Species

KNApSAcK Entry

Organism name Streptomyces hygroscopicus
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces hygroscopicus
Linked NCBI taxonomy ID 1912
Linked level species

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (23)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00017593 External link 512 CP 80219
C065223
No. 199
C00018095 External link 512 D-1-Deoxyxylulose
/ 1-Deoxy-D-xylulose
/ 1-Deoxy-D-threo-pentulose
C029724
No. 1614
C00000785 External link 512 DMBA
/ MP 102
/ Demethylbialaphos
No. 2698
C00000782 External link 512 BA
/ Bialaphos
CHEMBL2000864
C003122
No. 2698
C00000794 External link 512 N-AcDMBA
/ N-Acetyldemethylbialaphos
No. 2698
C00000916 External link 512 HEP
/ 2-Hydroxyethylphosphonic acid
No. 3559
C00000791 External link 512 HMP
/ Hydroxymethylphosphonic acid
No. 3559
C00035467 External link 512 1-Acetyl-N-salicyloyl-2-aminopropan-3-ol
No. 3798
C00035706 External link 512 N-Salicyloyl-2-aminopropan-1,3-diol
No. 3798
C00035707 External link 512 N-Salicyloyl-2-aminopropan-1-ol
No. 3798
C00042599 External link 512 Hygrocin A
CHEMBL517001
No. 4755
C00042600 External link 512 Hygrocin B
CHEMBL518225
No. 4755
C00000797 External link 512 PT
/ Phosphinothricin
CHEMBL145114
CHEMBL450298
5 / 2 / 1 No. 4761
C00000795 External link 512 PAL
/ Phosphinoalanine
CHEMBL241972
4 / 1 / 0 No. 4761
C00016002 External link 512 TSA
/ Trichostatin A
/ (R)-Trichostatin A
CHEMBL99
CHEMBL26159
C012589
25 / 23 / 15 397 / 16 No. 5192
C00000798 External link 512 PEP
/ Phosphoenolpyruvate
/ Phosphoenolpyruvic acid
CHEMBL1235228
2 / 2 / 1 No. 6199
C00000796 External link 512 PPA
/ Phosphinopyruvate
No. 7288
C00028345 External link 512 Himastatin
C066106
No. 7838
C00000783 External link 512 CPEP
/ Carboxyphosphoenolpyruvate
No. 8352
C00000801 External link 512 PnPy
/ Phosphonopyruvate
/ Phosphonopyruvic acid
No. 8626
C00000793 External link 512 N-AcDMPT
/ N-Acethyldemethylphosphinothricin
No. 8712
C00018072 External link 512 Trichostatin B
No. 8837
C00000800 External link 512 PF
/ Phosphonoformic acid
CHEMBL666
D017245
95 / 39 / 33 5 / 50 No. 8860

Human Protein / Gene in interactions

127 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q14416 Metabotropic glutamate receptor 2 Metabotropic glutamate receptor C00000795 C00000797 0 / 0
P41594 Metabotropic glutamate receptor 5 Metabotropic glutamate receptor C00000795 C00000797 0 / 0
Q14832 Metabotropic glutamate receptor 3 Metabotropic glutamate receptor C00000795 C00000797 0 / 0
Q13255 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor C00000795 C00000797 1 / 0
P22303 Acetylcholinesterase Hydrolase C00000800 1 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000800 0 / 3
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00000800 2 / 2
P08246 Neutrophil elastase S1A C00000800 2 / 1
P33765 Adenosine receptor A3 Adenosine receptor C00000800 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00000800 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00000800 0 / 0
P04062 Glucosylceramidase Enzyme C00016002 6 / 4
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00000800 0 / 0
P29466 Caspase-1 C14 C00000800 0 / 0
P17252 Protein kinase C alpha type Alpha C00000800 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00000800 0 / 0
Q96DB2 Histone deacetylase 11 Hydrolase C00016002 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00000800 2 / 2
Q13547 Histone deacetylase 1 Hydrolase C00016002 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00000800 1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00000800 0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00000800 1 / 1
P25021 Histamine H2 receptor Histamine receptor C00000800 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00000800 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00000800 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00000800 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00000800 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00000800 0 / 0
Q9BY41 Histone deacetylase 8 Hydrolase C00016002 2 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00000800 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00000800 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00000800 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000800 0 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00000800 1 / 8
P11473 Vitamin D3 receptor NR1I1 C00016002 2 / 3
P14416 D(2) dopamine receptor Dopamine receptor C00000800 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00000800 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00000800 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00000800 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00000800 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00000800 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00000800 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00000800 1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00000800 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00000800 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00016002 0 / 0
Q92769 Histone deacetylase 2 Hydrolase C00016002 0 / 0
Q9UQL6 Histone deacetylase 5 Hydrolase C00016002 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00000800 0 / 0
Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 Enzyme C00016002 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00000800 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00000800 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00000800 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00000800 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00000800 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00000800 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00000800 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00000800 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00000800 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00000800 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00000800 1 / 0
