Anthemis aciphylla BOISS.var.discoidea BOISS

• Index
• Plant Species
• Metabolite list (84)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Anthemis aciphylla BOISS.var.discoidea BOISS
Genus	Anthemis
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Anthemis
Linked NCBI taxonomy ID	99027
Linked level	genus

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (84)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00030958	Pentacosane					No. 115
C00030471	Heptacosane					No. 115
C00001260	Nonacosane	CHEMBL428955	C047577			No. 115
C00030479	Hexadecanoic acid / n-Hexadecanoic acid	CHEMBL82293	D019308	16 / 8 / 8	35 / 1	No. 184	No. 68
C00003161	Ledol / (+)-Ledol	CHEMBL2171207		1 / 2 / 3		No. 197	No. 38
C00020065	alpha-Cadinol / (-)-alpha-Cadinol	CHEMBL486795				No. 205	No. 38
C00030345	gamma-Cadinene		C054278			No. 283	No. 39
C00029546	Varamol 106 / 4-Vinyl guaiacol		C014245			No. 310	No. 6
C00021884	beta-Bourbonene / (E)-beta-Bourbonene					No. 333	No. 38
C00003118	Copaene / alpha-Copaene / (-)-alpha-Copaene					No. 333	No. 38
C00012813	Kongol / Selin-11-en-4alpha-ol / 5alpha,7alphaH-Eudesm-11(13)en-4alpha-ol / [1R-(1alpha,4abeta,7beta,8aalpha)]-decahydro-1,4a-dimethyl-7-(1-methylethenyl)-1-naphthalenol	CHEMBL481844 CHEMBL505457				No. 398	No. 38
C00029350	Z-beta-Farnesene / (Z)-beta-Farnesene / beta-cis-Farnesene / cis-beta-Farnesene					No. 404	No. 38
C00011617	AR-Curcumene / (R)-(-)-alpha-Curcumene	CHEMBL469717				No. 456	No. 38
C00030803	Myrtenal		C061545			No. 476	No. 35
C00000816	beta-Pinene	CHEMBL501351	C010789			No. 476	No. 35
C00000863	R-(+)-trans-Verbenol					No. 476	No. 35
C00000829	trans-Pinocarveol					No. 476	No. 35
C00029977	cis-Verbenol					No. 476	No. 35
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00012483	Betula pubescens / Caryophyllene oxide / trans-Caryophyllene oxide / beta-Caryophyllene epoxide / (-)-Epoxydihydrocaryophyllene / 6,7-Epoxy-3(15)-caryophyllene / (-)-beta-Caryophyllene epoxide / 4beta,5alpha-Epoxycaryophyllene / Caryophyllene 4beta,5alpha-epoxide	CHEMBL399036 CHEMBL508894 CHEMBL479134 CHEMBL1513806 CHEMBL1553274		3 / 1 / 3		No. 500
C00030959	Pentadecanal		C003061			No. 599
C00032309	Tetradecanol / 1-Tetradecanol	CHEMBL24022	C020940	1 / 0 / 0		No. 599
C00030480	Hexahydrofarnesyl acetone / 6,10,14-Trimethyl-2-pentadecanone		C014584			No. 641	No. 38
C00003028	Borneol / (+/-)-Borneol	CHEMBL296404 CHEMBL486208 CHEMBL1097205 CHEMBL1968981		8 / 5 / 1		No. 649	No. 35
C00012425	Bicyclogermacren / Bicyclogermacrene / (+)-Bicyclogermacrene	CHEMBL509566				No. 699	No. 38
C00007242	beta-Bisabolene / l-beta-Bisabolene / (-)-beta-Bisabolene	CHEMBL444389 CHEMBL1077088 CHEMBL2001434				No. 701	No. 38
C00032409	Tricosane					No. 732
C00029422	1-Octadecanol / Octadecan-1-ol	CHEMBL24640	C009316	3 / 11 / 10		No. 732
C00030154	Okimelanolure / Dodecyl acetate / n-Dodecyl acetate		C044215			No. 793
C00030100	Decanol / 1-Decanol / n-Decanol	CHEMBL25363	C029383	1 / 0 / 0	1 / 0	No. 877
C00003047	Linalool / (R)-linalool / (R)-(-)-3,7-Dimethyl-1,6-octadien-3-ol	CHEMBL25306 CHEMBL235672	C018584	6 / 8 / 2	35 / 4	No. 958	No. 34
C00000155	Thymol	CHEMBL29411	D013943	9 / 17 / 14	12 / 0	No. 969	No. 35
C00000156	Carvacrol	CHEMBL281202	C073316	10 / 6 / 1	4 / 2	No. 969	No. 35
C00029674	alpha-Terpineol	CHEMBL447597 CHEMBL449810	C016775	3 / 16 / 11		No. 983	No. 35
C00001231	Caprylic acid / Octanoic acid / n-Octanoic acid	CHEMBL324846	C031492	10 / 14 / 13	2 / 1	No. 1141	No. 68
C00001213	Capric acid / Decanoic acid / n-Decanoic acid	CHEMBL107498	C031071	8 / 11 / 6	4 / 0	No. 1141	No. 68
C00001221	Lauric acid / Docosanoic acid / n-Dodecanoic acid	CHEMBL108766	C030358	19 / 25 / 14	11 / 0	No. 1141	No. 68
C00001228	Myristic acid / Tetradecanoic acid / n-Tetradecanoic acid	CHEMBL111077	D019814	17 / 9 / 10	3 / 0	No. 1141	No. 68
C00030829	Pelargonic acid / n-Nonanoic acid	CHEMBL108436	C008776	4 / 4 / 2	3 / 1	No. 1141	No. 68
C00000154	p-trans-Menth-2-en-1-ol					No. 1151
C00029973	cis-p-Menth-2-en-1-ol					No. 1151
C00031258	Sabinene / 4(10)-Thujene	CHEMBL452687	C035127			No. 1343	No. 35
C00030347	gamma-Dodecalactone	CHEMBL195215 CHEMBL1269378		1 / 0 / 0		No. 1374
C00007636	delta-Cadinene	CHEMBL445759				No. 1524	No. 39
C00029971	cis-Carveol	CHEMBL1385229 CHEMBL1907992 CHEMBL1908058		6 / 15 / 40		No. 1555	No. 35
C00000814	(-)-trans-Carveol	CHEMBL1385229 CHEMBL1907992 CHEMBL1908058		6 / 15 / 40		No. 1555	No. 35
C00000149	Spathulenol	CHEMBL518542 CHEMBL1774433	C013258			No. 1603
C00029335	beta-Ocimene / E-beta-Ocimene / (E)-beta-Ocimene		C443996			No. 1698	No. 34
C00029351	Z-beta-Ocimene / cis-beta-Ocimene / (Z)-beta-Ocimene					No. 1698	No. 34
C00001264	Octanol / n-Octanol / 1-Octanol / Octan-1-ol	CHEMBL26215	D020003	5 / 6 / 5	2 / 0	No. 1749
C00030830	Nonanol / n-Nonanol	CHEMBL24563	C014713		1 / 0	No. 1749
C00030346	gamma-Curcumene					No. 1788	No. 38
C00010872	beta-Phellandrene / (+/-)-beta-Phellandrene	CHEMBL444254	C058582			No. 1898	No. 35
