Rhodiola rosea L.

• Index
• Plant Species
• Metabolite list (70)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Rhodiola rosea L.
Genus	Rhodiola
Family	Crassulaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Rhodiola rosea
Linked NCBI taxonomy ID	203015
Linked level	species

Family

Family in NCBI taxonomy	Crassulaceae
ID	3781

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (70)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00031186	Rosin / Rosin X / (-)-Rosin / trans-Cinnamyl beta-D-glucopyranoside					No. 45	No. 72
C00031274	Salidroside / Rhodioloside / (-)-Rhodioloside / Tyrosol alpha-(beta-D-glucopyranoside)	CHEMBL465208 CHEMBL1899113	C009172	3 / 0 / 0		No. 45	No. 72
C00002707	Picein / 4-Hydroxyacetophenone 4-glucoside	CHEMBL1512620	C050880	3 / 0 / 0		No. 45	No. 72
C00031184	Rosarin					No. 128	No. 72
C00031185	Rosavin	CHEMBL1083511		1 / 1 / 1		No. 128	No. 72
C00030479	Hexadecanoic acid / n-Hexadecanoic acid	CHEMBL82293	D019308	16 / 8 / 8	35 / 1	No. 184	No. 68
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00037531	Myrtenol	CHEMBL443408				No. 476	No. 35
C00000829	trans-Pinocarveol					No. 476	No. 35
C00000816	beta-Pinene	CHEMBL501351	C010789			No. 476	No. 35
C00003110	Caryophyllene / (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene	CHEMBL445740 CHEMBL448700		2 / 3 / 7		No. 478	No. 38
C00034818	cis-Linalool oxide	CHEMBL29660 CHEMBL282731 CHEMBL63592 CHEMBL397730		14 / 17 / 50		No. 518	No. 6
C00037576	Octadecyl acetate					No. 793
C00000823	Limonene	CHEMBL15799 CHEMBL449062	C008281	7 / 21 / 48	6 / 6	No. 848	No. 35
C00003050	Perilla aldehyde / (R)-(+)-Perillaldehyde	CHEMBL442913 CHEMBL469537	C033342	2 / 1 / 0	9 / 0	No. 848	No. 35
C00030100	Decanol / 1-Decanol / n-Decanol	CHEMBL25363	C029383	1 / 0 / 0	1 / 0	No. 877
C00030152	Dodecanol / 1-Dodecanol	CHEMBL24722	D007851			No. 877
C00035115	Benzenepropanol / 3-Phenylpropanol / Hydrocinnamic alcohol	CHEMBL1606391	C016655	3 / 1 / 4		No. 885
C00002663	2-Phenylethanol / Phenethyl alcohol / Phenylethyl alcohol / beta-Phenethyl alcohol	CHEMBL448500	D010626	2 / 1 / 1		No. 885
C00003047	Linalool / (R)-linalool / (R)-(-)-3,7-Dimethyl-1,6-octadien-3-ol	CHEMBL25306 CHEMBL235672	C018584	6 / 8 / 2	35 / 4	No. 958	No. 34
C00000156	Carvacrol	CHEMBL281202	C073316	10 / 6 / 1	4 / 2	No. 969	No. 35
C00000155	Thymol	CHEMBL29411	D013943	9 / 17 / 14	12 / 0	No. 969	No. 35
C00029674	alpha-Terpineol	CHEMBL447597 CHEMBL449810	C016775	3 / 16 / 11		No. 983	No. 35
C00001228	Myristic acid / Tetradecanoic acid / n-Tetradecanoic acid	CHEMBL111077	D019814	17 / 9 / 10	3 / 0	No. 1141	No. 68
C00001231	Caprylic acid / Octanoic acid / n-Octanoic acid	CHEMBL324846	C031492	10 / 14 / 13	2 / 1	No. 1141	No. 68
C00001213	Capric acid / Decanoic acid / n-Decanoic acid	CHEMBL107498	C031071	8 / 11 / 6	4 / 0	No. 1141	No. 68
C00001221	Lauric acid / Docosanoic acid / n-Dodecanoic acid	CHEMBL108766	C030358	19 / 25 / 14	11 / 0	No. 1141	No. 68
C00000836	cis-Thujone / (+)-Thujone / beta-Thujone	CHEMBL1444078		2 / 3 / 2		No. 1161	No. 35
C00037338	Isopinocamphone					No. 1161	No. 35
C00011067	Tricyclene / Teresantanane					No. 1225
C00035341	Menthone	CHEMBL276311 CHEMBL1719455	C019466	1 / 0 / 0	3 / 0	No. 1288	No. 35
C00037333	Isomenthone	CHEMBL276311 CHEMBL1719455		1 / 0 / 0		No. 1288	No. 35
C00031258	Sabinene / 4(10)-Thujene	CHEMBL452687	C035127			No. 1343	No. 35
C00000814	(-)-trans-Carveol	CHEMBL1385229 CHEMBL1907992 CHEMBL1908058		6 / 15 / 40		No. 1555	No. 35
C00037652	Pinocarvone					No. 1561	No. 35
C00003036	Neral / Citral Z	CHEMBL1080997		6 / 7 / 9		No. 1575	No. 34
C00000845	Geraniol	CHEMBL25719 CHEMBL452683		96 / 41 / 41		No. 1575	No. 34
C00000855	Nerol / cis-Geraniol	CHEMBL25719 CHEMBL452683		96 / 41 / 41		No. 1575	No. 34
C00000843	cis-beta-Ocimene					No. 1698	No. 34
C00035062	Carvone	CHEMBL15676 CHEMBL501949	C006923	8 / 9 / 9	5 / 2	No. 1740	No. 35
C00030830	Nonanol / n-Nonanol	CHEMBL24563	C014713		1 / 0	No. 1749
C00001264	Octanol / n-Octanol / 1-Octanol / Octan-1-ol	CHEMBL26215	D020003	5 / 6 / 5	2 / 0	No. 1749
C00010872	beta-Phellandrene / (+/-)-beta-Phellandrene	CHEMBL444254	C058582			No. 1898	No. 35
C00030828	Nonanal / n-Nonanal		C008664		1 / 1	No. 1993
C00030804	n-Decanal		C021170		2 / 0	No. 1993
C00029331	(E)-2-Nonenal / trans-2-Nonenal	CHEMBL450072		1 / 0 / 0		No. 2140
C00003040	p-Cymene	CHEMBL442915	C007210			No. 2172	No. 35
C00032864	Cumin alcohol / Cuminyl alcohol / p-Isopropylbenzyl alcohol					No. 2172	No. 35
C00000853	Myrcene	CHEMBL455491	C008574	3 / 3 / 3		No. 2285	No. 34
C00019221	Benzyl benzoate	CHEMBL1239	C006723	12 / 5 / 8	3 / 2	No. 2308
C00002725	Cinnamaldehyde	CHEMBL293492	C012843	98 / 49 / 42	151 / 23	No. 2320	No. 6
C00037855	Styrene	CHEMBL285235	D020058	5 / 6 / 4	27 / 9	No. 2320	No. 6
C00003029	Camphene	CHEMBL506889 CHEMBL510535	C019286			No. 2460	No. 35
C00003061	gamma-Terpinene / 1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene	CHEMBL449693	C018669			No. 2468	No. 35
