PCIDB

KNApSAcK Metabolite C00016002

Metabolite

KNApSAcK Entry

id C00016002
Name TSA / Trichostatin A / (R)-Trichostatin A
CAS RN 58880-19-6
Standard InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
Standard InChI (Main Layer) InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)

Cluster

Phytochemical cluster
KCF-S cluster No. 5192

Link

ChEMBL

By standard InChI CHEMBL99
By standard InChI Main Layer CHEMBL99 CHEMBL26159

KEGG

By LinkDB

CTD

By CAS RN C012589

Species

Summary

Plant class

class name count

Family

family name count
Bacillaceae 1
Streptomycetaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Bacillus megaterium 6N38 186817 Bacillaceae Bacteria
Streptomyces hygroscopicus 1912 Streptomycetaceae Bacteria

Human Protein / Gene in interaction

25 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P13569 Cystic fibrosis transmembrane conductance regulator chloride CHEMBL99 CHEMBL1267913 (1)
2 / 3
Q16637 Survival motor neuron protein Unclassified protein CHEMBL99 CHEMBL1614260 (1) CHEMBL1613842 (1)
4 / 2
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL99 CHEMBL1794499 (1)
2 / 0
P04062 Glucosylceramidase Enzyme CHEMBL99 CHEMBL1613818 (1)
6 / 4
Q96DB2 Histone deacetylase 11 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL695137 (1) CHEMBL695138 (1)
CHEMBL695139 (1) CHEMBL695142 (1)
CHEMBL697246 (1) CHEMBL697247 (2)
CHEMBL831536 (1) CHEMBL830654 (1)
CHEMBL960041 (1) CHEMBL1634310 (1)
CHEMBL1921146 (1) CHEMBL2318992 (1)
0 / 0
Q13547 Histone deacetylase 1 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL694194 (1) CHEMBL695137 (1)
CHEMBL695138 (1) CHEMBL695139 (1)
CHEMBL695142 (1) CHEMBL697246 (1)
CHEMBL697247 (2) CHEMBL701991 (1)
CHEMBL701992 (1) CHEMBL877713 (1)
CHEMBL701996 (1) CHEMBL697291 (1)
CHEMBL810946 (1) CHEMBL827901 (1)
CHEMBL831536 (1) CHEMBL830654 (1)
CHEMBL881892 (1) CHEMBL868653 (1)
CHEMBL908252 (1) CHEMBL899908 (1)
CHEMBL924050 (1) CHEMBL925324 (1)
CHEMBL926150 (1) CHEMBL922259 (1)
CHEMBL921442 (1) CHEMBL976441 (1)
CHEMBL954935 (1) CHEMBL960031 (1)
CHEMBL1032117 (1) CHEMBL1049814 (1)
CHEMBL1073571 (1) CHEMBL1101056 (1)
CHEMBL1166728 (1) CHEMBL1166309 (1)
CHEMBL1167402 (1) CHEMBL1216982 (1)
CHEMBL1267846 (1) CHEMBL1293050 (1)
CHEMBL1634190 (1) CHEMBL1670515 (1)
CHEMBL1816686 (1) CHEMBL1838366 (1)
CHEMBL1921154 (1) CHEMBL1959442 (1)
CHEMBL2014066 (1) CHEMBL2024762 (1)
CHEMBL2050436 (1) CHEMBL2089598 (1)
CHEMBL2160543 (1) CHEMBL2188465 (1)
CHEMBL2318998 (1)
0 / 0
Q9BY41 Histone deacetylase 8 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL695137 (1) CHEMBL695138 (1)
CHEMBL695139 (1) CHEMBL695142 (1)
CHEMBL697246 (1) CHEMBL697247 (2)
CHEMBL827903 (1) CHEMBL831536 (1)
CHEMBL830654 (1) CHEMBL976444 (1)
CHEMBL991292 (1) CHEMBL954938 (1)
CHEMBL960038 (1) CHEMBL1049816 (1)
CHEMBL1101059 (1) CHEMBL1166732 (1)
CHEMBL1166313 (1) CHEMBL1216989 (1)
CHEMBL1267839 (1) CHEMBL1634303 (1)
CHEMBL1670520 (1) CHEMBL1816689 (1)
CHEMBL2175141 (1) CHEMBL2318993 (1)
2 / 0
P11473 Vitamin D3 receptor NR1I1 CHEMBL99 CHEMBL1794311 (1)
2 / 3
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL99 CHEMBL1614458 (1)
0 / 0
Q92769 Histone deacetylase 2 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL695137 (1) CHEMBL695138 (1)
CHEMBL695139 (1) CHEMBL695142 (1)
CHEMBL697246 (1) CHEMBL697247 (2)
CHEMBL831536 (1) CHEMBL830654 (1)
CHEMBL881893 (1) CHEMBL976442 (1)
CHEMBL991290 (1) CHEMBL954936 (1)
CHEMBL960032 (1) CHEMBL1101057 (1)
CHEMBL1166729 (1) CHEMBL1166310 (1)
CHEMBL1216983 (1) CHEMBL1267844 (1)
CHEMBL1634301 (1) CHEMBL1670516 (1)
CHEMBL1816687 (1) CHEMBL1921153 (1)
CHEMBL1959441 (1) CHEMBL2024763 (1)
CHEMBL2318997 (1)
0 / 0
Q9UQL6 Histone deacetylase 5 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL695137 (1) CHEMBL695138 (1)
CHEMBL695139 (1) CHEMBL695142 (1)
CHEMBL697246 (1) CHEMBL697247 (2)
CHEMBL831536 (1) CHEMBL830654 (1)
CHEMBL960035 (1) CHEMBL1216986 (1)
CHEMBL1267841 (1) CHEMBL1634305 (1)
CHEMBL1921151 (1) CHEMBL2318995 (1)
0 / 0
Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 Enzyme CHEMBL99 CHEMBL909832 (1) CHEMBL1049696 (1)
0 / 0
Q15393 Splicing factor 3B subunit 3 Unclassified protein CHEMBL99 CHEMBL1243662 (1) CHEMBL1243663 (1)
CHEMBL1243677 (1) CHEMBL1243914 (1)
0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein CHEMBL99 CHEMBL1963893 (2)
0 / 0
Q969S8 Histone deacetylase 10 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL695137 (1) CHEMBL695138 (1)
CHEMBL695139 (1) CHEMBL695142 (1)
CHEMBL697246 (1) CHEMBL697247 (2)
CHEMBL831536 (1) CHEMBL830654 (1)
CHEMBL976446 (1) CHEMBL954939 (1)
CHEMBL960040 (1) CHEMBL1101060 (1)
CHEMBL1166735 (1) CHEMBL1267838 (1)
CHEMBL1634309 (1) CHEMBL1921147 (1)
0 / 0
P13726 Tissue factor Membrane receptor CHEMBL99 CHEMBL1004857 (1) CHEMBL1004858 (1)
CHEMBL1004859 (1) CHEMBL1004860 (1)
CHEMBL1004861 (1) CHEMBL986955 (1)
CHEMBL986967 (1) CHEMBL986968 (1)
0 / 0
O15379 Histone deacetylase 3 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL695137 (1) CHEMBL695138 (1)
CHEMBL695139 (1) CHEMBL695142 (1)
CHEMBL697246 (1) CHEMBL697247 (2)
CHEMBL831536 (1) CHEMBL830654 (1)
CHEMBL929248 (2) CHEMBL976443 (1)
CHEMBL954937 (1) CHEMBL960033 (1)
CHEMBL1049815 (1) CHEMBL1101058 (1)
CHEMBL1166730 (1) CHEMBL1166311 (1)
CHEMBL1216984 (1) CHEMBL1267845 (1)
CHEMBL1634302 (1) CHEMBL1670517 (1)
0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL99 CHEMBL2114827 (1) CHEMBL2114907 (1)
CHEMBL2114929 (1)
0 / 0
P56524 Histone deacetylase 4 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL695137 (1) CHEMBL695138 (1)
CHEMBL695139 (1) CHEMBL695142 (1)
CHEMBL697246 (1) CHEMBL697247 (2)
CHEMBL811365 (2) CHEMBL827902 (1)
CHEMBL831536 (1) CHEMBL830654 (1)
CHEMBL868654 (1) CHEMBL898810 (1)
CHEMBL924051 (1) CHEMBL925325 (1)
CHEMBL926151 (1) CHEMBL921443 (1)
CHEMBL960034 (1) CHEMBL1073572 (1)
CHEMBL1073575 (1) CHEMBL1216985 (1)
CHEMBL1267843 (1) CHEMBL1634304 (1)
CHEMBL1670518 (1) CHEMBL1921152 (1)
CHEMBL2160545 (1) CHEMBL2318996 (1)
1 / 1
Q8WUI4 Histone deacetylase 7 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL695137 (1) CHEMBL695138 (1)
CHEMBL695139 (1) CHEMBL695142 (1)
CHEMBL697246 (1) CHEMBL697247 (2)
CHEMBL831536 (1) CHEMBL830654 (1)
CHEMBL960037 (1) CHEMBL1216988 (1)
CHEMBL1267277 (1) CHEMBL1267840 (1)
CHEMBL1267851 (1) CHEMBL1267908 (1)
CHEMBL1634306 (1) CHEMBL1921149 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL99 CHEMBL1614421 (1)
4 / 3
Q9UBN7 Histone deacetylase 6 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL695137 (1) CHEMBL695138 (1)
CHEMBL695139 (1) CHEMBL695142 (1)
CHEMBL697246 (1) CHEMBL697247 (2)
CHEMBL877320 (1) CHEMBL831536 (1)
CHEMBL830654 (1) CHEMBL881895 (1)
CHEMBL868655 (1) CHEMBL924052 (1)
CHEMBL926152 (1) CHEMBL921172 (1)
CHEMBL921444 (1) CHEMBL929249 (2)
CHEMBL976445 (1) CHEMBL991291 (1)
CHEMBL954940 (1) CHEMBL960036 (1)
CHEMBL1049817 (1) CHEMBL1073573 (1)
CHEMBL1101061 (1) CHEMBL1166731 (1)
CHEMBL1166312 (1) CHEMBL1216987 (1)
CHEMBL1267842 (1) CHEMBL1293051 (1)
CHEMBL1634308 (1) CHEMBL1670519 (1)
CHEMBL1816688 (1) CHEMBL1921150 (1)
CHEMBL2050442 (1) CHEMBL2160547 (1)
CHEMBL2188464 (1) CHEMBL2318994 (1)
0 / 0
Q9UKV0 Histone deacetylase 9 Hydrolase CHEMBL99 CHEMBL686829 (1) CHEMBL694956 (1)
CHEMBL694958 (1) CHEMBL694905 (1)
CHEMBL695137 (1) CHEMBL695138 (1)
CHEMBL695139 (1) CHEMBL695142 (1)
CHEMBL697246 (1) CHEMBL697247 (2)
CHEMBL831536 (1) CHEMBL830654 (1)
CHEMBL960039 (1) CHEMBL1216990 (1)
CHEMBL1267837 (1) CHEMBL1634307 (1)
CHEMBL1921148 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL99 CHEMBL1738442 (1)
0 / 0
Q9Y618 Nuclear receptor corepressor 2 Unclassified protein CHEMBL99 CHEMBL929248 (2)
0 / 0

CTD interaction (766)

