Lithothamnion corallioides

• Index
• Plant Species
• Metabolite list (14)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Lithothamnion corallioides
Genus	Lithothamnion
Family	Hapalidiaceae
Kingdom

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Lithothamnion
Linked NCBI taxonomy ID	48598
Linked level	genus

Family

Family in NCBI taxonomy	Corallinaceae
ID	31396

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Eukaryota
ID	2759

Plant class

Plant class
ID

Metabolite list (14)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001226	gamma-Linolenic acid / 6(Z),9(Z),12(Z)-Octadecatrienoic acid	CHEMBL464982	D017965	17 / 8 / 5	42 / 0	No. 300	No. 68
C00000423	5-HETE / 5-Hydroxyarachidonic acid	CHEMBL17695 CHEMBL164813		3 / 4 / 3		No. 300	No. 68
C00000424	12-HETE / 12-Hydroxyarachidonic acid	CHEMBL1435825 CHEMBL1526258		3 / 1 / 4		No. 300	No. 68
C00000425	11-HETE / 11-Hydroxyarachidonic acid	CHEMBL458854				No. 300	No. 68
C00000426	13-HAA / 13-Hydroxyarachidonic acid					No. 300	No. 68
C00000427	15-HETE / 15-Hydroxyarachidonic acid	CHEMBL594621		1 / 0 / 0		No. 300	No. 68
C00000435	(11R)-Hydroxy-6(Z),9(Z),12(Z)-octadecatrienoic acid		C078213			No. 300	No. 68
C00000433	5Z,8Z,10E,12E,14Z-Eicosapentaenoic acid					No. 300	No. 68
C00000429	11R-Hydroxy-9Z,12Z-octadecadienoic acid					No. 367	No. 68
C00000432	11-Keto-9Z,12Z-octadecadienoic acid					No. 367	No. 68
C00000430	9-HOD / 9-Hydroxy-10E,12Z-octadecadienoic acid	CHEMBL457771 CHEMBL1077284		1 / 5 / 3		No. 367	No. 68
C00000436	6Z,8E,10E,12Z-Octadecatetraenoic acid		C078215			No. 367	No. 68
C00000403	13-HOD / 13-Hydroxyoctadecadienoic acid / 13-Hydroxy-9Z,11E-octadecadienoic acid	CHEMBL451721 CHEMBL2069934		3 / 9 / 6		No. 367	No. 68
C00000428	(5Z,9E,11E,14E)-Ethyl 8-hydroxy-13-oxoicosa-5,9,11,14-tetraenoate					No. 7854

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000403 C00000430	5 / 3
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00000403 C00001226	2 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000424 C00001226	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000403 C00001226	2 / 3
O14880	Microsomal glutathione S-transferase 3	Enzyme	C00000423	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001226	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001226	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00001226	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00001226	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001226	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00001226	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001226	0 / 0
P49327	Fatty acid synthase	Transferase	C00001226	0 / 0
P13726	Tissue factor	Membrane receptor	C00001226	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001226	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000427	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000423	4 / 3
Q9UBT6	DNA polymerase kappa	Enzyme	C00001226	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000423	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00001226	1 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00000424	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00000424	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001226	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001226	2 / 1

42 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00001226
1109	AKR1C4, 3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA	aldo-keto reductase family 1, member C4 (EC:1.1.1.225 1.1.1.357)	C00001226
350	APOH, B2G1, B2GP1, BG	apolipoprotein H (beta-2-glycoprotein I)	C00001226
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00001226
427	ASAH1, AC, ACDase, ASAH, PHP, PHP32, SMAPME	N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23)	C00001226
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00001226
890	CCNA2, CCN1, CCNA	cyclin A2	C00001226
898	CCNE1, CCNE	cyclin E1	C00001226
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00001226
7122	CLDN5, AWAL, BEC1, CPETRL1, TMVCF	claudin 5	C00001226
1211	CLTA, LCA	clathrin, light chain A	C00001226
2495	FTH1, FHC, FTH, FTHL6, PIG15, PLIF	ferritin, heavy polypeptide 1 (EC:1.16.3.1)	C00001226
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00001226
2869	GRK5, GPRK5	G protein-coupled receptor kinase 5 (EC:2.7.11.16)	C00001226
3074	HEXB, ENC-1AS	hexosaminidase B (beta polypeptide) (EC:3.2.1.52)	C00001226
8334	HIST1H2AC, H2A/l, H2AFL, dJ221C16.4	histone cluster 1, H2ac	C00001226
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00001226
3558	IL2, IL-2, TCGF, lymphokine	interleukin 2	C00001226
3726	JUNB, AP-1	jun B proto-oncogene	C00001226
8942	KYNU	kynureninase (EC:3.7.1.3)	C00001226
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00001226
4320	MMP11, SL-3, ST3, STMY3	matrix metallopeptidase 11 (stromelysin 3) (EC:3.4.24.-)	C00001226
4495	MT1G, MT1, MT1K	metallothionein 1G	C00001226
4500	MT1L, MT1, MT1R, MTF	metallothionein 1L (gene/pseudogene)	C00001226
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00001226
100506658	OCLN, BLCPMG	occludin (EC:2.1.1.67)	C00001226
5111	PCNA	proliferating cell nuclear antigen	C00001226
9124	PDLIM1, CLIM1, CLP-36, CLP36, hCLIM1	PDZ and LIM domain 1	C00001226
123	PLIN2, ADFP, ADRP	perilipin 2	C00001226
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00001226
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00001226
22949	PTGR1, LTB4DH, PGR1, ZADH3	prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74)	C00001226
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001226
6286	S100P, MIG9	S100 calcium binding protein P	C00001226
6502	SKP2, FBL1, FBXL1, FLB1, p45	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	C00001226
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00001226
6767	ST13, AAG2, FAM10A1, FAM10A4, HIP, HOP, HSPABP, HSPABP1, P48, PRO0786, SNC6	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	C00001226
7033	TFF3, ITF, P1B, TFI	trefoil factor 3 (intestinal)	C00001226
7082	TJP1, ZO-1	tight junction protein 1	C00001226
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001226
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00001226
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00001226

Related Diseases

Diseases related to proteins in ChEMBL interactions