C00003060	alpha-Terpinene					No. 2468	No. 35
C00036387	1,4-p-Menthadien-7-ol					No. 2468	No. 35
C00000839	3-Carene	CHEMBL506854	C030218			No. 2690	No. 35
C00036969	Cuminyl acetate					No. 3288	No. 35
C00035072	Cinnamyl acetate					No. 3509
C00000357	Hexanal	CHEMBL280331	C010463		7 / 0	No. 3593
C00000358	n-Hexanol	CHEMBL14085	C036260	3 / 6 / 3		No. 3722
C00035784	1-Pentanol / n-Pentanol	CHEMBL14568	C024999	2 / 7 / 5	2 / 0	No. 3722
C00000861	Terpinolene	CHEMBL454697	C027009		1 / 0	No. 3725
C00003039	Cuminaldehyde / Cuminyl aldehyde / 4-Isopropyl benzaldehyde	CHEMBL161577	C007165	2 / 4 / 2		No. 3751	No. 35
C00002740	Estragol / Esdragol / Estragole	CHEMBL470671	C007633	10 / 16 / 43	3 / 5	No. 3933	No. 6
C00029844	Bornyl acetate	CHEMBL1439452	C071528	4 / 1 / 4		No. 4140	No. 35
C00037789	Santene					No. 4737
C00034775	6-Methyl-5-hepten-2-one	CHEMBL46340	C029750			No. 5297
C00034989	(E)-Ocimene / trans-Ocimene					No. 6181
C00034452	Benzaldehyde	CHEMBL15972	C032175	8 / 7 / 3	3 / 1	No. 6311

Human Protein / Gene in interactions

164 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P16473	Thyrotropin receptor	Glycohormone receptor	C00000358 C00000805 C00000814 C00000836 C00000853 C00001213 C00001221 C00001231 C00002740 C00037855	3 / 2
P00352	Retinal dehydrogenase 1	Enzyme	C00001221 C00001231 C00001264 C00002725 C00002740 C00003036 C00034452 C00035062 C00037855	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000845 C00000853 C00000855 C00001213 C00001231 C00001264 C00002725 C00030479 C00037855	0 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00000836 C00001221 C00001228 C00001264 C00002707 C00002740 C00003047 C00019221 C00031274	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00000358 C00000823 C00001221 C00001264 C00003036 C00003047 C00035062 C00037855	3 / 1
O75496	Geminin	Unclassified protein	C00001213 C00001228 C00001231 C00002663 C00002707 C00002725 C00030479 C00031274	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00000845 C00000853 C00000855 C00001221 C00001228 C00019221 C00030100 C00030479	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000155 C00000156 C00000814 C00001213 C00001221 C00003047 C00029674	3 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002740 C00003036 C00019221 C00029844 C00034818 C00035115	0 / 1
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805 C00001213 C00001221 C00002725 C00034818 C00035062	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002740 C00003036 C00019221 C00029844 C00034818 C00035115	1 / 4
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000358 C00000823 C00002725 C00019221 C00035062 C00037855	0 / 0
P03372	Estrogen receptor	NR3A1	C00000845 C00000855 C00001221 C00002725 C00030479 C00034452	1 / 1
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00000155 C00000156 C00000845 C00000855 C00003047	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000155 C00000156 C00000814 C00003047 C00029674	5 / 1
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000156 C00001213 C00001221 C00001228 C00001231	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000845 C00000855 C00003110 C00019221 C00035062	1 / 2
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000155 C00000823 C00000845 C00000855 C00002725	0 / 3
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000156 C00001213 C00001221 C00001228 C00001231	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000156 C00000845 C00000855 C00002725 C00031274	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000155 C00000823 C00001231 C00002725 C00029674	11 / 10
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000845 C00000855 C00002740 C00003047 C00034818	0 / 0
O75762	Transient receptor potential cation channel subfamily A member 1	Unclassified protein	C00000155 C00000156 C00002725 C00003050	1 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000845 C00000855 C00002725 C00034818	0 / 1
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000823 C00000845 C00000855 C00034452	0 / 0
P10145	Interleukin-8	Secreted protein	C00001221 C00002725 C00034452 C00034818	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001228 C00029844 C00035341 C00037333	0 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00003036 C00003039 C00003050 C00029331	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000845 C00000855 C00002725 C00002740	0 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000845 C00000855 C00001221 C00002725	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000845 C00000855 C00002725 C00034452	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001228 C00002663 C00019221 C00034818	1 / 1
O00255	Menin	Unclassified protein	C00000845 C00000855 C00003110 C00035062	2 / 5
P04637	Cellular tumor antigen p53	Transcription Factor	C00000814 C00000823 C00002740 C00034818	7 / 37
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000845 C00000855 C00002725 C00019221	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00000805 C00000845 C00000855 C00002725	0 / 0