compound gene gene name gene description interaction interaction type form reference
pmid
C012589 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) [[decitabine co-treated with trichostatin A] affects the methylation of ABCB1 gene] which affects the expression of ABCB1 mRNA affects cotreatment
/ affects expression
/ affects methylation
gene / mRNA 18673531
C012589 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) [trichostatin A affects the methylation of ABCB1 gene] which affects the expression of ABCB1 mRNA affects expression
/ affects methylation
gene / mRNA 18673531
C012589 89845 ABCC10
EST182763
MRP7
SIMRP7
ATP-binding cassette, sub-family C (CFTR/MRP), member 10 trichostatin A results in increased expression of ABCC10 mRNA increases expression
mRNA 12566991
C012589 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 trichostatin A results in decreased expression of ABCC2 mRNA decreases expression
mRNA 10691972
C012589 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 trichostatin A results in decreased expression of ABCC2 protein decreases expression
protein 10691972
C012589 8714 ABCC3
ABC31
EST90757
MLP2
MOAT-D
MRP3
cMOAT2
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 trichostatin A results in decreased expression of ABCC3 mRNA decreases expression
mRNA 10691972
C012589 25 ABL1
ABL
JTK7
bcr/abl
c-ABL
p150
v-abl
c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) trichostatin A results in decreased expression of ABL1 mRNA decreases expression
mRNA 19606018
C012589 132 ADK
AK
adenosine kinase (EC:2.7.1.20) trichostatin A inhibits the reaction [Nickel affects the expression of ADK mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 196 AHR
bHLHe76
aryl hydrocarbon receptor trichostatin A results in increased expression of AHR mRNA increases expression
mRNA 12927368
C012589 9131 AIFM1
AIF
CMTX4
COWCK
COXPD6
PDCD8
apoptosis-inducing factor, mitochondrion-associated, 1 [perifosine co-treated with trichostatin A] results in increased secretion of AIFM1 protein affects cotreatment
/ increases secretion
protein 15781658
C012589 9131 AIFM1
AIF
CMTX4
COWCK
COXPD6
PDCD8
apoptosis-inducing factor, mitochondrion-associated, 1 [vorinostat co-treated with trichostatin A] affects the localization of AIFM1 protein affects cotreatment
/ affects localization
protein 16026644
C012589 9590 AKAP12
AKAP250
SSeCKS
A kinase (PRKA) anchor protein 12 [[decitabine co-treated with trichostatin A] affects the methylation of AKAP12 promoter] which affects the expression of AKAP12 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18803327
C012589 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) AKT1 protein modified form results in decreased activity of [perifosine co-treated with trichostatin A] affects cotreatment
/ decreases activity
protein 15781658
C012589 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) [perifosine co-treated with trichostatin A] results in decreased activity of AKT1 protein affects cotreatment
/ decreases activity
protein 15781658
C012589 51129 ANGPTL4
ANGPTL2
ARP4
FIAF
HARP
HFARP
NL2
PGAR
UNQ171
pp1158
angiopoietin-like 4 [decitabine co-treated with trichostatin A] results in increased expression of ANGPTL4 mRNA affects cotreatment
/ increases expression
mRNA 21489049
C012589 302 ANXA2
ANX2
ANX2L4
CAL1H
LIP2
LPC2
LPC2D
P36
PAP-IV
annexin A2 [trichostatin A co-treated with decitabine] results in increased expression of ANXA2 protein affects cotreatment
/ increases expression
protein 19294695
C012589 302 ANXA2
ANX2
ANX2L4
CAL1H
LIP2
LPC2
LPC2D
P36
PAP-IV
annexin A2 trichostatin A results in increased expression of ANXA2 protein increases expression
protein 19294695
C012589 317 APAF1
APAF-1
CED4
apoptotic peptidase activating factor 1 trichostatin A results in increased activity of APAF1 protein increases activity
protein 20925046
C012589 317 APAF1
APAF-1
CED4
apoptotic peptidase activating factor 1 [trichostatin A results in increased activity of APAF1 protein] which results in increased susceptibility to Cisplatin increases activity
/ increases response to substance
protein 20925046
C012589 328 APEX1
APE
APE1
APEN
APEX
APX
HAP1
REF1
APEX nuclease (multifunctional DNA repair enzyme) 1 (EC:4.2.99.18) trichostatin A promotes the reaction [EP300 protein binds to APEX1 protein] affects binding
/ increases reaction
protein 20856196
C012589 328 APEX1
APE
APE1
APEN
APEX
APX
HAP1
REF1
APEX nuclease (multifunctional DNA repair enzyme) 1 (EC:4.2.99.18) trichostatin A results in increased acetylation of APEX1 protein increases acetylation
protein 20856196
C012589 347 APOD
apolipoprotein D [decitabine co-treated with trichostatin A] affects the expression of APOD mRNA affects cotreatment
/ affects expression
mRNA 16865689
C012589 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trichostatin A results in decreased expression of AR protein] decreases expression
/ decreases reaction
protein 19805354
C012589 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor [trichostatin A co-treated with decitabine] results in increased expression of AR mRNA affects cotreatment
/ increases expression
mRNA 18092350
C012589 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor trichostatin A results in decreased expression of AR protein decreases expression
protein 19805354
C012589 10565 ARFGEF1
ARFGEP1
BIG1
P200
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) trichostatin A inhibits the reaction [Nickel affects the expression of ARFGEF1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 201176 ARHGAP27
CAMGAP1
PP905
SH3D20
SH3P20
Rho GTPase activating protein 27 [[decitabine co-treated with trichostatin A] affects the methylation of ARHGAP27 promoter] which affects the expression of ARHGAP27 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18803327
C012589 27237 ARHGEF16
GEF16
NBR
Rho guanine nucleotide exchange factor (GEF) 16 [[decitabine co-treated with trichostatin A] affects the methylation of ARHGEF16 promoter] which affects the expression of ARHGEF16 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18803327
C012589 11872 trichostatin A inhibits the reaction [Nickel affects the expression of ART2B mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 430 ASCL2
ASH2
HASH2
MASH2
bHLHa45
achaete-scute family bHLH transcription factor 2 trichostatin A inhibits the reaction [Nickel affects the expression of ASCL2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 51802 ASIC5
ACCN5
HINAC
INAC
acid-sensing (proton-gated) ion channel family member 5 trichostatin A inhibits the reaction [Nickel affects the expression of ASIC5 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 482 ATP1B2
AMOG
ATPase, Na+/K+ transporting, beta 2 polypeptide (EC:3.6.3.9) [decitabine co-treated with trichostatin A] affects the expression of ATP1B2 mRNA affects cotreatment
/ affects expression
mRNA 16865689
C012589 489 ATP2A3
SERCA3
ATPase, Ca++ transporting, ubiquitous (EC:3.6.3.8) trichostatin A inhibits the reaction [Nickel affects the expression of ATP2A3 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 506 ATP5B
ATPMB
ATPSB
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14) trichostatin A affects the expression of ATP5B protein affects expression
protein 19294695
C012589 506 ATP5B
ATPMB
ATPSB
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14) [trichostatin A co-treated with decitabine] results in increased expression of ATP5B protein affects cotreatment
/ increases expression
protein 19294695
C012589 6790 AURKA
AIK
ARK1
AURA
AURORA2
BTAK
PPP1R47
STK15
STK6
STK7
aurora kinase A (EC:2.7.11.1) trichostatin A results in decreased expression of AURKA mRNA decreases expression
mRNA 19606018
C012589 9212 AURKB
AIK2
AIM-1
AIM1
ARK2
AurB
IPL1
PPP1R48
STK12
STK5
aurkb-sv1
aurkb-sv2
aurora kinase B (EC:2.7.11.1) trichostatin A results in decreased expression of AURKB mRNA decreases expression
mRNA 19606018
C012589 563 AZGP1
ZA2G
ZAG
alpha-2-glycoprotein 1, zinc-binding decitabine inhibits the reaction [trichostatin A results in increased expression of AZGP1 mRNA] decreases reaction
/ increases expression
mRNA 18978557
C012589 563 AZGP1
ZA2G
ZAG
alpha-2-glycoprotein 1, zinc-binding trichostatin A results in increased expression of AZGP1 mRNA increases expression
mRNA 18978557
C012589 64343 AZI2
AZ2
NAP1
TILP
5-azacytidine induced 2 [decitabine co-treated with trichostatin A] results in decreased expression of AZI2 mRNA affects cotreatment
/ decreases expression
mRNA 17891453
C012589 578 BAK1
BAK
BAK-LIKE
BCL2L7
CDN1
BCL2-antagonist/killer 1 [perifosine co-treated with trichostatin A] results in decreased expression of BAK1 protein affects cotreatment
/ decreases expression
protein 15781658
C012589 581 BAX
BCL2L4
BCL2-associated X protein N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]] decreases reaction
/ increases expression
protein 19887557
C012589 581 BAX
BCL2L4
BCL2-associated X protein [perifosine co-treated with trichostatin A] results in increased activity of BAX protein affects cotreatment
/ increases activity
protein 15781658
C012589 581 BAX
BCL2L4
BCL2-associated X protein SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein] decreases reaction
/ increases expression
protein 19887557
C012589 581 BAX
BCL2L4
BCL2-associated X protein trichostatin A results in increased expression of BAX protein increases expression
protein 16010430
19887557
C012589 581 BAX
BCL2L4
BCL2-associated X protein Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]]] decreases reaction
/ increases expression
protein 19887557
C012589 27113 BBC3
JFY-1
JFY1
PUMA
BCL2 binding component 3 trichostatin A results in increased expression of BBC3 mRNA increases expression
mRNA 21527555
C012589 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 BCL2 protein results in decreased susceptibility to trichostatin A decreases response to substance
protein 21527555
C012589 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]] decreases expression
/ decreases reaction
protein 19887557
C012589 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [Plant Extracts co-treated with trichostatin A] results in decreased expression of BCL2 protein affects cotreatment
/ decreases expression
protein 18709356
C012589 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein] decreases expression
/ decreases reaction
protein 19887557
C012589 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 trichostatin A results in decreased expression of BCL2 protein decreases expression
protein 16010430
19887557
C012589 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]]] decreases expression
/ decreases reaction
protein 19887557
C012589 12044 trichostatin A inhibits the reaction [Nickel affects the expression of BCL2A1A mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 BCL2L1 protein results in decreased susceptibility to [bortezomib co-treated with trichostatin A] affects cotreatment
/ decreases response to substance
protein 16904634
C012589 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 BCL2L1 protein results in decreased susceptibility to trichostatin A decreases response to substance
protein 15781649
C012589 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]] decreases expression
/ decreases reaction
protein 19887557
C012589 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein] decreases expression
/ decreases reaction
protein 19887557
C012589 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 trichostatin A promotes the reaction [bortezomib results in decreased expression of BCL2L1 mRNA] decreases expression
/ increases reaction
mRNA 16904634
C012589 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 trichostatin A promotes the reaction [bortezomib results in decreased expression of BCL2L1 protein] decreases expression
/ increases reaction
protein 16904634
C012589 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 trichostatin A results in decreased expression of BCL2L1 protein decreases expression
protein 16009488
19887557
C012589 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]]] decreases expression
/ decreases reaction
protein 19887557
C012589 10018 BCL2L11
BAM
BIM
BOD
BCL2-like 11 (apoptosis facilitator) trichostatin A inhibits the reaction [Nickel affects the expression of BCL2L11 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 637 BID
FP497
BH3 interacting domain death agonist trichostatin A promotes the reaction [CASP9 protein affects the localization of BID protein] affects localization
/ increases reaction
protein 12556448
C012589 332 BIRC5
API4
EPR-1
baculoviral IAP repeat containing 5 decitabine inhibits the reaction [trichostatin A results in decreased expression of BIRC5 mRNA] decreases expression
/ decreases reaction
mRNA 18718068
C012589 332 BIRC5
API4
EPR-1
baculoviral IAP repeat containing 5 trichostatin A results in decreased expression of BIRC5 mRNA decreases expression
mRNA 18718068
19606018
C012589 648 BMI1
FLVI2/BMI1
PCGF4
RNF51
BMI1 polycomb ring finger oncogene [decitabine co-treated with trichostatin A] results in increased expression of BMI1 mRNA affects cotreatment
/ increases expression
mRNA 17185465
C012589 648 BMI1
FLVI2/BMI1
PCGF4
RNF51
BMI1 polycomb ring finger oncogene [decitabine co-treated with trichostatin A] results in increased expression of BMI1 protein affects cotreatment
/ increases expression
protein 17185465
C012589 1620 BRINP1
DBC1
DBCCR1
FAM5A
bone morphogenetic protein/retinoic acid inducible neural-specific 1 [decitabine co-treated with trichostatin A] inhibits the reaction [sodium arsenite affects the methylation of BRINP1 promoter] affects cotreatment
/ affects methylation
/ decreases reaction
promoter 18448484
C012589 55299 BRIX1
BRIX
BXDC2
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) trichostatin A inhibits the reaction [Nickel affects the expression of BRIX1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 686 BTD
biotinidase (EC:3.5.1.12) trichostatin A inhibits the reaction [chromium hexavalent ion results in decreased expression of BTD protein] decreases expression
/ decreases reaction
protein 21641978
C012589 686 BTD
biotinidase (EC:3.5.1.12) trichostatin A results in increased expression of BTD protein increases expression
protein 21641978
C012589 114904 C1QTNF6
CTFP6
CTRP6
ZACRP6
C1q and tumor necrosis factor related protein 6 [decitabine co-treated with trichostatin A] inhibits the reaction [sodium arsenite affects the methylation of C1QTNF6 promoter] affects cotreatment
/ affects methylation
/ decreases reaction
promoter 18448484
C012589 790 CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (EC:2.1.3.2 3.5.2.3 6.3.5.5) trichostatin A results in decreased expression of CAD mRNA decreases expression
mRNA 19606018
C012589 285782 CAGE1
CT3
CT95
CTAG3
bA69L16.7
cancer antigen 1 [decitabine co-treated with trichostatin A] results in increased expression of CAGE1 mRNA affects cotreatment
/ increases expression
mRNA 17891453
C012589 843 CASP10
ALPS2
FLICE2
MCH4
caspase 10, apoptosis-related cysteine peptidase (EC:3.4.22.63) [Genistein co-treated with trichostatin A] results in increased activity of CASP10 protein affects cotreatment
/ increases activity
protein 22626855
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [bortezomib co-treated with trichostatin A] results in increased cleavage of and results in increased activity of CASP3 protein affects cotreatment
/ increases activity
/ increases cleavage
protein 16904634
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [decitabine co-treated with trichostatin A] results in increased activity of CASP3 protein affects cotreatment
/ increases activity
protein 17019711
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [Genistein co-treated with trichostatin A] results in increased activity of CASP3 protein affects cotreatment
/ increases activity
protein 22626855
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]] decreases reaction
/ increases cleavage
protein 19887557
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) NR4A1 protein promotes the reaction [trichostatin A results in increased cleavage of CASP3 protein] increases cleavage
/ increases reaction
protein 21319187
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [perifosine co-treated with trichostatin A] results in increased activity of CASP3 protein affects cotreatment
/ increases activity
protein 15781658
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein] decreases reaction
/ increases cleavage
protein 19887557
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [trichostatin A co-treated with bortezomib] results in increased cleavage of CASP3 protein affects cotreatment
/ increases cleavage
protein 21345073
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) trichostatin A results in increased cleavage of and results in increased activity of CASP3 protein increases activity
/ increases cleavage
protein 16009488
16010430
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) trichostatin A results in increased cleavage of CASP3 protein increases cleavage
protein 19887557
21319187
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) trichostatin A results in increased expression of CASP3 mRNA increases expression
mRNA 16865256
C012589 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]]] decreases reaction
/ increases cleavage
protein 19887557
C012589 840 CASP7
CASP-7
CMH-1
ICE-LAP3
LICE2
MCH3
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) [bortezomib co-treated with trichostatin A] results in increased cleavage of and results in increased activity of CASP7 protein affects cotreatment
/ increases activity
/ increases cleavage
protein 16904634
C012589 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) [bortezomib co-treated with trichostatin A] results in increased cleavage of and results in increased activity of CASP8 protein affects cotreatment
/ increases activity
/ increases cleavage
protein 16904634
C012589 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) [[decitabine co-treated with trichostatin A] affects the methylation of CASP8 promoter] which affects the expression of CASP8 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18819746
C012589 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) [perifosine co-treated with trichostatin A] results in increased activity of CASP8 protein affects cotreatment
/ increases activity
protein 15781658
C012589 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) [trichostatin A co-treated with bortezomib] results in increased cleavage of CASP8 protein affects cotreatment
/ increases cleavage
protein 21345073
C012589 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) [bortezomib co-treated with trichostatin A] results in increased cleavage of and results in increased activity of CASP9 protein affects cotreatment
/ increases activity
/ increases cleavage
protein 16904634
C012589 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) [trichostatin A co-treated with bortezomib] results in increased cleavage of CASP9 protein affects cotreatment
/ increases cleavage
protein 21345073
C012589 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) trichostatin A promotes the reaction [CASP9 protein affects the localization of BID protein] affects localization
/ increases reaction
protein 12556448
C012589 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) trichostatin A results in increased cleavage of and results in increased activity of CASP9 protein increases activity
/ increases cleavage
protein 16010430
C012589 54897 CASZ1
CAS11
CST
SRG
ZNF693
dJ734G22.1
castor zinc finger 1 trichostatin A results in increased expression of CASZ1 mRNA increases expression
mRNA 17940511
C012589 6356 CCL11
SCYA11
chemokine (C-C motif) ligand 11 trichostatin A inhibits the reaction [Nickel affects the expression of CCL11 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 8900 CCNA1
cyclin A1 trichostatin A inhibits the reaction [MECP2 protein binds to CCNA1 promoter] affects binding
/ decreases reaction
promoter 17698632
C012589 8900 CCNA1
cyclin A1 trichostatin A promotes the reaction [HIST3H3 protein modified form binds to CCNA1 promoter] affects binding
/ increases reaction
promoter 17698632
C012589 8900 CCNA1
cyclin A1 trichostatin A promotes the reaction [HIST4H4 protein modified form binds to CCNA1 promoter] affects binding
/ increases reaction
promoter 17698632
C012589 8900 CCNA1
cyclin A1 trichostatin A results in decreased expression of CCNA1 mRNA decreases expression
mRNA 17698632
C012589 890 CCNA2
CCN1
CCNA
cyclin A2 trichostatin A results in decreased expression of CCNA2 protein decreases expression
protein 15179185
C012589 891 CCNB1
CCNB
cyclin B1 trichostatin A results in decreased expression of CCNB1 mRNA decreases expression
mRNA 19606018
C012589 891 CCNB1
CCNB
cyclin B1 trichostatin A results in decreased expression of CCNB1 protein decreases expression
protein 16009488
C012589 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 [3-deazaneplanocin co-treated with trichostatin A] affects the expression of CCND1 protein affects cotreatment
/ affects expression
protein 18538736
C012589 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 trichostatin A results in decreased expression of CCND1 protein decreases expression
protein 15179185
17431121
C012589 894 CCND2
KIAK0002
cyclin D2 trichostatin A results in increased expression of CCND2 protein increases expression
protein 16009488
C012589 896 CCND3
cyclin D3 trichostatin A results in increased expression of and results in increased stability of CCND3 protein increases expression
/ increases stability
protein 15179185
C012589 898 CCNE1
CCNE
cyclin E1 trichostatin A results in increased expression of CCNE1 protein increases expression
protein 15179185
C012589 729230 CCR2
CC-CKR-2
CCR-2
CCR2A
CCR2B
CD192
CKR2
CKR2A
CKR2B
CMKBR2
MCP-1-R
chemokine (C-C motif) receptor 2 trichostatin A inhibits the reaction [Nickel affects the expression of CCR2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1234 CCR5
CC-CKR-5
CCCKR5
CCR-5
CD195
CKR-5
CKR5
CMKBR5
IDDM22
chemokine (C-C motif) receptor 5 (gene/pseudogene) trichostatin A inhibits the reaction [Nickel affects the expression of CCR5 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1235 CCR6
BN-1
C-C_CKR-6
CC-CKR-6
CCR-6
CD196
CKR-L3
CKRL3
CMKBR6
DCR2
DRY6
GPR29
GPRCY4
STRL22
chemokine (C-C motif) receptor 6 trichostatin A inhibits the reaction [Nickel affects the expression of CCR6 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 929 CD14
CD14 molecule decitabine promotes the reaction [trichostatin A results in increased expression of CD14 mRNA] increases expression
/ increases reaction
mRNA 18718068
C012589 929 CD14
CD14 molecule trichostatin A results in increased expression of CD14 mRNA increases expression
mRNA 18718068
C012589 960 CD44
CDW44
CSPG8
ECMR-III
HCELL
HUTCH-I
IN
LHR
MC56
MDU2
MDU3
MIC4
Pgp1
CD44 molecule (Indian blood group) [3-deazaneplanocin co-treated with trichostatin A] affects the expression of CD44 protein affects cotreatment
/ affects expression
protein 18538736
C012589 960 CD44
CDW44
CSPG8
ECMR-III
HCELL
HUTCH-I
IN
LHR
MC56
MDU2
MDU3
MIC4
Pgp1
CD44 molecule (Indian blood group) trichostatin A inhibits the reaction [Nickel affects the expression of CD44 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4179 CD46
AHUS2
MCP
MIC10
TLX
TRA2.10
CD46 molecule, complement regulatory protein trichostatin A inhibits the reaction [Nickel affects the expression of CD46 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 994 CDC25B
cell division cycle 25B (EC:3.1.3.48) trichostatin A results in decreased expression of CDC25B mRNA decreases expression
mRNA 19606018
C012589 999 CDH1
Arc-1
CD324
CDHE
ECAD
LCAM
UVO
cadherin 1, type 1, E-cadherin (epithelial) [[decitabine co-treated with trichostatin A] affects the acetylation of HIST3H3 protein] which affects the expression of CDH1 mRNA affects acetylation
/ affects cotreatment
/ affects expression
mRNA 18584348
C012589 999 CDH1
Arc-1
CD324
CDHE
ECAD
LCAM
UVO
cadherin 1, type 1, E-cadherin (epithelial) [trichostatin A affects the acetylation of HIST3H3 protein] which affects the expression of CDH1 mRNA affects acetylation
/ affects expression
mRNA 18584348
C012589 999 CDH1
Arc-1
CD324
CDHE
ECAD
LCAM
UVO
cadherin 1, type 1, E-cadherin (epithelial) trichostatin A inhibits the reaction [chromium hexavalent ion results in decreased expression of CDH1 protein] decreases expression
/ decreases reaction
protein 23518002
C012589 999 CDH1
Arc-1
CD324
CDHE
ECAD
LCAM
UVO
cadherin 1, type 1, E-cadherin (epithelial) trichostatin A results in increased expression of CDH1 protein increases expression
protein 18025290
C012589 1009 CDH11
CAD11
CDHOB
OB
OSF-4
cadherin 11, type 2, OB-cadherin (osteoblast) trichostatin A results in decreased expression of CDH11 mRNA decreases expression
mRNA 18025290
C012589 1009 CDH11
CAD11
CDHOB
OB
OSF-4
cadherin 11, type 2, OB-cadherin (osteoblast) trichostatin A results in decreased expression of CDH11 protein decreases expression
protein 18025290
C012589 1012 CDH13
CDHH
P105
cadherin 13 (EC:3.6.1.3) [trichostatin A affects the acetylation of CDH13 gene] which affects the expression of CDH13 mRNA affects acetylation
/ affects expression
gene / mRNA 18553387
C012589 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) trichostatin A results in decreased expression of CDK1 mRNA decreases expression
mRNA 19606018
C012589 1019 CDK4
CMM3
PSK-J3
cyclin-dependent kinase 4 (EC:2.7.11.22) trichostatin A results in decreased expression of CDK4 mRNA decreases expression
mRNA 19606018
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) [decitabine co-treated with trichostatin A] affects the expression of CDKN1A mRNA affects cotreatment
/ affects expression
mRNA 17185465
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) [decitabine co-treated with trichostatin A] results in increased expression of CDKN1A protein affects cotreatment
/ increases expression
protein 17185465
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Hydroxyurea inhibits the reaction [trichostatin A results in increased expression of CDKN1A protein] decreases reaction