P00915 Carbonic anhydrase 1 Lyase C00000800 0 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00000800 0 / 0
P08311 Cathepsin G S1A C00000800 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00000800 1 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000800 1 / 0
P03956 Interstitial collagenase M10A C00000800 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00000800 0 / 0
Q15393 Splicing factor 3B subunit 3 Unclassified protein C00016002 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00016002 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00000800 0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00000800 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00000800 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00000800 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00000800 2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00000800 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00000800 1 / 0
P21452 Substance-K receptor Neurokinin receptor C00000800 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00000800 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00000800 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00000800 0 / 0
Q969S8 Histone deacetylase 10 Hydrolase C00016002 0 / 0
P13726 Tissue factor Membrane receptor C00016002 0 / 0
O15379 Histone deacetylase 3 Hydrolase C00016002 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00000800 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00000800 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00000800 2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000800 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00000800 0 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00016002 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00000800 0 / 0
P03372 Estrogen receptor NR3A1 C00000800 1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00000800 1 / 0
P09884 DNA polymerase alpha catalytic subunit Transferase C00000800 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00000800 0 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00000800 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00000800 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00000800 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00000800 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00000800 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00000800 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00000800 0 / 0
P56524 Histone deacetylase 4 Hydrolase C00016002 1 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein C00016002 2 / 0
Q8WUI4 Histone deacetylase 7 Hydrolase C00016002 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000800 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000800 0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00000800 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00016002 4 / 3
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00000800 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00000800 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00000800 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00000800 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00000800 1 / 1
P06239 Tyrosine-protein kinase Lck Src C00000800 0 / 1
Q16637 Survival motor neuron protein Unclassified protein C00016002 4 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00000800 0 / 0
P13569 Cystic fibrosis transmembrane conductance regulator chloride C00016002 2 / 3
Q9UBN7 Histone deacetylase 6 Hydrolase C00016002 0 / 0
P12955 Xaa-Pro dipeptidase M24B C00000798 1 / 1
P15104 Glutamine synthetase Enzyme C00000797 1 / 1
Q9UKV0 Histone deacetylase 9 Hydrolase C00016002 0 / 0
P28340 DNA polymerase delta catalytic subunit Transferase C00000800 2 / 0
P22748 Carbonic anhydrase 4 Lyase C00000800 1 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00016002 0 / 0
Q92959 Solute carrier organic anion transporter family member 2A1 Unclassified protein C00000798 1 / 0
Q9Y618 Nuclear receptor corepressor 2 Unclassified protein C00016002 0 / 0

401 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00000800 C00016002
6755 SSTR5, SS-5-R somatostatin receptor 5 C00016002
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00016002
8714 ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 C00016002
25 ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) C00016002
132 ADK, AK adenosine kinase (EC:2.7.1.20) C00016002
196 AHR, bHLHe76 aryl hydrocarbon receptor C00016002
9131 AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8 apoptosis-inducing factor, mitochondrion-associated, 1 C00016002
9590 AKAP12, AKAP250, SSeCKS A kinase (PRKA) anchor protein 12 C00016002
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00016002
51129 ANGPTL4, ANGPTL2, ARP4, FIAF, HARP, HFARP, NL2, PGAR, UNQ171, pp1158 angiopoietin-like 4 C00016002
302 ANXA2, ANX2, ANX2L4, CAL1H, LIP2, LPC2, LPC2D, P36, PAP-IV annexin A2 C00016002
317 APAF1, APAF-1, CED4 apoptotic peptidase activating factor 1 C00016002
328 APEX1, APE, APE1, APEN, APEX, APX, HAP1, REF1 APEX nuclease (multifunctional DNA repair enzyme) 1 (EC:4.2.99.18) C00016002
347 APOD apolipoprotein D C00016002
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00016002
10565 ARFGEF1, ARFGEP1, BIG1, P200 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) C00016002
201176 ARHGAP27, CAMGAP1, PP905, SH3D20, SH3P20 Rho GTPase activating protein 27 C00016002
27237 ARHGEF16, GEF16, NBR Rho guanine nucleotide exchange factor (GEF) 16 C00016002
11872 C00016002
430 ASCL2, ASH2, HASH2, MASH2, bHLHa45 achaete-scute family bHLH transcription factor 2 C00016002
