PCIDB

KNApSAcK Metabolite C00001342

Metabolite

KNApSAcK Entry

id C00001342
Name L-Aspartic acid
CAS RN 56-84-8
Standard InChI InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
Standard InChI (Main Layer) InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)

Cluster

Phytochemical cluster
KCF-S cluster No. 2641

Link

ChEMBL

By standard InChI CHEMBL274323
By standard InChI Main Layer CHEMBL274323 CHEMBL29757

KEGG

By LinkDB C00049

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Brassicaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae

Human Protein / Gene in interaction

19 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL274323 CHEMBL29757 CHEMBL1741321 (2)
1 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL274323 CHEMBL1614310 (1)
11 / 10
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL29757 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
P00918 Carbonic anhydrase 2 Lyase CHEMBL274323 CHEMBL657923 (1)
1 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL274323 CHEMBL29757 CHEMBL1741325 (2)
0 / 1
P54132 Bloom syndrome protein Enzyme CHEMBL274323 CHEMBL1614522 (1) CHEMBL1614067 (1)
1 / 2
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL274323 CHEMBL1614458 (2)
0 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL274323 CHEMBL662718 (1)
0 / 0
Q14416 Metabotropic glutamate receptor 2 Metabotropic glutamate receptor CHEMBL274323 CHEMBL29757 CHEMBL713617 (2)
0 / 0
O15303 Metabotropic glutamate receptor 6 Metabotropic glutamate receptor CHEMBL274323 CHEMBL29757 CHEMBL712215 (2)
1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL274323 CHEMBL29757 CHEMBL1741322 (2)
0 / 0
Q13255 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor CHEMBL274323 CHEMBL29757 CHEMBL717333 (2)
1 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL274323 CHEMBL29757 CHEMBL1613777 (1) CHEMBL1741323 (2)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL274323 CHEMBL29757 CHEMBL1741324 (2)
0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL274323 CHEMBL1614211 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL274323 CHEMBL1738442 (1)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL274323 CHEMBL1614364 (2)
1 / 1
O00255 Menin Unclassified protein CHEMBL274323 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL274323 CHEMBL1614257 (1)
1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (24)

OMIM preferred title UniProt
#210900 Bloom syndrome; blm P54132
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#257270 Night blindness, congenital stationary, type 1b; csnb1b O15303
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#275210 Restrictive dermopathy, lethal P02545
#614831 Spinocerebellar ataxia, autosomal recessive 13; scar13 Q13255
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8

KEGG DISEASE (28)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00787 Congenital stationary night blindness (CSNB) O15303 (related)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)