/ increases expression
protein 17653085
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Tretinoin promotes the reaction [trichostatin A results in increased expression of CDKN1A mRNA] increases expression
/ increases reaction
mRNA 17431121
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Tretinoin promotes the reaction [trichostatin A results in increased expression of CDKN1A protein] increases expression
/ increases reaction
protein 17431121
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) [trichostatin A affects the expression of DNMT3B protein] which affects the expression of CDKN1A mRNA affects expression
mRNA 18544619
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) [trichostatin A co-treated with bortezomib] results in increased expression of CDKN1A mRNA affects cotreatment
/ increases expression
mRNA 21345073
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) [trichostatin A co-treated with bortezomib] results in increased expression of CDKN1A protein affects cotreatment
/ increases expression
protein 21345073
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) trichostatin A promotes the reaction [decitabine results in increased expression of CDKN1A mRNA] increases expression
/ increases reaction
mRNA 16043219
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) trichostatin A promotes the reaction [decitabine results in increased expression of CDKN1A protein] increases expression
/ increases reaction
protein 18223691
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) trichostatin A results in increased expression of CDKN1A mRNA increases expression
mRNA 16865256
17431121
19606018
C012589 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) trichostatin A results in increased expression of CDKN1A protein increases expression
protein 15179185
16009488
16051188
17230511
17431121
17653085
18223691
19234609
C012589 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) [decitabine co-treated with trichostatin A] results in increased expression of CDKN1B mRNA affects cotreatment
/ increases expression
mRNA 17185465
C012589 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) Tretinoin promotes the reaction [trichostatin A results in increased expression of CDKN1B mRNA] increases expression
/ increases reaction
mRNA 17431121
C012589 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) Tretinoin promotes the reaction [trichostatin A results in increased expression of CDKN1B protein] increases expression
/ increases reaction
protein 17431121
C012589 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) [trichostatin A affects the expression of DNMT3B protein] which affects the expression of CDKN1B mRNA affects expression
mRNA 18544619
C012589 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) trichostatin A results in increased expression of CDKN1B mRNA increases expression
mRNA 17431121
C012589 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) trichostatin A results in increased expression of CDKN1B protein increases expression
protein 17431121
C012589 1029 CDKN2A
ARF
CDK4I
CDKN2
CMM2
INK4
INK4A
MLM
MTS-1
MTS1
P14
P14ARF
P16
P16-INK4A
P16INK4
P16INK4A
P19
P19ARF
TP16
cyclin-dependent kinase inhibitor 2A [decitabine co-treated with trichostatin A] affects the expression of CDKN2A protein affects cotreatment
/ affects expression
protein 17019711
C012589 1029 CDKN2A
ARF
CDK4I
CDKN2
CMM2
INK4
INK4A
MLM
MTS-1
MTS1
P14
P14ARF
P16
P16-INK4A
P16INK4
P16INK4A
P19
P19ARF
TP16
cyclin-dependent kinase inhibitor 2A [decitabine co-treated with trichostatin A] affects the methylation of CDKN2A promoter affects cotreatment
/ affects methylation
promoter 18069755
C012589 1029 CDKN2A
ARF
CDK4I
CDKN2
CMM2
INK4
INK4A
MLM
MTS-1
MTS1
P14
P14ARF
P16
P16-INK4A
P16INK4
P16INK4A
P19
P19ARF
TP16
cyclin-dependent kinase inhibitor 2A [[decitabine co-treated with trichostatin A] affects the methylation of CDKN2A promoter] which affects the expression of CDKN2A mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18813790
C012589 1029 CDKN2A
ARF
CDK4I
CDKN2
CMM2
INK4
INK4A
MLM
MTS-1
MTS1
P14
P14ARF
P16
P16-INK4A
P16INK4
P16INK4A
P19
P19ARF
TP16
cyclin-dependent kinase inhibitor 2A trichostatin A results in decreased expression of CDKN2A mRNA decreases expression
mRNA 19606018
C012589 1030 CDKN2B
CDK4I
INK4B
MTS2
P15
TP15
p15INK4b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) decitabine promotes the reaction [trichostatin A results in increased expression of CDKN2B mRNA] increases expression
/ increases reaction
mRNA 18718068
C012589 1030 CDKN2B
CDK4I
INK4B
MTS2
P15
TP15
p15INK4b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) trichostatin A results in increased expression of CDKN2B mRNA increases expression
mRNA 18718068
C012589 1045 CDX2
CDX-3
CDX3
caudal type homeobox 2 trichostatin A promotes the reaction [decitabine results in increased expression of CDX2 mRNA] increases expression
/ increases reaction
mRNA 16990345
C012589 1046 CDX4
caudal type homeobox 4 trichostatin A inhibits the reaction [Nickel affects the expression of CDX4 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1051 CEBPB
C/EBP-beta
CRP2
IL6DBP
LAP
LIP
NF-IL6
TCF5
CCAAT/enhancer binding protein (C/EBP), beta trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPB mRNA] decreases reaction
/ increases expression
mRNA 21911040
C012589 10752 CHL1
CALL
L1CAM2
cell adhesion molecule L1-like trichostatin A inhibits the reaction [Nickel affects the expression of CHL1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1132 CHRM4
HM4
M4R
cholinergic receptor, muscarinic 4 trichostatin A inhibits the reaction [Nickel affects the expression of CHRM4 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1365 CLDN3
C7orf1
CPE-R2
CPETR2
HRVP1
RVP1
claudin 3 [decitabine co-treated with trichostatin A] inhibits the reaction [MBD2 protein binds to CLDN3 promoter] affects binding
/ affects cotreatment
/ decreases reaction
promoter 17986852
C012589 1365 CLDN3
C7orf1
CPE-R2
CPETR2
HRVP1
RVP1
claudin 3 [decitabine co-treated with trichostatin A] promotes the reaction [SP1 protein binds to CLDN3 promoter] affects binding
/ affects cotreatment
/ increases reaction
promoter 17986852
C012589 1365 CLDN3
C7orf1
CPE-R2
CPETR2
HRVP1
RVP1
claudin 3 [decitabine co-treated with trichostatin A] promotes the reaction [SP3 protein binds to CLDN3 promoter] affects binding
/ affects cotreatment
/ increases reaction
promoter 17986852
C012589 1365 CLDN3
C7orf1
CPE-R2
CPETR2
HRVP1
RVP1
claudin 3 trichostatin A inhibits the reaction [Nickel affects the expression of CLDN3 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1365 CLDN3
C7orf1
CPE-R2
CPETR2
HRVP1
RVP1
claudin 3 trichostatin A promotes the reaction [decitabine results in increased expression of CLDN3 mRNA] increases expression
/ increases reaction
mRNA 17986852
C012589 1365 CLDN3
C7orf1
CPE-R2
CPETR2
HRVP1
RVP1
claudin 3 trichostatin A promotes the reaction [decitabine results in increased expression of CLDN3 protein] increases expression
/ increases reaction
protein 17986852
C012589 7122 CLDN5
AWAL
BEC1
CPETRL1
TMVCF
claudin 5 trichostatin A inhibits the reaction [Nickel affects the expression of CLDN5 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 9074 CLDN6
claudin 6 [trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN6 promoter affects cotreatment
/ decreases methylation
promoter 18661270
C012589 9074 CLDN6
claudin 6 trichostatin A results in decreased methylation of CLDN6 promoter decreases methylation
promoter 18661270
C012589 9074 CLDN6
claudin 6 trichostatin A results in increased expression of CLDN6 mRNA increases expression
mRNA 18661270
C012589 9073 CLDN8
claudin 8 trichostatin A results in increased expression of CLDN8 mRNA increases expression
mRNA 18661270
C012589 9080 CLDN9
claudin 9 [trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN9 promoter affects cotreatment
/ decreases methylation
promoter 18661270
C012589 9080 CLDN9
claudin 9 trichostatin A results in decreased methylation of CLDN9 promoter decreases methylation
promoter 18661270
C012589 9080 CLDN9
claudin 9 trichostatin A results in increased expression of CLDN9 mRNA increases expression
mRNA 18661270
C012589 1192 CLIC1
G6
NCC27
chloride intracellular channel 1 trichostatin A results in decreased expression of CLIC1 protein decreases expression
protein 19294695
C012589 1191 CLU
APO-J
APOJ
CLI
CLU1
CLU2
KUB1
NA1/NA2
SGP-2
SGP2
SP-40
TRPM-2
TRPM2
clusterin trichostatin A inhibits the reaction [Nickel affects the expression of CLU mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1191 CLU
APO-J
APOJ
CLI
CLU1
CLU2
KUB1
NA1/NA2
SGP-2
SGP2
SP-40
TRPM-2
TRPM2
clusterin trichostatin A results in increased expression of CLU protein increases expression
protein 19234609
C012589 1329 COX5B
COXVB
cytochrome c oxidase subunit Vb (EC:1.9.3.1) trichostatin A results in increased expression of COX5B protein increases expression
protein 19294695
C012589 1387 CREBBP
CBP
KAT3A
RSTS
CREB binding protein (EC:2.3.1.48) trichostatin A promotes the reaction [CREBBP protein binds to PDK4 promoter] affects binding
/ increases reaction
protein 16757381
C012589 1390 CREM
CREM-2
ICER
hCREM-2
cAMP responsive element modulator trichostatin A inhibits the reaction [Nickel affects the expression of CREM mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1399 CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like trichostatin A inhibits the reaction [Nickel affects the expression of CRKL mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1437 CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage) [trichostatin A co-treated with Dexamethasone] inhibits the reaction [IL1B protein promotes the reaction [HIST4H4 protein modified form binds to CSF2 promoter]] affects binding
/ affects cotreatment
/ decreases reaction
/ increases reaction
promoter 12070353
C012589 1437 CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage) trichostatin A inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]] decreases reaction
/ increases secretion
protein 12070353
C012589 1437 CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage) trichostatin A inhibits the reaction [[Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]] affects cotreatment
/ decreases reaction
/ increases secretion
protein 12070353
C012589 1474 CST6
cystatin E/M trichostatin A results in increased expression of CST6 mRNA increases expression
mRNA 19503093
C012589 1474 CST6
cystatin E/M trichostatin A results in increased expression of CST6 protein increases expression
protein 19503093
C012589 1490 CTGF
CCN2
HCS24
IGFBP8
NOV2
connective tissue growth factor trichostatin A results in increased expression of CTGF mRNA increases expression
mRNA 19606018
C012589 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa [3-deazaneplanocin co-treated with trichostatin A] affects the expression of CTNNB1 protein affects cotreatment
/ affects expression
protein 18538736
C012589 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa trichostatin A inhibits the reaction [butylbenzyl phthalate affects the localization of CTNNB1 protein] affects localization
/ decreases reaction
protein 22552774
C012589 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa trichostatin A inhibits the reaction [Dibutyl Phthalate affects the localization of CTNNB1 protein] affects localization
/ decreases reaction
protein 22552774
C012589 1503 CTPS1
CTPS
CTP synthase 1 (EC:6.3.4.2) trichostatin A results in decreased expression of CTPS1 mRNA decreases expression
mRNA 19606018
C012589 6376 CX3CL1
ABCD-3
C3Xkine
CXC3
CXC3C
NTN
NTT
SCYD1
fractalkine
neurotactin
chemokine (C-X3-C motif) ligand 1 trichostatin A inhibits the reaction [Nickel affects the expression of CX3CL1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1525 CXADR
CAR
CAR4/6
HCAR
coxsackie virus and adenovirus receptor decitabine promotes the reaction [trichostatin A results in increased expression of CXADR mRNA] increases expression
/ increases reaction
mRNA 18618240
C012589 1525 CXADR
CAR
CAR4/6
HCAR
coxsackie virus and adenovirus receptor decitabine promotes the reaction [trichostatin A results in increased expression of CXADR mRNA alternative form] increases expression
/ increases reaction
mRNA 18618240
C012589 1525 CXADR
CAR
CAR4/6
HCAR
coxsackie virus and adenovirus receptor trichostatin A results in increased expression of CXADR mRNA increases expression
mRNA 18618240
C012589 1525 CXADR
CAR
CAR4/6
HCAR
coxsackie virus and adenovirus receptor trichostatin A results in increased expression of CXADR mRNA alternative form increases expression
mRNA 18618240
C012589 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 trichostatin A results in increased expression of CXCL12 mRNA increases expression
mRNA 19289100
C012589 9547 CXCL14
BMAC
BRAK
KEC
KS1
MIP-2g
MIP2G
NJAC
SCYB14
chemokine (C-X-C motif) ligand 14 trichostatin A results in decreased acetylation of CXCL14 protein decreases acetylation
protein 20562917
C012589 6374 CXCL5
ENA-78
SCYB5
chemokine (C-X-C motif) ligand 5 trichostatin A results in decreased acetylation of CXCL5 protein decreases acetylation
protein 20562917
C012589 7852 CXCR4
CD184
D2S201E
FB22
HM89
HSY3RR
LAP3
LCR1
LESTR
NPY3R
NPYR
NPYRL
NPYY3R
WHIM
chemokine (C-X-C motif) receptor 4 [decitabine co-treated with trichostatin A] results in increased expression of CXCR4 mRNA affects cotreatment
/ increases expression
mRNA 17616702
C012589 54205 CYCS
CYC
HCS
THC4
cytochrome c, somatic [perifosine co-treated with trichostatin A] affects the localization of CYCS protein affects cotreatment
/ affects localization
protein 15781658
C012589 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) trichostatin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] decreases reaction
/ increases expression
mRNA 15713371
C012589 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) trichostatin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] increases expression
/ increases reaction
mRNA 12927368
C012589 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) trichostatin A results in increased activity of CYP1A1 protein increases activity
protein 15713371
C012589 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) trichostatin A results in increased expression of CYP1A1 mRNA increases expression
mRNA 12927368
C012589 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) trichostatin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] increases expression
/ increases reaction
mRNA 12927368
C012589 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) trichostatin A results in increased expression of CYP1A2 mRNA increases expression
mRNA 12927368
C012589 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) trichostatin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] decreases reaction
/ increases expression
mRNA 15713371
C012589 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) trichostatin A inhibits the reaction [Nickel affects the expression of CYP1B1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) trichostatin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] increases expression
/ increases reaction
mRNA 12927368
C012589 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) trichostatin A results in increased expression of CYP1B1 mRNA increases expression
mRNA 12927368
C012589 1591 CYP24A1
CP24
CYP24
HCAI
P450-CC24
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) trichostatin A inhibits the reaction [Nickel affects the expression of CYP24A1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1591 CYP24A1
CP24
CYP24
HCAI
P450-CC24
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) trichostatin A promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] increases expression
/ increases reaction
mRNA 21115105
C012589 1591 CYP24A1
CP24
CYP24
HCAI
P450-CC24
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) trichostatin A promotes the reaction [Valproic Acid promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]] increases expression
/ increases reaction
mRNA 21115105
C012589 29785 CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1 (EC:1.14.14.1) trichostatin A inhibits the reaction [Dexamethasone results in decreased expression of CYP2S1 mRNA] decreases expression
/ decreases reaction
mRNA 22155357
C012589 13119 trichostatin A inhibits the reaction [Nickel affects the expression of CYP4A14 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 147906 DACT3
DAPPER3
RRR1
dishevelled-binding antagonist of beta-catenin 3 [[3-deazaneplanocin co-treated with trichostatin A] affects the acetylation of and affects the methylation of HIST3H3 protein] which affects the expression of DACT3 affects acetylation
/ affects cotreatment
/ affects expression
/ affects methylation
18538736
C012589 147906 DACT3
DAPPER3
RRR1
dishevelled-binding antagonist of beta-catenin 3 [[3-deazaneplanocin co-treated with trichostatin A] affects the acetylation of and affects the methylation of HIST4H4 protein] which affects the expression of DACT3 affects acetylation
/ affects cotreatment
/ affects expression
/ affects methylation
18538736
C012589 147906 DACT3
DAPPER3
RRR1
dishevelled-binding antagonist of beta-catenin 3 [3-deazaneplanocin co-treated with trichostatin A] affects the expression of DACT3 mRNA affects cotreatment
/ affects expression
mRNA 18538736
C012589 147906 DACT3
DAPPER3
RRR1
dishevelled-binding antagonist of beta-catenin 3 [3-deazaneplanocin co-treated with trichostatin A] affects the expression of DACT3 protein affects cotreatment
/ affects expression
protein 18538736
C012589 147906 DACT3
DAPPER3
RRR1
dishevelled-binding antagonist of beta-catenin 3 trichostatin A affects the expression of DACT3 mRNA affects expression
mRNA 18538736
C012589 1612 DAPK1
DAPK
death-associated protein kinase 1 (EC:2.7.11.1) trichostatin A results in increased expression of DAPK1 mRNA increases expression
mRNA 16865256
C012589 23604 DAPK2
DRP-1
DRP1
death-associated protein kinase 2 (EC:2.7.11.1) trichostatin A results in increased expression of DAPK2 mRNA increases expression
mRNA 16865256
C012589 131566 DCBLD2
CLCP1
ESDN
discoidin, CUB and LCCL domain containing 2 [[decitabine co-treated with trichostatin A] affects the methylation of DCBLD2 promoter] which affects the expression of DCBLD2 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18314483
C012589 131566 DCBLD2
CLCP1
ESDN
discoidin, CUB and LCCL domain containing 2 [[decitabine co-treated with trichostatin A] affects the methylation of DCBLD2 promoter] which affects the expression of DCBLD2 protein affects cotreatment
/ affects expression
/ affects methylation
promoter / protein 18314483
C012589 131566 DCBLD2
CLCP1
ESDN
discoidin, CUB and LCCL domain containing 2 [trichostatin A affects the methylation of DCBLD2 promoter] which affects the expression of DCBLD2 mRNA affects expression
/ affects methylation
mRNA / promoter 18314483
C012589 131566 DCBLD2
CLCP1
ESDN
discoidin, CUB and LCCL domain containing 2 [trichostatin A affects the methylation of DCBLD2 promoter] which affects the expression of DCBLD2 protein affects expression
/ affects methylation
promoter / protein 18314483
C012589 1630 DCC
CRC18
CRCR1
IGDCC1
MRMV1
deleted in colorectal carcinoma trichostatin A inhibits the reaction [Nickel affects the expression of DCC mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1638 DCT
TRP-2
TYRP2
dopachrome tautomerase (EC:5.3.3.12) trichostatin A inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DCT mRNA] decreases expression
/ decreases reaction
mRNA 15892717
C012589 1638 DCT
TRP-2
TYRP2
dopachrome tautomerase (EC:5.3.3.12) trichostatin A inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DCT protein] decreases expression
/ decreases reaction
protein 15892717
C012589 10202 DHRS2
HEP27
SDR25C1
dehydrogenase/reductase (SDR family) member 2 trichostatin A results in increased expression of DHRS2 mRNA increases expression
mRNA 19606018
C012589 3337 DNAJB1
HSPF1
Hdj1
Hsp40
RSPH16B
Sis1
DnaJ (Hsp40) homolog, subfamily B, member 1 trichostatin A results in increased expression of DNAJB1 mRNA increases expression
mRNA 19606018
C012589 1789 DNMT3B
ICF
ICF1
M.HsaIIIB
DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) trichostatin A affects the expression of DNMT3B mRNA affects expression
mRNA 18544619
C012589 1789 DNMT3B
ICF
ICF1
M.HsaIIIB
DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) [trichostatin A affects the expression of DNMT3B protein] which affects the expression of CDKN1A mRNA affects expression
protein 18544619
C012589 1789 DNMT3B
ICF
ICF1
M.HsaIIIB
DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) [trichostatin A affects the expression of DNMT3B protein] which affects the expression of CDKN1B mRNA affects expression
protein 18544619
C012589 1789 DNMT3B
ICF
ICF1
M.HsaIIIB
DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) [trichostatin A affects the expression of DNMT3B protein] which affects the expression of RB1 mRNA affects expression
protein 18544619
C012589 151871 DPPA2
CT100
ECAT15-2
PESCRG1
developmental pluripotency associated 2 trichostatin A inhibits the reaction [Nickel affects the expression of DPPA2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]] decreases reaction
/ increases expression
mutant form 21911040
C012589 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]] decreases reaction
/ increases chemical synthesis
/ increases expression
mutant form 21911040
C012589 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JUN protein]] decreases reaction
/ increases phosphorylation
mutant form 21911040
C012589 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]] decreases reaction
/ increases phosphorylation
mutant form 21911040
C012589 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]] decreases reaction
/ increases phosphorylation
mutant form 21911040
C012589 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]] decreases reaction
/ increases phosphorylation
mutant form 21911040
C012589 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) trichostatin A promotes the reaction [arsenite results in increased expression of DUSP1 mRNA] increases expression
/ increases reaction
mRNA 11689710
C012589 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) trichostatin A results in increased activity of DUSP1 protein increases activity
protein 21911040
C012589 1855 DVL1
DVL
DVL1L1
DVL1P1
dishevelled segment polarity protein 1 [decitabine co-treated with trichostatin A] results in decreased expression of DVL1 mRNA affects cotreatment
/ decreases expression
mRNA 17891453
C012589 1856 DVL2
dishevelled segment polarity protein 2 [3-deazaneplanocin co-treated with trichostatin A] affects the expression of DVL2 protein affects cotreatment
/ affects expression
protein 18538736
C012589 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 [Doxorubicin co-treated with trichostatin A] results in increased expression of EGR1 mRNA affects cotreatment
/ increases expression
mRNA 17330857
C012589 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 EGR1 protein affects the reaction [trichostatin A affects the expression of GDF15 mRNA] affects expression
/ affects reaction
protein 18801729
C012589 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 EGR1 protein affects the susceptibility to [Doxorubicin co-treated with trichostatin A] affects cotreatment
/ affects response to substance
protein 17330857
C012589 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 trichostatin A affects the expression of EGR1 mRNA affects expression
mRNA 18801729
C012589 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 trichostatin A affects the expression of EGR1 protein affects expression
protein 18801729
C012589 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 trichostatin A promotes the reaction [[EP300 protein co-treated with EGR1 protein] results in increased expression of PTEN mRNA] affects cotreatment
/ increases expression
/ increases reaction
protein 17330857
C012589 1978 EIF4EBP1
4E-BP1
4EBP1
BP-1
PHAS-I
eukaryotic translation initiation factor 4E binding protein 1 [trichostatin A co-treated with bortezomib] results in decreased phosphorylation of EIF4EBP1 protein affects cotreatment
/ decreases phosphorylation
protein 21345073
C012589 1982 EIF4G2
AAG1
DAP5
NAT1
P97
eukaryotic translation initiation factor 4 gamma, 2 trichostatin A results in decreased expression of EIF4G2 mRNA decreases expression
mRNA 19606018
C012589 1994 ELAVL1
ELAV1
HUR
Hua
MelG
ELAV like RNA binding protein 1 [decitabine co-treated with trichostatin A] affects the localization of ELAVL1 protein affects cotreatment
/ affects localization
protein 17891453
C012589 2002 ELK1
ELK1, member of ETS oncogene family trichostatin A results in increased activity of ELK1 protein increases activity
protein 15103026
C012589 2002 ELK1
ELK1, member of ETS oncogene family U 0126 inhibits the reaction [trichostatin A results in increased activity of ELK1 protein] decreases reaction
/ increases activity
protein 15103026
C012589 22936 ELL2
elongation factor, RNA polymerase II, 2 trichostatin A inhibits the reaction [Nickel affects the expression of ELL2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 133418 EMB
embigin trichostatin A inhibits the reaction [Nickel affects the expression of EMB mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 8507 ENC1
CCL28
ENC-1
KLHL35
KLHL37
NRPB
PIG10
TP53I10
ectodermal-neural cortex 1 (with BTB domain) [[decitabine co-treated with trichostatin A] affects the methylation of ENC1 promoter] which affects the expression of ENC1 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18803327
C012589 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) trichostatin A affects the localization of EP300 protein affects localization
protein 15647279
C012589 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) trichostatin A promotes the reaction [EP300 protein binds to APEX1 protein] affects binding
/ increases reaction
protein 20856196
C012589 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) trichostatin A promotes the reaction [EP300 protein binds to TGFBR2 promoter] affects binding