C00030828	Nonanal / n-Nonanal		C008664		1 / 1	No. 1993
C00030099	Decanal / Capraldehyde		C021170		2 / 0	No. 1993
C00031273	Salicylaldehyde	CHEMBL108925	C013243	2 / 4 / 2		No. 2076
C00030881	Octyl 2-methylbutyrate					No. 2098
C00029330	(E)-2-Decenal	CHEMBL507518				No. 2140
C00029331	(E)-2-Nonenal / trans-2-Nonenal	CHEMBL450072		1 / 0 / 0		No. 2140
C00029332	(E)-2-Undecenal / trans-2-Undecenal	CHEMBL451328				No. 2140
C00003040	p-Cymene	CHEMBL442915	C007210			No. 2172	No. 35
C00029997	(E,Z)-2,4-Decadienal / trans-2,cis-4-Decadienal	CHEMBL443949		8 / 12 / 42		No. 2201
C00029341	(E,E)-2,4-Decadienal / 2-trans,4-trans-Decadienal	CHEMBL443949		8 / 12 / 42		No. 2201
C00029544	4-Terpineol / Terpin-4-ol / Terpineol-4 / Terpinen-4-ol	CHEMBL507795	C034019	1 / 3 / 0		No. 2215
C00003032	Chrysanthenone					No. 2232	No. 35
C00000853	Myrcene	CHEMBL455491	C008574	3 / 3 / 3		No. 2285	No. 34
C00003204	l-Zingiberene / (-)-Zingiberene / alpha-Zingiberene	CHEMBL479020				No. 2380	No. 38
C00003060	alpha-Terpinene					No. 2468	No. 35
C00003061	gamma-Terpinene / 1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene	CHEMBL449693	C018669			No. 2468	No. 35
C00029336	(E)-Geranyl acetone / trans-Geranylacetone					No. 2572
C00030525	Isofaurinone					No. 2633
C00011720	Germacrene D / (-)-Germacrene D	CHEMBL105432 CHEMBL1836650				No. 2639	No. 38
C00029316	(2E)-Octenal / (E)-2-Octenal / trans-Oct-2-en-1-al	CHEMBL448058				No. 2883
C00030880	Octanal / n-Octanal	CHEMBL18407	C031639		2 / 0	No. 3593
C00000357	Hexanal	CHEMBL280331	C010463		7 / 0	No. 3593
C00000861	Terpinolene	CHEMBL454697	C027009		1 / 0	No. 3725
C00021428	Mintketone / Salvial-4(14)-en-1-one					No. 3830
C00030376	Geranyl isovalerate					No. 4019
C00000136	1,8-Cineole	CHEMBL485259 CHEMBL1397305		99 / 57 / 50		No. 5413	No. 35
C00029345	(Z)-3-Hexen-1-yl benzoate					No. 6091
C00030882	Octyl isovalerate / 2-Octyl 3-methyl butyrate					No. 6522
C00029667	alpha-Campholene aldehyde					No. 6876
C00031068	p-Mentha-1,5-dien-8-ol					No. 7280
C00030933	p-Cymen-8-ol					No. 8611

Human Protein / Gene in interactions

153 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000155 C00000156 C00000814 C00001213 C00001221 C00003028 C00003047 C00029544 C00029674 C00029971	3 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000136 C00000805 C00000814 C00000853 C00001213 C00001221 C00001231 C00029341 C00029971 C00029997	3 / 2
O75496	Geminin	Unclassified protein	C00000136 C00001213 C00001228 C00001231 C00029422 C00030479 C00030829	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000155 C00000156 C00000814 C00003028 C00003047 C00029674 C00029971	5 / 1
P04150	Glucocorticoid receptor	NR3C1	C00000136 C00000853 C00001213 C00001231 C00001264 C00030479	0 / 1
Q96RI1	Bile acid receptor	NR1H4	C00000853 C00001221 C00001228 C00030100 C00030479 C00032309	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000156 C00001213 C00001221 C00001228 C00001231 C00003028	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805 C00001213 C00001221 C00029341 C00029997	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000155 C00000156 C00000814 C00003028 C00029971	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000156 C00001213 C00001221 C00001228 C00001231	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00001221 C00001231 C00001264 C00029341 C00029997	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000136 C00001221 C00001228 C00001264 C00003047	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000136 C00000155 C00001231 C00029422 C00029674	11 / 10
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00000155 C00000156 C00003028 C00003047	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00000814 C00029341 C00029971 C00029997	7 / 37
P10828	Thyroid hormone receptor beta	NR1A2	C00001221 C00001264 C00003047 C00030829	3 / 1
P10275	Androgen receptor	NR3C4	C00000136 C00001221 C00030479	3 / 4
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00000155 C00000156 C00003028	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000155 C00000156 C00003028	0 / 0
P03372	Estrogen receptor	NR3A1	C00000136 C00001221 C00030479	1 / 1
P11473	Vitamin D3 receptor	NR1I1	C00001228 C00029341 C00029997	2 / 3
P10145	Interleukin-8	Secreted protein	C00001221 C00029341 C00029997	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000136 C00030347	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000136 C00000805	0 / 0
O75762	Transient receptor potential cation channel subfamily A member 1	Unclassified protein	C00000155 C00000156	1 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00029341 C00029997	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00001213 C00001221	5 / 3
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00001228 C00030479	2 / 2
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000136 C00012483	1 / 1
