PCIDB

KNApSAcK Metabolite C00001570

Metabolite

KNApSAcK Entry

id C00001570
Name Jilkon / Lycoremin / Lycoremine / Galanthamine / (-)-Galanthamine
CAS RN 357-70-0
Standard InChI InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1
Standard InChI (Main Layer) InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 580

Link

ChEMBL

By standard InChI CHEMBL659
By standard InChI Main Layer CHEMBL659 CHEMBL492193 CHEMBL1565544 CHEMBL1623394 CHEMBL1624158

KEGG

By LinkDB C08526

CTD

By CAS RN D005702

Human Protein / Gene in interaction

104 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL659 CHEMBL492193 CHEMBL1565544 CHEMBL1614110 (3) CHEMBL1741321 (2)
CHEMBL1909136 (2)
1 / 0
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL659 CHEMBL1909139 (2)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL659 CHEMBL1909131 (2)
0 / 3
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) CHEMBL659 CHEMBL1909190 (2)
2 / 2
P08246 Neutrophil elastase S1A CHEMBL659 CHEMBL1909195 (2)
2 / 1
P33765 Adenosine receptor A3 Adenosine receptor CHEMBL659 CHEMBL1909215 (2)
0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 CHEMBL659 CHEMBL1909201 (2)
0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor CHEMBL659 CHEMBL1909176 (2)
0 / 0
P29466 Caspase-1 C14 CHEMBL659 CHEMBL1909193 (2)
0 / 0
P17252 Protein kinase C alpha type Alpha CHEMBL659 CHEMBL1909198 (2)
0 / 0
P27361 Mitogen-activated protein kinase 3 Erk CHEMBL659 CHEMBL1909199 (2)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL659 CHEMBL1909197 (2)
2 / 2
P02545 Prelamin-A/C Unclassified protein CHEMBL659 CHEMBL492193 CHEMBL1614544 (2)
11 / 10
P00918 Carbonic anhydrase 2 Lyase CHEMBL659 CHEMBL1909123 (2)
1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor CHEMBL659 CHEMBL1909092 (2)
0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase CHEMBL659 CHEMBL1909169 (2)
1 / 1
P25021 Histamine H2 receptor Histamine receptor CHEMBL659 CHEMBL1909157 (2)
0 / 0
P35367 Histamine H1 receptor Histamine receptor CHEMBL659 CHEMBL1909156 (2)
0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine CHEMBL659 CHEMBL1909143 (2)
1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor CHEMBL659 CHEMBL1909174 (2)
0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor CHEMBL659 CHEMBL1909090 (2)
0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor CHEMBL659 CHEMBL1909093 (2)
0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor CHEMBL659 CHEMBL1909127 (2)
0 / 0
P06241 Tyrosine-protein kinase Fyn Src CHEMBL659 CHEMBL1909204 (2)
0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr CHEMBL659 CHEMBL1909202 (2)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL659 CHEMBL492193 CHEMBL1565544 CHEMBL1614027 (1) CHEMBL1741325 (2)
CHEMBL1909135 (2)
0 / 1
Q13224 Glutamate receptor ionotropic, NMDA 2B NS CHEMBL659 CHEMBL1105655 (1) CHEMBL1105656 (1)
1 / 0
Q05586 Glutamate receptor ionotropic, NMDA 1 NS CHEMBL659 CHEMBL1105653 (1) CHEMBL1105654 (1)
CHEMBL1105655 (1) CHEMBL1105656 (1)
1 / 0
Q12879 Glutamate receptor ionotropic, NMDA 2A NS CHEMBL659 CHEMBL1105653 (1) CHEMBL1105654 (1)
0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL659 CHEMBL1909203 (2)
1 / 11
P11473 Vitamin D3 receptor NR1I1 CHEMBL659 CHEMBL1794311 (1)
2 / 3
P14416 D(2) dopamine receptor Dopamine receptor CHEMBL659 CHEMBL1909140 (2)
2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL659 CHEMBL1909130 (2)
0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor CHEMBL659 CHEMBL1909120 (2)
0 / 0
