Species

KNApSAcK Entry

Organism name Cuphea spp.
Genus Cuphea
Family Lythraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cuphea
Linked NCBI taxonomy ID 3929
Linked level genus

Family

Family in NCBI taxonomy Lythraceae
ID 3928

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001213 External link 512 Capric acid
/ Decanoic acid
/ n-Decanoic acid
CHEMBL107498
C031071
8 / 11 / 6 4 / 0 No. 1141 No. 68

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00001213 3 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00001213 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00001213 3 / 2
O75496 Geminin Unclassified protein C00001213 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00001213 0 / 1
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00001213 5 / 3
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00001213 0 / 0
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00001213 0 / 0

4 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
128 ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284) C00001213
9076 CLDN1, CLD1, ILVASC, SEMP1 claudin 1 C00001213
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00001213
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00001213

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#218800 Crigler-najjar syndrome, type i P22310
#606785 Crigler-najjar syndrome, type ii P22310
#143500 Gilbert syndrome P22310
#137800 Glioma susceptibility 1; glm1 P37231
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231

KEGG DISEASE (6)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)