Brachystola magna
Metabolite list (2)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001579
|
Pancratistatin
/ (+)-Pancratistatin |
CHEMBL419335
CHEMBL223299 CHEMBL1736766 CHEMBL2036086 |
9 / 12 / 9 | No. 4012 |
|
|||
|
C00001577
|
Narciclasine
/ Lycoricidinol |
CHEMBL98745
CHEMBL367376 |
C010753
|
9 / 17 / 9 | No. 4581 |
|
Human Protein / Gene in interactions
13 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00001577 C00001579 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001577 C00001579 | 1 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001577 C00001579 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001577 C00001579 | 0 / 1 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00001577 C00001579 | 7 / 3 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00001579 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00001577 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00001579 | 2 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00001577 | 2 / 2 |
| P37840 | Alpha-synuclein | Unclassified protein | C00001577 | 4 / 2 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001577 | 2 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00001579 | 0 / 3 |
| Q06710 | Paired box protein Pax-8 | Unclassified protein | C00001579 | 1 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (20)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
KEGG DISEASE (13)
| KEGG | name | UniProt |
|---|---|---|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
Q06710 (related) |
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00032 | Thyroid cancer |
Q06710
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|