Organism name | Phakellia mauritiana |
---|---|
Genus | Phakellia |
Family | Axinellidae |
Kingdom | Animalia |
Linked NCBI taxonomy name | Phakellia |
---|---|
Linked NCBI taxonomy ID | 85813 |
Linked level | genus |
Family in NCBI taxonomy | Axinellidae |
---|---|
ID | 45118 |
Kingdom (Superkingdom) in NCBI taxonomy | Metazoa |
---|---|
ID | 33208 |
Plant class | |
---|---|
ID |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00001511
![]() |
Thymine
|
CHEMBL993
|
D013941
|
4 / 0 | No. 3873 |
![]() |
||
C00028180
![]() |
Dibromophakellin
|
CHEMBL447696
CHEMBL609329 |
1 / 0 / 0 | No. 4018 |
![]() |
|||
C00028181
![]() |
Dibromophakellstatin
|
CHEMBL232462
CHEMBL390234 |
No. 4018 |
![]() |
||||
C00019697
![]() |
Deoxyuridine
/ 2'-Deoxyuridine |
CHEMBL353955
CHEMBL1256281 |
D003857
|
4 / 1 / 2 | No. 4547 |
![]() |
||
C00019698
![]() |
Thymidine
/ Deoxythymidine |
CHEMBL6497
CHEMBL42372 CHEMBL52609 CHEMBL211174 CHEMBL374731 CHEMBL2067985 |
D013936
|
6 / 4 / 3 | 16 / 16 | No. 4547 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P19971 | Thymidine phosphorylase | Enzyme | C00019697 C00019698 | 1 / 1 |
P04183 | Thymidine kinase, cytosolic | Enzyme | C00019697 C00019698 | 0 / 1 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00019698 | 3 / 1 |
O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00019698 | 0 / 0 |
P23919 | Thymidylate kinase | Enzyme | C00019698 | 0 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00019697 | 0 / 0 |
P30305 | M-phase inducer phosphatase 2 | Ser_Thr_Tyr | C00019697 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00019698 | 0 / 0 |
P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00028180 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
1890 | TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF | thymidine phosphorylase (EC:2.4.2.4) |
C00001511
C00019698
|
4312 | MMP1, CLG, CLGN | matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) |
C00001511
C00019698
|
3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00001511
C00019698
|
3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00001511
C00019698
|
1435 | CSF1, CSF-1, MCSF | colony stimulating factor 1 (macrophage) (EC:2.7.10.1) |
C00019698
|
1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00019698
|
356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) |
C00019698
|
3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00019698
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00019698
|
3479 | IGF1, IGF-I, IGF1A, IGFI | insulin-like growth factor 1 (somatomedin C) |
C00019698
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00019698
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00019698
|
4548 | MTR, HMAG, MS, cblG | 5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13) |
C00019698
|
4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00019698
|
9154 | SLC28A1, CNT1, HCNT1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
C00019698
|
248 | ALPI, IAP | alkaline phosphatase, intestinal (EC:3.1.3.1) |
C00019698
|
OMIM | preferred title | UniProt |
---|---|---|
#603041 | Mitochondrial dna depletion syndrome 1 (mngie type); mtdps1 |
P19971
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D058186 | Acute Kidney Injury |
C00019698
|
D001927 | Brain Diseases |
C00019698
|
D015179 | Colorectal Neoplasms |
C00019698
|
D003128 | COMA |
C00019698
|
D064420 | Drug-Related Side Effects and Adverse Reactions |
C00019698
|
D005076 | Exanthema |
C00019698
|
D007970 | Leukopenia |
C00019698
|
D008114 | Liver Neoplasms, Experimental |
C00019698
|
D052016 | Mucositis |
C00019698
|
D009336 | Necrosis |
C00019698
|
D009436 | Neural Tube Defects |
C00019698
|
D009461 | Neurologic Manifestations |
C00019698
|
D011297 | Prenatal Exposure Delayed Effects |
C00019698
|
D051437 | Renal Insufficiency |
C00019698
|
D013280 | Stomatitis |
C00019698
|
D013921 | Thrombocytopenia |
C00019698
|