/ increases reaction
protein 15647279
C012589 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) trichostatin A promotes the reaction [[EP300 protein co-treated with EGR1 protein] results in increased expression of PTEN mRNA] affects cotreatment
/ increases expression
/ increases reaction
protein 17330857
C012589 2045 EPHA7
EHK3
HEK11
EPH receptor A7 (EC:2.7.10.1) trichostatin A inhibits the reaction [Nickel affects the expression of EPHA7 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 2078 ERG
erg-3
p55
v-ets avian erythroblastosis virus E26 oncogene homolog trichostatin A results in decreased expression of ERG mRNA decreases expression
mRNA 19805354
C012589 54206 ERRFI1
GENE-33
MIG-6
MIG6
RALT
ERBB receptor feedback inhibitor 1 trichostatin A results in increased expression of ERRFI1 mRNA increases expression
mRNA 17940511
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [decitabine co-treated with trichostatin A] affects the expression of ESR1 mRNA affects cotreatment
/ affects expression
mRNA 18264725
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [decitabine co-treated with trichostatin A] promotes the reaction [TFAP2C protein binds to ESR1 promoter] affects binding
/ affects cotreatment
/ increases reaction
promoter 19458056
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [decitabine co-treated with trichostatin A] promotes the reaction [TFAP2C protein results in increased expression of ESR1 mRNA] affects cotreatment
/ increases expression
/ increases reaction
mRNA 19458056
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [decitabine co-treated with trichostatin A] results in decreased expression of ESR1 mRNA affects cotreatment
/ decreases expression
mRNA 17891453
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [decitabine co-treated with trichostatin A] results in decreased expression of ESR1 protein affects cotreatment
/ decreases expression
protein 17891453
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [decitabine co-treated with trichostatin A] results in decreased stability of ESR1 mRNA affects cotreatment
/ decreases stability
mRNA 17891453
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [decitabine co-treated with trichostatin A] results in increased expression of ESR1 mRNA affects cotreatment
/ increases expression
mRNA 17533736
19458056
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 decitabine promotes the reaction [trichostatin A results in increased expression of ESR1 mRNA] increases expression
/ increases reaction
mRNA 18092350
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 TFAP2C protein promotes the reaction [[decitabine co-treated with trichostatin A] results in increased expression of ESR1 mRNA] affects cotreatment
/ increases expression
/ increases reaction
mRNA 19458056
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [trichostatin A co-treated with TFAP2C protein] results in increased expression of ESR1 mRNA affects cotreatment
/ increases expression
mRNA 19458056
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 trichostatin A results in decreased expression of ESR1 mRNA decreases expression
mRNA 17891453
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 trichostatin A results in decreased expression of ESR1 protein decreases expression
protein 17891453
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 trichostatin A results in decreased stability of ESR1 mRNA decreases stability
mRNA 17891453
C012589 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 trichostatin A results in increased expression of ESR1 mRNA increases expression
mRNA 18092350
C012589 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) [decitabine co-treated with trichostatin A] results in decreased methylation of ESR2 promoter affects cotreatment
/ decreases methylation
promoter 19331143
C012589 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) [decitabine co-treated with trichostatin A] results in increased expression of ESR2 mRNA affects cotreatment
/ increases expression
mRNA 19331143
C012589 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) decitabine promotes the reaction [trichostatin A results in increased expression of ESR2 mRNA] increases expression
/ increases reaction
mRNA 18092350
C012589 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) decitabine promotes the reaction [trichostatin A results in increased expression of ESR2 protein] increases expression
/ increases reaction
protein 18092350
C012589 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) trichostatin A promotes the reaction [Estradiol results in increased activity of ESR2 protein] increases activity
/ increases reaction
protein 15103026
C012589 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) trichostatin A results in decreased methylation of ESR2 promoter decreases methylation
promoter 19331143
C012589 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) trichostatin A results in increased expression of ESR2 mRNA increases expression
mRNA 18092350
19331143
C012589 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) trichostatin A results in increased expression of ESR2 protein increases expression
protein 18092350
C012589 2101 ESRRA
ERR1
ERRa
ERRalpha
ESRL1
NR3B1
estrogen-related receptor alpha trichostatin A results in increased activity of ESRRA protein increases activity
protein 11705994
C012589 2104 ESRRG
ERR3
ERRgamma
NR3B3
estrogen-related receptor gamma trichostatin A results in increased activity of ESRRG protein increases activity
protein 11705994
C012589 81889 FAHD1
C16orf36
YISKL
fumarylacetoacetate hydrolase domain containing 1 (EC:3.7.1.5) trichostatin A inhibits the reaction [Nickel affects the expression of FAHD1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 84985 FAM83A
BJ-TSA-9
family with sequence similarity 83, member A [decitabine co-treated with trichostatin A] inhibits the reaction [sodium arsenite affects the methylation of FAM83A promoter] affects cotreatment
/ affects methylation
/ decreases reaction
promoter 18448484
C012589 355 FAS
ALPS1A
APO-1
APT1
CD95
FAS1
FASTM
TNFRSF6
Fas cell surface death receptor decitabine promotes the reaction [trichostatin A results in increased expression of FAS mRNA] increases expression
/ increases reaction
mRNA 18718068
C012589 355 FAS
ALPS1A
APO-1
APT1
CD95
FAS1
FASTM
TNFRSF6
Fas cell surface death receptor trichostatin A results in increased expression of FAS mRNA increases expression
mRNA 18718068
C012589 2203 FBP1
FBP
fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) [trichostatin A affects the methylation of FBP1 promoter] which affects the expression of FBP1 mRNA affects expression
/ affects methylation
mRNA / promoter 18938139
C012589 8789 FBP2
fructose-1,6-bisphosphatase 2 (EC:3.1.3.11) [trichostatin A affects the methylation of FBP2 promoter] which affects the expression of FBP2 mRNA affects expression
/ affects methylation
mRNA / promoter 18938139
C012589 26291 FGF21
fibroblast growth factor 21 trichostatin A results in increased expression of FGF21 mRNA increases expression
mRNA 22338096
C012589 26291 FGF21
fibroblast growth factor 21 trichostatin A results in increased expression of FGF21 protein increases expression
protein 22338096
C012589 2272 FHIT
AP3Aase
FRA3B
fragile histidine triad (EC:3.6.1.29) [decitabine co-treated with trichostatin A] affects the expression of FHIT protein affects cotreatment
/ affects expression
protein 17019711
C012589 2350 FOLR2
BETA-HFR
FBP
FBP/PL-1
FR-BETA
FR-P3
folate receptor 2 (fetal) trichostatin A promotes the reaction [Tretinoin inhibits the reaction [RARG protein binds to FOLR2 promoter]] affects binding
/ decreases reaction
/ increases reaction
promoter 16740727
C012589 2350 FOLR2
BETA-HFR
FBP
FBP/PL-1
FR-BETA
FR-P3
folate receptor 2 (fetal) trichostatin A promotes the reaction [Tretinoin promotes the reaction [SP1 protein binds to FOLR2 promoter]] affects binding
/ increases reaction
promoter 16740727
C012589 2350 FOLR2
BETA-HFR
FBP
FBP/PL-1
FR-BETA
FR-P3
folate receptor 2 (fetal) trichostatin A promotes the reaction [Tretinoin results in increased expression of FOLR2 mRNA] increases expression
/ increases reaction
mRNA 16740727
C012589 2350 FOLR2
BETA-HFR
FBP
FBP/PL-1
FR-BETA
FR-P3
folate receptor 2 (fetal) trichostatin A promotes the reaction [Tretinoin results in increased expression of FOLR2 protein] increases expression
/ increases reaction
protein 16740727
C012589 3169 FOXA1
HNF3A
TCF3A
forkhead box A1 [decitabine co-treated with trichostatin A] results in decreased expression of FOXA1 mRNA affects cotreatment
/ decreases expression
mRNA 17891453
C012589 27023 FOXB1
FKH5
HFKH-5
forkhead box B1 trichostatin A inhibits the reaction [Nickel affects the expression of FOXB1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 2296 FOXC1
ARA
FKHL7
FREAC-3
FREAC3
IGDA
IHG1
IRID1
RIEG3
forkhead box C1 [decitabine co-treated with trichostatin A] results in increased expression of FOXC1 mRNA affects cotreatment
/ increases expression
mRNA 17891453
C012589 221937 FOXK1
FOXK1L
forkhead box K1 [decitabine co-treated with trichostatin A] results in decreased expression of FOXK1 mRNA affects cotreatment
/ decreases expression
mRNA 17891453
C012589 5349 FXYD3
MAT8
PLML
FXYD domain containing ion transport regulator 3 trichostatin A inhibits the reaction [Nickel affects the expression of FXYD3 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 8322 FZD4
CD344
EVR1
FEVR
FZD4S
Fz-4
Fz4
FzE4
GPCR
hFz4
frizzled family receptor 4 trichostatin A inhibits the reaction [Nickel affects the expression of FZD4 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 2597 GAPDH
G3PD
GAPD
glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) trichostatin A results in decreased expression of GAPDH protein decreases expression
protein 19294695
C012589 2623 GATA1
ERYF1
GATA-1
GF-1
GF1
NF-E1
NFE1
XLANP
XLTDA
XLTT
GATA binding protein 1 (globin transcription factor 1) [decitabine co-treated with trichostatin A] results in increased expression of GATA1 mRNA affects cotreatment
/ increases expression
mRNA 17185465
C012589 2624 GATA2
DCML
MONOMAC
NFE1B
GATA binding protein 2 [decitabine co-treated with trichostatin A] results in increased expression of GATA2 mRNA affects cotreatment
/ increases expression
mRNA 17185465
C012589 2625 GATA3
HDR
HDRS
GATA binding protein 3 [decitabine co-treated with trichostatin A] results in decreased expression of GATA3 mRNA affects cotreatment
/ decreases expression
mRNA 17891453
C012589 2729 GCLC
GCL
GCS
GLCL
GLCLC
glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) [Fenretinide co-treated with trichostatin A] results in increased expression of GCLC mRNA affects cotreatment
/ increases expression
mRNA 21319187
C012589 2729 GCLC
GCL
GCS
GLCL
GLCLC
glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) trichostatin A results in increased expression of GCLC mRNA increases expression
mRNA 21319187
C012589 8521 GCM1
GCMA
hGCMa
glial cells missing homolog 1 (Drosophila) trichostatin A promotes the reaction [Colforsin results in increased acetylation of and results in increased activity of GCM1 protein] increases acetylation
/ increases activity
/ increases reaction
protein 16166624
C012589 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 mRNA] affects expression
/ decreases reaction
mRNA 18801729
C012589 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 protein] affects expression
/ decreases reaction
protein 18801729
C012589 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 decitabine promotes the reaction [[trichostatin A affects the methylation of GDF15 promoter] which affects the expression of GDF15 mRNA] affects expression
/ affects methylation
/ increases reaction
mRNA / promoter 18801729
C012589 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 decitabine promotes the reaction [[trichostatin A affects the methylation of GDF15 promoter] which affects the expression of GDF15 protein] affects expression
/ affects methylation
/ increases reaction
promoter / protein 18801729
C012589 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 EGR1 protein affects the reaction [trichostatin A affects the expression of GDF15 mRNA] affects expression
/ affects reaction
mRNA 18801729
C012589 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 SP1 protein affects the reaction [trichostatin A affects the expression of GDF15 mRNA] affects expression
/ affects reaction
mRNA 18801729
C012589 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 [trichostatin A results in increased expression of GDF15 protein] which results in increased cleavage of PARP1 protein increases cleavage
/ increases expression
protein 18801729
C012589 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 [trichostatin A results in increased stability of GDF15 mRNA] which results in increased expression of GDF15 protein increases expression
/ increases stability
mRNA / protein 18801729
C012589 2669 GEM
KIR
GTP binding protein overexpressed in skeletal muscle trichostatin A inhibits the reaction [Nickel affects the expression of GEM mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 2798 GNRHR
GNRHR1
GRHR
HH7
LHRHR
LRHR
gonadotropin-releasing hormone receptor trichostatin A inhibits the reaction [Nickel affects the expression of GNRHR mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 2878 GPX3
GPx-P
GSHPx-3
GSHPx-P
glutathione peroxidase 3 (plasma) (EC:1.11.1.9) trichostatin A promotes the reaction [[decitabine affects the methylation of GPX3 promoter] which affects the expression of GPX3 protein] affects expression
/ affects methylation
/ increases reaction
promoter / protein 18664505
C012589 2882 GPX7
CL683
GPX6
GPx-7
GSHPx-7
NPGPx
glutathione peroxidase 7 (EC:1.11.1.9) trichostatin A promotes the reaction [[decitabine affects the methylation of GPX7 promoter] which affects the expression of GPX7 protein] affects expression
/ affects methylation
/ increases reaction
promoter / protein 18664505
C012589 2891 GRIA2
GLUR2
GLURB
GluA2
GluR-K2
HBGR2
glutamate receptor, ionotropic, AMPA 2 trichostatin A inhibits the reaction [Nickel affects the expression of GRIA2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 2946 GSTM2
GST4
GSTM
GSTM2-2
GTHMUS
glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18) trichostatin A affects the expression of GSTM2 mRNA affects expression
mRNA 18664505
C012589 2946 GSTM2
GST4
GSTM
GSTM2-2
GTHMUS
glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18) trichostatin A promotes the reaction [[decitabine affects the methylation of GSTM2 promoter] which affects the expression of GSTM2 protein] affects expression
/ affects methylation
/ increases reaction
promoter / protein 18664505
C012589 2947 GSTM3
GST5
GSTB
GSTM3-3
GTM3
glutathione S-transferase mu 3 (brain) (EC:2.5.1.18) trichostatin A inhibits the reaction [Nickel affects the expression of GSTM3 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) [decitabine co-treated with trichostatin A] results in increased expression of GSTP1 mRNA affects cotreatment
/ increases expression
mRNA 17891453
C012589 2950 GSTP1
DFN7
FAEES3
GST3
GSTP
PI
glutathione S-transferase pi 1 (EC:2.5.1.18) trichostatin A affects the expression of GSTP1 protein affects expression
protein 19294695
C012589 54676 GTPBP2
GTP binding protein 2 [decitabine co-treated with trichostatin A] results in increased expression of GTPBP2 mRNA affects cotreatment
/ increases expression
mRNA 20678512
C012589 54676 GTPBP2
GTP binding protein 2 trichostatin A results in increased expression of GTPBP2 mRNA increases expression
mRNA 20678512
C012589 3005 H1F0
H10
H1FV
H1 histone family, member 0 trichostatin A results in increased expression of H1F0 mRNA increases expression
mRNA 19606018
C012589 15043 trichostatin A inhibits the reaction [Nickel affects the expression of H2-T3 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3065 HDAC1
GON-10
HD1
RPD3
RPD3L1
histone deacetylase 1 (EC:3.5.1.98) trichostatin A results in decreased activity of HDAC1 protein decreases activity
protein 15103026
15927959
15930892
C012589 3065 HDAC1
GON-10
HD1
RPD3
RPD3L1
histone deacetylase 1 (EC:3.5.1.98) trichostatin A results in decreased expression of HDAC1 protein decreases expression
protein 23285096
C012589 3066 HDAC2
HD2
RPD3
YAF1
histone deacetylase 2 (EC:3.5.1.98) trichostatin A results in decreased activity of HDAC2 protein decreases activity
protein 15103026
18421014
C012589 8841 HDAC3
HD3
RPD3
RPD3-2
histone deacetylase 3 (EC:3.5.1.98) trichostatin A results in decreased activity of HDAC3 protein decreases activity
protein 15103026
15930892
C012589 8841 HDAC3
HD3
RPD3
RPD3-2
histone deacetylase 3 (EC:3.5.1.98) trichostatin A results in decreased expression of HDAC3 protein decreases expression
protein 18676679
C012589 10013 HDAC6
CPBHM
HD6
histone deacetylase 6 (EC:3.5.1.98) trichostatin A results in decreased activity of HDAC6 protein decreases activity
protein 15930892
C012589 3087 HHEX
HEX
HMPH
HOX11L-PEN
PRH
PRHX
hematopoietically expressed homeobox trichostatin A results in increased expression of and affects the localization of HHEX protein affects localization
/ increases expression
protein 16854221
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [[3-deazaneplanocin co-treated with trichostatin A] affects the acetylation of and affects the methylation of HIST3H3 protein] which affects the expression of DACT3 affects acetylation
/ affects cotreatment
/ affects expression
/ affects methylation
protein 18538736
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [decitabine co-treated with trichostatin A] affects the acetylation of HIST3H3 protein affects acetylation
/ affects cotreatment
protein 18069755
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [[decitabine co-treated with trichostatin A] affects the acetylation of HIST3H3 protein] which affects the expression of CDH1 mRNA affects acetylation
/ affects cotreatment
/ affects expression
protein 18584348
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [decitabine co-treated with trichostatin A] affects the methylation of HIST3H3 protein affects cotreatment
/ affects methylation
protein 15959780
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [decitabine co-treated with trichostatin A] affects the reaction [HIST3H3 protein modified form binds to RARB gene] affects binding
/ affects cotreatment
/ affects reaction
protein 15959780
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [decitabine co-treated with trichostatin A co-treated with Tretinoin] affects the methylation of HIST3H3 protein affects cotreatment
/ affects methylation
protein 15959780
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [decitabine co-treated with trichostatin A co-treated with Tretinoin] affects the reaction [HIST3H3 protein modified form binds to RARB promoter] affects binding
/ affects cotreatment
/ affects reaction
protein 15959780
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [decitabine co-treated with trichostatin A] results in decreased methylation of HIST3H3 protein affects cotreatment
/ decreases methylation
protein 18291368
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [trichostatin A affects the acetylation of HIST3H3 promoter] which affects the expression of IGFBP3 mRNA affects acetylation
/ affects expression
promoter 16505122
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [trichostatin A affects the acetylation of HIST3H3 protein] which affects the expression of CDH1 mRNA affects acetylation
/ affects expression
protein 18584348
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 trichostatin A promotes the reaction [HIST3H3 protein modified form binds to CCNA1 promoter] affects binding
/ increases reaction
protein 17698632
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 trichostatin A promotes the reaction [HIST3H3 protein modified form binds to PTEN promoter] affects binding
/ increases reaction
protein 17330857
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 trichostatin A promotes the reaction [HIST3H3 protein modified form binds to RARB gene] affects binding
/ increases reaction
protein 15959780
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 trichostatin A results in decreased methylation of HIST3H3 protein decreases methylation
protein 18291368
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 trichostatin A results in increased acetylation of HIST3H3 increases acetylation
18676679
C012589 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 trichostatin A results in increased acetylation of HIST3H3 protein increases acetylation
protein 15959780
16740727
17330857
17431121
17502362
19503093
C012589 121504 HIST4H4
H4/p
histone cluster 4, H4 [[3-deazaneplanocin co-treated with trichostatin A] affects the acetylation of and affects the methylation of HIST4H4 protein] which affects the expression of DACT3 affects acetylation
/ affects cotreatment
/ affects expression
/ affects methylation
protein 18538736
C012589 121504 HIST4H4
H4/p
histone cluster 4, H4 [trichostatin A co-treated with Dexamethasone] inhibits the reaction [IL1B protein promotes the reaction [HIST4H4 protein modified form binds to CSF2 promoter]] affects binding
/ affects cotreatment
/ decreases reaction
/ increases reaction
protein 12070353
C012589 121504 HIST4H4
H4/p
histone cluster 4, H4 trichostatin A promotes the reaction [HIST4H4 protein modified form binds to CCNA1 promoter] affects binding
/ increases reaction
protein 17698632
C012589 121504 HIST4H4
H4/p
histone cluster 4, H4 trichostatin A promotes the reaction [HIST4H4 protein modified form binds to PTEN promoter] affects binding
/ increases reaction
protein 17330857
C012589 121504 HIST4H4
H4/p
histone cluster 4, H4 trichostatin A results in increased acetylation of HIST4H4 protein increases acetylation
protein 16009488
16740727
17330857
19503093
C012589 3141 HLCS
HCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) (EC:6.3.4.10 6.3.4.11 6.3.4.15 6.3.4.9) trichostatin A inhibits the reaction [chromium hexavalent ion results in increased expression of HLCS protein] decreases reaction
/ increases expression
protein 21641978
C012589 23526 HMHA1
ARHGAP45
HA-1
HLA-HA1
histocompatibility (minor) HA-1 trichostatin A results in increased expression of HMHA1 mRNA increases expression
mRNA 19096014
C012589 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) trichostatin A promotes the reaction [Fenretinide results in increased expression of HMOX1 mRNA] increases expression
/ increases reaction
mRNA 21319187
C012589 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) trichostatin A results in increased expression of HMOX1 mRNA increases expression
mRNA 21319187
C012589 3166 HMX1
H6
NKX5-3
H6 family homeobox 1 trichostatin A inhibits the reaction [Nickel affects the expression of HMX1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 6928 HNF1B
FJHN
HNF-1B
HNF1beta
HNF2
HPC11
LF-B3
LFB3
MODY5
TCF-2
TCF2
VHNF1
HNF1 homeobox B trichostatin A inhibits the reaction [Nickel affects the expression of HNF1B mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3181 HNRNPA2B1
HNRNPA2
HNRNPB1
HNRPA2
HNRPA2B1
HNRPB1
IBMPFD2
RNPA2
SNRPB1
heterogeneous nuclear ribonucleoprotein A2/B1 trichostatin A results in decreased expression of HNRNPA2B1 protein decreases expression
protein 19294695
C012589 3202 HOXA5
HOX1
HOX1.3
HOX1C
homeobox A5 [decitabine co-treated with trichostatin A] results in increased expression of HOXA5 mRNA affects cotreatment
/ increases expression
mRNA 17891453
C012589 3214 HOXB4
HOX-2.6
HOX2
HOX2F
homeobox B4 [decitabine co-treated with trichostatin A] results in increased expression of HOXB4 mRNA affects cotreatment
/ increases expression
mRNA 17185465
C012589 3214 HOXB4
HOX-2.6
HOX2
HOX2F
homeobox B4 [decitabine co-treated with trichostatin A] results in increased expression of HOXB4 protein affects cotreatment
/ increases expression
protein 17185465
C012589 3231 HOXD1
HOX4
HOX4G
Hox-4.7
homeobox D1 trichostatin A inhibits the reaction [Nickel affects the expression of HOXD1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3248 HPGD
15-PGDH
PGDH
PGDH1
PHOAR1
SDR36C1
hydroxyprostaglandin dehydrogenase 15-(NAD) (EC:1.1.1.141) trichostatin A promotes the reaction [Azacitidine results in increased expression of HPGD mRNA] increases expression
/ increases reaction
mRNA 19584167
C012589 3248 HPGD
15-PGDH
PGDH
PGDH1
PHOAR1
SDR36C1
hydroxyprostaglandin dehydrogenase 15-(NAD) (EC:1.1.1.141) trichostatin A results in increased expression of HPGD mRNA increases expression
mRNA 19584167
C012589 3320 HSP90AA1
EL52
HSP86
HSP89A
HSP90A
HSP90N
HSPC1
HSPCA
HSPCAL1
HSPCAL4
HSPN
Hsp89
Hsp90
LAP2
heat shock protein 90kDa alpha (cytosolic), class A member 1 trichostatin A affects the expression of HSP90AA1 protein affects expression
protein 19294695
C012589 3320 HSP90AA1
EL52
HSP86
HSP89A
HSP90A
HSP90N
HSPC1
HSPCA
HSPCAL1
HSPCAL4
HSPN
Hsp89
Hsp90
LAP2
heat shock protein 90kDa alpha (cytosolic), class A member 1 [trichostatin A co-treated with decitabine] results in decreased expression of HSP90AA1 protein affects cotreatment
/ decreases expression
protein 19294695
C012589 3305 HSPA1L
HSP70-1L
HSP70-HOM
HSP70T
hum70t
heat shock 70kDa protein 1-like trichostatin A inhibits the reaction [Nickel affects the expression of HSPA1L mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3313 HSPA9
CSA
GRP-75
GRP75
HSPA9B
MOT
MOT2
MTHSP75
PBP74
heat shock 70kDa protein 9 (mortalin) trichostatin A results in decreased expression of HSPA9 protein decreases expression
protein 19294695
C012589 27429 HTRA2
OMI
PARK13
PRSS25
HtrA serine peptidase 2 (EC:3.4.21.108) [vorinostat co-treated with trichostatin A] affects the localization of HTRA2 protein affects cotreatment
/ affects localization
protein 16026644
C012589 3381 IBSP
BNSP
BSP
BSP-II
SP-II
integrin-binding sialoprotein trichostatin A inhibits the reaction [Nickel affects the expression of IBSP mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3458 IFNG
IFG
IFI
