KNApSAcK Metabolite C00001579
Metabolite
KNApSAcK Entry
| id | C00001579 |
|---|---|
| Name | Pancratistatin / (+)-Pancratistatin |
| CAS RN | 96203-70-2 |
| Standard InChI | InChI=1S/C14H15NO8/c16-8-5-3-1-4-13(23-2-22-4)9(17)6(3)14(21)15-7(5)10(18)12(20)11(8)19/h1,5,7-8,10-12,16-20H,2H2,(H,15,21)/t5-,7-,8-,10+,11+,12+/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C14H15NO8/c16-8-5-3-1-4-13(23-2-22-4)9(17)6(3)14(21)15-7(5)10(18)12(20)11(8)19/h1,5,7-8,10-12,16-20H,2H2,(H,15,21) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 4012 |
Link
ChEMBL
| By standard InChI | CHEMBL419335 |
|---|---|
| By standard InChI Main Layer | CHEMBL419335 CHEMBL223299 CHEMBL1736766 CHEMBL2036086 |
KEGG
| By LinkDB | C08535 |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| Liliopsida | 8 |
| eudicotyledons | 1 |
Family
| family name | count |
|---|---|
| Amaryllidaceae | 8 |
| Ranunculaceae | 1 |
List (10)
* NCBI
Human Protein / Gene in interaction
9 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL1736766 |
CHEMBL2114784
(1)
|
1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL1736766 |
CHEMBL1794584
(1)
|
2 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | CHEMBL1736766 |
CHEMBL2114788
(1)
|
0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | CHEMBL1736766 |
CHEMBL2114810
(1)
|
7 / 3 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL419335 |
CHEMBL1029448
(1)
|
0 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL1736766 |
CHEMBL1738184
(1)
|
0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | CHEMBL1736766 |
CHEMBL2354311
(1)
|
1 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | CHEMBL1736766 |
CHEMBL2114913
(1)
|
0 / 3 |
| Q06710 | Paired box protein Pax-8 | Unclassified protein | CHEMBL1736766 |
CHEMBL2354301
(1)
|
1 / 2 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (12)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
KEGG DISEASE (9)
| KEGG | disease name | UniProt |
|---|---|---|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
Q06710 (related) |
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00032 | Thyroid cancer |
Q06710
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|