PCIDB

KNApSAcK Metabolite C00001407

Metabolite

KNApSAcK Entry

id C00001407
Name N,N-Dimethyltryptamine
CAS RN 61-50-7
Standard InChI InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3
Standard InChI (Main Layer) InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 1385

Link

ChEMBL

By standard InChI CHEMBL12420
By standard InChI Main Layer CHEMBL12420

KEGG

By LinkDB C08302

CTD

By CAS RN D004130

Species

Summary

Plant class

class name count
rosids 17
asterids 2
Liliopsida 1
Embryophyta 1

Family

family name count
Fabaceae 16
Apocynaceae 1
Poaceae 1
Thorectidae 1
Rubiaceae 1
Rutaceae 1
Lycopodiaceae 1

List (22)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Acacia maidenii 795978 Fabaceae rosids Viridiplantae
Acacia oerfota 3808 Fabaceae rosids Viridiplantae
Acacia phlebophylla 866006 Fabaceae rosids Viridiplantae
Acacia polyacantha 875646 Fabaceae rosids Viridiplantae
Acacia rigidula 205076 Fabaceae rosids Viridiplantae
Acacia senegal 138043 Fabaceae rosids Viridiplantae
Acacia simplex 1387191 Fabaceae rosids Viridiplantae
Anadenanthera colubrina 148671 Fabaceae rosids Viridiplantae
Antirhea lucida 43446 Rubiaceae asterids Viridiplantae
Arundo donax 35708 Poaceae Liliopsida Viridiplantae
Codariocalyx motorius 1205713 Fabaceae rosids Viridiplantae
Evodia rutaecarpa 354523 Rutaceae rosids Viridiplantae
Lycopodium phlegmaria 41007 Lycopodiaceae Embryophyta Viridiplantae
Mimosa tenuiflora 138060 Fabaceae rosids Viridiplantae
Mimosa zimapanensis 21013 Fabaceae rosids Viridiplantae
Mucuna pruriens 157652 Fabaceae rosids Viridiplantae
Parapiptadenia excelsa 367334 Fabaceae rosids Viridiplantae
Petalostylis labicheoides 162878 Fabaceae rosids Viridiplantae
Piptadenia peregrina 148717 Fabaceae rosids Viridiplantae
Prestonia amazonica 52849 Apocynaceae asterids Viridiplantae
Pseudopiptadenia contorta 397646 Fabaceae rosids Viridiplantae
Smenospongia aurea 289409 Thorectidae Metazoa

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor CHEMBL12420 CHEMBL617410 (1)
0 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor CHEMBL12420 CHEMBL615729 (1)
0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor CHEMBL12420 CHEMBL617282 (1)
0 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor CHEMBL12420 CHEMBL993916 (1)
1 / 0

CTD interaction (3)

compound gene gene name gene description interaction interaction type form reference
pmid
D004130 3356 HTR2A
5-HT2A
HTR2
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled HTR2A gene SNP results in decreased susceptibility to N,N-Dimethyltryptamine decreases response to substance
gene 16314884
D004130 3356 HTR2A
5-HT2A
HTR2
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled HTR2A protein affects the susceptibility to N,N-Dimethyltryptamine affects response to substance
protein 16314884
D004130 3356 HTR2A
5-HT2A
HTR2
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled N,N-Dimethyltryptamine binds to and results in increased activity of HTR2A protein affects binding
/ increases activity
protein 16314884

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (1)

OMIM preferred title UniProt
#614674 Periodic fever, menstrual cycle-dependent P08908

Diseases related to CTD interactions

2 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D006212 D004130 Hallucinations marker/mechanism
9447860
D001523 D004130 Mental Disorders marker/mechanism
16342002