P10275	Androgen receptor	NR3C4	C00001221 C00003036 C00030479 C00035784	3 / 4
P03956	Interstitial collagenase	M10A	C00000845 C00000855 C00002725	0 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000845 C00000855 C00002725	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000845 C00000855 C00002725	1 / 1
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000845 C00000855 C00002725	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000845 C00000855 C00002725	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000845 C00000855 C00002725	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000845 C00000855 C00002725	0 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000845 C00000855 C00002725	1 / 8
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000845 C00000855 C00002725	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000845 C00000855 C00001228	2 / 3
P14416	D(2) dopamine receptor	Dopamine receptor	C00000845 C00000855 C00002725	2 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000845 C00000855 C00002725	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000845 C00000855 C00002725	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000845 C00000855 C00002725	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000845 C00000855 C00002725	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000845 C00000855 C00002725	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000845 C00000855 C00002725	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000845 C00000855 C00002725	1 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000845 C00000855 C00002725	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000845 C00000855 C00002725	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000845 C00000855 C00002725	1 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00000845 C00000855 C00002725	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000845 C00000855 C00002725	1 / 1
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000845 C00000855 C00002725	0 / 1
P00918	Carbonic anhydrase 2	Lyase	C00000845 C00000855 C00002725	1 / 2
P30542	Adenosine receptor A1	Adenosine receptor	C00000845 C00000855 C00002725	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000845 C00000855 C00002725	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000845 C00000855 C00002725	1 / 1
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000845 C00000855 C00002725	1 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000845 C00000855 C00002725	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000155 C00000156 C00000814	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000845 C00000855 C00002725	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000845 C00000855 C00002725	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000845 C00000855 C00002725	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000845 C00000855 C00002725	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000845 C00000855 C00002725	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000845 C00000855 C00002725	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000845 C00000855 C00002725	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000845 C00000855 C00002725	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000845 C00000855 C00002725	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000845 C00000855 C00002725	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000845 C00000855 C00002725	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000845 C00000855 C00002725	2 / 2
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000845 C00000855 C00002725	1 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000845 C00000855 C00002725	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00000845 C00000855 C00002725	0 / 0
P08311	Cathepsin G	S1A	C00000845 C00000855 C00002725	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000845 C00000855 C00002725	1 / 0
P17252	Protein kinase C alpha type	Alpha	C00000845 C00000855 C00002725	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000845 C00000855 C00002725	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000845 C00000855 C00002725	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000845 C00000855 C00002725	0 / 0
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000845 C00000855 C00002725	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000845 C00000855 C00002725	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000845 C00000855 C00002725	0 / 0