interferon, gamma trichostatin A inhibits the reaction [Nickel affects the expression of IFNG mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 11020 IFT27
RABL4
RAYL
intraflagellar transport 27 homolog (Chlamydomonas) trichostatin A inhibits the reaction [Nickel affects the expression of IFT27 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3486 IGFBP3
BP-53
IBP3
insulin-like growth factor binding protein 3 [trichostatin A affects the acetylation of HIST3H3 promoter] which affects the expression of IGFBP3 mRNA affects acetylation
/ affects expression
mRNA 16505122
C012589 22806 IKZF3
AIO
AIOLOS
ZNFN1A3
IKAROS family zinc finger 3 (Aiolos) trichostatin A affects the expression of IKZF3 mRNA affects expression
mRNA 18206652
C012589 22806 IKZF3
AIO
AIOLOS
ZNFN1A3
IKAROS family zinc finger 3 (Aiolos) trichostatin A affects the expression of IKZF3 protein affects expression
protein 18206652
C012589 22806 IKZF3
AIO
AIOLOS
ZNFN1A3
IKAROS family zinc finger 3 (Aiolos) trichostatin A promotes the reaction [decitabine results in increased expression of IKZF3 mRNA] increases expression
/ increases reaction
mRNA 18206652
C012589 3592 IL12A
CLMF
IL-12A
NFSK
NKSF1
P35
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] decreases reaction
/ increases expression
mRNA 12470611
C012589 3592 IL12A
CLMF
IL-12A
NFSK
NKSF1
P35
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) trichostatin A results in increased expression of IL12A mRNA increases expression
mRNA 12470611
C012589 3593 IL12B
CLMF
CLMF2
IL-12B
NKSF
NKSF2
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] decreases reaction
/ increases expression
mRNA 12470611
C012589 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta [trichostatin A co-treated with Dexamethasone] inhibits the reaction [IL1B protein promotes the reaction [HIST4H4 protein modified form binds to CSF2 promoter]] affects binding
/ affects cotreatment
/ decreases reaction
/ increases reaction
protein 12070353
C012589 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta trichostatin A inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]] decreases reaction
/ increases secretion
protein 12070353
C012589 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta trichostatin A inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein] decreases reaction
/ increases expression
protein 19281832
C012589 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta trichostatin A inhibits the reaction [[Theophylline co-treated with Dexamethasone] inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]] affects cotreatment
/ decreases reaction
/ increases secretion
protein 12070353
C012589 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta trichostatin A promotes the reaction [IL1B protein results in increased expression of TGFB1 mRNA] increases expression
/ increases reaction
protein 16365456
C012589 54450 trichostatin A inhibits the reaction [Nickel affects the expression of IL1F5 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3559 IL2RA
CD25
IDDM10
IL2R
TCGFR
interleukin 2 receptor, alpha trichostatin A inhibits the reaction [Nickel affects the expression of IL2RA mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3572 IL6ST
CD130
CDW130
GP130
IL-6RB
interleukin 6 signal transducer (gp130, oncostatin M receptor) trichostatin A results in increased expression of IL6ST mRNA increases expression
mRNA 19223499
C012589 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 trichostatin A promotes the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL8 protein] increases expression
/ increases reaction
/ increases secretion
protein 12470611
C012589 3619 INCENP
inner centromere protein antigens 135/155kDa trichostatin A results in decreased expression of INCENP mRNA decreases expression
mRNA 19606018
C012589 3625 INHBB
inhibin, beta B trichostatin A inhibits the reaction [Nickel affects the expression of INHBB mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3394 IRF8
H-ICSBP
ICSBP
ICSBP1
IRF-8
interferon regulatory factor 8 trichostatin A affects the reaction [[decitabine affects the methylation of IRF8 promoter] which affects the expression of IRF8 protein] affects expression
/ affects methylation
/ affects reaction
promoter / protein 18922617
C012589 3683 ITGAL
CD11A
LFA-1
LFA1A
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) trichostatin A inhibits the reaction [Nickel affects the expression of ITGAL mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3684 ITGAM
CD11B
CR3A
MAC-1
MAC1A
MO1A
SLEB6
integrin, alpha M (complement component 3 receptor 3 subunit) decitabine promotes the reaction [trichostatin A results in increased expression of ITGAM mRNA] increases expression
/ increases reaction
mRNA 18718068
C012589 3684 ITGAM
CD11B
CR3A
MAC-1
MAC1A
MO1A
SLEB6
integrin, alpha M (complement component 3 receptor 3 subunit) trichostatin A results in increased expression of ITGAM mRNA increases expression
mRNA 18718068
C012589 3714 JAG2
HJ2
SER2
jagged 2 trichostatin A inhibits the reaction [Nickel affects the expression of JAG2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3717 JAK2
JTK10
THCYT3
Janus kinase 2 (EC:2.7.10.2) trichostatin A inhibits the reaction [Nickel affects the expression of JAK2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JUN protein]] decreases reaction
/ increases phosphorylation
protein 21911040
C012589 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of JUN protein] decreases reaction
/ increases phosphorylation
protein 21911040
C012589 3726 JUNB
AP-1
jun B proto-oncogene trichostatin A affects the expression of JUNB mRNA affects expression
mRNA 16505122
C012589 3778 KCNMA1
BKTM
KCa1.1
MaxiK
SAKCA
SLO
SLO-ALPHA
SLO1
bA205K10.1
mSLO1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1 trichostatin A inhibits the reaction [Nickel affects the expression of KCNMA1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 9682 KDM4A
JHDM3A
JMJD2
JMJD2A
TDRD14A
lysine (K)-specific demethylase 4A (EC:1.14.11.-) trichostatin A results in decreased activity of KDM4A protein decreases activity
protein 15927959
C012589 9682 KDM4A
JHDM3A
JMJD2
JMJD2A
TDRD14A
lysine (K)-specific demethylase 4A (EC:1.14.11.-) trichostatin A results in decreased expression of KDM4A mRNA decreases expression
mRNA 15927959
C012589 9682 KDM4A
JHDM3A
JMJD2
JMJD2A
TDRD14A
lysine (K)-specific demethylase 4A (EC:1.14.11.-) trichostatin A results in increased expression of KDM4A mRNA increases expression
mRNA 15927959
C012589 23030 KDM4B
JMJD2B
TDRD14B
lysine (K)-specific demethylase 4B trichostatin A results in increased expression of KDM4B mRNA increases expression
mRNA 15927959
C012589 688 KLF5
BTEB2
CKLF
IKLF
Kruppel-like factor 5 (intestinal) [decitabine co-treated with trichostatin A] results in increased expression of KLF5 mRNA affects cotreatment
/ increases expression
mRNA 20678512
C012589 688 KLF5
BTEB2
CKLF
IKLF
Kruppel-like factor 5 (intestinal) trichostatin A results in increased expression of KLF5 mRNA increases expression
mRNA 20678512
C012589 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) [trichostatin A co-treated with decitabine] results in increased expression of KLK3 mRNA affects cotreatment
/ increases expression
mRNA 18092350
C012589 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) trichostatin A inhibits the reaction [Curcumin results in decreased expression of KLK3 mRNA] decreases expression
/ decreases reaction
mRNA 22258452
C012589 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) trichostatin A results in decreased expression of KLK3 mRNA decreases expression
mRNA 19805354
C012589 16638 trichostatin A results in increased expression of KLRA7 mRNA increases expression
mRNA 16750269
C012589 10219 KLRG1
2F1
CLEC15A
MAFA
MAFA-2F1
MAFA-L
MAFA-LIKE
killer cell lectin-like receptor subfamily G, member 1 trichostatin A inhibits the reaction [Nickel affects the expression of KLRG1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3837 KPNB1
IMB1
IPO1
IPOB
Impnb
NTF97
karyopherin (importin) beta 1 trichostatin A results in decreased expression of KPNB1 mRNA decreases expression
mRNA 19606018
C012589 3858 KRT10
BCIE
BIE
CK10
EHK
K10
KPP
keratin 10 trichostatin A inhibits the reaction [Nickel affects the expression of KRT10 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 3856 KRT8
CARD2
CK-8
CK8
CYK8
K2C8
K8
KO
keratin 8 trichostatin A affects the expression of KRT8 protein affects expression
protein 19294695
C012589 3856 KRT8
CARD2
CK-8
CK8
CYK8
K2C8
K8
KO
keratin 8 [trichostatin A co-treated with decitabine] results in decreased expression of KRT8 protein affects cotreatment
/ decreases expression
protein 19294695
C012589 27074 LAMP3
CD208
DC_LAMP
DC-LAMP
DCLAMP
LAMP
LAMP-3
TSC403
lysosomal-associated membrane protein 3 [decitabine co-treated with trichostatin A] results in increased expression of LAMP3 mRNA affects cotreatment
/ increases expression
mRNA 20678512
C012589 27074 LAMP3
CD208
DC_LAMP
DC-LAMP
DCLAMP
LAMP
LAMP-3
TSC403
lysosomal-associated membrane protein 3 Estradiol inhibits the reaction [[decitabine co-treated with trichostatin A] results in increased expression of LAMP3 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 20678512
C012589 27074 LAMP3
CD208
DC_LAMP
DC-LAMP
DCLAMP
LAMP
LAMP-3
TSC403
lysosomal-associated membrane protein 3 Estradiol inhibits the reaction [trichostatin A results in increased expression of LAMP3 mRNA] decreases reaction
/ increases expression
mRNA 20678512
C012589 27074 LAMP3
CD208
DC_LAMP
DC-LAMP
DCLAMP
LAMP
LAMP-3
TSC403
lysosomal-associated membrane protein 3 trichostatin A results in increased expression of LAMP3 mRNA increases expression
mRNA 20678512
C012589 51176 LEF1
LEF-1
TCF10
TCF1ALPHA
TCF7L3
lymphoid enhancer-binding factor 1 [3-deazaneplanocin co-treated with trichostatin A] affects the expression of LEF1 protein affects cotreatment
/ affects expression
protein 18538736
C012589 51176 LEF1
LEF-1
TCF10
TCF1ALPHA
TCF7L3
lymphoid enhancer-binding factor 1 trichostatin A inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]] affects binding
/ decreases reaction
/ increases reaction
protein 22552774
C012589 51176 LEF1
LEF-1
TCF10
TCF1ALPHA
TCF7L3
lymphoid enhancer-binding factor 1 trichostatin A inhibits the reaction [Dibutyl Phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]] affects binding
/ decreases reaction
/ increases reaction
protein 22552774
C012589 3952 LEP
LEPD
OB
OBS
leptin trichostatin A promotes the reaction [decitabine results in increased expression of LEP mRNA] increases expression
/ increases reaction
mRNA 17502362
C012589 3952 LEP
LEPD
OB
OBS
leptin trichostatin A results in increased expression of LEP mRNA increases expression
mRNA 17502362
C012589 3954 LETM1
leucine zipper-EF-hand containing transmembrane protein 1 [decitabine co-treated with trichostatin A] results in decreased expression of LETM1 mRNA affects cotreatment
/ decreases expression
mRNA 17891453
C012589 3988 LIPA
CESD
LAL
lipase A, lysosomal acid, cholesterol esterase (EC:3.1.1.13) trichostatin A inhibits the reaction [Nickel affects the expression of LIPA mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4017 LOXL2
LOR2
WS9-14
lysyl oxidase-like 2 (EC:1.4.3.-) trichostatin A promotes the reaction [decitabine results in increased expression of LOXL2 mRNA] increases expression
/ increases reaction
mRNA 19330836
C012589 116135 LRRC3B
LRP15
leucine rich repeat containing 3B [[decitabine co-treated with trichostatin A] affects the methylation of LRRC3B promoter] which affects the expression of LRRC3B mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18757430
C012589 23639 LRRC6
CILD19
LRTP
TSLRP
leucine rich repeat containing 6 trichostatin A inhibits the reaction [Nickel affects the expression of LRRC6 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 110454 trichostatin A inhibits the reaction [Nickel affects the expression of LY6A mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4069 LYZ
LZM
lysozyme (EC:3.2.1.17) trichostatin A results in increased expression of LYZ mRNA increases expression
mRNA 17000900
C012589 9935 MAFB
KRML
MCTO
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B trichostatin A inhibits the reaction [Nickel affects the expression of MAFB mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 81631 MAP1LC3B
ATG8F
LC3B
MAP1A/1BLC3
MAP1LC3B-a
microtubule-associated protein 1 light chain 3 beta trichostatin A affects the localization of MAP1LC3B protein modified form affects localization
protein 20543569
C012589 81631 MAP1LC3B
ATG8F
LC3B
MAP1A/1BLC3
MAP1LC3B-a
microtubule-associated protein 1 light chain 3 beta trichostatin A results in increased cleavage of MAP1LC3B protein increases cleavage
protein 20543569
C012589 81631 MAP1LC3B
ATG8F
LC3B
MAP1A/1BLC3
MAP1LC3B-a
microtubule-associated protein 1 light chain 3 beta trichostatin A results in increased expression of MAP1LC3B mRNA increases expression
mRNA 19606018
C012589 81631 MAP1LC3B
ATG8F
LC3B
MAP1A/1BLC3
MAP1LC3B-a
microtubule-associated protein 1 light chain 3 beta trichostatin A results in increased expression of MAP1LC3B protein modified form increases expression
protein 20962572
C012589 5604 MAP2K1
CFC3
MAPKK1
MEK1
MKK1
PRKMK1
mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) MAP2K1 protein mutant form results in decreased activity of [perifosine co-treated with trichostatin A] affects cotreatment
/ decreases activity
protein 15781658
C012589 5871 MAP4K2
BL44
GCK
RAB8IP
mitogen-activated protein kinase kinase kinase kinase 2 (EC:2.7.11.1) trichostatin A inhibits the reaction [Nickel affects the expression of MAP4K2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) [perifosine co-treated with trichostatin A] results in decreased activity of MAPK1 protein affects cotreatment
/ decreases activity
protein 15781658
C012589 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) trichostatin A results in decreased activity of MAPK1 protein decreases activity
protein 15179185
C012589 1432 MAPK14
CSBP
CSBP1
CSBP2
CSPB1
EXIP
Mxi2
PRKM14
PRKM15
RK
SAPK2A
p38
p38ALPHA
mitogen-activated protein kinase 14 (EC:2.7.11.24) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]] decreases reaction
/ increases phosphorylation
protein 21911040
C012589 1432 MAPK14
CSBP
CSBP1
CSBP2
CSPB1
EXIP
Mxi2
PRKM14
PRKM15
RK
SAPK2A
p38
p38ALPHA
mitogen-activated protein kinase 14 (EC:2.7.11.24) trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein] decreases reaction
/ increases phosphorylation
protein 21911040
C012589 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) [perifosine co-treated with trichostatin A] results in decreased activity of MAPK3 protein affects cotreatment
/ decreases activity
protein 15781658
C012589 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) trichostatin A results in decreased activity of MAPK3 protein decreases activity
protein 15179185
C012589 5599 MAPK8
JNK
JNK-46
JNK1
JNK1A2
JNK21B1/2
PRKM8
SAPK1
SAPK1c
mitogen-activated protein kinase 8 (EC:2.7.11.24) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]] decreases reaction
/ increases phosphorylation
protein 21911040
C012589 5599 MAPK8
JNK
JNK-46
JNK1
JNK1A2
JNK21B1/2
PRKM8
SAPK1
SAPK1c
mitogen-activated protein kinase 8 (EC:2.7.11.24) [perifosine co-treated with trichostatin A] results in increased activity of MAPK8 protein affects cotreatment
/ increases activity
protein 15781658
C012589 5599 MAPK8
JNK
JNK-46
JNK1
JNK1A2
JNK21B1/2
PRKM8
SAPK1
SAPK1c
mitogen-activated protein kinase 8 (EC:2.7.11.24) trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] decreases reaction
/ increases phosphorylation
protein 21911040
C012589 5601 MAPK9
JNK-55
JNK2
JNK2A
JNK2ALPHA
JNK2B
JNK2BETA
PRKM9
SAPK
SAPK1a
p54a
p54aSAPK
mitogen-activated protein kinase 9 (EC:2.7.11.24) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]] decreases reaction
/ increases phosphorylation
protein 21911040
C012589 5601 MAPK9
JNK-55
JNK2
JNK2A
JNK2ALPHA
JNK2B
JNK2BETA
PRKM9
SAPK
SAPK1a
p54a
p54aSAPK
mitogen-activated protein kinase 9 (EC:2.7.11.24) trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein] decreases reaction
/ increases phosphorylation
protein 21911040
C012589 4139 MARK1
MARK
Par-1c
Par1c
MAP/microtubule affinity-regulating kinase 1 (EC:2.7.11.1 2.7.11.26) trichostatin A inhibits the reaction [Nickel affects the expression of MARK1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 8932 MBD2
DMTase
NY-CO-41
methyl-CpG binding domain protein 2 [decitabine co-treated with trichostatin A] inhibits the reaction [MBD2 protein binds to CLDN3 promoter] affects binding
/ affects cotreatment
/ decreases reaction
protein 17986852
C012589 55777 MBD5
MRD1
methyl-CpG binding domain protein 5 [decitabine co-treated with trichostatin A] results in decreased expression of MBD5 mRNA affects cotreatment
/ decreases expression
mRNA 17891453
C012589 4170 MCL1
BCL2L3
EAT
MCL1-ES
MCL1L
MCL1S
Mcl-1
TM
bcl2-L-3
mcl1/EAT
myeloid cell leukemia sequence 1 (BCL2-related) trichostatin A results in decreased expression of MCL1 protein decreases expression
protein 16009488
C012589 4172 MCM3
HCC5
P1-MCM3
P1.h
RLFB
minichromosome maintenance complex component 3 (EC:3.6.4.12) trichostatin A results in decreased expression of MCM3 mRNA decreases expression
mRNA 19606018
C012589 4176 MCM7
CDC47
MCM2
P1.1-MCM3
P1CDC47
P85MCM
PNAS146
minichromosome maintenance complex component 7 (EC:3.6.4.12) trichostatin A inhibits the reaction [Nickel affects the expression of MCM7 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4204 MECP2
AUTSX3
MRX16
MRX79
MRXS13
MRXSL
PPMX
RS
RTS
RTT
methyl CpG binding protein 2 (Rett syndrome) [decitabine co-treated with trichostatin A] results in decreased expression of MECP2 mRNA affects cotreatment
/ decreases expression
mRNA 17891453
C012589 4204 MECP2
AUTSX3
MRX16
MRX79
MRXS13
MRXSL
PPMX
RS
RTS
RTT
methyl CpG binding protein 2 (Rett syndrome) trichostatin A inhibits the reaction [MECP2 protein binds to CCNA1 promoter] affects binding
/ decreases reaction
protein 17698632
C012589 4205 MEF2A
ADCAD1
RSRFC4
RSRFC9
mef2
myocyte enhancer factor 2A trichostatin A inhibits the reaction [Nickel affects the expression of MEF2A mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4255 MGMT
O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) [decitabine co-treated with trichostatin A] results in increased expression of MGMT mRNA affects cotreatment
/ increases expression
mRNA 15657354
C012589 4256 MGP
MGLAP
NTI
matrix Gla protein trichostatin A inhibits the reaction [Nickel affects the expression of MGP mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4292 MLH1
COCA2
FCC2
HNPCC
HNPCC2
hMLH1
mutL homolog 1 [decitabine co-treated with trichostatin A] affects the methylation of MLH1 promoter affects cotreatment
/ affects methylation
promoter 18069755
C012589 4321 MMP12
HME
ME
MME
MMP-12
matrix metallopeptidase 12 (macrophage elastase) (EC:3.4.24.65) trichostatin A inhibits the reaction [Nickel affects the expression of MMP12 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4322 MMP13
CLG3
MANDP1
matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-) [decitabine co-treated with trichostatin A] results in increased expression of MMP13 mRNA affects cotreatment
/ increases expression
mRNA 17891453
C012589 4353 MPO
myeloperoxidase (EC:1.11.2.2) [decitabine co-treated with trichostatin A] results in increased expression of MPO mRNA affects cotreatment
/ increases expression
mRNA 17185465
C012589 2206 MS4A2
APY
ATOPY
FCER1B
FCERI
IGEL
IGER
IGHER
MS4A1
membrane-spanning 4-domains, subfamily A, member 2 trichostatin A inhibits the reaction [Nickel affects the expression of MS4A2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4547 MTTP
ABL
MTP
microsomal triglyceride transfer protein trichostatin A inhibits the reaction [Nickel affects the expression of MTTP mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4585 MUC4
ASGP
HSA276359
MUC-4
mucin 4, cell surface associated [decitabine co-treated with trichostatin A] results in increased expression of MUC4 mRNA affects cotreatment
/ increases expression
mRNA 19127263
C012589 4585 MUC4
ASGP
HSA276359
MUC-4
mucin 4, cell surface associated trichostatin A results in increased expression of MUC4 mRNA increases expression
mRNA 19127263
C012589 4599 MX1
IFI-78K
IFI78
MX
MxA
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) trichostatin A inhibits the reaction [Nickel affects the expression of MX1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog [3-deazaneplanocin co-treated with trichostatin A] affects the expression of MYC protein affects cotreatment
/ affects expression
protein 18538736
C012589 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog [decitabine co-treated with trichostatin A] results in increased expression of MYC mRNA affects cotreatment
/ increases expression
mRNA 17185465
C012589 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog trichostatin A results in decreased expression of MYC mRNA decreases expression
mRNA 12414619
C012589 4621 MYH3
HEMHC
MYHC-EMB
MYHSE1
SMHCE
myosin, heavy chain 3, skeletal muscle, embryonic trichostatin A inhibits the reaction [Nickel affects the expression of MYH3 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 23040 MYT1L
NZF1
ZC2HC4B
myelin transcription factor 1-like trichostatin A inhibits the reaction [Nickel affects the expression of MYT1L mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4666 NACA
NACA1
nascent polypeptide-associated complex alpha subunit (EC:5.3.99.3) trichostatin A inhibits the reaction [Nickel affects the expression of NACA mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4690 NCK1
NCK
NCKalpha
nck-1
NCK adaptor protein 1 [decitabine co-treated with trichostatin A] results in increased expression of NCK1 mRNA affects cotreatment
/ increases expression
mRNA 20678512
C012589 8031 NCOA4
ARA70
ELE1
PTC3
RFG
nuclear receptor coactivator 4 trichostatin A inhibits the reaction [Nickel affects the expression of NCOA4 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 9437 NCR1
CD335
LY94
NK-p46
NKP46
natural cytotoxicity triggering receptor 1 trichostatin A inhibits the reaction [Nickel affects the expression of NCR1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4712 NDUFB6
B17
CI
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa (EC:1.6.5.3 1.6.99.3) trichostatin A inhibits the reaction [Nickel affects the expression of NDUFB6 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4718 NDUFC2
B14.5b
CI-B14.5b
HLC-1
NADHDH2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa trichostatin A inhibits the reaction [Nickel affects the expression of NDUFC2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4792 NFKBIA
IKBA
MAD-3
NFKBI
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha trichostatin A results in increased expression of NFKBIA mRNA increases expression
mRNA 15899819
C012589 23420 NOMO1
Nomo
PM5
NODAL modulator 1 trichostatin A inhibits the reaction [Nickel affects the expression of NOMO1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 4851 NOTCH1
TAN1
hN1
notch 1 [decitabine co-treated with trichostatin A] results in decreased expression of NOTCH1 mRNA affects cotreatment
/ decreases expression
mRNA 17185465
C012589 4881 NPR1
ANPRA
ANPa
GUC2A
GUCY2A
NPRA
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (EC:4.6.1.2) trichostatin A inhibits the reaction [Nickel affects the expression of NPR1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) [Fenretinide co-treated with trichostatin A] results in decreased expression of NQO1 mRNA affects cotreatment
/ decreases expression
mRNA 21319187
C012589 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) trichostatin A results in decreased expression of NQO1 mRNA decreases expression
mRNA 21319187
C012589 2908 NR3C1
GCCR
GCR
GR
GRL
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) trichostatin A results in decreased expression of NR3C1 mRNA alternative form decreases expression
mRNA 17498915
C012589 2908 NR3C1
GCCR
GCR
GR
GRL
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) trichostatin A results in decreased expression of NR3C1 protein alternative form decreases expression
protein 17498915
C012589 2908 NR3C1
GCCR
GCR
GR
GRL
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) trichostatin A results in increased expression of NR3C1 mRNA alternative form increases expression
mRNA 17498915
C012589 2908 NR3C1
GCCR
GCR
GR
GRL
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) trichostatin A results in increased expression of NR3C1 protein alternative form increases expression
protein 17498915
C012589 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 [Fenretinide co-treated with trichostatin A] affects the localization of NR4A1 protein affects cotreatment
/ affects localization
protein 21319187
C012589 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 Fenretinide promotes the reaction [trichostatin A results in increased expression of NR4A1 mRNA] increases expression
/ increases reaction
mRNA 21319187
C012589 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 Fenretinide promotes the reaction [trichostatin A results in increased expression of NR4A1 protein] increases expression
/ increases reaction
protein 21319187
C012589 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 NR4A1 protein promotes the reaction [trichostatin A results in increased cleavage of CASP3 protein] increases cleavage
/ increases reaction
protein 21319187
C012589 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 RARB protein promotes the reaction [Fenretinide promotes the reaction [trichostatin A results in increased expression of NR4A1 protein]] increases expression
/ increases reaction
protein 21319187
C012589 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 RARB protein promotes the reaction [trichostatin A results in increased expression of NR4A1 protein] increases expression
/ increases reaction
protein 21319187
C012589 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 trichostatin A affects the localization of NR4A1 protein affects localization
protein 21319187
