protein kinase	Akt	C00011862 C00011864	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00011751	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00011751	2 / 0
O75496	Geminin	Unclassified protein	C00011751	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00011751	4 / 2
P11473	Vitamin D3 receptor	NR1I1	C00011751	2 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00011751	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00011751	2 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00011751	0 / 0
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00011751	0 / 3
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00011751	2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions