PCIDB

KNApSAcK Metabolite C00001511

Metabolite

KNApSAcK Entry

id C00001511
Name Thymine
CAS RN 65-71-4
Standard InChI InChI=1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)
Standard InChI (Main Layer) InChI=1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)

Cluster

Phytochemical cluster
KCF-S cluster No. 3873

Link

ChEMBL

By standard InChI CHEMBL993
By standard InChI Main Layer CHEMBL993

KEGG

By LinkDB C00178

CTD

By CAS RN D013941

Human Protein / Gene in interaction

CTD interaction (7)

compound gene gene name gene description interaction interaction type form reference
pmid
D013941 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Thymine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 11103787
D013941 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased secretion of IL8 protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 11103787
D013941 4312 MMP1
CLG
CLGN
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 11103787
D013941 1890 TYMP
ECGF
ECGF1
MEDPS1
MNGIE
MTDPS1
PDECGF
TP
hPD-ECGF
thymidine phosphorylase (EC:2.4.2.4) Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased expression of MMP1 protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 11103787
D013941 1890 TYMP
ECGF
ECGF1
MEDPS1
MNGIE
MTDPS1
PDECGF
TP
hPD-ECGF
thymidine phosphorylase (EC:2.4.2.4) Thymine inhibits the reaction [[Thymidine co-treated with TYMP protein] results in increased secretion of IL8 protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 11103787
D013941 1890 TYMP
ECGF
ECGF1
MEDPS1
MNGIE
MTDPS1
PDECGF
TP
hPD-ECGF
thymidine phosphorylase (EC:2.4.2.4) Thymine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 11103787
D013941 1890 TYMP
ECGF
ECGF1
MEDPS1
MNGIE
MTDPS1
PDECGF
TP
hPD-ECGF
thymidine phosphorylase (EC:2.4.2.4) TYMP protein results in increased abundance of Thymine increases abundance
protein 11103787