P29466	Caspase-1	C14	C00000845 C00000855 C00002725	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000845 C00000855 C00002725	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00001221 C00029844 C00035115	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000845 C00000855 C00002725	1 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000845 C00000855 C00002725	1 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000845 C00000855 C00002725	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000845 C00000855 C00002725	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000845 C00000855 C00002725	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000845 C00000855 C00002725	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000845 C00000855 C00002725	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000845 C00000855 C00002725	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000845 C00000855 C00002725	2 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000845 C00000855 C00002725	0 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000845 C00000855 C00002725	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000845 C00000855 C00002725	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000845 C00000855 C00002725	0 / 0
P08246	Neutrophil elastase	S1A	C00000845 C00000855 C00002725	2 / 1
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000845 C00000855 C00002725	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000845 C00000855 C00002725	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000845 C00000855 C00002725	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000845 C00000855 C00002725	2 / 2
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000845 C00000855 C00002725	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000845 C00000855 C00002725	1 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000845 C00000855 C00002725	1 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000845 C00000855 C00002725	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000845 C00000855 C00002725	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000845 C00000855 C00002725	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001264 C00034818	3 / 3
O60603	Toll-like receptor 2	Membrane receptor	C00001228 C00030479	1 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00002740 C00035784	4 / 1
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002725 C00031185	1 / 1
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00001228 C00030479	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00001213 C00001221	5 / 3
P14679	Tyrosinase	Oxidoreductase	C00003039 C00034452	4 / 2
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00001228 C00030479	2 / 2
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00019221 C00030479	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00000823 C00001221	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000155 C00000156	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00001221 C00001228	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00000155 C00000156	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001228 C00035062	1 / 1
P40763	Signal transducer and activator of transcription 3	Transcription Factor	C00034818	1 / 2
P12104	Fatty acid-binding protein, intestinal	Other cytosolic protein	C00030479	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001221	7 / 3
Q8TCC7	Solute carrier family 22 member 8	Antiporter	C00001231	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00034452	2 / 0
P39748	Flap endonuclease 1	Enzyme	C00001228	0 / 0
P14902	Indoleamine 2,3-dioxygenase 1	Enzyme	C00034452	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00019221	0 / 0
Q9UGP5	DNA polymerase lambda	Enzyme	C00001221	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00001228	2 / 2
Q4U2R8	Solute carrier family 22 member 6	Antiporter	C00001231	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001228	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00030479	0 / 0
P08183	Multidrug resistance protein 1	drug	C00030479	1 / 0
P40925	Malate dehydrogenase, cytoplasmic	Enzyme	C00019221	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00000814	0 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00034818	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00002740	2 / 0
P30556	Type-1 angiotensin II receptor	Angiotensin receptor	C00019221	1 / 1
P08047	Transcription factor Sp1	Unclassified protein	C00030479	0 / 0
P05413	Fatty acid-binding protein, heart	Other cytosolic protein	C00030479	0 / 0
Q05193	Dynamin-1	Structural	C00001228	0 / 0
O00167	Eyes absent homolog 2	Enzyme	C00002707	0 / 0
P42224	Signal transducer and activator of transcription 1-alpha/beta	Unclassified protein	C00034818	3 / 3
P15090	Fatty acid-binding protein, adipocyte	Other cytosolic protein	C00030479	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002725	1 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00035062	2 / 0
Q01469	Fatty acid-binding protein, epidermal	Other cytosolic protein	C00030479	0 / 0
P51692	Signal transducer and activator of transcription 5B	Unclassified protein	C00034818	1 / 1
Q9NSA0	Solute carrier family 22 member 11	Transporter	C00001231	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00034818	0 / 0

253 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001221 C00002725 C00003050 C00030479 C00037855
