KNApSAcK Metabolite C00014615
Metabolite
KNApSAcK Entry
| id | C00014615 |
|---|---|
| Name | alpha,beta-Dihydroxanthohumol / 4,2',4'-Trihydroxy-6'-methoxy-3'-prenyldihydrochalcone |
| CAS RN | 102448-00-0 |
| Standard InChI | InChI=1S/C21H24O5/c1-13(2)4-10-16-18(24)12-19(26-3)20(21(16)25)17(23)11-7-14-5-8-15(22)9-6-14/h4-6,8-9,12,22,24-25H,7,10-11H2,1-3H3 |
| Standard InChI (Main Layer) | InChI=1S/C21H24O5/c1-13(2)4-10-16-18(24)12-19(26-3)20(21(16)25)17(23)11-7-14-5-8-15(22)9-6-14/h4-6,8-9,12,22,24-25H,7,10-11H2,1-3H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 1291 |
Link
ChEMBL
| By standard InChI | CHEMBL510279 |
|---|---|
| By standard InChI Main Layer | CHEMBL510279 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 1 |
Family
| family name | count |
|---|---|
| Cannabaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Humulus lupulus | 3486 | Cannabaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
14 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL510279 |
CHEMBL2114784
(1)
|
1 / 1 |
| Q96LD8 | Sentrin-specific protease 8 | Enzyme | CHEMBL510279 |
CHEMBL1738578
(1)
|
0 / 0 |
| P42574 | Caspase-3 | C14 | CHEMBL510279 |
CHEMBL1738414
(1)
|
0 / 0 |
| Q9BQF6 | Sentrin-specific protease 7 | Enzyme | CHEMBL510279 |
CHEMBL1738495
(1)
|
0 / 0 |
| Q9GZR1 | Sentrin-specific protease 6 | Enzyme | CHEMBL510279 |
CHEMBL1738502
(1)
|
0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL510279 |
CHEMBL1794584
(1)
|
2 / 0 |
| O75496 | Geminin | Unclassified protein | CHEMBL510279 |
CHEMBL2114843
(1)
CHEMBL2114780
(1)
|
0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | CHEMBL510279 |
CHEMBL1963933
(1)
|
1 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | CHEMBL510279 |
CHEMBL2114788
(1)
|
0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | CHEMBL510279 |
CHEMBL1737991
(1)
|
0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | CHEMBL510279 |
CHEMBL1614250
(1)
CHEMBL1614502
(1)
|
4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL510279 |
CHEMBL1738184
(1)
|
0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | CHEMBL510279 |
CHEMBL1963970
(1)
|
0 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | CHEMBL510279 |
CHEMBL1963970
(1)
|
0 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (8)
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #601665 | Obesity |
P32245
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|