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00000814 C00029971	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000136 C00012483	0 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00001221 C00001228	0 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00029331 C00031273	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000136 C00001221	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00029341 C00029997	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000136 C00000155	0 / 3
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00001228 C00030479	0 / 0
O60603	Toll-like receptor 2	Membrane receptor	C00001228 C00030479	1 / 1
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000136 C00000156	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001228 C00030829	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000136 C00012483	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001264	3 / 3
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000136	1 / 8
P11387	DNA topoisomerase 1	Isomerase	C00030479	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000136	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00000136	2 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000136	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000136	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000136	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000136	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000136	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000136	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000136	1 / 1
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001228	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000136	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000136	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000136	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00001228	2 / 2
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000136	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00001228	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001228	0 / 0
P08183	Multidrug resistance protein 1	drug	C00030479	1 / 0
Q8TCC7	Solute carrier family 22 member 8	Antiporter	C00001231	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000136	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000136	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000136	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000136	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000136	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000136	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000136	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000136	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000136	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000136	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000136	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000136	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000136	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000136	1 / 0
P12104	Fatty acid-binding protein, intestinal	Other cytosolic protein	C00030479	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000136	0 / 0
P08311	Cathepsin G	S1A	C00000136	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000136	1 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000136	1 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000136	0 / 0
P03956	Interstitial collagenase	M10A	C00000136	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000136	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001221	7 / 3
Q9UGP5	DNA polymerase lambda	Enzyme	C00001221	0 / 0
Q4U2R8	Solute carrier family 22 member 6	Antiporter	C00001231	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00000136	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000136	1 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00030479	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000136	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000136	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000136	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000136	1 / 2
P14679	Tyrosinase	Oxidoreductase	C00031273	4 / 2
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000136	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000136	2 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00001221	0 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000136	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000136	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000136	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000136	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000136	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000136	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00030479	0 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00000136	0 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00003161	2 / 3