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000155 C00000823 C00002725 C00030479 C00037855
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00001213 C00001221 C00001231 C00001264
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000155 C00000156 C00002725 C00030479
581	BAX, BCL2L4	BCL2-associated X protein	C00000155 C00002725 C00030479 C00037855
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000357 C00000823 C00002725 C00003047
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000861 C00002725 C00003047 C00030479
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00001213 C00001221 C00001228 C00030479
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00001221 C00001228 C00001231 C00030479
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00002725 C00003047 C00037855
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00001221 C00002740 C00037855
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00000357 C00002725 C00003047
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000823 C00003047 C00037855
217	ALDH2, ALDH-E2, ALDHI, ALDM	aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3)	C00000357 C00030804 C00034452
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00000357 C00030804 C00030828
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001221 C00002725 C00030479
8989	TRPA1, ANKTM1, FEPS	transient receptor potential cation channel, subfamily A, member 1	C00000156 C00002725
199974	CYP4Z1, CYP4A20	cytochrome P450, family 4, subfamily Z, polypeptide 1 (EC:1.14.14.1)	C00001221 C00001228
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000823 C00002725
218	ALDH3A1, ALDH3, ALDHIII	aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)	C00000357 C00034452
221	ALDH3B1, ALDH4, ALDH7	aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5)	C00000357 C00034452
2554	GABRA1, ECA4, EJM, EJM5	gamma-aminobutyric acid (GABA) A receptor, alpha 1	C00035062 C00035341
388	RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6	ras homolog family member B	C00003050 C00035062
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00001264 C00030100
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00003047 C00003050
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00003047 C00030479
4852	NPY, PYY4	neuropeptide Y	C00000823 C00003047
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002725 C00030479
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00002725 C00030479
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00002725 C00003047
387	RHOA, ARH12, ARHA, RHO12, RHOH12	ras homolog family member A	C00003050 C00035062
2566	GABRG2, CAE2, ECA2, GEFSP3	gamma-aminobutyric acid (GABA) A receptor, gamma 2	C00035062 C00035341
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002725 C00037855
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00002725 C00037855
2561	GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	C00035062 C00035341
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00002725 C00003047
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00002725 C00003050
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00002725 C00003047
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00002725 C00003047
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00002725 C00003047
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00001213 C00001221
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000155 C00002725
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00002725 C00030479
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00002725 C00030479
9817	KEAP1, INrf2, KLHL19	kelch-like ECH-associated protein 1	C00002725 C00003050
162514	TRPV3, OLMS, VRL3	transient receptor potential cation channel, subfamily V, member 3	C00000155 C00000156
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00002725 C00003047
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002725 C00003047
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00030479 C00037855
3251	HPRT1, HGPRT, HPRT	hypoxanthine phosphoribosyltransferase 1 (EC:2.4.2.8)	C00002725 C00037855
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00002725 C00037855
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00002725 C00003047
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00002725 C00037855
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00030479
51232	CRIM1, CRIM-1, S52	cysteine rich transmembrane BMP regulator 1 (chordin-like)	C00002725
1399	CRKL	v-crk avian sarcoma virus CT10 oncogene homolog-like	C00002725
1490	CTGF, CCN2, HCS24, IGFBP8, NOV2	connective tissue growth factor	C00002725
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00002725
1581	CYP7A1, CP7A, CYP7, CYPVII	cytochrome P450, family 7, subfamily A, polypeptide 1 (EC:1.14.13.17)	C00002725
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00002725
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00002725