51802 ASIC5, ACCN5, HINAC, INAC acid-sensing (proton-gated) ion channel family member 5 C00016002
482 ATP1B2, AMOG ATPase, Na+/K+ transporting, beta 2 polypeptide (EC:3.6.3.9) C00016002
489 ATP2A3, SERCA3 ATPase, Ca++ transporting, ubiquitous (EC:3.6.3.8) C00016002
506 ATP5B, ATPMB, ATPSB ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14) C00016002
6790 AURKA, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7 aurora kinase A (EC:2.7.11.1) C00016002
9212 AURKB, AIK2, AIM-1, AIM1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5, aurkb-sv1, aurkb-sv2 aurora kinase B (EC:2.7.11.1) C00016002
563 AZGP1, ZA2G, ZAG alpha-2-glycoprotein 1, zinc-binding C00016002
64343 AZI2, AZ2, NAP1, TILP 5-azacytidine induced 2 C00016002
578 BAK1, BAK, BAK-LIKE, BCL2L7, CDN1 BCL2-antagonist/killer 1 C00016002
581 BAX, BCL2L4 BCL2-associated X protein C00016002
27113 BBC3, JFY-1, JFY1, PUMA BCL2 binding component 3 C00016002
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00016002
12044 C00016002
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00016002
10018 BCL2L11, BAM, BIM, BOD BCL2-like 11 (apoptosis facilitator) C00016002
637 BID, FP497 BH3 interacting domain death agonist C00016002
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00016002
648 BMI1, FLVI2/BMI1, PCGF4, RNF51 BMI1 polycomb ring finger oncogene C00016002
1620 BRINP1, DBC1, DBCCR1, FAM5A bone morphogenetic protein/retinoic acid inducible neural-specific 1 C00016002
55299 BRIX1, BRIX, BXDC2 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) C00016002
686 BTD biotinidase (EC:3.5.1.12) C00016002
114904 C1QTNF6, CTFP6, CTRP6, ZACRP6 C1q and tumor necrosis factor related protein 6 C00016002
790 CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (EC:2.1.3.2 3.5.2.3 6.3.5.5) C00016002
285782 CAGE1, CT3, CT95, CTAG3, bA69L16.7 cancer antigen 1 C00016002
843 CASP10, ALPS2, FLICE2, MCH4 caspase 10, apoptosis-related cysteine peptidase (EC:3.4.22.63) C00016002
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00016002
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00016002
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00016002
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00016002
54897 CASZ1, CAS11, CST, SRG, ZNF693, dJ734G22.1 castor zinc finger 1 C00016002
6356 CCL11, SCYA11 chemokine (C-C motif) ligand 11 C00016002
8900 CCNA1 cyclin A1 C00016002
890 CCNA2, CCN1, CCNA cyclin A2 C00016002
891 CCNB1, CCNB cyclin B1 C00016002
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00016002
894 CCND2, KIAK0002 cyclin D2 C00016002
896 CCND3 cyclin D3 C00016002
898 CCNE1, CCNE cyclin E1 C00016002
729230 CCR2, CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R chemokine (C-C motif) receptor 2 C00016002
1234 CCR5, CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 chemokine (C-C motif) receptor 5 (gene/pseudogene) C00016002
1235 CCR6, BN-1, C-C_CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22 chemokine (C-C motif) receptor 6 C00016002
929 CD14 CD14 molecule C00016002
960 CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 CD44 molecule (Indian blood group) C00016002
4179 CD46, AHUS2, MCP, MIC10, TLX, TRA2.10 CD46 molecule, complement regulatory protein C00016002
994 CDC25B cell division cycle 25B (EC:3.1.3.48) C00016002
999 CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO cadherin 1, type 1, E-cadherin (epithelial) C00016002
1009 CDH11, CAD11, CDHOB, OB, OSF-4 cadherin 11, type 2, OB-cadherin (osteoblast) C00016002
1012 CDH13, CDHH, P105 cadherin 13 (EC:3.6.1.3) C00016002
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00016002
1019 CDK4, CMM3, PSK-J3 cyclin-dependent kinase 4 (EC:2.7.11.22) C00016002
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00016002
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00016002
1029 CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16 cyclin-dependent kinase inhibitor 2A C00016002
1030 CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) C00016002
1045 CDX2, CDX-3, CDX3 caudal type homeobox 2 C00016002
1046 CDX4 caudal type homeobox 4 C00016002
1051 CEBPB, C/EBP-beta, CRP2, IL6DBP, LAP, LIP, NF-IL6, TCF5 CCAAT/enhancer binding protein (C/EBP), beta C00016002
10752 CHL1, CALL, L1CAM2 cell adhesion molecule L1-like C00016002
1132 CHRM4, HM4, M4R cholinergic receptor, muscarinic 4 C00016002
1365 CLDN3, C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 claudin 3 C00016002
7122 CLDN5, AWAL, BEC1, CPETRL1, TMVCF claudin 5 C00016002
9074 CLDN6 claudin 6 C00016002
9073 CLDN8 claudin 8 C00016002
9080 CLDN9 claudin 9 C00016002
1192 CLIC1, G6, NCC27 chloride intracellular channel 1 C00016002
1191 CLU, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2 clusterin C00016002
1329 COX5B, COXVB cytochrome c oxidase subunit Vb (EC:1.9.3.1) C00016002
1387 CREBBP, CBP, KAT3A, RSTS CREB binding protein (EC:2.3.1.48) C00016002
1390 CREM, CREM-2, ICER, hCREM-2 cAMP responsive element modulator C00016002
1399 CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like C00016002
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00016002
1474 CST6 cystatin E/M C00016002
1490 CTGF, CCN2, HCS24, IGFBP8, NOV2 connective tissue growth factor C00016002
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00016002
1503 CTPS1, CTPS CTP synthase 1 (EC:6.3.4.2) C00016002
6376 CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin chemokine (C-X3-C motif) ligand 1 C00016002
1525 CXADR, CAR, CAR4/6, HCAR coxsackie virus and adenovirus receptor C00016002
6387 CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B chemokine (C-X-C motif) ligand 12 C00016002
9547 CXCL14, BMAC, BRAK, KEC, KS1, MIP-2g, MIP2G, NJAC, SCYB14 chemokine (C-X-C motif) ligand 14 C00016002
6374 CXCL5, ENA-78, SCYB5 chemokine (C-X-C motif) ligand 5 C00016002
7852 CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM chemokine (C-X-C motif) receptor 4 C00016002
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00016002
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00016002
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00016002
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00016002
1591 CYP24A1, CP24, CYP24, HCAI, P450-CC24 cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) C00016002
29785 CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 (EC:1.14.14.1) C00016002
13119 C00016002
147906 DACT3, DAPPER3, RRR1 dishevelled-binding antagonist of beta-catenin 3 C00016002
1612 DAPK1, DAPK death-associated protein kinase 1 (EC:2.7.11.1) C00016002
23604 DAPK2, DRP-1, DRP1 death-associated protein kinase 2 (EC:2.7.11.1) C00016002
131566 DCBLD2, CLCP1, ESDN discoidin, CUB and LCCL domain containing 2 C00016002
1630 DCC, CRC18, CRCR1, IGDCC1, MRMV1 deleted in colorectal carcinoma C00016002
1638 DCT, TRP-2, TYRP2 dopachrome tautomerase (EC:5.3.3.12) C00016002
10202 DHRS2, HEP27, SDR25C1 dehydrogenase/reductase (SDR family) member 2 C00016002
3337 DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1 DnaJ (Hsp40) homolog, subfamily B, member 1 C00016002
1789 DNMT3B, ICF, ICF1, M.HsaIIIB DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) C00016002
151871 DPPA2, CT100, ECAT15-2, PESCRG1 developmental pluripotency associated 2 C00016002
1843 DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10 dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) C00016002
1855 DVL1, DVL, DVL1L1, DVL1P1 dishevelled segment polarity protein 1 C00016002
1856 DVL2 dishevelled segment polarity protein 2 C00016002
1958 EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 early growth response 1 C00016002
1978 EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I eukaryotic translation initiation factor 4E binding protein 1 C00016002
1982 EIF4G2, AAG1, DAP5, NAT1, P97 eukaryotic translation initiation factor 4 gamma, 2 C00016002
1994 ELAVL1, ELAV1, HUR, Hua, MelG ELAV like RNA binding protein 1 C00016002
2002 ELK1 ELK1, member of ETS oncogene family C00016002
22936 ELL2 elongation factor, RNA polymerase II, 2 C00016002
133418 EMB embigin C00016002
8507 ENC1, CCL28, ENC-1, KLHL35, KLHL37, NRPB, PIG10, TP53I10 ectodermal-neural cortex 1 (with BTB domain) C00016002
2033 EP300, KAT3B, RSTS2, p300 E1A binding protein p300 (EC:2.3.1.48) C00016002
2045 EPHA7, EHK3, HEK11 EPH receptor A7 (EC:2.7.10.1) C00016002
2078 ERG, erg-3, p55 v-ets avian erythroblastosis virus E26 oncogene homolog C00016002
54206 ERRFI1, GENE-33, MIG-6, MIG6, RALT ERBB receptor feedback inhibitor 1 C00016002
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00016002
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00016002
2101 ESRRA, ERR1, ERRa, ERRalpha, ESRL1, NR3B1 estrogen-related receptor alpha C00016002
2104 ESRRG, ERR3, ERRgamma, NR3B3 estrogen-related receptor gamma C00016002
81889 FAHD1, C16orf36, YISKL fumarylacetoacetate hydrolase domain containing 1 (EC:3.7.1.5) C00016002
84985 FAM83A, BJ-TSA-9 family with sequence similarity 83, member A C00016002
355 FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 Fas cell surface death receptor C00016002
2203 FBP1, FBP fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) C00016002
8789 FBP2 fructose-1,6-bisphosphatase 2 (EC:3.1.3.11) C00016002
26291 FGF21 fibroblast growth factor 21 C00016002
2272 FHIT, AP3Aase, FRA3B fragile histidine triad (EC:3.6.1.29) C00016002
2350 FOLR2, BETA-HFR, FBP, FBP/PL-1, FR-BETA, FR-P3 folate receptor 2 (fetal) C00016002
3169 FOXA1, HNF3A, TCF3A forkhead box A1 C00016002
27023 FOXB1, FKH5, HFKH-5 forkhead box B1 C00016002
2296 FOXC1, ARA, FKHL7, FREAC-3, FREAC3, IGDA, IHG1, IRID1, RIEG3 forkhead box C1 C00016002
221937 FOXK1, FOXK1L forkhead box K1 C00016002
5349 FXYD3, MAT8, PLML FXYD domain containing ion transport regulator 3 C00016002
8322 FZD4, CD344, EVR1, FEVR, FZD4S, Fz-4, Fz4, FzE4, GPCR, hFz4 frizzled family receptor 4 C00016002
2597 GAPDH, G3PD, GAPD glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) C00016002
2623 GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT GATA binding protein 1 (globin transcription factor 1) C00016002
2624 GATA2, DCML, MONOMAC, NFE1B GATA binding protein 2 C00016002
2625 GATA3, HDR, HDRS GATA binding protein 3 C00016002
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00016002
8521 GCM1, GCMA, hGCMa glial cells missing homolog 1 (Drosophila) C00016002
9518 GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB growth differentiation factor 15 C00016002
2669 GEM, KIR GTP binding protein overexpressed in skeletal muscle C00016002
2798 GNRHR, GNRHR1, GRHR, HH7, LHRHR, LRHR gonadotropin-releasing hormone receptor C00016002
2878 GPX3, GPx-P, GSHPx-3, GSHPx-P glutathione peroxidase 3 (plasma) (EC:1.11.1.9) C00016002
2882 GPX7, CL683, GPX6, GPx-7, GSHPx-7, NPGPx glutathione peroxidase 7 (EC:1.11.1.9) C00016002
2891 GRIA2, GLUR2, GLURB, GluA2, GluR-K2, HBGR2 glutamate receptor, ionotropic, AMPA 2 C00016002
2946 GSTM2, GST4, GSTM, GSTM2-2, GTHMUS glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18) C00016002
2947 GSTM3, GST5, GSTB, GSTM3-3, GTM3 glutathione S-transferase mu 3 (brain) (EC:2.5.1.18) C00016002
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00016002
54676 GTPBP2 GTP binding protein 2 C00016002
3005 H1F0, H10, H1FV H1 histone family, member 0 C00016002
15043 C00016002
3065 HDAC1, GON-10, HD1, RPD3, RPD3L1 histone deacetylase 1 (EC:3.5.1.98) C00016002
3066 HDAC2, HD2, RPD3, YAF1 histone deacetylase 2 (EC:3.5.1.98) C00016002
8841 HDAC3, HD3, RPD3, RPD3-2 histone deacetylase 3 (EC:3.5.1.98) C00016002
10013 HDAC6, CPBHM, HD6 histone deacetylase 6 (EC:3.5.1.98) C00016002
3087 HHEX, HEX, HMPH, HOX11L-PEN, PRH, PRHX hematopoietically expressed homeobox C00016002
8290 HIST3H3, H3.4, H3/g, H3FT, H3t histone cluster 3, H3 C00016002
121504 HIST4H4, H4/p histone cluster 4, H4 C00016002
3141 HLCS, HCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) (EC:6.3.4.10 6.3.4.11 6.3.4.15 6.3.4.9) C00016002
23526 HMHA1, ARHGAP45, HA-1, HLA-HA1 histocompatibility (minor) HA-1 C00016002
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00016002
3166 HMX1, H6, NKX5-3 H6 family homeobox 1 C00016002
6928 HNF1B, FJHN, HNF-1B, HNF1beta, HNF2, HPC11, LF-B3, LFB3, MODY5, TCF-2, TCF2, VHNF1 HNF1 homeobox B C00016002
3181 HNRNPA2B1, HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, RNPA2, SNRPB1 heterogeneous nuclear ribonucleoprotein A2/B1 C00016002
3202 HOXA5, HOX1, HOX1.3, HOX1C homeobox A5 C00016002
3214 HOXB4, HOX-2.6, HOX2, HOX2F homeobox B4 C00016002
3231 HOXD1, HOX4, HOX4G, Hox-4.7 homeobox D1 C00016002
3248 HPGD, 15-PGDH, PGDH, PGDH1, PHOAR1, SDR36C1 hydroxyprostaglandin dehydrogenase 15-(NAD) (EC:1.1.1.141) C00016002
3320 HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2 heat shock protein 90kDa alpha (cytosolic), class A member 1 C00016002
3305 HSPA1L, HSP70-1L, HSP70-HOM, HSP70T, hum70t heat shock 70kDa protein 1-like C00016002
3313 HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74 heat shock 70kDa protein 9 (mortalin) C00016002
27429 HTRA2, OMI, PARK13, PRSS25 HtrA serine peptidase 2 (EC:3.4.21.108) C00016002
3381 IBSP, BNSP, BSP, BSP-II, SP-II integrin-binding sialoprotein C00016002
3458 IFNG, IFG, IFI interferon, gamma C00016002
11020 IFT27, RABL4, RAYL intraflagellar transport 27 homolog (Chlamydomonas) C00016002
3486 IGFBP3, BP-53, IBP3 insulin-like growth factor binding protein 3 C00016002
22806 IKZF3, AIO, AIOLOS, ZNFN1A3 IKAROS family zinc finger 3 (Aiolos) C00016002
3592 IL12A, CLMF, IL-12A, NFSK, NKSF1, P35 interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) C00016002
3593 IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2 interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) C00016002
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00016002
54450 C00016002
3559 IL2RA, CD25, IDDM10, IL2R, TCGFR interleukin 2 receptor, alpha C00016002
3572 IL6ST, CD130, CDW130, GP130, IL-6RB interleukin 6 signal transducer (gp130, oncostatin M receptor) C00016002
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00016002
3619 INCENP inner centromere protein antigens 135/155kDa C00016002
3625 INHBB inhibin, beta B C00016002
3394 IRF8, H-ICSBP, ICSBP, ICSBP1, IRF-8 interferon regulatory factor 8 C00016002
3683 ITGAL, CD11A, LFA-1, LFA1A integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) C00016002
3684 ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6 integrin, alpha M (complement component 3 receptor 3 subunit) C00016002
3714 JAG2, HJ2, SER2 jagged 2 C00016002
3717 JAK2, JTK10, THCYT3 Janus kinase 2 (EC:2.7.10.2) C00016002
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00016002
3726 JUNB, AP-1 jun B proto-oncogene C00016002
3778 KCNMA1, BKTM, KCa1.1, MaxiK, SAKCA, SLO, SLO-ALPHA, SLO1, bA205K10.1, mSLO1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 C00016002
9682 KDM4A, JHDM3A, JMJD2, JMJD2A, TDRD14A lysine (K)-specific demethylase 4A (EC:1.14.11.-) C00016002
23030 KDM4B, JMJD2B, TDRD14B lysine (K)-specific demethylase 4B C00016002
688 KLF5, BTEB2, CKLF, IKLF Kruppel-like factor 5 (intestinal) C00016002
354 KLK3, APS, KLK2A1, PSA, hK3 kallikrein-related peptidase 3 (EC:3.4.21.77) C00016002
16638 C00016002
10219 KLRG1, 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE killer cell lectin-like receptor subfamily G, member 1 C00016002
3837 KPNB1, IMB1, IPO1, IPOB, Impnb, NTF97 karyopherin (importin) beta 1 C00016002
3858 KRT10, BCIE, BIE, CK10, EHK, K10, KPP keratin 10 C00016002
3856 KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO keratin 8 C00016002
27074 LAMP3, CD208, DC_LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403 lysosomal-associated membrane protein 3 C00016002
51176 LEF1, LEF-1, TCF10, TCF1ALPHA, TCF7L3 lymphoid enhancer-binding factor 1 C00016002
3952 LEP, LEPD, OB, OBS leptin C00016002
3954 LETM1 leucine zipper-EF-hand containing transmembrane protein 1 C00016002
3988 LIPA, CESD, LAL lipase A, lysosomal acid, cholesterol esterase (EC:3.1.1.13) C00016002
4017 LOXL2, LOR2, WS9-14 lysyl oxidase-like 2 (EC:1.4.3.-) C00016002
116135 LRRC3B, LRP15 leucine rich repeat containing 3B C00016002
23639 LRRC6, CILD19, LRTP, TSLRP leucine rich repeat containing 6 C00016002
110454 C00016002
4069 LYZ, LZM lysozyme (EC:3.2.1.17) C00016002
9935 MAFB, KRML, MCTO v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B C00016002
81631 MAP1LC3B, ATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a microtubule-associated protein 1 light chain 3 beta C00016002
5604 MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) C00016002
5871 MAP4K2, BL44, GCK, RAB8IP mitogen-activated protein kinase kinase kinase kinase 2 (EC:2.7.11.1) C00016002
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00016002
1432 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA mitogen-activated protein kinase 14 (EC:2.7.11.24) C00016002
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00016002
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00016002
5601 MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK mitogen-activated protein kinase 9 (EC:2.7.11.24) C00016002
4139 MARK1, MARK, Par-1c, Par1c MAP/microtubule affinity-regulating kinase 1 (EC:2.7.11.1 2.7.11.26) C00016002
8932 MBD2, DMTase, NY-CO-41 methyl-CpG binding domain protein 2 C00016002
55777 MBD5, MRD1 methyl-CpG binding domain protein 5 C00016002
4170 MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT myeloid cell leukemia sequence 1 (BCL2-related) C00016002
4172 MCM3, HCC5, P1-MCM3, P1.h, RLFB minichromosome maintenance complex component 3 (EC:3.6.4.12) C00016002
4176 MCM7, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146 minichromosome maintenance complex component 7 (EC:3.6.4.12) C00016002
4204 MECP2, AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT methyl CpG binding protein 2 (Rett syndrome) C00016002
4205 MEF2A, ADCAD1, RSRFC4, RSRFC9, mef2 myocyte enhancer factor 2A C00016002
4255 MGMT O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) C00016002
4256 MGP, MGLAP, NTI matrix Gla protein C00016002
4292 MLH1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1 mutL homolog 1 C00016002
4321 MMP12, HME, ME, MME, MMP-12 matrix metallopeptidase 12 (macrophage elastase) (EC:3.4.24.65) C00016002
4322 MMP13, CLG3, MANDP1 matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-) C00016002
4353 MPO myeloperoxidase (EC:1.11.2.2) C00016002
2206 MS4A2, APY, ATOPY, FCER1B, FCERI, IGEL, IGER, IGHER, MS4A1 membrane-spanning 4-domains, subfamily A, member 2 C00016002
4547 MTTP, ABL, MTP microsomal triglyceride transfer protein C00016002
4585 MUC4, ASGP, HSA276359, MUC-4 mucin 4, cell surface associated C00016002
4599 MX1, IFI-78K, IFI78, MX, MxA myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) C00016002
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00016002
4621 MYH3, HEMHC, MYHC-EMB, MYHSE1, SMHCE myosin, heavy chain 3, skeletal muscle, embryonic C00016002
23040 MYT1L, NZF1, ZC2HC4B myelin transcription factor 1-like C00016002
4666 NACA, NACA1 nascent polypeptide-associated complex alpha subunit (EC:5.3.99.3) C00016002
4690 NCK1, NCK, NCKalpha, nck-1 NCK adaptor protein 1 C00016002
8031 NCOA4, ARA70, ELE1, PTC3, RFG nuclear receptor coactivator 4 C00016002
9437 NCR1, CD335, LY94, NK-p46, NKP46 natural cytotoxicity triggering receptor 1 C00016002
4712 NDUFB6, B17, CI NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa (EC:1.6.5.3 1.6.99.3) C00016002
4718 NDUFC2, B14.5b, CI-B14.5b, HLC-1, NADHDH2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa C00016002
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00016002
23420 NOMO1, Nomo, PM5 NODAL modulator 1 C00016002
4851 NOTCH1, TAN1, hN1 notch 1 C00016002
4881 NPR1, ANPRA, ANPa, GUC2A, GUCY2A, NPRA natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (EC:4.6.1.2) C00016002
1728 NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) C00016002
2908 NR3C1, GCCR, GCR, GR, GRL nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) C00016002
3164 NR4A1, GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3 nuclear receptor subfamily 4, group A, member 1 C00016002
8829 NRP1, BDCA4, CD304, NP1, NRP, VEGF165R neuropilin 1 C00016002
100506658 OCLN, BLCPMG occludin (EC:2.1.1.67) C00016002
4953 ODC1, ODC ornithine decarboxylase 1 (EC:4.1.1.17) C00016002
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00016002
301164 C00016002
57526 PCDH19, EFMR, EIEE9 protocadherin 19 C00016002
5166 PDK4 pyruvate dehydrogenase kinase, isozyme 4 (EC:2.7.11.2) C00016002
57162 PELI1 pellino E3 ubiquitin protein ligase 1 C00016002
18630 C00016002
5241 PGR, NR3C3, PR progesterone receptor C00016002
5293 PIK3CD, P110DELTA, PI3K, p110D phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (EC:2.7.1.153) C00016002
5292 PIM1, PIM pim-1 oncogene (EC:2.7.11.1) C00016002
51426 POLK, DINB1, DINP, POLQ polymerase (DNA directed) kappa (EC:2.7.7.7) C00016002
5460 POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 POU class 5 homeobox 1 C00016002
5478 PPIA, CYPA, CYPH peptidylprolyl isomerase A (cyclophilin A) (EC:5.2.1.8) C00016002
81706 PPP1R14C, CPI17-like, KEPI, NY-BR-81 protein phosphatase 1, regulatory (inhibitor) subunit 14C C00016002
5507 PPP1R3C, PPP1R5 protein phosphatase 1, regulatory subunit 3C C00016002
5052 PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2 peroxiredoxin 1 (EC:1.11.1.15) C00016002
5590 PRKCZ, PKC-ZETA, PKC2 protein kinase C, zeta (EC:2.7.11.13) C00016002
55015 PRPF39 pre-mRNA processing factor 39 C00016002
5645 PRSS2, TRY2, TRY8, TRYP2 protease, serine, 2 (trypsin 2) (EC:3.4.21.4) C00016002
5692 PSMB4, HN3, HsN3, PROS-26, PROS26 proteasome (prosome, macropain) subunit, beta type, 4 (EC:3.4.25.1) C00016002
5728 PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) C00016002
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00016002
5741 PTH, PTH1 parathyroid hormone C00016002
26191 PTPN22, LYP, LYP1, LYP2, PEP, PTPN8 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (EC:3.1.3.48) C00016002
5820 PVT1, LINC00079, NCRNA00079 Pvt1 oncogene (non-protein coding) C00016002
29108 PYCARD, ASC, CARD5, TMS, TMS-1, TMS1 PYD and CARD domain containing C00016002
5879 RAC1, Rac-1, TC-25, p21-Rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) C00016002
5901 RAN, ARA24, Gsp1, TC4 RAN, member RAS oncogene family C00016002
5915 RARB, HAP, NR1B2, RRB2 retinoic acid receptor, beta C00016002
5916 RARG, NR1B3, RARC retinoic acid receptor, gamma C00016002
5918 RARRES1, LXNL, TIG1 retinoic acid receptor responder (tazarotene induced) 1 C00016002
11186 RASSF1, 123F2, NORE2A, RASSF1A, RDA32, REH3P21 Ras association (RalGDS/AF-6) domain family member 1 C00016002
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00016002
116362 RBP7, CRBP4, CRBPIV retinol binding protein 7, cellular C00016002
55920 RCC2, TD-60 regulator of chromosome condensation 2 C00016002
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00016002
85004 RERG RAS-like, estrogen-regulated, growth inhibitor C00016002
5978 REST, NRSF, XBR RE1-silencing transcription factor C00016002
388 RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 ras homolog family member B C00016002
55178 RNMTL1 RNA methyltransferase like 1 (EC:2.1.1.-) C00016002
6175 RPLP0, L10E, LP0, P0, PRLP0, RPP0 ribosomal protein, large, P0 C00016002
126638 RPTN repetin C00016002
10692 RRH retinal pigment epithelium-derived rhodopsin homolog C00016002