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000136	1 / 0
P05413	Fatty acid-binding protein, heart	Other cytosolic protein	C00030479	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000136	2 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00030829	0 / 0
P55055	Oxysterols receptor LXR-beta	NR1H3	C00000136	0 / 0
Q01469	Fatty acid-binding protein, epidermal	Other cytosolic protein	C00030479	0 / 0
P16662	UDP-glucuronosyltransferase 2B7	Enzyme	C00003028	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000136	2 / 2
P27361	Mitogen-activated protein kinase 3	Erk	C00000136	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000136	0 / 0
P29466	Caspase-1	C14	C00000136	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000136	0 / 0
Q05193	Dynamin-1	Structural	C00001228	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000136	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000136	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000136	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000136	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000136	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000136	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000136	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000136	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000136	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00003047	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000136	0 / 0
P15090	Fatty acid-binding protein, adipocyte	Other cytosolic protein	C00030479	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000136	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00029422	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000136	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000136	4 / 3
P08246	Neutrophil elastase	S1A	C00000136	2 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000136	2 / 2
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000136	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000136	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000136	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000136	0 / 0
Q7Z2W7	Transient receptor potential cation channel subfamily M member 8	Unclassified protein	C00000136	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000136	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000136	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00000136	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000136	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00001221	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000136	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001228	1 / 1
Q9NSA0	Solute carrier family 22 member 11	Transporter	C00001231	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000136	1 / 0

95 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00001221 C00001228 C00001231 C00030479 C00030829
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00001213 C00001221 C00001231 C00001264 C00030829
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00000357 C00030099 C00030828 C00030880
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00001213 C00001221 C00001228 C00030479
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000861 C00003047 C00030479
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000155 C00000156 C00030479
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000357 C00003047
162514	TRPV3, OLMS, VRL3	transient receptor potential cation channel, subfamily V, member 3	C00000155 C00000156
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00000357 C00003047
221	ALDH3B1, ALDH4, ALDH7	aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5)	C00000357 C00030880
581	BAX, BCL2L4	BCL2-associated X protein	C00000155 C00030479
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00001213 C00001221
217	ALDH2, ALDH-E2, ALDHI, ALDM	aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3)	C00000357 C00030099
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001221 C00030479
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000155 C00030479
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001221 C00030479
199974	CYP4Z1, CYP4A20	cytochrome P450, family 4, subfamily Z, polypeptide 1 (EC:1.14.14.1)	C00001221 C00001228
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00001264 C00030100
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00003047 C00030479
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00030479
1447	CSN2, CASB	casein beta	C00003047
1509	CTSD, CLN10, CPSD	cathepsin D (EC:3.4.23.5)	C00003047
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00003047
1028	CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	C00003047
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003047
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00003047
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00003047