P41145 Kappa-type opioid receptor Opioid receptor CHEMBL659 CHEMBL1909181 (2)
0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor CHEMBL659 CHEMBL1909164 (2)
0 / 0
P29274 Adenosine receptor A2a Adenosine receptor CHEMBL659 CHEMBL1909214 (2)
0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor CHEMBL659 CHEMBL1909175 (2)
0 / 0
P05067 Amyloid beta A4 protein Membrane receptor CHEMBL659 CHEMBL948467 (1)
2 / 2
P50052 Type-2 angiotensin II receptor Angiotensin receptor CHEMBL659 CHEMBL1909096 (2)
1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr CHEMBL659 CHEMBL1909118 (2)
0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor CHEMBL659 CHEMBL1909166 (2)
1 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL659 CHEMBL1614458 (1)
0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 CHEMBL659 CHEMBL1909133 (2)
0 / 0
Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 CMGC dual-specificity kinase DYRK2 CHEMBL659 CHEMBL2182309 (1)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL1623394 CHEMBL1738606 (1)
0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase CHEMBL659 CHEMBL1909158 (2)
0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor CHEMBL659 CHEMBL1909088 (2)
0 / 0
P21917 D(4) dopamine receptor Dopamine receptor CHEMBL659 CHEMBL1909142 (2)
0 / 0
P30988 Calcitonin receptor Calcitonin receptor CHEMBL659 CHEMBL1909101 (2)
0 / 0
P35462 D(3) dopamine receptor Dopamine receptor CHEMBL659 CHEMBL1909141 (2)
1 / 0
P41143 Delta-type opioid receptor Opioid receptor CHEMBL659 CHEMBL1909180 (2)
0 / 0
Q92731 Estrogen receptor beta NR3A2 CHEMBL659 CHEMBL1909146 (2)
0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor CHEMBL659 CHEMBL1909104 (2)
0 / 0
P25101 Endothelin-1 receptor Endothelin receptor CHEMBL659 CHEMBL1909144 (2)
0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor CHEMBL659 CHEMBL1909100 (2)
0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor CHEMBL659 CHEMBL1909167 (2)
1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor CHEMBL659 CHEMBL1909129 (2)
0 / 0
P08311 Cathepsin G S1A CHEMBL659 CHEMBL1909194 (2)
0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor CHEMBL659 CHEMBL1909110 (2)
1 / 0
P03956 Interstitial collagenase M10A CHEMBL659 CHEMBL1909196 (2)
0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor CHEMBL659 CHEMBL1909119 (2)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL659 CHEMBL1909150 (2)
0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor CHEMBL659 CHEMBL1909171 (2)
2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor CHEMBL659 CHEMBL1909170 (2)
0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor CHEMBL659 CHEMBL1909122 (2)
0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin CHEMBL659 CHEMBL1909109 (2)
2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily CHEMBL659 CHEMBL1909205 (2)
5 / 10
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor CHEMBL659 CHEMBL1909172 (2)
1 / 0
P21452 Substance-K receptor Neurokinin receptor CHEMBL659 CHEMBL1909114 (2)
0 / 0
P06276 Cholinesterase Hydrolase CHEMBL659 CHEMBL654402 (1) CHEMBL654405 (1)
CHEMBL656091 (1) CHEMBL841224 (1)
CHEMBL829512 (1) CHEMBL861175 (1)
CHEMBL859943 (1) CHEMBL911303 (2)
CHEMBL895408 (1) CHEMBL900442 (1)
CHEMBL948465 (1) CHEMBL998780 (1)
CHEMBL978159 (1) CHEMBL965670 (1)
CHEMBL1054621 (1) CHEMBL1771987 (1)
CHEMBL2162063 (1) CHEMBL2319649 (1)
0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor CHEMBL659 CHEMBL1909125 (2)
0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor CHEMBL659 CHEMBL1909126 (2)
3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor CHEMBL659 CHEMBL1909108 (2)
0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor CHEMBL659 CHEMBL1909124 (2)
1 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL659 CHEMBL1909200 (2)
0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme CHEMBL659 CHEMBL1909207 (2)
2 / 1
P56817 Beta-secretase 1 A1A CHEMBL659 CHEMBL2050827 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL659 CHEMBL492193 CHEMBL1565544 CHEMBL1741322 (2) CHEMBL1909132 (2)
0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A CHEMBL659 CHEMBL1909186 (2)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL659 CHEMBL1909145 (2)
1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor CHEMBL659 CHEMBL1909091 (2)
1 / 0
P22303 Acetylcholinesterase Hydrolase CHEMBL659 CHEMBL644110 (1) CHEMBL644119 (1)
CHEMBL644832 (1) CHEMBL684541 (1)
CHEMBL841224 (1) CHEMBL874440 (1)
CHEMBL859798 (1) CHEMBL859943 (1)
CHEMBL866863 (1) CHEMBL911302 (2)
CHEMBL919956 (1) CHEMBL895407 (1)
CHEMBL895409 (1) CHEMBL925438 (1)
CHEMBL965187 (1) CHEMBL948464 (1)
CHEMBL948466 (1) CHEMBL998779 (1)
CHEMBL978158 (1) CHEMBL979444 (1)
CHEMBL975663 (1) CHEMBL975665 (1)
CHEMBL974116 (1) CHEMBL974073 (1)
CHEMBL965669 (1) CHEMBL1054620 (1)
CHEMBL1042165 (1) CHEMBL1047004 (1)
CHEMBL1119101 (1) CHEMBL1227597 (1)
CHEMBL1648270 (2) CHEMBL1663835 (1)
CHEMBL1671288 (1) CHEMBL1771986 (1)
CHEMBL1787066 (1) CHEMBL1787067 (1)
CHEMBL1787068 (1) CHEMBL1787069 (1)
CHEMBL1809351 (1) CHEMBL1909212 (2)
CHEMBL2020014 (1) CHEMBL2050824 (1)
CHEMBL2050829 (1) CHEMBL2072352 (1)
CHEMBL2162062 (1) CHEMBL2319650 (1)
CHEMBL2345676 (1)
1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor CHEMBL659 CHEMBL1909211 (2)
0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor CHEMBL659 CHEMBL1909105 (2)
0 / 0
P35372 Mu-type opioid receptor Opioid receptor CHEMBL659 CHEMBL1909182 (2)
0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor CHEMBL659 CHEMBL1909173 (2)
0 / 0
P25103 Substance-P receptor Neurokinin receptor CHEMBL659 CHEMBL1909113 (2)
0 / 0
P25105 Platelet-activating factor receptor PAF receptor CHEMBL659 CHEMBL1909187 (2)
0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor CHEMBL659 CHEMBL1909168 (2)
0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme CHEMBL492193 CHEMBL1614240 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL659 CHEMBL492193 CHEMBL1565544 CHEMBL1613777 (1) CHEMBL1741323 (2)
CHEMBL1909134 (2)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL659 CHEMBL492193 CHEMBL1565544 CHEMBL1029448 (1) CHEMBL1741324 (2)
CHEMBL1909138 (2)
0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 CHEMBL659 CHEMBL1909137 (2)
0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine CHEMBL659 CHEMBL1909094 (2)
1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor CHEMBL659 CHEMBL1909087 (2)
0 / 0
P30542 Adenosine receptor A1 Adenosine receptor CHEMBL659 CHEMBL1909213 (2)
0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor CHEMBL659 CHEMBL1909089 (2)
0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 CHEMBL659 CHEMBL1909116 (2)
1 / 1
P06239 Tyrosine-protein kinase Lck Src CHEMBL659 CHEMBL1909206 (2)
0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor CHEMBL659 CHEMBL1909128 (2)
0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 CHEMBL659 CHEMBL2182310 (1)
1 / 0
O00255 Menin Unclassified protein CHEMBL492193 CHEMBL1614531 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL492193 CHEMBL1614531 (1)
1 / 3

CTD interaction (5)

compound gene gene name gene description interaction interaction type form reference
pmid
D005702 43 ACHE
ACEE
ARACHE
N-ACHE
YT
acetylcholinesterase (EC:3.1.1.7) Galantamine results in decreased activity of ACHE protein decreases activity
protein 14535624
18573242
D005702 1137 CHRNA4
BFNC
EBN
EBN1
NACHR
NACHRA4
NACRA4
cholinergic receptor, nicotinic, alpha 4 (neuronal) Galantamine binds to [CHRNA4 protein binds to CHRNB2 protein] affects binding
protein 15733544
D005702 1137 CHRNA4
BFNC
EBN
EBN1
NACHR
NACHRA4
NACRA4
cholinergic receptor, nicotinic, alpha 4 (neuronal) Galantamine inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] affects activity
/ affects binding
/ decreases reaction
protein 15733544
D005702 1141 CHRNB2
EFNL3
nAChRB2
cholinergic receptor, nicotinic, beta 2 (neuronal) Galantamine binds to [CHRNA4 protein binds to CHRNB2 protein] affects binding
protein 15733544
D005702 1141 CHRNB2
EFNL3
nAChRB2
cholinergic receptor, nicotinic, beta 2 (neuronal) Galantamine inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] affects activity
/ affects binding
/ decreases reaction
protein 15733544

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (57)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
P14416
P31645
#104300 Alzheimer disease; ad P05067
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605714 Cerebral amyloid angiopathy, app-related P05067
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#615363 Estrogen resistance; estrr P03372
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 P04626
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603932 Intervertebral disc disease; idd P14780
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613970 Mental retardation, autosomal dominant 6; mrd6 Q13224
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#614254 Mental retardation, autosomal dominant 8; mrd8 Q05586
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#190300 Tremor, hereditary essential, 1; etm1 P35462
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303

KEGG DISEASE (53)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00056 Alzheimer's disease (AD) P05067 (related)
H01185 Cerebral amyloid angiopathy (CAA) P05067 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00025 Penile cancer P14780 (related)
P35354 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00548 Brunner syndrome P21397 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)

Diseases related to CTD interactions

25 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D000544 D005702 Alzheimer Disease therapeutic
12220392
16274397
16914529
17414243
17926835
18506913
D000647 D005702 Amnesia therapeutic
1738791
17152362
D054537 D005702 Atrioventricular Block marker/mechanism
16566422
19008069
D001321 D005702 Autistic Disorder therapeutic
17069550
D001919 D005702 Bradycardia marker/mechanism
16566422
19008069
D003072 D005702 Cognition Disorders marker/mechanism
therapeutic
15630600
20184916
D003693 D005702 Delirium marker/mechanism
18182475
D015140 D005702 Dementia, Vascular therapeutic
12220392
D003967 D005702 Diarrhea marker/mechanism
18182475
D062787 D005702 Drug Overdose therapeutic
603022
D004421 D005702 Dystonia marker/mechanism
15389998
18506913
D006261 D005702 Headache marker/mechanism
17069550
D006948 D005702 Hyperkinesis therapeutic
12721372
D007022 D005702 Hypotension marker/mechanism
18182475
D007859 D005702 Learning Disorders therapeutic
17851187
D008133 D005702 Long QT Syndrome marker/mechanism
16426108
18182475
D020258 D005702 Neurotoxicity Syndromes marker/mechanism
19782102
D010243 D005702 Paralysis therapeutic
19647007
D010259 D005702 Paranoid Disorders marker/mechanism
16274397
D011041 D005702 Poisoning therapeutic
16914529
D049188 D005702 Prenatal Injuries marker/mechanism
14657522
D012640 D005702 Seizures therapeutic
19647007
D013575 D005702 Syncope marker/mechanism
18182475
D014202 D005702 Tremor marker/mechanism
8205054
D014839 D005702 Vomiting marker/mechanism
18182475
19669943