Plant Species


Cumulative plant class count

class name count
Liliopsida 1

Cumulative family count

class name count
Axinellidae 2
Enterobacteriaceae 2
Orchidaceae 1
Subergorgiidae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00019697 External link 512 Deoxyuridine
/ 2'-Deoxyuridine
CHEMBL353955
CHEMBL1256281
D003857
4 / 1 / 2
C00019698 External link 512 Thymidine
/ Deoxythymidine
CHEMBL6497
CHEMBL42372
CHEMBL52609
CHEMBL211174
CHEMBL374731
CHEMBL2067985
D013936
6 / 4 / 3 16 / 16

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P19971 Thymidine phosphorylase Enzyme C00019697 C00019698 1 / 1
P04183 Thymidine kinase, cytosolic Enzyme C00019697 C00019698 0 / 1
P10828 Thyroid hormone receptor beta NR1A2 C00019698 3 / 1
O15245 Solute carrier family 22 member 1 Drug uniporter C00019698 0 / 0
P23919 Thymidylate kinase Enzyme C00019698 0 / 0
P06746 DNA polymerase beta Enzyme C00019697 0 / 0
P30305 M-phase inducer phosphatase 2 Ser_Thr_Tyr C00019697 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00019698 0 / 0

16 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
248 ALPI, IAP alkaline phosphatase, intestinal (EC:3.1.3.1) C00019698
581 BAX, BCL2L4 BCL2-associated X protein C00019698
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00019698
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00019698
1435 CSF1, CSF-1, MCSF colony stimulating factor 1 (macrophage) (EC:2.7.10.1) C00019698
1906 EDN1, ET1, HDLCQ7, PPET1 endothelin 1 C00019698
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00019698
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00019698
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00019698
3479 IGF1, IGF-I, IGF1A, IGFI insulin-like growth factor 1 (somatomedin C) C00019698
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00019698
4312 MMP1, CLG, CLGN matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) C00019698
4548 MTR, HMAG, MS, cblG 5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13) C00019698
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00019698
9154 SLC28A1, CNT1, HCNT1 solute carrier family 28 (concentrative nucleoside transporter), member 1 C00019698
1890 TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF thymidine phosphorylase (EC:2.4.2.4) C00019698

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#603041 Mitochondrial dna depletion syndrome 1 (mngie type); mtdps1 P19971
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (3)

KEGG name UniProt
H00005 Chronic lymphocytic leukemia (CLL) P04183 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00469 Mitochondrial DNA depletion syndrome (MDS) P19971 (related)

Diseases related to CTD interactions

16 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D058186 Acute Kidney Injury C00019698
D001927 Brain Diseases C00019698
D015179 Colorectal Neoplasms C00019698
D003128 COMA C00019698
D064420 Drug-Related Side Effects and Adverse Reactions C00019698
D005076 Exanthema C00019698
D007970 Leukopenia C00019698
D008114 Liver Neoplasms, Experimental C00019698
D052016 Mucositis C00019698
D009336 Necrosis C00019698
D009436 Neural Tube Defects C00019698
D009461 Neurologic Manifestations C00019698
D011297 Prenatal Exposure Delayed Effects C00019698
D051437 Renal Insufficiency C00019698
D013280 Stomatitis C00019698
D013921 Thrombocytopenia C00019698