PCIDB

KNApSAcK Metabolite C00030829

Metabolite

KNApSAcK Entry

id C00030829
Name Pelargonic acid / n-Nonanoic acid
CAS RN 112-05-0
Standard InChI InChI=1S/C9H18O2/c1-2-3-4-5-6-7-8-9(10)11/h2-8H2,1H3,(H,10,11)
Standard InChI (Main Layer) InChI=1S/C9H18O2/c1-2-3-4-5-6-7-8-9(10)11/h2-8H2,1H3,(H,10,11)

Cluster

Phytochemical cluster No. 68
KCF-S cluster No. 1141

Link

ChEMBL

By standard InChI CHEMBL108436
By standard InChI Main Layer CHEMBL108436

KEGG

By LinkDB C01601

CTD

By CAS RN C008776

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL108436 CHEMBL1794585 (1)
0 / 0
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL108436 CHEMBL1794561 (1)
3 / 1
O75496 Geminin Unclassified protein CHEMBL108436 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL108436 CHEMBL2354287 (1)
1 / 1

CTD interaction (3)

compound gene gene name gene description interaction interaction type form reference
pmid
C008776 128 ADH5
ADH-3
ADHX
FALDH
FDH
GSH-FDH
GSNOR
alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284) pelargonic acid inhibits the reaction [ADH5 protein results in increased reduction of S-Nitrosoglutathione] decreases reaction
/ increases reduction
protein 19428350
C008776 942 CD86
B7-2
B7.2
B70
CD28LG2
LAB72
CD86 molecule pelargonic acid results in increased expression of CD86 protein increases expression
protein 19665512
C008776 5465 PPARA
NR1C1
PPAR
PPARalpha
hPPAR
peroxisome proliferator-activated receptor alpha pelargonic acid results in increased activity of PPARA protein increases activity
protein 23391484

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (2)

KEGG disease name UniProt
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)

Diseases related to CTD interactions

1 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D011041 C008776 Poisoning marker/mechanism
23391484