Saxifraga stolonifera Meerb.

• Index
• Plant Species
• Metabolite list (19)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Saxifraga stolonifera Meerb.
Genus	Saxifraga
Family	Saxifragaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Saxifraga
Linked NCBI taxonomy ID	3798
Linked level	genus

Family

Family in NCBI taxonomy	Saxifragaceae
ID	3792

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (19)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001232	Oleic acid / (Z)-9-Octadecenoic acid	CHEMBL8659 CHEMBL460657	D019301	30 / 19 / 20	26 / 9	No. 184	No. 68
C00001238	Stearic acid	CHEMBL46403	C031183	15 / 17 / 19	6 / 1	No. 184	No. 68
C00001233	Palmitic acid	CHEMBL82293	D019308	16 / 8 / 8	35 / 1	No. 184	No. 68
C00001224	Linoleic acid / (Z,Z)-9,12-Octadecadienoic acid	CHEMBL267476		29 / 31 / 28		No. 367	No. 68
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00029811	Benzyl alcohol / (Hydroxymethyl)benzene	CHEMBL720	D019905	94 / 41 / 36	1 / 6	No. 885
C00003047	Linalool / (R)-linalool / (R)-(-)-3,7-Dimethyl-1,6-octadien-3-ol	CHEMBL25306 CHEMBL235672	C018584	6 / 8 / 2	35 / 4	No. 958	No. 34
C00029674	alpha-Terpineol	CHEMBL447597 CHEMBL449810	C016775	3 / 16 / 11		No. 983	No. 35
C00001231	Caprylic acid / Octanoic acid / n-Octanoic acid	CHEMBL324846	C031492	10 / 14 / 13	2 / 1	No. 1141	No. 68
C00001228	Myristic acid / Tetradecanoic acid / n-Tetradecanoic acid	CHEMBL111077	D019814	17 / 9 / 10	3 / 0	No. 1141	No. 68
C00001213	Capric acid / Decanoic acid / n-Decanoic acid	CHEMBL107498	C031071	8 / 11 / 6	4 / 0	No. 1141	No. 68
C00002645	p-Cresol / 4-Methylphenol	CHEMBL16645	C032538	8 / 4 / 4	10 / 4	No. 1546
C00000845	Geraniol	CHEMBL25719 CHEMBL452683		96 / 41 / 41		No. 1575	No. 34
C00000844	Citronellol	CHEMBL395827 CHEMBL1907993 CHEMBL1907995	C007078	7 / 5 / 4	1 / 1	No. 1948	No. 34
C00003046	Geranyl acetate / trans-Geranyl acetate / Acetic acid geraniol ester	CHEMBL1369384		5 / 3 / 4		No. 2157	No. 34
C00003040	p-Cymene	CHEMBL442915	C007210			No. 2172	No. 35
C00000861	Terpinolene	CHEMBL454697	C027009		1 / 0	No. 3725
C00033253	Norbergenin	CHEMBL463164	C063922			No. 4068
C00001189	Isovaleric acid / 3-Methylbutanoic acid	CHEMBL568737	C008216		4 / 0	No. 5262

