| class name | count |
|---|---|
| Liliopsida | 1 |
| class name | count |
|---|---|
| Axinellidae | 2 |
| Enterobacteriaceae | 2 |
| Orchidaceae | 1 |
| Subergorgiidae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00019697
|
Deoxyuridine
/ 2'-Deoxyuridine |
CHEMBL353955
CHEMBL1256281 |
D003857
|
4 / 1 / 2 |
|
|
|
C00019698
|
Thymidine
/ Deoxythymidine |
CHEMBL6497
CHEMBL42372 CHEMBL52609 CHEMBL211174 CHEMBL374731 CHEMBL2067985 |
D013936
|
6 / 4 / 3 | 16 / 16 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P19971 | Thymidine phosphorylase | Enzyme | C00019697 C00019698 | 1 / 1 |
| P04183 | Thymidine kinase, cytosolic | Enzyme | C00019697 C00019698 | 0 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00019698 | 3 / 1 |
| O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00019698 | 0 / 0 |
| P23919 | Thymidylate kinase | Enzyme | C00019698 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00019697 | 0 / 0 |
| P30305 | M-phase inducer phosphatase 2 | Ser_Thr_Tyr | C00019697 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00019698 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 248 | ALPI, IAP | alkaline phosphatase, intestinal (EC:3.1.3.1) |
C00019698
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00019698
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00019698
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00019698
|
| 1435 | CSF1, CSF-1, MCSF | colony stimulating factor 1 (macrophage) (EC:2.7.10.1) |
C00019698
|
| 1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00019698
|
| 356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) |
C00019698
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00019698
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00019698
|
| 3479 | IGF1, IGF-I, IGF1A, IGFI | insulin-like growth factor 1 (somatomedin C) |
C00019698
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00019698
|
| 4312 | MMP1, CLG, CLGN | matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) |
C00019698
|
| 4548 | MTR, HMAG, MS, cblG | 5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13) |
C00019698
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00019698
|
| 9154 | SLC28A1, CNT1, HCNT1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
C00019698
|
| 1890 | TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF | thymidine phosphorylase (EC:2.4.2.4) |
C00019698
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #603041 | Mitochondrial dna depletion syndrome 1 (mngie type); mtdps1 |
P19971
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D058186 | Acute Kidney Injury |
C00019698
|
| D001927 | Brain Diseases |
C00019698
|
| D015179 | Colorectal Neoplasms |
C00019698
|
| D003128 | COMA |
C00019698
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00019698
|
| D005076 | Exanthema |
C00019698
|
| D007970 | Leukopenia |
C00019698
|
| D008114 | Liver Neoplasms, Experimental |
C00019698
|
| D052016 | Mucositis |
C00019698
|
| D009336 | Necrosis |
C00019698
|
| D009436 | Neural Tube Defects |
C00019698
|
| D009461 | Neurologic Manifestations |
C00019698
|
| D011297 | Prenatal Exposure Delayed Effects |
C00019698
|
| D051437 | Renal Insufficiency |
C00019698
|
| D013280 | Stomatitis |
C00019698
|
| D013921 | Thrombocytopenia |
C00019698
|