C012589 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 trichostatin A promotes the reaction [Fenretinide results in increased expression of NR4A1 mRNA] increases expression
/ increases reaction
mRNA 21319187
C012589 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 trichostatin A results in increased expression of NR4A1 mRNA increases expression
mRNA 21319187
C012589 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 trichostatin A results in increased expression of NR4A1 protein increases expression
protein 21319187
C012589 8829 NRP1
BDCA4
CD304
NP1
NRP
VEGF165R
neuropilin 1 trichostatin A results in increased expression of NRP1 mRNA increases expression
mRNA 16330548
C012589 8829 NRP1
BDCA4
CD304
NP1
NRP
VEGF165R
neuropilin 1 trichostatin A results in increased expression of NRP1 protein increases expression
protein 16330548
C012589 100506658 OCLN
BLCPMG
occludin (EC:2.1.1.67) trichostatin A results in increased expression of OCLN mRNA increases expression
mRNA 18661270
C012589 4953 ODC1
ODC
ornithine decarboxylase 1 (EC:4.1.1.17) trichostatin A results in increased expression of ODC1 mRNA increases expression
mRNA 19606018
C012589 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) [bortezomib co-treated with trichostatin A] results in increased cleavage of and results in increased activity of PARP1 protein affects cotreatment
/ increases activity
/ increases cleavage
protein 16904634
C012589 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) trichostatin A inhibits the reaction [Benzene results in decreased expression of PARP1 mRNA] decreases expression
/ decreases reaction
mRNA 20230882
C012589 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) trichostatin A inhibits the reaction [Benzene results in increased methylation of PARP1 promoter] decreases reaction
/ increases methylation
promoter 20230882
C012589 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) trichostatin A results in increased cleavage of PARP1 protein increases cleavage
protein 17431121
C012589 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) trichostatin A results in increased degradation of PARP1 protein increases degradation
protein 16010430
C012589 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) [trichostatin A results in increased expression of GDF15 protein] which results in increased cleavage of PARP1 protein increases cleavage
/ increases expression
protein 18801729
C012589 301164 trichostatin A affects the localization of PCAF protein affects localization
protein 15647279
C012589 301164 trichostatin A promotes the reaction [PCAF protein binds to TGFBR2 promoter] affects binding
/ increases reaction
protein 15647279
C012589 57526 PCDH19
EFMR
EIEE9
protocadherin 19 [decitabine co-treated with trichostatin A] results in increased expression of PCDH19 mRNA affects cotreatment
/ increases expression
mRNA 17891453
C012589 5166 PDK4
pyruvate dehydrogenase kinase, isozyme 4 (EC:2.7.11.2) trichostatin A promotes the reaction [CREBBP protein binds to PDK4 promoter] affects binding
/ increases reaction
promoter 16757381
C012589 5166 PDK4
pyruvate dehydrogenase kinase, isozyme 4 (EC:2.7.11.2) trichostatin A promotes the reaction [SP1 protein binds to PDK4 promoter] affects binding
/ increases reaction
promoter 16757381
C012589 5166 PDK4
pyruvate dehydrogenase kinase, isozyme 4 (EC:2.7.11.2) trichostatin A results in increased expression of PDK4 mRNA increases expression
mRNA 16757381
C012589 57162 PELI1
pellino E3 ubiquitin protein ligase 1 [decitabine co-treated with trichostatin A] results in increased expression of PELI1 mRNA affects cotreatment
/ increases expression
mRNA 20678512
C012589 57162 PELI1
pellino E3 ubiquitin protein ligase 1 trichostatin A results in increased expression of PELI1 mRNA increases expression
mRNA 20678512
C012589 18630 trichostatin A inhibits the reaction [Nickel affects the expression of PET2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 5241 PGR
NR3C3
PR
progesterone receptor [decitabine co-treated with trichostatin A] affects the expression of PGR mRNA affects cotreatment
/ affects expression
mRNA 18264725
C012589 5241 PGR
NR3C3
PR
progesterone receptor [decitabine co-treated with trichostatin A] results in increased expression of PGR mRNA affects cotreatment
/ increases expression
mRNA 17533736
C012589 5241 PGR
NR3C3
PR
progesterone receptor [trichostatin A co-treated with decitabine] results in increased expression of PGR mRNA alternative form affects cotreatment
/ increases expression
mRNA 16024066
C012589 5241 PGR
NR3C3
PR
progesterone receptor [trichostatin A co-treated with decitabine] results in increased expression of PGR protein alternative form affects cotreatment
/ increases expression
protein 16024066
C012589 5241 PGR
NR3C3
PR
progesterone receptor trichostatin A results in increased expression of PGR mRNA alternative form increases expression
mRNA 16024066
C012589 5241 PGR
NR3C3
PR
progesterone receptor trichostatin A results in increased expression of PGR protein alternative form increases expression
protein 16024066
C012589 5293 PIK3CD
P110DELTA
PI3K
p110D
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (EC:2.7.1.153) trichostatin A results in increased expression of PIK3CD mRNA increases expression
mRNA 17940511
C012589 5292 PIM1
PIM
pim-1 oncogene (EC:2.7.11.1) [decitabine co-treated with trichostatin A] results in increased expression of PIM1 mRNA affects cotreatment
/ increases expression
mRNA 20678512
C012589 5292 PIM1
PIM
pim-1 oncogene (EC:2.7.11.1) trichostatin A results in increased expression of PIM1 mRNA increases expression
mRNA 20678512
C012589 51426 POLK
DINB1
DINP
POLQ
polymerase (DNA directed) kappa (EC:2.7.7.7) trichostatin A inhibits the reaction [Nickel affects the expression of POLK mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 5460 POU5F1
OCT3
OCT4
OTF-3
OTF3
OTF4
Oct-3
Oct-4
POU class 5 homeobox 1 trichostatin A promotes the reaction [decitabine affects the expression of POU5F1 mRNA] affects expression
/ increases reaction
mRNA 18440631
C012589 5478 PPIA
CYPA
CYPH
peptidylprolyl isomerase A (cyclophilin A) (EC:5.2.1.8) [trichostatin A co-treated with decitabine] results in decreased expression of PPIA protein affects cotreatment
/ decreases expression
protein 19294695
C012589 81706 PPP1R14C
CPI17-like
KEPI
NY-BR-81
protein phosphatase 1, regulatory (inhibitor) subunit 14C [[decitabine co-treated with trichostatin A] affects the methylation of PPP1R14C promoter] which affects the expression of PPP1R14C mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18803327
C012589 5507 PPP1R3C
PPP1R5
protein phosphatase 1, regulatory subunit 3C [[decitabine co-treated with trichostatin A] affects the methylation of PPP1R3C promoter] which affects the expression of PPP1R3C mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18803327
C012589 5052 PRDX1
MSP23
NKEF-A
NKEFA
PAG
PAGA
PAGB
PRX1
PRXI
TDPX2
peroxiredoxin 1 (EC:1.11.1.15) trichostatin A results in increased expression of PRDX1 protein increases expression
protein 19294695
C012589 5590 PRKCZ
PKC-ZETA
PKC2
protein kinase C, zeta (EC:2.7.11.13) trichostatin A inhibits the reaction [Nickel affects the expression of PRKCZ mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 55015 PRPF39
pre-mRNA processing factor 39 trichostatin A inhibits the reaction [Nickel affects the expression of PRPF39 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 5645 PRSS2
TRY2
TRY8
TRYP2
protease, serine, 2 (trypsin 2) (EC:3.4.21.4) trichostatin A inhibits the reaction [Nickel affects the expression of PRSS2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 5692 PSMB4
HN3
HsN3
PROS-26
PROS26
proteasome (prosome, macropain) subunit, beta type, 4 (EC:3.4.25.1) [trichostatin A co-treated with decitabine] results in decreased expression of PSMB4 protein affects cotreatment
/ decreases expression
protein 19294695
C012589 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) [Doxorubicin co-treated with trichostatin A] results in increased expression of PTEN mRNA affects cotreatment
/ increases expression
mRNA 17330857
C012589 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) PTEN protein affects the susceptibility to [Doxorubicin co-treated with trichostatin A] affects cotreatment
/ affects response to substance
protein 17330857
C012589 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) trichostatin A promotes the reaction [[EP300 protein co-treated with EGR1 protein] results in increased expression of PTEN mRNA] affects cotreatment
/ increases expression
/ increases reaction
mRNA 17330857
C012589 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) trichostatin A promotes the reaction [HIST3H3 protein modified form binds to PTEN promoter] affects binding
/ increases reaction
promoter 17330857
C012589 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) trichostatin A promotes the reaction [HIST4H4 protein modified form binds to PTEN promoter] affects binding
/ increases reaction
promoter 17330857
C012589 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) trichostatin A results in increased expression of PTEN mRNA increases expression
mRNA 17330857
C012589 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) trichostatin A results in increased expression of PTEN protein increases expression
protein 17330857
C012589 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]] decreases reaction
/ increases expression
protein 21911040
C012589 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]] decreases reaction
/ increases chemical synthesis
/ increases expression
protein 21911040
C012589 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) [Tretinoin co-treated with Lipopolysaccharides co-treated with trichostatin A] results in decreased expression of PTGS2 protein affects cotreatment
/ decreases expression
protein 16959971
C012589 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] decreases reaction
/ increases expression
mRNA 21911040
C012589 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] decreases reaction
/ increases expression
protein 21911040
C012589 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) trichostatin A inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone] decreases reaction
/ increases chemical synthesis
/ increases expression
protein 21911040
C012589 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) trichostatin A results in decreased expression of PTGS2 mRNA decreases expression
mRNA 16010430
C012589 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) trichostatin A results in decreased expression of PTGS2 protein decreases expression
protein 16010430
C012589 5741 PTH
PTH1
parathyroid hormone trichostatin A inhibits the reaction [Nickel affects the expression of PTH mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 26191 PTPN22
LYP
LYP1
LYP2
PEP
PTPN8
protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (EC:3.1.3.48) trichostatin A inhibits the reaction [Nickel affects the expression of PTPN22 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 5820 PVT1
LINC00079
NCRNA00079
Pvt1 oncogene (non-protein coding) trichostatin A inhibits the reaction [Nickel affects the expression of PVT1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 29108 PYCARD
ASC
CARD5
TMS
TMS-1
TMS1
PYD and CARD domain containing trichostatin A affects the methylation of PYCARD promoter affects methylation
promoter 17471463
C012589 29108 PYCARD
ASC
CARD5
TMS
TMS-1
TMS1
PYD and CARD domain containing [trichostatin A affects the methylation of PYCARD promoter] which affects the expression of PYCARD mRNA affects expression
/ affects methylation
mRNA / promoter 17471463
C012589 29108 PYCARD
ASC
CARD5
TMS
TMS-1
TMS1
PYD and CARD domain containing trichostatin A promotes the reaction [[decitabine affects the methylation of PYCARD promoter] which affects the expression of PYCARD mRNA] affects expression
/ affects methylation
/ increases reaction
mRNA / promoter 17471463
C012589 5879 RAC1
Rac-1
TC-25
p21-Rac1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) trichostatin A results in decreased expression of RAC1 mRNA decreases expression
mRNA 19606018
C012589 5901 RAN
ARA24
Gsp1
TC4
RAN, member RAS oncogene family trichostatin A results in decreased expression of RAN mRNA decreases expression
mRNA 19606018
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta [decitabine co-treated with trichostatin A] affects the reaction [HIST3H3 protein modified form binds to RARB gene] affects binding
/ affects cotreatment
/ affects reaction
gene 15959780
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta [decitabine co-treated with trichostatin A co-treated with Tretinoin] affects the reaction [HIST3H3 protein modified form binds to RARB promoter] affects binding
/ affects cotreatment
/ affects reaction
promoter 15959780
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta [decitabine co-treated with trichostatin A] results in increased expression of RARB mRNA affects cotreatment
/ increases expression
mRNA 15959780
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta Fenretinide promotes the reaction [trichostatin A results in increased expression of RARB mRNA] increases expression
/ increases reaction
mRNA 21319187
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta RARB protein promotes the reaction [Fenretinide promotes the reaction [trichostatin A results in increased expression of NR4A1 protein]] increases expression
/ increases reaction
protein 21319187
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta RARB protein promotes the reaction [trichostatin A results in increased expression of NR4A1 protein] increases expression
/ increases reaction
protein 21319187
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta [Tretinoin co-treated with trichostatin A] results in increased expression of RARB mRNA affects cotreatment
/ increases expression
mRNA 15959780
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta [Tretinoin co-treated with trichostatin A] results in increased expression of RARB protein affects cotreatment
/ increases expression
protein 15959780
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta [trichostatin A co-treated with Tretinoin] results in increased expression of RARB protein affects cotreatment
/ increases expression
protein 12839938
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta trichostatin A promotes the reaction [Fenretinide results in increased expression of RARB mRNA] increases expression
/ increases reaction
mRNA 21319187
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta trichostatin A promotes the reaction [HIST3H3 protein modified form binds to RARB gene] affects binding
/ increases reaction
gene 15959780
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta trichostatin A promotes the reaction [Tretinoin results in increased expression of RARB protein] increases expression
/ increases reaction
protein 15959780
C012589 5915 RARB
HAP
NR1B2
RRB2
retinoic acid receptor, beta trichostatin A results in increased expression of RARB mRNA increases expression
mRNA 15959780
21319187
C012589 5916 RARG
NR1B3
RARC
retinoic acid receptor, gamma trichostatin A promotes the reaction [Tretinoin inhibits the reaction [RARG protein binds to FOLR2 promoter]] affects binding
/ decreases reaction
/ increases reaction
protein 16740727
C012589 5918 RARRES1
LXNL
TIG1
retinoic acid receptor responder (tazarotene induced) 1 [[decitabine co-treated with trichostatin A] affects the methylation of RARRES1 promoter] which affects the expression of RARRES1 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18803327
C012589 11186 RASSF1
123F2
NORE2A
RASSF1A
RDA32
REH3P21
Ras association (RalGDS/AF-6) domain family member 1 [decitabine co-treated with trichostatin A] affects the expression of RASSF1 protein affects cotreatment
/ affects expression
protein 17019711
C012589 11186 RASSF1
123F2
NORE2A
RASSF1A
RDA32
REH3P21
Ras association (RalGDS/AF-6) domain family member 1 [[decitabine co-treated with trichostatin A] affects the methylation of RASSF1 promoter] which affects the expression of RASSF1 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18819746
C012589 5925 RB1
OSRC
RB
p105-Rb
pRb
pp110
retinoblastoma 1 [trichostatin A affects the expression of DNMT3B protein] which affects the expression of RB1 mRNA affects expression
mRNA 18544619
C012589 5925 RB1
OSRC
RB
p105-Rb
pRb
pp110
retinoblastoma 1 trichostatin A results in decreased activity of RB1 protein decreases activity
protein 15494029
C012589 5925 RB1
OSRC
RB
p105-Rb
pRb
pp110
retinoblastoma 1 trichostatin A results in decreased phosphorylation of and results in increased expression of RB1 protein decreases phosphorylation
/ increases expression
protein 15179185
C012589 116362 RBP7
CRBP4
CRBPIV
retinol binding protein 7, cellular trichostatin A results in increased expression of RBP7 mRNA increases expression
mRNA 17940511
C012589 55920 RCC2
TD-60
regulator of chromosome condensation 2 trichostatin A results in decreased expression of RCC2 mRNA decreases expression
mRNA 19606018
C012589 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A [bortezomib co-treated with trichostatin A] results in decreased expression of and results in decreased activity of RELA protein affects cotreatment
/ decreases activity
/ decreases expression
protein 16904634
C012589 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A [bortezomib co-treated with trichostatin A] results in decreased expression of RELA protein affects cotreatment
/ decreases expression
protein 16904634
C012589 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A [Plant Extracts co-treated with trichostatin A] affects the localization of RELA protein affects cotreatment
/ affects localization
protein 18709356
C012589 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A trichostatin A results in increased acetylation of and results in increased activity of RELA protein increases acetylation
/ increases activity
protein 15964798
C012589 85004 RERG
RAS-like, estrogen-regulated, growth inhibitor TFAP2C protein promotes the reaction [[decitabine co-treated with trichostatin A] results in increased expression of RERG mRNA] affects cotreatment
/ increases expression
/ increases reaction
mRNA 19458056
C012589 85004 RERG
RAS-like, estrogen-regulated, growth inhibitor [trichostatin A co-treated with TFAP2C protein] results in increased expression of RERG mRNA affects cotreatment
/ increases expression
mRNA 19458056
C012589 5978 REST
NRSF
XBR
RE1-silencing transcription factor trichostatin A results in decreased activity of REST protein decreases activity
protein 16330548
C012589 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B Azacitidine promotes the reaction [trichostatin A results in increased expression of RHOB mRNA] increases expression
/ increases reaction
mRNA 18047684
C012589 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B [trichostatin A co-treated with Azacitidine] results in increased expression of RHOB protein affects cotreatment
/ increases expression
protein 18047684
C012589 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B trichostatin A results in increased expression of RHOB mRNA increases expression
mRNA 18047684
C012589 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B trichostatin A results in increased expression of RHOB protein increases expression
protein 18047684
C012589 55178 RNMTL1
RNA methyltransferase like 1 (EC:2.1.1.-) trichostatin A inhibits the reaction [Nickel affects the expression of RNMTL1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 6175 RPLP0
L10E
LP0
P0
PRLP0
RPP0
ribosomal protein, large, P0 trichostatin A results in decreased expression of RPLP0 protein decreases expression
protein 19294695
C012589 126638 RPTN
repetin trichostatin A inhibits the reaction [Nickel affects the expression of RPTN mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 10692 RRH
retinal pigment epithelium-derived rhodopsin homolog trichostatin A inhibits the reaction [Nickel affects the expression of RRH mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 6274 S100A3
S100E
S100 calcium binding protein A3 [decitabine co-treated with trichostatin A] results in increased expression of S100A3 mRNA affects cotreatment
/ increases expression
mRNA 17891453
C012589 1901 S1PR1
CD363
CHEDG1
D1S3362
ECGF1
EDG-1
EDG1
S1P1
sphingosine-1-phosphate receptor 1 [decitabine co-treated with trichostatin A] affects the expression of S1PR1 mRNA affects cotreatment
/ affects expression
mRNA 17189669
C012589 9294 S1PR2
AGR16
EDG-5
EDG5
Gpcr13
H218
LPB2
S1P2
sphingosine-1-phosphate receptor 2 [decitabine co-treated with trichostatin A] affects the expression of S1PR2 mRNA affects cotreatment
/ affects expression
mRNA 17189669
C012589 1903 S1PR3
EDG-3
EDG3
LPB3
S1P3
sphingosine-1-phosphate receptor 3 [decitabine co-treated with trichostatin A] affects the expression of S1PR3 mRNA affects cotreatment
/ affects expression
mRNA 17189669
C012589 45384 trichostatin A results in increased expression of SAT mRNA increases expression
mRNA 19606018
C012589 6323 SCN1A
EIEE6
FEB3
FEB3A
FHM3
GEFSP2
HBSCI
NAC1
Nav1.1
SCN1
SMEI
sodium channel, voltage-gated, type I, alpha subunit trichostatin A inhibits the reaction [Nickel affects the expression of SCN1A mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 10427 SEC24B
SEC24
SEC24 family member B trichostatin A inhibits the reaction [Nickel affects the expression of SEC24B mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 6403 SELP
CD62
CD62P
GMP140
GRMP
LECAM3
PADGEM
PSEL
selectin P (granule membrane protein 140kDa, antigen CD62) trichostatin A inhibits the reaction [Nickel affects the expression of SELP mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 5413 SEPT5
CDCREL
CDCREL-1
CDCREL1
H5
HCDCREL-1
PNUTL1
septin 5 (EC:3.1.5.1) trichostatin A inhibits the reaction [Nickel affects the expression of SEPT5 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 5268 SERPINB5
PI5
maspin
serpin peptidase inhibitor, clade B (ovalbumin), member 5 [decitabine co-treated with trichostatin A] results in decreased methylation of SERPINB5 promoter affects cotreatment
/ decreases methylation
promoter 18291368
C012589 6418 SET
2PP2A
I2PP2A
IGAAD
IPP2A2
PHAPII
TAF-I
TAF-IBETA
SET nuclear oncogene [trichostatin A co-treated with decitabine] results in increased expression of SET protein affects cotreatment
/ increases expression
protein 19294695
C012589 6418 SET
2PP2A
I2PP2A
IGAAD
IPP2A2
PHAPII
TAF-I
TAF-IBETA
SET nuclear oncogene trichostatin A results in increased expression of SET protein increases expression
protein 19294695
C012589 6421 SFPQ
POMP100
PSF
splicing factor proline/glutamine-rich trichostatin A inhibits the reaction [Nickel affects the expression of SFPQ mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 6422 SFRP1
FRP
FRP-1
FRP1
FrzA
SARP2
secreted frizzled-related protein 1 [decitabine co-treated with trichostatin A] results in increased expression of SFRP1 mRNA affects cotreatment
/ increases expression
mRNA 17923031
C012589 6423 SFRP2
FRP-2
SARP1
SDF-5
secreted frizzled-related protein 2 [decitabine co-treated with trichostatin A] results in increased expression of SFRP2 mRNA affects cotreatment
/ increases expression
mRNA 17923031
C012589 6423 SFRP2
FRP-2
SARP1
SDF-5
secreted frizzled-related protein 2 [trichostatin A affects the methylation of SFRP2 protein] which affects the expression of SFRP2 mRNA affects expression
/ affects methylation
mRNA / protein 18404682
C012589 6423 SFRP2
FRP-2
SARP1
SDF-5
secreted frizzled-related protein 2 [trichostatin A affects the methylation of SFRP2 protein] which affects the expression of SFRP2 protein affects expression
/ affects methylation
protein 18404682
C012589 6424 SFRP4
FRP-4
FRPHE
sFRP-4
secreted frizzled-related protein 4 [decitabine co-treated with trichostatin A] results in increased expression of SFRP4 mRNA affects cotreatment
/ increases expression
mRNA 17923031
C012589 6425 SFRP5
SARP3
secreted frizzled-related protein 5 [decitabine co-treated with trichostatin A] results in increased expression of SFRP5 mRNA affects cotreatment
/ increases expression
mRNA 17923031
C012589 6566 SLC16A1
HHF7
MCT
MCT1
solute carrier family 16 (monocarboxylate transporter), member 1 [decitabine co-treated with trichostatin A] results in increased expression of SLC16A1 mRNA affects cotreatment
/ increases expression
mRNA 20678512
C012589 6566 SLC16A1
HHF7
MCT
MCT1
solute carrier family 16 (monocarboxylate transporter), member 1 trichostatin A results in increased expression of SLC16A1 mRNA increases expression
mRNA 20678512
C012589 6506 SLC1A2
EAAT2
GLT-1
solute carrier family 1 (glial high affinity glutamate transporter), member 2 trichostatin A results in increased expression of SLC1A2 mRNA increases expression
mRNA 19924110
C012589 6576 SLC25A1
CTP
D2L2AD
SEA
SLC20A3
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 [[decitabine co-treated with trichostatin A] promotes the reaction [SP1 protein binds to SLC25A1 promoter]] which results in increased expression of SLC25A1 mRNA affects binding
/ affects cotreatment
/ increases expression
/ increases reaction
mRNA / promoter 18706393
C012589 6576 SLC25A1
CTP
D2L2AD
SEA
SLC20A3
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 [decitabine co-treated with trichostatin A] results in increased expression of SLC25A1 mRNA affects cotreatment
/ increases expression
mRNA 18706393
C012589 6576 SLC25A1
CTP
D2L2AD
SEA
SLC20A3
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 [decitabine co-treated with trichostatin A] results in increased expression of SLC25A1 protein affects cotreatment
/ increases expression
protein 18706393
C012589 6576 SLC25A1
CTP
D2L2AD
SEA
SLC20A3
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 trichostatin A promotes the reaction [SP1 protein binds to SLC25A1 promoter] affects binding
/ increases reaction
promoter 18706393
C012589 6576 SLC25A1
CTP
D2L2AD
SEA
SLC20A3
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 trichostatin A results in increased expression of SLC25A1 mRNA increases expression
mRNA 18706393
C012589 6576 SLC25A1
CTP