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00003047
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00003047
3297	HSF1, HSTF1	heat shock transcription factor 1	C00003047
3320	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	C00003047
3308	HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY	heat shock 70kDa protein 4	C00003047
3316	HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP	heat shock 27kDa protein 2	C00003047
3398	ID2, GIG8, ID2A, ID2H, bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	C00003047
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00003047
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00003047
8850	KAT2B, CAF, P, P/CAF, PCAF	K(lysine) acetyltransferase 2B (EC:2.3.1.48)	C00003047
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00003047
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00003047
4852	NPY, PYY4	neuropeptide Y	C00003047
100124292			C00003047
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00003047
7471	WNT1, BMND16, INT1, OI15	wingless-type MMTV integration site family, member 1	C00003047
26118	WSB1, SWIP1, WSB-1	WD repeat and SOCS box containing 1	C00003047
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00003047
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00001221
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00001221
1579	CYP4A11, CP4Y, CYP4A2, CYP4AII	cytochrome P450, family 4, subfamily A, polypeptide 11 (EC:1.14.15.3)	C00001221
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00003047
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00003047
64127	NOD2, ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1	nucleotide-binding oligomerization domain containing 2	C00001221
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00003047
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00003047
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00003047
9076	CLDN1, CLD1, ILVASC, SEMP1	claudin 1	C00001213
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00030830
8989	TRPA1, ANKTM1, FEPS	transient receptor potential cation channel, subfamily A, member 1	C00000156
501	ALDH7A1, ATQ1, EPD, PDE	aldehyde dehydrogenase 7 family, member A1 (EC:1.2.1.3 1.2.1.8 1.2.1.31)	C00000357
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00000156
9131	AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8	apoptosis-inducing factor, mitochondrion-associated, 1	C00000155
218	ALDH3A1, ALDH3, ALDHIII	aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)	C00000357
942	CD86, B7-2, B7.2, B70, CD28LG2, LAB72	CD86 molecule	C00030829
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000155
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000155
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000155
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000155
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000155
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000155
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00000155
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00030479
1030	CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	C00003047
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00030479
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00030479
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00030479
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00030479
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00030479
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00030479
3481	IGF2, C11orf43, IGF-II, PP9974	insulin-like growth factor 2 (somatomedin A)	C00030479
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00030479
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00030479
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00030479
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00030479
4493	MT1E, MT1, MTD	metallothionein 1E	C00030479
4494	MT1F, MT1	metallothionein 1F	C00030479
4496	MT1H, MT-0, MT-1H, MT-IH, MT1	metallothionein 1H	C00030479
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00030479
4502	MT2A, MT2	metallothionein 2A	C00030479
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00030479
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00030479
29893	PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP	PSMC3 interacting protein	C00030479
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00030479
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00030479
23216	TBC1D1, TBC, TBC1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	C00030479
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00030479
7351	UCP2, BMIQ4, SLC25A8, UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	C00030479

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Diseases related to proteins in ChEMBL interactions

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