PCIDB

KNApSAcK Metabolite C00013562

Metabolite

KNApSAcK Entry

id C00013562
Name Amorphispironone / (1R,7'aR,10'aS)-10',10'a-Dihydro-4,5-dimethoxy-3',3'-dimethylspiro[3,5-cyclohexadiene-1,8'-[3H,8H]furo[3,4-e']benzo[1,2-b:3,4-b']dipyran]-2,7'(7'aH)-dione
CAS RN 139006-28-3
Standard InChI InChI=1S/C23H22O7/c1-22(2)8-7-12-14(30-22)6-5-13-20(25)19-17(29-21(12)13)11-28-23(19)10-16(27-4)15(26-3)9-18(23)24/h5-10,17,19H,11H2,1-4H3
Standard InChI (Main Layer) InChI=1S/C23H22O7/c1-22(2)8-7-12-14(30-22)6-5-13-20(25)19-17(29-21(12)13)11-28-23(19)10-16(27-4)15(26-3)9-18(23)24/h5-10,17,19H,11H2,1-4H3

Cluster

Phytochemical cluster
KCF-S cluster No. 7246

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL491001 CHEMBL1712104 CHEMBL1985734

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Fabaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Amorpha fruticosa 48131 Fabaceae rosids Viridiplantae

Human Protein / Gene in interaction

6 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL1712104 CHEMBL2114784 (1)
1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL1712104 CHEMBL1794585 (1)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL1712104 CHEMBL2114817 (1)
7 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL1712104 CHEMBL1738588 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1712104 CHEMBL1794483 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL1712104 CHEMBL1738184 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (4)

KEGG disease name UniProt
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)