KCF-S cluster No. 2414 (5 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (5)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Liliopsida	2
rosids	1
asterids	1

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Cumulative family count

class name	count
Methanococcaceae	4
Poaceae	2
Pseudomonadaceae	1
Sapotaceae	1
Brassicaceae	1
Sphingomonadaceae	1
Enterobacteriaceae	1
Thermotogaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (5)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00000769	alpha-Oxoglutaric acid / alpha-Ketoglutaric acid	CHEMBL1686	C029743	13 / 6 / 7	8 / 0
C00000770	2-Oxoadipic acid / alpha-Ketoadipate / alpha-Ketoadipic acid		C001918
C00000771	alpha-Oxopimelic acid / alpha-Ketopimelic acid	CHEMBL185075		1 / 1 / 0
C00000773	alpha-Ketosuberate / 2-Oxooctanedioic acid / alpha-Ketosuberic acid		C062868
C00001197	Oxalacetic acid	CHEMBL2075016	D062907		1 / 0

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9H6Z9	Egl nine homolog 3	Enzyme	C00000769	0 / 0
Q9Y694	Solute carrier family 22 member 7	Unclassified protein	C00000769	0 / 0
P08183	Multidrug resistance protein 1	drug	C00000769	1 / 0
Q9GZT9	Egl nine homolog 1	Enzyme	C00000769	1 / 1
P13674	Prolyl 4-hydroxylase subunit alpha-1	Enzyme	C00000769	0 / 0
Q96KS0	Egl nine homolog 2	Enzyme	C00000769	0 / 0
Q9NWT6	Hypoxia-inducible factor 1-alpha inhibitor	Enzyme	C00000769	0 / 0
Q8TCC7	Solute carrier family 22 member 8	Antiporter	C00000769	0 / 0
Q4U2R8	Solute carrier family 22 member 6	Antiporter	C00000769	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000769	0 / 0
Q86XE5	Probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial	Enzyme	C00000771	1 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000769	0 / 0
P10275	Androgen receptor	NR3C4	C00000769	3 / 4
O76082	Solute carrier family 22 member 5	Unclassified protein	C00000769	1 / 2

9 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
8424	BBOX1, BBH, BBOX, G-BBH, gamma-BBH	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (EC:1.14.11.1)	C00000769
728294	D2HGDH, D2HGD	D-2-hydroxyglutarate dehydrogenase (EC:1.1.99.-)	C00000769
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00000769
8290	HIST3H3, H3.4, H3/g, H3FT, H3t	histone cluster 3, H3	C00000769
55818	KDM3A, JHDM2A, JHMD2A, JMJD1, JMJD1A, TSGA	lysine (K)-specific demethylase 3A	C00000769
54681	P4HTM, EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	C00000769
9356	SLC22A6, HOAT1, OAT1, PAHT, ROAT1	solute carrier family 22 (organic anion transporter), member 6	C00000769
7428	VHL, HRCA1, RCA1, VHL1, pVHL	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	C00000769
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00001197

Related Diseases

Diseases related to proteins in ChEMBL interactions