56616	DIABLO, DFNA64, SMAC	diablo, IAP-binding mitochondrial protein	C00002725
2039	DMTN, DMT, EPB49	dematin actin binding protein	C00002725
1789	DNMT3B, ICF, ICF1, M.HsaIIIB	DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37)	C00002725
1848	DUSP6, HH19, MKP3, PYST1	dual specificity phosphatase 6 (EC:3.1.3.16 3.1.3.48)	C00002725
83658	DYNLRB1, BITH, BLP, DNCL2A, DNLC2A, ROBLD1	dynein, light chain, roadblock-type 1	C00002725
55840	EAF2, BM040, TRAITS, U19	ELL associated factor 2	C00002725
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00002725
2034	EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73	endothelial PAS domain protein 1	C00002725
2150	F2RL1, GPR11, PAR2	coagulation factor II (thrombin) receptor-like 1	C00002725
2213	FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2	Fc fragment of IgG, low affinity IIb, receptor (CD32)	C00002725
9103	FCGR2C, CD32, CD32C, CDW32, FCG2, FCRIIC, IGFR2	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	C00002725
2263	FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25	fibroblast growth factor receptor 2 (EC:2.7.10.1)	C00002725
2330	FMO5	flavin containing monooxygenase 5 (EC:1.14.13.8)	C00002725
1385	CREB1, CREB	cAMP responsive element binding protein 1	C00002725
2495	FTH1, FHC, FTH, FTHL6, PIG15, PLIF	ferritin, heavy polypeptide 1 (EC:1.16.3.1)	C00002725
2535	FZD2, Fz2, fz-2, fzE2, hFz2	frizzled family receptor 2	C00002725
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00002725
1294	COL7A1, EBD1, EBDCT, EBR1	collagen, type VII, alpha 1	C00002725
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00002725
2745	GLRX, GRX, GRX1	glutaredoxin (thioltransferase) (EC:1.8.4.1)	C00002725
2844	GPR21	G protein-coupled receptor 21	C00002725
2877	GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2	glutathione peroxidase 2 (gastrointestinal) (EC:1.11.1.9)	C00002725
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00002725
4848	CNOT2, CDC36, NOT2, NOT2H	CCR4-NOT transcription complex, subunit 2	C00002725
3077	HFE, HFE1, HH, HLA-H, MVCD7, TFQTL2	hemochromatosis	C00002725
1196	CLK2, hCLK2	CDC-like kinase 2 (EC:2.7.12.1)	C00002725
3304	HSPA1B, HSP70-1B, HSP70-2	heat shock 70kDa protein 1B	C00002725
10553	HTATIP2, CC3, SDR44U1, TIP30	HIV-1 Tat interactive protein 2, 30kDa (EC:1.1.1.-)	C00002725
27429	HTRA2, OMI, PARK13, PRSS25	HtrA serine peptidase 2 (EC:3.4.21.108)	C00002725
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002725
3429	IFI27, FAM14D, ISG12, ISG12A, P27	interferon, alpha-inducible protein 27	C00002725
10964	IFI44L, C1orf29	interferon-induced protein 44-like	C00002725
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00002725
3575	IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA	interleukin 7 receptor	C00002725
1066	CES1, ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1	carboxylesterase 1 (EC:3.1.1.1 3.1.1.56)	C00002725
994	CDC25B	cell division cycle 25B (EC:3.1.3.48)	C00002725
22801	ITGA11, HsT18964	integrin, alpha 11	C00002725
942	CD86, B7-2, B7.2, B70, CD28LG2, LAB72	CD86 molecule	C00002725
3727	JUND, AP-1	jun D proto-oncogene	C00002725
29126	CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1	CD274 molecule	C00002725
10186	LHFP	lipoma HMGIC fusion partner (EC:3.6.5.4)	C00002725
29995	LMCD1	LIM and cysteine-rich domains 1	C00002725
29967	LRP12, ST7	low density lipoprotein receptor-related protein 12	C00002725
4049	LTA, LT, TNFB, TNFSF1	lymphotoxin alpha	C00002725
79917	MAGIX, JM10, PDZX	MAGI family member, X-linked	C00002725
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00002725
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002725
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00002725
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002725
91057	CCDC34, NY-REN-41, RAMA3	coiled-coil domain containing 34	C00002725
8550	MAPKAPK5, MAPKAP-K5, MK-5, MK5, PRAK	mitogen-activated protein kinase-activated protein kinase 5 (EC:2.7.11.1)	C00002725
57787	MARK4, MARK4L, MARK4S, MARKL1, MARKL1L, PAR-1D	MAP/microtubule affinity-regulating kinase 4 (EC:2.7.11.1)	C00002725
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00002725
834	CASP1, ICE, IL1BC, P45	caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36)	C00002725
4599	MX1, IFI-78K, IFI78, MX, MxA	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	C00002725
100132406	NBPF10, AB6, AG1, NBPF9	neuroblastoma breakpoint family, member 10	C00002725
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00002725
637	BID, FP497	BH3 interacting domain death agonist	C00002725
55973	BCAP29, BAP29	B-cell receptor-associated protein 29	C00002725
22981	NINL, NLP, dJ691N24.1	ninein-like	C00002725
4854	NOTCH3, CADASIL, CASIL, IMF2	notch 3	C00002725
23250	ATP11A, ATPIH, ATPIS	ATPase, class VI, type 11A (EC:3.6.3.1)	C00002725
56666	PANX2, PX2, hPANX2	pannexin 2	C00002725
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00002725
5140	PDE3B, HcGIP1, cGIPDE1	phosphodiesterase 3B, cGMP-inhibited (EC:3.1.4.17)	C00002725
