PCIDB

KNApSAcK Metabolite C00015437

Metabolite

KNApSAcK Entry

id C00015437
Name Amorfrutin A / 3-Hydroxy-4-isopentenyl-5-methoxybibenzyl-2-carboxylic acid
CAS RN 80489-90-3
Standard InChI InChI=1S/C21H24O4/c1-14(2)9-12-17-18(25-3)13-16(19(20(17)22)21(23)24)11-10-15-7-5-4-6-8-15/h4-9,13,22H,10-12H2,1-3H3,(H,23,24)
Standard InChI (Main Layer) InChI=1S/C21H24O4/c1-14(2)9-12-17-18(25-3)13-16(19(20(17)22)21(23)24)11-10-15-7-5-4-6-8-15/h4-9,13,22H,10-12H2,1-3H3,(H,23,24)

Cluster

Phytochemical cluster
KCF-S cluster No. 1953

Link

ChEMBL

By standard InChI CHEMBL491820
By standard InChI Main Layer CHEMBL491820

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

9 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 CHEMBL491820 CHEMBL2341921 (1)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL491820 CHEMBL1794486 (1)
0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL491820 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL491820 CHEMBL2114843 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL491820 CHEMBL2114788 (1)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL491820 CHEMBL2114817 (1)
7 / 3
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 CHEMBL491820 CHEMBL2341918 (1) CHEMBL2341919 (1)
CHEMBL2341920 (1)
5 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL491820 CHEMBL1738184 (1)
0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 CHEMBL491820 CHEMBL2341922 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#114500 Colorectal cancer; crc P84022
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#601665 Obesity P37231
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092

KEGG DISEASE (6)

KEGG disease name UniProt
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)