D2L2AD
SEA
SLC20A3
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 trichostatin A results in increased expression of SLC25A1 protein increases expression
protein 18706393
C012589 6518 SLC2A5
GLUT-5
GLUT5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5 trichostatin A inhibits the reaction [Nickel affects the expression of SLC2A5 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 113829 SLC35A4
solute carrier family 35, member A4 trichostatin A inhibits the reaction [Nickel affects the expression of SLC35A4 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 54407 SLC38A2
ATA2
PRO1068
SAT2
SNAT2
solute carrier family 38, member 2 trichostatin A inhibits the reaction [Nickel affects the expression of SLC38A2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]] decreases expression
/ decreases reaction
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]] decreases expression
/ decreases reaction
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]] decreases reaction
/ increases cleavage
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]] decreases reaction
/ increases expression
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form results in decreased susceptibility to trichostatin A] decreases reaction
/ decreases response to substance
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein] decreases expression
/ decreases reaction
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein] decreases expression
/ decreases reaction
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein] decreases reaction
/ increases cleavage
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein] decreases reaction
/ increases expression
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 SLC39A6 mutant form results in decreased susceptibility to trichostatin A decreases response to substance
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 trichostatin A results in increased expression of SLC39A6 mRNA increases expression
mRNA 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 trichostatin A results in increased expression of SLC39A6 protein increases expression
protein 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]]] decreases expression
/ decreases reaction
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]]] decreases expression
/ decreases reaction
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]]] decreases reaction
/ increases cleavage
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]]] decreases reaction
/ increases expression
mutant form 19887557
C012589 25800 SLC39A6
LIV-1
solute carrier family 39 (zinc transporter), member 6 Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form results in decreased susceptibility to trichostatin A]] decreases reaction
/ decreases response to substance
mutant form 19887557
C012589 6528 SLC5A5
NIS
TDH1
solute carrier family 5 (sodium/iodide cotransporter), member 5 trichostatin A results in increased expression of SLC5A5 mRNA increases expression
mRNA 16954431
C012589 6528 SLC5A5
NIS
TDH1
solute carrier family 5 (sodium/iodide cotransporter), member 5 trichostatin A results in increased expression of SLC5A5 protein increases expression
protein 16954431
C012589 6622 SNCA
NACP
PARK1
PARK4
PD1
synuclein, alpha (non A4 component of amyloid precursor) [decitabine co-treated with trichostatin A] results in increased expression of SNCA mRNA affects cotreatment
/ increases expression
mRNA 17891453
C012589 6623 SNCG
BCSG1
SR
synuclein, gamma (breast cancer-specific protein 1) trichostatin A inhibits the reaction [Nickel affects the expression of SNCG mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 6648 SOD2
IPOB
MNSOD
MVCD6
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) [trichostatin A co-treated with decitabine] results in increased expression of SOD2 protein affects cotreatment
/ increases expression
protein 19294695
C012589 6667 SP1
Sp1 transcription factor [decitabine co-treated with trichostatin A] promotes the reaction [SP1 protein binds to CLDN3 promoter] affects binding
/ affects cotreatment
/ increases reaction
protein 17986852
C012589 6667 SP1
Sp1 transcription factor [[decitabine co-treated with trichostatin A] promotes the reaction [SP1 protein binds to SLC25A1 promoter]] which results in increased expression of SLC25A1 mRNA affects binding
/ affects cotreatment
/ increases expression
/ increases reaction
protein 18706393
C012589 6667 SP1
Sp1 transcription factor SP1 protein affects the reaction [trichostatin A affects the expression of GDF15 mRNA] affects expression
/ affects reaction
protein 18801729
C012589 6667 SP1
Sp1 transcription factor trichostatin A affects the expression of SP1 mRNA affects expression
mRNA 18801729
C012589 6667 SP1
Sp1 transcription factor trichostatin A affects the expression of SP1 protein affects expression
protein 18801729
C012589 6667 SP1
Sp1 transcription factor trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of SP1 mRNA] decreases reaction
/ increases expression
mRNA 21911040
C012589 6667 SP1
Sp1 transcription factor trichostatin A promotes the reaction [SP1 protein binds to PDK4 promoter] affects binding
/ increases reaction
protein 16757381
C012589 6667 SP1
Sp1 transcription factor trichostatin A promotes the reaction [SP1 protein binds to SLC25A1 promoter] affects binding
/ increases reaction
protein 18706393
C012589 6667 SP1
Sp1 transcription factor trichostatin A promotes the reaction [Tretinoin promotes the reaction [SP1 protein binds to FOLR2 promoter]] affects binding
/ increases reaction
protein 16740727
C012589 6667 SP1
Sp1 transcription factor trichostatin A results in increased activity of SP1 protein increases activity
protein 16757381
C012589 6670 SP3
SPR2
Sp3 transcription factor [decitabine co-treated with trichostatin A] promotes the reaction [SP3 protein binds to CLDN3 promoter] affects binding
/ affects cotreatment
/ increases reaction
protein 17986852
C012589 10653 SPINT2
DIAR3
HAI-2
HAI2
Kop
PB
serine peptidase inhibitor, Kunitz type, 2 trichostatin A inhibits the reaction [Nickel affects the expression of SPINT2 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 6755 SSTR5
SS-5-R
somatostatin receptor 5 [decitabine co-treated with trichostatin A] affects the expression of SSTR5 mRNA affects cotreatment
/ affects expression
mRNA 18575731
C012589 20941 trichostatin A inhibits the reaction [Nickel affects the expression of SVS4 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 20945 trichostatin A inhibits the reaction [Nickel affects the expression of SVS6 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 6867 TACC1
Ga55
transforming, acidic coiled-coil containing protein 1 trichostatin A results in increased expression of TACC1 mRNA increases expression
mRNA 19606018
C012589 6925 TCF4
E2-2
ITF-2
ITF2
PTHS
SEF-2
SEF2
SEF2-1
SEF2-1A
SEF2-1B
TCF-4
bHLHb19
transcription factor 4 trichostatin A inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]] affects binding
/ decreases reaction
/ increases reaction
protein 22552774
C012589 6925 TCF4
E2-2
ITF-2
ITF2
PTHS
SEF-2
SEF2
SEF2-1
SEF2-1A
SEF2-1B
TCF-4
bHLHb19
transcription factor 4 trichostatin A inhibits the reaction [Dibutyl Phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]] affects binding
/ decreases reaction
/ increases reaction
protein 22552774
C012589 21580 trichostatin A inhibits the reaction [Nickel affects the expression of TCRB-J mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 7015 TERT
CMM9
DKCA2
DKCB4
EST2
PFBMFT1
TCS1
TP2
TRT
hEST2
hTRT
telomerase reverse transcriptase (EC:2.7.7.49) trichostatin A affects the expression of TERT mRNA affects expression
mRNA 16051188
C012589 7015 TERT
CMM9
DKCA2
DKCB4
EST2
PFBMFT1
TCS1
TP2
TRT
hEST2
hTRT
telomerase reverse transcriptase (EC:2.7.7.49) trichostatin A affects the expression of TERT protein affects expression
protein 16051188
C012589 7021 TFAP2B
AP-2B
AP2-B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta) trichostatin A inhibits the reaction [Nickel affects the expression of TFAP2B mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 7022 TFAP2C
AP2-GAMMA
ERF1
TFAP2G
hAP-2g
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) [decitabine co-treated with trichostatin A] promotes the reaction [TFAP2C protein binds to ESR1 promoter] affects binding
/ affects cotreatment
/ increases reaction
protein 19458056
C012589 7022 TFAP2C
AP2-GAMMA
ERF1
TFAP2G
hAP-2g
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) [decitabine co-treated with trichostatin A] promotes the reaction [TFAP2C protein results in increased expression of ESR1 mRNA] affects cotreatment
/ increases expression
/ increases reaction
protein 19458056
C012589 7022 TFAP2C
AP2-GAMMA
ERF1
TFAP2G
hAP-2g
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) TFAP2C protein promotes the reaction [[decitabine co-treated with trichostatin A] results in increased expression of ESR1 mRNA] affects cotreatment
/ increases expression
/ increases reaction
protein 19458056
C012589 7022 TFAP2C
AP2-GAMMA
ERF1
TFAP2G
hAP-2g
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) TFAP2C protein promotes the reaction [[decitabine co-treated with trichostatin A] results in increased expression of RERG mRNA] affects cotreatment
/ increases expression
/ increases reaction
protein 19458056
C012589 7022 TFAP2C
AP2-GAMMA
ERF1
TFAP2G
hAP-2g
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) [trichostatin A co-treated with TFAP2C protein] results in increased expression of ESR1 mRNA affects cotreatment
/ increases expression
protein 19458056
C012589 7022 TFAP2C
AP2-GAMMA
ERF1
TFAP2G
hAP-2g
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) [trichostatin A co-treated with TFAP2C protein] results in increased expression of RERG mRNA affects cotreatment
/ increases expression
protein 19458056
C012589 7031 TFF1
BCEI
D21S21
HP1.A
HPS2
pNR-2
pS2
trefoil factor 1 [decitabine co-treated with trichostatin A] affects the expression of TFF1 mRNA affects cotreatment
/ affects expression
mRNA 18264725
C012589 7031 TFF1
BCEI
D21S21
HP1.A
HPS2
pNR-2
pS2
trefoil factor 1 [decitabine co-treated with trichostatin A] results in increased expression of TFF1 mRNA affects cotreatment
/ increases expression
mRNA 17533736
C012589 7980 TFPI2
PP5
REF1
TFPI-2
tissue factor pathway inhibitor 2 [decitabine co-treated with trichostatin A] affects the methylation of TFPI2 promoter affects cotreatment
/ affects methylation
promoter 17464989
C012589 7980 TFPI2
PP5
REF1
TFPI-2
tissue factor pathway inhibitor 2 [[decitabine co-treated with trichostatin A] affects the methylation of TFPI2 promoter] which affects the expression of TFPI2 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 17464989
C012589 7040 TGFB1
CED
DPD1
LAP
TGFB
TGFbeta
transforming growth factor, beta 1 trichostatin A promotes the reaction [IL1B protein results in increased expression of TGFB1 mRNA] increases expression
/ increases reaction
mRNA 16365456
C012589 7040 TGFB1
CED
DPD1
LAP
TGFB
TGFbeta
transforming growth factor, beta 1 trichostatin A results in increased expression of TGFB1 mRNA increases expression
mRNA 16365456
C012589 7048 TGFBR2
AAT3
FAA3
LDS1B
LDS2B
MFS2
RIIC
TAAD2
TGFR-2
TGFbeta-RII
transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30) trichostatin A promotes the reaction [EP300 protein binds to TGFBR2 promoter] affects binding
/ increases reaction
promoter 15647279
C012589 7048 TGFBR2
AAT3
FAA3
LDS1B
LDS2B
MFS2
RIIC
TAAD2
TGFR-2
TGFbeta-RII
transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30) trichostatin A promotes the reaction [PCAF protein binds to TGFBR2 promoter] affects binding
/ increases reaction
promoter 15647279
C012589 7048 TGFBR2
AAT3
FAA3
LDS1B
LDS2B
MFS2
RIIC
TAAD2
TGFR-2
TGFbeta-RII
transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30) trichostatin A results in increased expression of TGFBR2 mRNA increases expression
mRNA 15647279
C012589 7048 TGFBR2
AAT3
FAA3
LDS1B
LDS2B
MFS2
RIIC
TAAD2
TGFR-2
TGFbeta-RII
transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30) trichostatin A results in increased expression of TGFBR2 protein increases expression
protein 15647279
C012589 51298 THEG
CT56
THEG1
theg spermatid protein trichostatin A inhibits the reaction [Nickel affects the expression of THEG mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 7082 TJP1
ZO-1
tight junction protein 1 trichostatin A results in increased expression of TJP1 mRNA increases expression
mRNA 18661270
C012589 8795 TNFRSF10B
CD262
DR5
KILLER
KILLER/DR5
TRAIL-R2
TRAILR2
TRICK2
TRICK2A
TRICK2B
TRICKB
ZTNFR9
tumor necrosis factor receptor superfamily, member 10b [Plant Extracts co-treated with trichostatin A] results in increased expression of TNFRSF10B protein affects cotreatment
/ increases expression
protein 18709356
C012589 8795 TNFRSF10B
CD262
DR5
KILLER
KILLER/DR5
TRAIL-R2
TRAILR2
TRICK2
TRICK2A
TRICK2B
TRICKB
ZTNFR9
tumor necrosis factor receptor superfamily, member 10b trichostatin A results in increased expression of TNFRSF10B mRNA increases expression
mRNA 15964798
C012589 8795 TNFRSF10B
CD262
DR5
KILLER
KILLER/DR5
TRAIL-R2
TRAILR2
TRICK2
TRICK2A
TRICK2B
TRICKB
ZTNFR9
tumor necrosis factor receptor superfamily, member 10b trichostatin A results in increased expression of TNFRSF10B protein increases expression
protein 15964798
C012589 7132 TNFRSF1A
CD120a
FPF
MS5
TBP1
TNF-R
TNF-R-I
TNF-R55
TNFAR
TNFR1
TNFR1-d2
TNFR55
TNFR60
p55
p55-R
p60
tumor necrosis factor receptor superfamily, member 1A [Genistein co-treated with trichostatin A] results in increased expression of TNFRSF1A mRNA affects cotreatment
/ increases expression
mRNA 22626855
C012589 7132 TNFRSF1A
CD120a
FPF
MS5
TBP1
TNF-R
TNF-R-I
TNF-R55
TNFAR
TNFR1
TNFR1-d2
TNFR55
TNFR60
p55
p55-R
p60
tumor necrosis factor receptor superfamily, member 1A [Genistein co-treated with trichostatin A] results in increased expression of TNFRSF1A protein affects cotreatment
/ increases expression
protein 22626855
C012589 8744 TNFSF9
4-1BB-L
CD137L
tumor necrosis factor (ligand) superfamily, member 9 [Ionomycin co-treated with Phorbol Esters] promotes the reaction [trichostatin A results in increased expression of TNFSF9 mRNA] affects cotreatment
/ increases expression
/ increases reaction
mRNA 19759901
C012589 8744 TNFSF9
4-1BB-L
CD137L
tumor necrosis factor (ligand) superfamily, member 9 mithramycin A inhibits the reaction [trichostatin A results in increased expression of TNFSF9 mRNA] decreases reaction
/ increases expression
mRNA 19759901
C012589 8744 TNFSF9
4-1BB-L
CD137L
tumor necrosis factor (ligand) superfamily, member 9 trichostatin A results in increased expression of TNFSF9 mRNA increases expression
mRNA 19759901
C012589 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 [Genistein co-treated with trichostatin A] results in increased expression of TP53 protein affects cotreatment
/ increases expression
protein 22626855
C012589 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 leptomycin B inhibits the reaction [TP53 protein results in increased susceptibility to trichostatin A] decreases reaction
/ increases response to substance
protein 16467109
C012589 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 pifithrin inhibits the reaction [TP53 protein results in increased susceptibility to trichostatin A] decreases reaction
/ increases response to substance
protein 16467109
C012589 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 TP53 protein affects the reaction [trichostatin A results in increased expression of TP63 protein alternative form] affects reaction
/ increases expression
protein 20043870
C012589 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 TP53 protein results in increased susceptibility to trichostatin A increases response to substance
protein 16467109
C012589 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 trichostatin A results in decreased expression of TP53 mRNA decreases expression
mRNA 19606018
C012589 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 trichostatin A results in decreased expression of TP53 protein decreases expression
protein 15179185
C012589 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 trichostatin A results in decreased expression of TP53 protein mutant form decreases expression
protein 15179185
C012589 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 trichostatin A results in increased acetylation of and results in increased activity of TP53 protein increases acetylation
/ increases activity
protein 15964798
C012589 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 trichostatin A results in increased expression of TP53 mRNA increases expression
mRNA 16865256
C012589 94241 TP53INP1
SIP
TP53DINP1
TP53INP1A
TP53INP1B
Teap
p53DINP1
tumor protein p53 inducible nuclear protein 1 [[decitabine co-treated with trichostatin A] affects the methylation of TP53INP1 promoter] which affects the expression of TP53INP1 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18803327
C012589 8626 TP63
AIS
B(p51A)
B(p51B)
EEC3
KET
LMS
NBP
OFC8
RHS
SHFM4
TP53CP
TP53L
TP73L
p40
p51
p53CP
p63
p73H
p73L
tumor protein p63 Cycloheximide inhibits the reaction [trichostatin A results in increased expression of TP63 protein alternative form] decreases reaction
/ increases expression
protein 20043870
C012589 8626 TP63
AIS
B(p51A)
B(p51B)
EEC3
KET
LMS
NBP
OFC8
RHS
SHFM4
TP53CP
TP53L
TP73L
p40
p51
p53CP
p63
p73H
p73L
tumor protein p63 TP53 protein affects the reaction [trichostatin A results in increased expression of TP63 protein alternative form] affects reaction
/ increases expression
protein 20043870
C012589 8626 TP63
AIS
B(p51A)
B(p51B)
EEC3
KET
LMS
NBP
OFC8
RHS
SHFM4
TP53CP
TP53L
TP73L
p40
p51
p53CP
p63
p73H
p73L
tumor protein p63 TP63 protein modified form results in increased susceptibility to trichostatin A increases response to substance
protein 21527555
C012589 8626 TP63
AIS
B(p51A)
B(p51B)
EEC3
KET
LMS
NBP
OFC8
RHS
SHFM4
TP53CP
TP53L
TP73L
p40
p51
p53CP
p63
p73H
p73L
tumor protein p63 trichostatin A results in increased expression of and results in increased cleavage of and results in increased activity of TP63 protein alternative form increases activity
/ increases cleavage
/ increases expression
protein 20043870
C012589 8626 TP63
AIS
B(p51A)
B(p51B)
EEC3
KET
LMS
NBP
OFC8
RHS
SHFM4
TP53CP
TP53L
TP73L
p40
p51
p53CP
p63
p73H
p73L
tumor protein p63 [trichostatin A results in increased expression of and results in increased cleavage of and results in increased activity of TP63 protein alternative form] which affects the susceptibility to Antineoplastic Agents affects response to substance
/ increases activity
/ increases cleavage
/ increases expression
protein 20043870
C012589 8626 TP63
AIS
B(p51A)
B(p51B)
EEC3
KET
LMS
NBP
OFC8
RHS
SHFM4
TP53CP
TP53L
TP73L
p40
p51
p53CP
p63
p73H
p73L
tumor protein p63 trichostatin A results in increased expression of TP63 mRNA alternative form increases expression
mRNA 20043870
C012589 7170 TPM3
CAPM1
CFTD
NEM1
OK/SW-cl.5
TM-5
TM3
TM30
TM30nm
TM5
TPMsk3
TRK
hscp30
tropomyosin 3 trichostatin A results in decreased expression of TPM3 protein decreases expression
protein 19294695
C012589 7171 TPM4
tropomyosin 4 trichostatin A results in decreased expression of TPM4 protein decreases expression
protein 19294695
C012589 7178 TPT1
HRF
TCTP
p02
p23
tumor protein, translationally-controlled 1 [trichostatin A co-treated with decitabine] results in decreased expression of TPT1 protein affects cotreatment
/ decreases expression
protein 19294695
C012589 7178 TPT1
HRF
TCTP
p02
p23
tumor protein, translationally-controlled 1 trichostatin A results in decreased expression of TPT1 protein decreases expression
protein 19294695
C012589 22974 TPX2
C20orf1
C20orf2
DIL-2
DIL2
FLS353
GD:C20orf1
HCA519
HCTP4
REPP86
p100
TPX2, microtubule-associated trichostatin A results in decreased expression of TPX2 mRNA decreases expression
mRNA 19606018
C012589 8717 TRADD
Hs.89862
TNFRSF1A-associated via death domain [Plant Extracts co-treated with trichostatin A] results in increased expression of TRADD protein affects cotreatment
/ increases expression
protein 18709356
C012589 7225 TRPC6
FSGS2
TRP6
transient receptor potential cation channel, subfamily C, member 6 trichostatin A inhibits the reaction [Nickel affects the expression of TRPC6 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 7248 TSC1
LAM
TSC
tuberous sclerosis 1 trichostatin A inhibits the reaction [Nickel affects the expression of TSC1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 7253 TSHR
CHNG1
LGR3
hTSHR-I
thyroid stimulating hormone receptor trichostatin A results in increased expression of TSHR mRNA increases expression
mRNA 17679169
C012589 108314 trichostatin A affects the expression of TSP1 mRNA affects expression
mRNA 16505122
C012589 7298 TYMS
HST422
TMS
TS
thymidylate synthetase (EC:2.1.1.45) benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trichostatin A results in decreased expression of TYMS protein] decreases expression
/ decreases reaction
protein 17172411
C012589 7298 TYMS
HST422
TMS
TS
thymidylate synthetase (EC:2.1.1.45) Cycloheximide inhibits the reaction [trichostatin A results in decreased expression of TYMS mRNA] decreases expression
/ decreases reaction
mRNA 17172411
C012589 7298 TYMS
HST422
TMS
TS
thymidylate synthetase (EC:2.1.1.45) trichostatin A results in decreased expression of TYMS mRNA decreases expression
mRNA 17172411
19606018
C012589 7298 TYMS
HST422
TMS
TS
thymidylate synthetase (EC:2.1.1.45) trichostatin A results in decreased expression of TYMS protein decreases expression
protein 17172411
C012589 7298 TYMS
HST422
TMS
TS
thymidylate synthetase (EC:2.1.1.45) [trichostatin A results in decreased expression of TYMS protein] which results in increased susceptibility to Fluorouracil decreases expression
/ increases response to substance
protein 17172411
C012589 7298 TYMS
HST422
TMS
TS
thymidylate synthetase (EC:2.1.1.45) trichostatin A results in increased degradation of TYMS protein increases degradation
protein 17172411
C012589 7301 TYRO3
BYK
Dtk
RSE
Sky
Tif
TYRO3 protein tyrosine kinase (EC:2.7.10.1) trichostatin A inhibits the reaction [Nickel affects the expression of TYRO3 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 7345 UCHL1
NDGOA
PARK5
PGP_9.5
PGP9.5
PGP95
Uch-L1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (EC:3.4.19.12) [[decitabine co-treated with trichostatin A] affects the methylation of UCHL1 promoter] which affects the expression of UCHL1 mRNA affects cotreatment
/ affects expression
/ affects methylation
mRNA / promoter 18666234
C012589 81622 UNC93B1
IIAE1
UNC93
UNC93B
Unc-93B1
unc-93 homolog B1 (C. elegans) trichostatin A inhibits the reaction [Nickel affects the expression of UNC93B1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 6845 VAMP7
SYBL1
TI-VAMP
TIVAMP
VAMP-7
vesicle-associated membrane protein 7 trichostatin A inhibits the reaction [Nickel affects the expression of VAMP7 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 7412 VCAM1
CD106
INCAM-100
vascular cell adhesion molecule 1 trichostatin A inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein] decreases reaction
/ increases expression
protein 19281832
C012589 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor [decitabine co-treated with trichostatin A] results in increased expression of VDR mRNA affects cotreatment
/ increases expression
mRNA 17891453
C012589 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor [decitabine co-treated with trichostatin A] results in increased expression of VDR protein affects cotreatment
/ increases expression
protein 17891453
C012589 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor trichostatin A inhibits the reaction [Nickel affects the expression of VDR mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 7431 VIM
CTRCT30
vimentin trichostatin A inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]] affects binding
/ decreases reaction
/ increases reaction
protein 22552774
C012589 7431 VIM
CTRCT30
vimentin trichostatin A inhibits the reaction [Dibutyl Phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]] affects binding
/ decreases reaction
/ increases reaction
protein 22552774
C012589 22305 trichostatin A inhibits the reaction [Nickel affects the expression of VMN2R37 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 55737 VPS35
MEM3
PARK17
vacuolar protein sorting 35 homolog (S. cerevisiae) trichostatin A inhibits the reaction [Nickel affects the expression of VPS35 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 23559 WBP1
WBP-1
WW domain binding protein 1 trichostatin A inhibits the reaction [Nickel affects the expression of WBP1 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 11197 WIF1
WIF-1
WNT inhibitory factor 1 [decitabine co-treated with trichostatin A] results in increased expression of WIF1 mRNA affects cotreatment
/ increases expression
mRNA 17923031
C012589 51741 WWOX
D16S432E
FOR
FRA16D
HHCMA56
PRO0128
SDR41C1
WOX1
WW domain containing oxidoreductase (EC:1.1.1.-) [decitabine co-treated with trichostatin A] affects the expression of WWOX protein affects cotreatment
/ affects expression
protein 17019711
C012589 7503 XIST
DXS1089
DXS399E
LINC00001
NCRNA00001
SXI1
swd66
X inactive specific transcript (non-protein coding) trichostatin A inhibits the reaction [Nickel affects the expression of XIST mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 7547 ZIC3
HTX
HTX1
VACTERLX
ZNF203
Zic family member 3 trichostatin A inhibits the reaction [Nickel affects the expression of ZIC3 mRNA] affects expression
/ decreases reaction
mRNA 14575637
C012589 51364 ZMYND10
BLU
FLU
zinc finger, MYND-type containing 10 [decitabine co-treated with trichostatin A] affects the expression of ZMYND10 mRNA affects cotreatment
/ affects expression
mRNA 18819746
C012589 9753 ZSCAN12
ZFP96
ZNF29K1
ZNF305
ZNF96
dJ29K1.2
zinc finger and SCAN domain containing 12 [decitabine co-treated with trichostatin A] inhibits the reaction [sodium arsenite affects the methylation of ZSCAN12 promoter] affects cotreatment
/ affects methylation
/ decreases reaction
promoter 18448484