7262	PHLDA2, BRW1C, BWR1C, HLDA2, IPL, TSSC3	pleckstrin homology-like domain, family A, member 2	C00002725
8544	PIR	pirin (iron-binding nuclear protein) (EC:1.13.11.24)	C00002725
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00002725
5447	POR, CPR, CYPOR, P450R	P450 (cytochrome) oxidoreductase (EC:1.6.2.4)	C00002725
8496	PPFIBP1, L2, SGT2, hSGT2, hSgt2p	PTPRF interacting protein, binding protein 1 (liprin beta 1)	C00002725
5514	PPP1R10, CAT53, FB19, PNUTS, PP1R10, R111, p99	protein phosphatase 1, regulatory subunit 10	C00002725
11107	PRDM5, BCS2, PFM2	PR domain containing 5	C00002725
57636	ARHGAP23	Rho GTPase activating protein 23	C00002725
57679	ALS2, ALS2CR6, ALSJ, IAHSP, PLSJ	amyotrophic lateral sclerosis 2 (juvenile)	C00002725
146760	RTN4RL1, NGRH2, NgR3	reticulon 4 receptor-like 1	C00002725
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00002725
6444	SGCD, 35DAG, CMD1L, DAGD, SG-delta, SGCDP, SGD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	C00002725
6563	SLC14A1, HUT11, HsT1341, JK, RACH1, RACH2, UT-B1, UT1, UTE	solute carrier family 14 (urea transporter), member 1	C00002725
6506	SLC1A2, EAAT2, GLT-1	solute carrier family 1 (glial high affinity glutamate transporter), member 2	C00002725
115111	SLC26A7, SUT2	solute carrier family 26 (anion exchanger), member 7	C00002725
114134	SLC2A13, HMIT	solute carrier family 2 (facilitated glucose transporter), member 13	C00002725
11046	SLC35D2, HFRC1, SQV7L, UGTrel8, hfrc	solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2	C00002725
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00002725
6546	SLC8A1, NCX1	solute carrier family 8 (sodium/calcium exchanger), member 1	C00002725
4087	SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2	SMAD family member 2	C00002725
28966	SNX24, PRO1284	sorting nexin 24	C00002725
9295	SRSF11, NET2, SFRS11, dJ677H15.2, p54	serine/arginine-rich splicing factor 11	C00002725
140809	SRXN1, C20orf139, Npn3, SRX, SRX1	sulfiredoxin 1 (EC:1.8.98.2)	C00002725
27067	STAU2, 39K2, 39K3	staufen double-stranded RNA binding protein 2	C00002725
8428	STK24, MST3, MST3B, STE20, STK3	serine/threonine kinase 24 (EC:2.7.11.1)	C00002725
51684	SUFU, PRO1280, SUFUH, SUFUXL	suppressor of fused homolog (Drosophila)	C00002725
6915	TBXA2R, BDPLT13, TXA2-R	thromboxane A2 receptor	C00002725
7041	TGFB1I1, ARA55, HIC-5, HIC5, TSC-5	transforming growth factor beta 1 induced transcript 1	C00002725
55258	THNSL2, SOFAT, THS2, TSH2	threonine synthase-like 2 (S. cerevisiae) (EC:4.2.3.-)	C00002725
7099	TLR4, ARMD10, CD284, TLR-4, TOLL	toll-like receptor 4	C00002725
133	ADM, AM	adrenomedullin	C00002725
27242	TNFRSF21, BM-018, CD358, DR6	tumor necrosis factor receptor superfamily, member 21	C00002725
10626	TRIM16, EBBP	tripartite motif containing 16	C00002725
132	ADK, AK	adenosine kinase (EC:2.7.1.20)	C00002725
7273	TTN, CMD1G, CMH9, CMPD4, EOMFC, HMERF, LGMD2J, MYLK5, TMD	titin (EC:2.7.11.1)	C00002725
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00002725
7321	UBE2D1, E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A	ubiquitin-conjugating enzyme E2D 1 (EC:6.3.2.19)	C00002725
7360	UGP2, UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2, pHC379	UDP-glucose pyrophosphorylase 2 (EC:2.7.7.9)	C00002725
7374	UNG, DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2	uracil-DNA glycosylase (EC:3.2.2.27)	C00002725
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00002725
340481	ZDHHC21, 9130404H11Rik, DHHC-21, DHHC21, DNZ1, HSPC097	zinc finger, DHHC-type containing 21 (EC:2.3.1.225)	C00002725
79973	ZNF442	zinc finger protein 442	C00002725
440515	ZNF506	zinc finger protein 506	C00002725
51193	ZNF639, 6230400O18Rik, ANC-2H01, ANC_2H01, ZASC1	zinc finger protein 639	C00002725
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00030830
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00003047
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00003047
1028	CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	C00003047
1030	CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	C00003047
1447	CSN2, CASB	casein beta	C00003047
1509	CTSD, CLN10, CPSD	cathepsin D (EC:3.4.23.5)	C00003047
8745	ADAM23, MDC-3, MDC3	ADAM metallopeptidase domain 23	C00002725
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003047
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00003047
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00003047
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00003047
3297	HSF1, HSTF1	heat shock transcription factor 1	C00003047
3320	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	C00003047
3308	HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY	heat shock 70kDa protein 4	C00003047
3316	HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP	heat shock 27kDa protein 2	C00003047
3398	ID2, GIG8, ID2A, ID2H, bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	C00003047
