| Organism name | Cuphea spp. | 
|---|---|
| Genus | Cuphea | 
| Family | Lythraceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Cuphea | 
|---|---|
| Linked NCBI taxonomy ID | 3929 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Lythraceae | 
|---|---|
| ID | 3928 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | 
                        # of proteins in
                         ChEMBL interaction / related OMIM / related KEGG DISEASE  | 
                      
                        # of genes in
                         CTD interaction / related diseases  | 
                      
                        KCF-S
                         cluster  | 
                      
                        phytochemical
                         cluster  | 
                      figure | 
|---|---|---|---|---|---|---|---|---|
| 
                        C00001213
                        
                           | 
                      
                        Capric acid
                         / Decanoic acid / n-Decanoic acid  | 
                      
                        CHEMBL107498
                         | 
                      
                        C031071
                         | 
                      8 / 11 / 6 | 4 / 0 | No. 1141 | No. 68 | 
                         
                       | 
                    
| accession | description | class description | KNApSAcK metabolite in interactions | 
                          # of diseases
                           (OMIM / KEGG)  | 
                      
|---|---|---|---|---|
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00001213 | 3 / 0 | 
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00001213 | 0 / 0 | 
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001213 | 3 / 2 | 
| O75496 | Geminin | Unclassified protein | C00001213 | 0 / 0 | 
| P04150 | Glucocorticoid receptor | NR3C1 | C00001213 | 0 / 1 | 
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00001213 | 5 / 3 | 
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00001213 | 0 / 0 | 
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00001213 | 0 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 128 | ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR | alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284) | 
                          C00001213
                           | 
                      
| 9076 | CLDN1, CLD1, ILVASC, SEMP1 | claudin 1 | 
                          C00001213
                           | 
                      
| 10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 
                          C00001213
                           | 
                      
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) | 
                          C00001213
                           | 
                      
| OMIM | preferred title | UniProt | 
|---|---|---|
| %606641 | Body mass index; bmi | 
                            P37231
                             | 
                        
| #609338 | Carotid intimal medial thickness 1 | 
                            P37231
                             | 
                        
| #218800 | Crigler-najjar syndrome, type i | 
                            P22310
                             | 
                        
| #606785 | Crigler-najjar syndrome, type ii | 
                            P22310
                             | 
                        
| #143500 | Gilbert syndrome | 
                            P22310
                             | 
                        
| #137800 | Glioma susceptibility 1; glm1 | 
                            P37231
                             | 
                        
| #603373 | Hyperthyroidism, familial gestational | 
                            P16473
                             | 
                        
| #609152 | Hyperthyroidism, nonautoimmune | 
                            P16473
                             | 
                        
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 | 
                            P16473
                             | 
                        
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 | 
                            P37231
                             | 
                        
| #601665 | Obesity | 
                            P37231
                             | 
                        
| KEGG | name | UniProt | 
|---|---|---|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | 
                            P04150
                            (related)
                             | 
                        
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | 
                            P16473
                            (related)
                             | 
                        
| H01269 | Congenital hyperthyroidism | 
                            P16473
                            (related)
                             | 
                        
| H00032 | Thyroid cancer | 
                            P37231
                            (related)
                             | 
                        
| H00409 | Type II diabetes mellitus | 
                            P37231
                            (related)
                             | 
                        
| H00420 | Familial partial lipodystrophy (FPL) | 
                            P37231
                            (related)
                             |