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (23)

OMIM preferred title UniProt
#600430 Brachydactyly-mental retardation syndrome; bdmr P56524
#300882 Cornelia de lange syndrome 5; cdls5 Q9BY41
#219700 Cystic fibrosis; cf P13569
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277180 Vas deferens, congenital bilateral aplasia of; cbavd P13569
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#309585 Wilson-turner x-linked mental retardation syndrome; wts Q9BY41

KEGG DISEASE (15)

KEGG disease name UniProt
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00218 Cystic fibrosis (CF) P13569 (related)
H00933 Hereditary pancreatitis P13569 (related)
H01033 Congenital bilateral absence of vas deferens P13569 (related)
H00561 Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome P56524 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)

Diseases related to CTD interactions

16 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D000014 C012589 Abnormalities, Drug-Induced marker/mechanism
15901671
17320131
19850124
D000015 C012589 Abnormalities, Multiple marker/mechanism
15901671
C538231 C012589 Adenocarcinoma of lung therapeutic
22626855
D001848 C012589 Bone Diseases, Developmental marker/mechanism
17320131
D019970 C012589 Cocaine-Related Disorders therapeutic
18799668
D004701 C012589 Endocrine Gland Neoplasms therapeutic
19294695
D005909 C012589 Glioblastoma therapeutic
18801729
D015470 C012589 Leukemia, Myeloid, Acute therapeutic
18206229
D008545 C012589 Melanoma therapeutic
16505122
D009101 C012589 Multiple Myeloma therapeutic
18172295
D010051 C012589 Ovarian Neoplasms therapeutic
19331143
D010190 C012589 Pancreatic Neoplasms therapeutic
19294695
D010490 C012589 Pericardial Effusion marker/mechanism
15901671
D049188 C012589 Prenatal Injuries marker/mechanism
15901671
D055728 C012589 Primary Myelofibrosis therapeutic
17616702
D011471 C012589 Prostatic Neoplasms therapeutic
18798265
19789329