8850	KAT2B, CAF, P, P/CAF, PCAF	K(lysine) acetyltransferase 2B (EC:2.3.1.48)	C00003047
100124292			C00003047
145447	ABHD12B, BEM46L3, C14orf29, c14_5314	abhydrolase domain containing 12B	C00002725
7471	WNT1, BMND16, INT1, OI15	wingless-type MMTV integration site family, member 1	C00003047
26118	WSB1, SWIP1, WSB-1	WD repeat and SOCS box containing 1	C00003047
1135	CHRNA2	cholinergic receptor, nicotinic, alpha 2 (neuronal)	C00035784
1143	CHRNB4	cholinergic receptor, nicotinic, beta 4 (neuronal)	C00035784
8714	ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	C00002725
501	ALDH7A1, ATQ1, EPD, PDE	aldehyde dehydrogenase 7 family, member A1 (EC:1.2.1.3 1.2.1.8 1.2.1.31)	C00000357
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00001221
1579	CYP4A11, CP4Y, CYP4A2, CYP4AII	cytochrome P450, family 4, subfamily A, polypeptide 11 (EC:1.14.15.3)	C00001221
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00000823
64127	NOD2, ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1	nucleotide-binding oligomerization domain containing 2	C00001221
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00002740
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002740
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00019221
9076	CLDN1, CLD1, ILVASC, SEMP1	claudin 1	C00001213
1555	CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450	cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1)	C00003050
23764	MAFF, U-MAF, hMafF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	C00003050
5906	RAP1A, KREV-1, KREV1, RAP1, SMGP21	RAP1A, member of RAS oncogene family	C00003050
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00019221
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00000156
9131	AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8	apoptosis-inducing factor, mitochondrion-associated, 1	C00000155
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000155
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000155
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000155
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000155
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000155
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00000155
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00030479
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00019221
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00030479
1390	CREM, CREM-2, ICER, hCREM-2	cAMP responsive element modulator	C00002725
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00030479
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00030479
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00030479
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00030479
3481	IGF2, C11orf43, IGF-II, PP9974	insulin-like growth factor 2 (somatomedin A)	C00030479
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00030479
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00030479
4493	MT1E, MT1, MTD	metallothionein 1E	C00030479
4494	MT1F, MT1	metallothionein 1F	C00030479
4496	MT1H, MT-0, MT-1H, MT-IH, MT1	metallothionein 1H	C00030479
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00030479
4502	MT2A, MT2	metallothionein 2A	C00030479
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00030479
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00030479
29893	PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP	PSMC3 interacting protein	C00030479
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00030479
23216	TBC1D1, TBC, TBC1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	C00030479
7351	UCP2, BMIQ4, SLC25A8, UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	C00030479
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00037855
847	CAT	catalase (EC:1.11.1.6)	C00037855
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00037855
1230	CCR1, CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1	chemokine (C-C motif) receptor 1	C00037855
2052	EPHX1, EPHX, EPOX, HYL1, MEH	epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9)	C00037855
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00037855
2952	GSTT1	glutathione S-transferase theta 1 (EC:2.5.1.18)	C00037855
3303	HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1	heat shock 70kDa protein 1A	C00037855
3937	LCP2, SLP-76, SLP76	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	C00037855
4968	OGG1, HMMH, HOGG1, MUTM, OGH1	8-oxoguanine DNA glycosylase (EC:4.2.99.18)	C00037855
5894	RAF1, CRAF, NS5, Raf-1, c-Raf	v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1)	C00037855
7042	TGFB2, LDS4, TGF-beta2	transforming growth factor, beta 2	C00037855
7049	TGFBR3, BGCAN, betaglycan	transforming growth factor, beta receptor III	C00037855
7515	XRCC1, RCC	X-ray repair complementing defective repair in Chinese hamster cells 1	C00037855
7517	XRCC3, CMM6	X-ray repair complementing defective repair in Chinese hamster cells 3	C00037855

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