Human Protein / Gene in interactions

155 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000844 C00000845 C00001224 C00001238 C00003046 C00003047	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00000845 C00001224 C00001228 C00001232 C00001233 C00003046	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000845 C00001213 C00001231 C00001233 C00001238 C00029811	0 / 1
O75496	Geminin	Unclassified protein	C00001213 C00001224 C00001228 C00001231 C00001232 C00001233	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000805 C00001213 C00001224 C00001231 C00001238 C00029811	3 / 2
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00001224 C00001228 C00001232 C00001233 C00001238	2 / 2
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000844 C00002645 C00003046 C00029811	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000845 C00001232 C00001238 C00029811	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805 C00001213 C00001232 C00002645	0 / 0
P10275	Androgen receptor	NR3C4	C00001224 C00001233 C00002645 C00003046	3 / 4
P00352	Retinal dehydrogenase 1	Enzyme	C00000844 C00001224 C00001231 C00003046	0 / 0
P15090	Fatty acid-binding protein, adipocyte	Other cytosolic protein	C00001224 C00001232 C00001233 C00001238	0 / 0
P03372	Estrogen receptor	NR3A1	C00000845 C00001224 C00001233 C00029811	1 / 1
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00001224 C00001228 C00001232 C00001233	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000845 C00001228 C00001238 C00029811	2 / 3
P05413	Fatty acid-binding protein, heart	Other cytosolic protein	C00001224 C00001232 C00001233	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00001213 C00001224 C00001232	5 / 3
P28482	Mitogen-activated protein kinase 1	Erk	C00000805 C00000845 C00029811	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001224 C00001232 C00001233	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000845 C00001232 C00029811	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001224 C00001228 C00001238	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00001224 C00001231 C00029674	11 / 10
Q9UBT6	DNA polymerase kappa	Enzyme	C00001224 C00001232 C00001238	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001224 C00001232 C00001238	3 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00001228 C00001232 C00003047	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000845 C00001224 C00029811	0 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000845 C00001232 C00001238	1 / 2
Q9UGP5	DNA polymerase lambda	Enzyme	C00001224 C00001232 C00001238	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000844 C00003047 C00029674	5 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000845 C00001232 C00029811	2 / 2
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000844 C00000845 C00029811	0 / 3
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000844 C00002645 C00029811	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00001213 C00001228 C00001231	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00001213 C00001228 C00001231	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001224 C00001228 C00001232	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00000844 C00000845 C00003047	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000845 C00002645 C00029811	1 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000845 C00001224 C00029811	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00001213 C00003047 C00029674	3 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000845 C00029811	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000845 C00029811	0 / 1
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000845 C00029811	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000845 C00029811	1 / 8
P11387	DNA topoisomerase 1	Isomerase	C00001232 C00001233	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000845 C00029811	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00000845 C00029811	2 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000845 C00029811	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000845 C00029811	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000845 C00029811	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000845 C00029811	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000845 C00029811	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000845 C00029811	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000845 C00029811	1 / 1
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000845 C00029811	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000845 C00029811	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000845 C00029811	1 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000845 C00029811	0 / 1
P30542	Adenosine receptor A1	Adenosine receptor	C00000845 C00029811	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000845 C00029811	0 / 0
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000845 C00029811	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000845 C00029811	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000845 C00029811	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000845 C00029811	1 / 1
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000845 C00029811	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000845 C00029811	1 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000845 C00029811	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000845 C00029811	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000845 C00029811	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000845 C00029811	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000845 C00029811	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000845 C00029811	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000845 C00029811	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000845 C00029811	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000845 C00029811	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000845 C00029811	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00000845 C00029811	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000845 C00029811	1 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00002645 C00029811	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000845 C00029811	0 / 0
P08311	Cathepsin G	S1A	C00000845 C00029811	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000845 C00029811	1 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000845 C00029811	1 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000845 C00029811	0 / 0
P03956	Interstitial collagenase	M10A	C00000845 C00029811	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000845 C00029811	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000845 C00029811	0 / 1
P00918	Carbonic anhydrase 2	Lyase	C00000845 C00029811	1 / 2
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000845 C00029811	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00001238 C00003047	3 / 1
P14780	Matrix metalloproteinase-9	M10A	C00000845 C00029811	2 / 2
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000845 C00001224	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000845 C00029811	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000845 C00029811	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00000845 C00029811	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000845 C00029811	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000845 C00029811	2 / 0
P29466	Caspase-1	C14	C00000845 C00029811	0 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000845 C00029811	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000845 C00029811	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000845 C00029811	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000845 C00029811	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000845 C00029811	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000845 C00029811	0 / 0
P13726	Tissue factor	Membrane receptor	C00001224 C00001232	0 / 0
O00255	Menin	Unclassified protein	C00000845 C00001238	2 / 5
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000845 C00029811	1 / 1
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000845 C00029811	1 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000845 C00029811	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000845 C00029811	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000845 C00029811	0 / 0
Q01469	Fatty acid-binding protein, epidermal	Other cytosolic protein	C00001232 C00001233	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000845 C00029811	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000845 C00029811	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000845 C00029811	0 / 0
P08246	Neutrophil elastase	S1A	C00000845 C00029811	2 / 1
P25105	Platelet-activating factor receptor	PAF receptor	C00000845 C00029811	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000845 C00029811	0 / 0
O60603	Toll-like receptor 2	Membrane receptor	C00001228 C00001233	1 / 1
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000845 C00029811	0 / 0
P35610	Sterol O-acyltransferase 1	Enzyme	C00001224 C00001232	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000845 C00029811	1 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000845 C00029811	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000845 C00029811	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000845 C00029811	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000845 C00029811	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000845 C00029811	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000845 C00029811	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001232	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00001224	2 / 2
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00001238	0 / 0
P07148	Fatty acid-binding protein, liver	Unclassified protein	C00001232	0 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00001224	0 / 0
Q4U2R8	Solute carrier family 22 member 6	Antiporter	C00001231	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00001228	0 / 0
O14842	Free fatty acid receptor 1	Free fatty acid receptor	C00001224	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001232	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001232	0 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00001232	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001232	4 / 3
P12104	Fatty acid-binding protein, intestinal	Other cytosolic protein	C00001233	0 / 0
P10145	Interleukin-8	Secreted protein	C00002645	0 / 0
P50225	Sulfotransferase 1A1	Enzyme	C00002645	0 / 0
Q8TCC7	Solute carrier family 22 member 8	Antiporter	C00001231	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00001228	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00001228	2 / 2
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001228	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00001232	1 / 2
P08183	Multidrug resistance protein 1	drug	C00001233	1 / 0
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00001224	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00001224	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00001233	0 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00001232	1 / 4
Q05193	Dynamin-1	Structural	C00001228	0 / 0
Q9NSA0	Solute carrier family 22 member 11	Transporter	C00001231	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001228	1 / 1