6274 S100A3, S100E S100 calcium binding protein A3 C00016002
1901 S1PR1, CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1 sphingosine-1-phosphate receptor 1 C00016002
9294 S1PR2, AGR16, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2 sphingosine-1-phosphate receptor 2 C00016002
1903 S1PR3, EDG-3, EDG3, LPB3, S1P3 sphingosine-1-phosphate receptor 3 C00016002
45384 C00016002
6323 SCN1A, EIEE6, FEB3, FEB3A, FHM3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI sodium channel, voltage-gated, type I, alpha subunit C00016002
10427 SEC24B, SEC24 SEC24 family member B C00016002
6403 SELP, CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL selectin P (granule membrane protein 140kDa, antigen CD62) C00016002
5413 SEPT5, CDCREL, CDCREL-1, CDCREL1, H5, HCDCREL-1, PNUTL1 septin 5 (EC:3.1.5.1) C00016002
5268 SERPINB5, PI5, maspin serpin peptidase inhibitor, clade B (ovalbumin), member 5 C00016002
6418 SET, 2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA SET nuclear oncogene C00016002
6421 SFPQ, POMP100, PSF splicing factor proline/glutamine-rich C00016002
6422 SFRP1, FRP, FRP-1, FRP1, FrzA, SARP2 secreted frizzled-related protein 1 C00016002
6423 SFRP2, FRP-2, SARP1, SDF-5 secreted frizzled-related protein 2 C00016002
6424 SFRP4, FRP-4, FRPHE, sFRP-4 secreted frizzled-related protein 4 C00016002
6425 SFRP5, SARP3 secreted frizzled-related protein 5 C00016002
6566 SLC16A1, HHF7, MCT, MCT1 solute carrier family 16 (monocarboxylate transporter), member 1 C00016002
6506 SLC1A2, EAAT2, GLT-1 solute carrier family 1 (glial high affinity glutamate transporter), member 2 C00016002
6576 SLC25A1, CTP, D2L2AD, SEA, SLC20A3 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 C00016002
6518 SLC2A5, GLUT-5, GLUT5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 C00016002
113829 SLC35A4 solute carrier family 35, member A4 C00016002
54407 SLC38A2, ATA2, PRO1068, SAT2, SNAT2 solute carrier family 38, member 2 C00016002
25800 SLC39A6, LIV-1 solute carrier family 39 (zinc transporter), member 6 C00016002
6528 SLC5A5, NIS, TDH1 solute carrier family 5 (sodium/iodide cotransporter), member 5 C00016002
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00016002
6623 SNCG, BCSG1, SR synuclein, gamma (breast cancer-specific protein 1) C00016002
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00016002
6667 SP1 Sp1 transcription factor C00016002
6670 SP3, SPR2 Sp3 transcription factor C00016002
10653 SPINT2, DIAR3, HAI-2, HAI2, Kop, PB serine peptidase inhibitor, Kunitz type, 2 C00016002
89845 ABCC10, EST182763, MRP7, SIMRP7 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 C00016002
20941 C00016002
20945 C00016002
6867 TACC1, Ga55 transforming, acidic coiled-coil containing protein 1 C00016002
6925 TCF4, E2-2, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4, bHLHb19 transcription factor 4 C00016002
21580 C00016002
7015 TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT telomerase reverse transcriptase (EC:2.7.7.49) C00016002
7021 TFAP2B, AP-2B, AP2-B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) C00016002
7022 TFAP2C, AP2-GAMMA, ERF1, TFAP2G, hAP-2g transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) C00016002
7031 TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 C00016002
7980 TFPI2, PP5, REF1, TFPI-2 tissue factor pathway inhibitor 2 C00016002
7040 TGFB1, CED, DPD1, LAP, TGFB, TGFbeta transforming growth factor, beta 1 C00016002
7048 TGFBR2, AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30) C00016002
51298 THEG, CT56, THEG1 theg spermatid protein C00016002
7082 TJP1, ZO-1 tight junction protein 1 C00016002
8795 TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 tumor necrosis factor receptor superfamily, member 10b C00016002
7132 TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60 tumor necrosis factor receptor superfamily, member 1A C00016002
8744 TNFSF9, 4-1BB-L, CD137L tumor necrosis factor (ligand) superfamily, member 9 C00016002
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00016002
94241 TP53INP1, SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1 tumor protein p53 inducible nuclear protein 1 C00016002
8626 TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L tumor protein p63 C00016002
7170 TPM3, CAPM1, CFTD, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5, TPMsk3, TRK, hscp30 tropomyosin 3 C00016002
7171 TPM4 tropomyosin 4 C00016002
7178 TPT1, HRF, TCTP, p02, p23 tumor protein, translationally-controlled 1 C00016002
22974 TPX2, C20orf1, C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, REPP86, p100 TPX2, microtubule-associated C00016002
8717 TRADD, Hs.89862 TNFRSF1A-associated via death domain C00016002
7225 TRPC6, FSGS2, TRP6 transient receptor potential cation channel, subfamily C, member 6 C00016002
7248 TSC1, LAM, TSC tuberous sclerosis 1 C00016002
7253 TSHR, CHNG1, LGR3, hTSHR-I thyroid stimulating hormone receptor C00016002
108314 C00016002
7298 TYMS, HST422, TMS, TS thymidylate synthetase (EC:2.1.1.45) C00016002
7301 TYRO3, BYK, Dtk, RSE, Sky, Tif TYRO3 protein tyrosine kinase (EC:2.7.10.1) C00016002
7345 UCHL1, NDGOA, PARK5, PGP_9.5, PGP9.5, PGP95, Uch-L1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (EC:3.4.19.12) C00016002
81622 UNC93B1, IIAE1, UNC93, UNC93B, Unc-93B1 unc-93 homolog B1 (C. elegans) C00016002
6845 VAMP7, SYBL1, TI-VAMP, TIVAMP, VAMP-7 vesicle-associated membrane protein 7 C00016002
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00016002
7421 VDR, NR1I1 vitamin D (1,25- dihydroxyvitamin D3) receptor C00016002
7431 VIM, CTRCT30 vimentin C00016002
22305 C00016002
55737 VPS35, MEM3, PARK17 vacuolar protein sorting 35 homolog (S. cerevisiae) C00016002
23559 WBP1, WBP-1 WW domain binding protein 1 C00016002
11197 WIF1, WIF-1 WNT inhibitory factor 1 C00016002
