PCIDB

KCF-S cluster No. 4581 (2 metabolites)

Plant Species

Cumulative plant class count

class name count
Liliopsida 6

Cumulative family count

class name count
Amaryllidaceae 6

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00001575 External link 512 Lycoricidine
CHEMBL487798
CHEMBL1728514
9 / 6 / 4
C00001577 External link 512 Narciclasine
/ Lycoricidinol
CHEMBL98745
CHEMBL367376
C010753
9 / 17 / 9

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00001575 C00001577 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001575 C00001577 1 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001575 C00001577 0 / 0
O75496 Geminin Unclassified protein C00001575 C00001577 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00001577 7 / 3
P17405 Sphingomyelin phosphodiesterase Enzyme C00001577 2 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00001575 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001575 2 / 0
Q9Y253 DNA polymerase eta Enzyme C00001575 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001577 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00001575 0 / 0
P37840 Alpha-synuclein Unclassified protein C00001577 4 / 2
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001577 2 / 0
Q06710 Paired box protein Pax-8 Unclassified protein C00001575 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (21)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#137800 Glioma susceptibility 1; glm1 O75874
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (12)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00032 Thyroid cancer Q06710 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) Q06710 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)