103 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00001228 C00001231 C00001232 C00001233 C00001238
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00001213 C00001228 C00001233 C00001238
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00001232 C00001233 C00001238 C00003047
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001232 C00001233 C00002645
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00001232 C00001233 C00002645
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00001232 C00001233 C00001238
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001232 C00001233 C00001238
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000861 C00001233 C00003047
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00001233 C00001238
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00001232 C00001233
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00001232 C00001233
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00001213 C00001231
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00001189 C00001213
6720	SREBF1, SREBP-1c, SREBP1, bHLHd1	sterol regulatory element binding transcription factor 1	C00001232
1447	CSN2, CASB	casein beta	C00003047
1509	CTSD, CLN10, CPSD	cathepsin D (EC:3.4.23.5)	C00003047
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00003047
1028	CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	C00003047
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003047
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00003047
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00003047
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00003047
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00003047
3297	HSF1, HSTF1	heat shock transcription factor 1	C00003047
3320	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	C00003047
3308	HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY	heat shock 70kDa protein 4	C00003047
3316	HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP	heat shock 27kDa protein 2	C00003047
3398	ID2, GIG8, ID2A, ID2H, bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	C00003047
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00003047
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00003047
8850	KAT2B, CAF, P, P/CAF, PCAF	K(lysine) acetyltransferase 2B (EC:2.3.1.48)	C00003047
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00003047
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00003047
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00003047
4852	NPY, PYY4	neuropeptide Y	C00003047
100124292			C00003047
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00003047
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00003047
7471	WNT1, BMND16, INT1, OI15	wingless-type MMTV integration site family, member 1	C00003047
26118	WSB1, SWIP1, WSB-1	WD repeat and SOCS box containing 1	C00003047
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00003047
9076	CLDN1, CLD1, ILVASC, SEMP1	claudin 1	C00001213
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00003047
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00003047
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00003047
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00003047
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00003047
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00001189
6376	CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin	chemokine (C-X3-C motif) ligand 1	C00002645
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002645
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00002645
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00002645
50848	F11R, CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1	F11 receptor	C00002645
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002645
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00002645
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00001189
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00002645
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00001232
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00001232
335	APOA1	apolipoprotein A-I	C00001232
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00001232
847	CAT	catalase (EC:1.11.1.6)	C00001232
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00001232
1869	E2F1, E2F-1, RBAP1, RBBP3, RBP3	E2F transcription factor 1	C00001232
7442	TRPV1, VR1	transient receptor potential cation channel, subfamily V, member 1	C00000844
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00001232
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001232
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00001232
778733			C00001232
100136658			C00001232
5467	PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB	peroxisome proliferator-activated receptor delta	C00001232
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00001232
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00001232
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00001232
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00001189
6514	SLC2A2, GLUT2	solute carrier family 2 (facilitated glucose transporter), member 2	C00001232
1030	CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	C00003047
581	BAX, BCL2L4	BCL2-associated X protein	C00001233
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00001233
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00001233
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00001233
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00001233
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00001233
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00001233
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00001233
3481	IGF2, C11orf43, IGF-II, PP9974	insulin-like growth factor 2 (somatomedin A)	C00001233
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00001233
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00001233
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00001233
4493	MT1E, MT1, MTD	metallothionein 1E	C00001233
4494	MT1F, MT1	metallothionein 1F	C00001233
4496	MT1H, MT-0, MT-1H, MT-IH, MT1	metallothionein 1H	C00001233
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00001233
4502	MT2A, MT2	metallothionein 2A	C00001233
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00001233
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00001233
29893	PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP	PSMC3 interacting protein	C00001233
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001233
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00001233
23216	TBC1D1, TBC, TBC1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	C00001233
7351	UCP2, BMIQ4, SLC25A8, UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	C00001233
199974	CYP4Z1, CYP4A20	cytochrome P450, family 4, subfamily Z, polypeptide 1 (EC:1.14.14.1)	C00001228
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00029811

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