PCIDB

KNApSAcK Metabolite C00000424

Metabolite

KNApSAcK Entry

id C00000424
Name 12-HETE / 12-Hydroxyarachidonic acid
CAS RN 82337-46-0
Standard InChI InChI=1S/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+/t19-/m1/s1
Standard InChI (Main Layer) InChI=1S/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)

Cluster

Phytochemical cluster No. 68
KCF-S cluster No. 300

Link

ChEMBL

By standard InChI CHEMBL1435825
By standard InChI Main Layer CHEMBL1435825 CHEMBL1526258

KEGG

By LinkDB C14822

CTD

By CAS RN

Species

Summary

Plant class

class name count
Liliopsida 1

Family

family name count
Corallinaceae 1
Poaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Lithothamnion corallioides 48598 Corallinaceae Eukaryota
Zea mays 4577 Poaceae Liliopsida Viridiplantae

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL1435825 CHEMBL1526258 CHEMBL1738442 (2)
0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL1435825 CHEMBL1613933 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL1435825 CHEMBL1613933 (1)
1 / 6

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (1)

OMIM preferred title UniProt
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196

KEGG DISEASE (4)

KEGG disease name UniProt
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)