51741 WWOX, D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SDR41C1, WOX1 WW domain containing oxidoreductase (EC:1.1.1.-) C00016002
7503 XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 X inactive specific transcript (non-protein coding) C00016002
7547 ZIC3, HTX, HTX1, VACTERLX, ZNF203 Zic family member 3 C00016002
51364 ZMYND10, BLU, FLU zinc finger, MYND-type containing 10 C00016002
9753 ZSCAN12, ZFP96, ZNF29K1, ZNF305, ZNF96, dJ29K1.2 zinc finger and SCAN domain containing 12 C00016002
1758 DMP1, ARHP, ARHR, DMP-1 dentin matrix acidic phosphoprotein 1 C00000800
5251 PHEX, HPDR, HPDR1, HYP, HYP1, LXHR, PEX, XLH phosphate regulating endopeptidase homolog, X-linked C00000800
6574 SLC20A1, GLVR1, Glvr-1, PIT1, PiT-1 solute carrier family 20 (phosphate transporter), member 1 C00000800
6575 SLC20A2, GLVR-2, GLVR2, IBGC1, IBGC3, MLVAR, PIT-2, PIT2, RAM1 solute carrier family 20 (phosphate transporter), member 2 C00000800

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (66)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
P14416
P31645
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#600430 Brachydactyly-mental retardation syndrome; bdmr P56524
#300615 Brunner syndrome P21397
#612591 Colorectal cancer, susceptibility to, 10; crcs10 P28340
#300882 Cornelia de lange syndrome 5; cdls5 Q9BY41
#162800 Cyclic neutropenia P08246
#219700 Cystic fibrosis; cf P13569
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 P04626
#610015 Glutamine deficiency, congenital P15104
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#614441 Hypertrophic osteoarthropathy, primary, autosomal recessive, 2; phoar2 Q92959
#603932 Intervertebral disc disease; idd P14780
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
#615381 Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome; mdpl P28340
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#126200 Multiple sclerosis, susceptibility to; ms P08575
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#172700 Pick disease of brain P10636
#170100 Prolidase deficiency P12955
#607276 Resting heart rate, variation in P08588
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#614831 Spinocerebellar ataxia, autosomal recessive 13; scar13 Q13255
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#190300 Tremor, hereditary essential, 1; etm1 P35462
#277180 Vas deferens, congenital bilateral aplasia of; cbavd P13569
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#309585 Wilson-turner x-linked mental retardation syndrome; wts Q9BY41
#112100 Yt blood group antigen P22303

KEGG DISEASE (50)

KEGG name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H01119 Prolidase deficiency (PD) P12955 (related)
H00218 Cystic fibrosis (CF) P13569 (related)
H00933 Hereditary pancreatitis P13569 (related)
H01033 Congenital bilateral absence of vas deferens P13569 (related)
H00025 Penile cancer P14780 (related)
P35354 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00923 Congenital systemic glutamine deficiency (CSGD) P15104 (related)
H00548 Brunner syndrome P21397 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00561 Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome P56524 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00021 Renal cell carcinoma Q16790 (marker)

Diseases related to CTD interactions

66 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000014 Abnormalities, Drug-Induced C00016002
D000015 Abnormalities, Multiple C00016002
C538231 Adenocarcinoma of lung C00016002
D001848 Bone Diseases, Developmental C00016002
D019970 Cocaine-Related Disorders C00016002
D004701 Endocrine Gland Neoplasms C00016002
D005909 Glioblastoma C00016002
D015470 Leukemia, Myeloid, Acute C00016002
D008545 Melanoma C00016002
D009101 Multiple Myeloma C00016002
D010051 Ovarian Neoplasms C00016002
D010190 Pancreatic Neoplasms C00016002
D010490 Pericardial Effusion C00016002
D049188 Prenatal Injuries C00016002
D055728 Primary Myelofibrosis C00016002
D011471 Prostatic Neoplasms C00016002
D000141 Acidosis, Renal Tubular C00000800
D058186 Acute Kidney Injury C00000800
D017088 AIDS-Related Opportunistic Infections C00000800
D001008 Anxiety Disorders C00000800
D003092 Colitis C00000800
D003586 Cytomegalovirus Infections C00000800
D017726 Cytomegalovirus Retinitis C00000800
D018500 Diabetes Insipidus, Nephrogenic C00000800
D064420 Drug-Related Side Effects and Adverse Reactions C00000800
D004421 Dystonia C00000800
D020803 Encephalitis, Herpes Simplex C00000800
D004830 Epilepsy, Tonic-Clonic C00000800
D005334 Fever C00000800
D005921 Glomerulonephritis C00000800
D006333 Heart Failure C00000800
D006402 Hematologic Diseases C00000800
D006417 Hematuria C00000800
D006525 Hepatitis, Viral, Human C00000800
D006566 Herpesviridae Infections C00000800
D015658 HIV Infections C00000800
C538117 Human Herpesvirus 6 encephalitis C00000800
D006934 Hypercalcemia C00000800
D006996 Hypocalcemia C00000800
D007008 Hypokalemia C00000800
D007010 Hyponatremia C00000800
D017674 Hypophosphatemia C00000800
D007015 Hypophosphatemia, Familial C00000800
D007674 Kidney Diseases C00000800
D007676 Kidney Failure, Chronic C00000800
D007683 Kidney Tubular Necrosis, Acute C00000800
D008275 Magnesium Deficiency C00000800
D008582 Meningitis, Aseptic C00000800
D009120 Muscle Cramp C00000800
D009190 Myelodysplastic Syndromes C00000800
D009325 Nausea C00000800
D009395 Nephritis, Interstitial C00000800
D009404 Nephrotic Syndrome C00000800
D009443 Neuritis C00000800
D009503 Neutropenia C00000800
D010292 Paresthesia C00000800
D010409 Penile Diseases C00000800
D011141 Polyuria C00000800
D051437 Renal Insufficiency C00000800
D015882 Retinal Necrosis Syndrome, Acute C00000800
D012173 Retinitis C00000800
D012640 Seizures C00000800
D013035 Spasm C00000800
D013746 Tetany C00000800
D014605 Uveitis C00000800
D014883 Water-Electrolyte Imbalance C00000800